Temporal Data Analysis and
Electronic Health Records
Ben Shneiderman, Catherine Plaisant,
Taowei David Wang, Kris Wongsuphasawat
{ben,plaisant,tw7,kristw}@cs.umd.edu
LifeLines: Patient Histories
www.cs.umd.edu/hcil/lifelines
Lifelines and Improvements
Plaisant CHI 96, AMIA 98
I2b2 (Murphy AMIA 07)
Lifelines and Improvements
Plaisant CHI 96, AMIA 98
Bade CHI 2004
I2b2 (Murphy AMIA 07)
Specification of Temporal Abstractions
Shahar 1999
Powsner & Tufte, 1994
Post 2007
PatternFinder in Amalga
1) LifeLines2: Align-Rank-Filter
- Multiple records simultaneously visible
- Align by
sentinel events
- Rank by
frequency
- Filter by
events
LifeLines2: Contrast+Creatinine
LifeLines2: Contrast+Creatinine
LifeLines2: Heparin-Induced Thrombocytopenia
LifeLines2: Heparin-Induced Thrombocytopenia
2) Similan: Find similar patients
•
•
•
In terms of ?
Not in terms of demographic information
• Age, gender, etc.
But in terms of patient histories
Events
Patient#1
Stomach Pain
time
Vomitting
Diarrhea
Similan: Find similar patients
•
How?
• Similarity Measure
• Between pairs of patients
• Score ranges from 0 to 1. (Most similar = 1)
• Users select one target patient
Similan: Find similar patients
Patient #1
(target)
Patient #2
0.80
Patient #3
0.63
Patient #4
0.96
Patient #5
0.77
Similan: Find similar patients
Patient #1
(target)
Patient #4
0.96
Patient #2
0.80
Patient #5
0.77
Patient #3
0.63
similar
Challenge
•
What is “similar”? depends on users/tasks
Patient#1
(target)
A
B
C
swapping
Patient#2
A
B
C
Patient#3
missing
B
A
Patient#4
A
time
B
Time difference
C
C
Mix&Match Measure
•
User customizable similarity measure
Missing Event
Patient#1
(target)
C
A
B
C
Patient#2
A
B
C
Extra Event
Matched Events
Match Score = F(∆ time)
Number of Mismatches = Missing + Extra
Number of Swapping*
B
}
Total Score
0 to 1
Similan: Find Similar Patients
Take Away Messages
Medical Record & other temporal event
exploration is possible for:
1) pattern discovery
2) comparison of groups
3) similar event records
Thanks for collaboration with
Washington Hospital Center
www.cs.umd.edu/hcil/lifelines2
www.cs.umd.edu/hcil/similan