Q Quantitative Analysis Quenching –

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Q
3
Quantitative Analysis
Chemical Structure and the Generation of an Allergic Reaction
Statistics in Immunotoxicology
3
Quenching
Quantitative structure–activity relationships (QSARs)
relate physicochemical properties of haptens to their
relative ability to cause allergy in such a way that the
potency of the allergen can be predicted. SARs omit
the quantitative element of this, simply indicating in
binary fashion whether or not a chemical has the capacity to behave as an allergen.
Quenching is the inhibition or elimination of one process by another process. The stimulated emission of a
laser oscillator can be quenched by a pulse of radiation
of the same frequency traversing the oscillator in a
different direction. This pulse induces the excited
ions to emit radiation in a direction apart from the
oscillating mode, and hence the oscillation is decreased.
Viability, Cell
3
Quantitative Structure–Activity
Relationships (QSARs)
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