AbstractID: 9432 Title: Acceptance and Commissioning of AcQSim Using AAPM TG-66 Guidelines. The Quality Assurance (QA) guidelines for Computed Tomography (CT) scanners have been well established through AAPM Diagnostic X- ray imaging committee Task Group Report 2. However, for CT- Simulator or AcQsim there are no established guidelines for acceptance & periodic QA. Task Group Report 66 (in press) from AAPM is first such document in literature to address this important topic. Based on the recommendation of TG-66, recently we commissioned AcQsin in our department. Following commissioning process was performed for Quality assurance of AcQsim. A. Evaluation of Digitally Reconstructed Radiograph (DRRs) for 1.Spatial & contrast resolution, 2.Geometric accuracy 3. Hardcopy quality & accuracy. B. Spatial & Geometric accuracy tests for 1.Image input tests to planning systems. 2.Structure delineation & accuracy. 3.Linear Accelerator definition, 4.Accuracy of isocenter calculation & movement. C. The AcQsim lasers QA 1.Gantry laser accuracy, 2.Vertical wall laser calibration and accuracy 3.Overhead or Sagittal laser calibration & movement accuracy D.Couch & Table top movement accuracy 1.Tabletop level & orthogonal with respect to imaging plane. 2.Table indexing & position accuracy. E.Generation of RED curve for planning system using RMI phantom. These acceptance tests indicated results within protocol tolerance limits, including the laser alignment accuracy within ±0.5mm, DRR divergence and spatial accuracy within ±1mm, table top indexing accuracy was better than 0.5mm, and the RED curves on our planning systems indicated linear pattern. 1