AbstractID: 8138 Title: Quality Assurance of MVCT imaging The TomoTherapy system (TomoTherapy, Inc., Madison, WI) is designed to deliver intensity modulated radiation therapy using a helical tomotherapy approach. In addition, megavoltage computed tomography (MVCT) images can be acquired with the system. MVCT images can be used to check the positioning of the patient prior to treatment. The acquired MVCT image is registered with planning CT to determine if corrections to the patient position are required. Upon acceptance the registration accuracy and precision should be evaluated. Phantombased test are well suited for these tests. In addition the precision of registering clinical images should be evaluated. Standard phantom test can be used to monitor the image quality of MVCT images. The image noise, Hounsfield unit (HU) consistency, image uniformity, and resolution can be tested. In addition the imaging dose should be monitored on a routine basis. A daily and monthly QA procedure can be implemented to monitor the consistency of all relevant procedures. On a daily basis a phantom-based test patient can be scanned to test the consistency of the image registration. This image can also be inspected for gross image artifacts. On a monthly basis a scan of a modular phantom can be used to monitor image noise, Hounsfield units, image uniformity and resolution. The imaging dose can be measured simultaneously. MVCT images are suitable for accurate dose recalculations. This requires the acquisition of a MVCT HU to electron density calibration curve. The accuracy of this calibration should be tested using an inhomogeneous rigid phantom. Educational Objectives: 1) Identify tests to measure relevant QA parameters 2) Understand the difference between the inherent system and clinical accuracy and precision 3) Identify and implement test procedure for routine monitoring of relevant QA parameters Conflict of interest: Research agreement with TomoTherapy, Inc.