RASHTRASANT TUKADOJI MAHARAJ NAGPUR UNIVERSITY NAGPUR DEPARTMENT OF PHARMACEUTICAL SCIENCES TENDER NOTICE No. Pharm/DST-SERB/Equip/594 Date: 29.11.2013 Sealed Tenders are invited for purchase of equipment under DST-SERB Program (SB/EMEQ-073/2013), in Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur-440033 from Manufacturers /Dealers / Sole Authorised distributors / Sole agents. Equipment: Semi Preparative HPLC System The details of the tender form can be downloaded from www.nagpuruniversity.org. The tender form containing terms and conditions and complete specifications of the above equipment can be obtained from the office of The Head, Department of Pharmaceutical Sciences during office hours. The schedule is as given below (on working days only): a) Sale of blank tender form: 02.12.2013 to 23.12.2013. b) Submission of tender form: up to 05:30 PM on 23.12.2013. c) Opening of tender form: Envelope No. 1 on 24.12.2013 (02:00 PM) and envelope No. 2 on 27.12.2013 (04:30 PM) at Department of Pharmaceutical Sciences. Notes: i. Blank tender form will be issued after receiving demand draft of any Nationalized/Schedule bank of Rs. 1000/- in favour of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur - 440 033. ii. Earnest Money Deposit (EMD) in the form of Demand Draft of any Nationalised/Schedule bank of 1% of the cost of items drawn in favour of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur440 033, should be submitted in Envelope No. 1 (Technical Bid). iii. The details like, income tax certificate, VAT registration and clearance, authorization from the manufacturers, previous experience, and technical specification should be submitted in Envelope No. 1 (Technical Bid). iv. Price bid should be submitted in Envelope No. 2 (Price Bid). v. Envelope No. 1 and 2 should be submitted in Envelope No. 3. The Head, Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur-440033 (MS) India reserves the right to reject any or all of the tenders without assigning any reasons thereof. Head Department of Pharmaceutical Sciences Price Rs. 1000/- Tender Form Tender Form for Supply of Equipment Under SERB-DST Project Contact Head Department of Pharmaceutical Sciences Rashtrasant Tukadoji Maharaj Nagpur University University Campus Nagpur -440 033 Ph. No. (0712) 2500355/ 2500324 RASHTRASANT TUKADOJI MAHARAJ NAGPUR UNIVERSITY, NAGPUR DEPARTMENT OF PHARMACEUTICAL SCIENCES Details of equipment to be purchased under DST-SERB program Vide letter No. 1829, dated 19.10.2013 of Development Cell Technical Specifications for Semi Preparative HPLC System Two Individual Solvent Delivery Units – 2 No’s Gradient Mixer – Vendor to quote for both Analytical & SemiPrep/Preparative Mixer Technical Specifications Must be capable of delivering semi-preparative and analytical flow rates Series/parallel type double plunger pumping mechanism The flow rate should be set between 0.001 to 20 ml/min for Each pump Flow rate accuracy setting should be less than ±1% or 10ul/min ( 0.1ml/min- 5ml/min) Flow rate precision should be less than 0.3% RSD The maximum discharge pressure should be 7100Psi It must be capable of standalone operation Composition accuracy _+ 0.5% ( independent of back pressure) Composition range 0-100% It should support the constant pressure solvent delivery Uniform mixing for both analytical and semi prep flow rates. It must have a leak sensor as a safety feature Error status shall be transferred to the operating software Sample Injecting System. Manual injector with 20ul loop and 25uL syringe and automatic start for analytical 1 ml, 2ml ,5ml sample loops with suitable 1 ml, 2ml ,5ml syringes for semi preparative Injector mounting kit Photo Diode Array Detector (PDA Detector) Wave length range 190-800 nm Light source – Deuterium lamp Spectral resolution- 1.2nm per photodiode with total of 512 diodes. The flow cell must be temperature controlled from ambient + 5ºC to 50ºC Wavelength accuracy must be ±1 nm maximum 1 Wavelength reproducibility must be +0.1 nm Drift should be less than 0.5 x 10-4 AU/Hour Noise level must be ±0.3 x1 0-5 AU Path length up to 10mm. Cell volume 8 - 10ul Multi Holder Kit/Stand… Holder should be able to mount Analytical column, Semi Column Switching Valve To seamless switch over between semi preparative column Flow cell Preparative flow cell with variable optical path length. (0.5mm) Standard flow cell to be with the detector for analytical applications. Reservoir Tray 4 No’s Solvent Bottles along with Tray to keep the solvent preparative column, Rheodyne Injector, column Switching valve, flow selection valve etc.. and analytical column. bottles. System Controller It should function as a communication bus module with data buffering capability It should acquire up to 24 hours for one analysis, at 500ms sampling rate It must be controllable from a web-based interface via a network. It allows the system to be controlled, monitored and maintained via Internet Explorer Web browser It must be compatible with wireless networking It must come with Expert function in that if pressure falls below specified value, the expert function will automatically purge the mobile phase It should store up to 20 analysis files with a total up to 400 steps of time programs Software Operation of the system should be very easy and intuitive via a state-of-the-art 32 bit Win XP based software It should cover full one-point digital instrument control, qualitative and quantitative processing, report creation and self-diagnosis The reporting format should be flexible and easy to use in any desired format The data can be converted to other formats. Spread Sheet software and word-processing software can be readily 2 employed to provide data in tables or graphs through industry standard protocols The software should allow automatic execution of system checks, auto-purge and baseline checks Software must have its own log files for complete audit trails Single access point for system administration, data acquisition, post run analysis and long term data management. Fraction Collector Columns Essential Accessories Should be able to collect small and large fractions Flexible collection methods Racks to be provided for 20ml and 32ml vials for collecting fractions 100 vials to be provided Fractions to be collected by time, volume peak, peak collection by level, slope , or sub fractions by time. C-18 Semi preparative HPLC column 250mm x 20mm x 10u C-18 Analytical HPLC column 250mm x 4.6 mm x 5 u C-8 Analytical HPLC column 250mm x 4.6 mm x 5u i. Branded PC Specification Latest Suitable compatible computer for above system Minimum hardware requirement All PC hardware needs to be listed respectively in the XP Professional hardware compatibility list Microsoft windows compatibility pointing device Pentium 4 processor operating at 1.5GHz or higher with 17 inch flat LCD monitor At least 2 GB RAM for a single instrument 2D or 3D configuration DVD writer Hard disk with at least 500 GB Capacity SVGA or better graphics adaptor and monitor (recommendation resolution 1280 x 1024) true color. LAN Interface with Microsoft TCP/IP protocol installed and LAN card (J4100A jet direct card or G1369A LAN card) for instrument available 82350A/B GP-IB card available with one free IRQ on the PC and one free PCI slot 3 ii. Software Requirement Windows XP Professional SP2 Administrator logon required Temp variable point to an existing dictionary Printer driver is installed on the system Regional setting set to English-US Branded Laser Printer iii.Branded 3 KVA UPS with 30 Min back up. Rated output capacity: 3KV Input voltage:160-270V Input frequency:47-53Hz Battery imput:120V DC Battery type and backup:30 mins Output voltage: 220/230V AC Output frequency: 50.0Hz Inverter Efficiency: Better than 85% Warrantee The instrument should have a 2 Year warrantee for all the parts ( Except consumable spares) GENERAL TERMS AND CONDITIONS 1. The Equipment’s/Machine/Instrument/Glassware/any articles and their makes and grade asked in the Tender will only be accepted. Dealers are requested not to quote any other makes which has been not asked. 2. Dealers have to supply Equipment’s/Machine/Instrument/Glassware/any articles as per the Order (makes and grade mentioned). No alternate makes of Instruments are accepted. And if any dealer supplies any alternate make of Instruments which has not been ordered these Equipment’s/Machine/Instrument/Glassware/any articles will be returned to them at their cost. 3. If the Equipment’s/Machine/Instrument/Glassware/any articles supplied are not found satisfactory, such Instruments will be return to them at their cost. 4. The Order should be complied in totally within fifteen days from date of order or to report how the matter stands. 5. Bills in Triplicate with Pre-stamped receipt/Invoices affixing with Re.1. -Revenue stamp should be sent to us within fifteen days. 4 6. Delivery of Equipment’s/Machine/Instrument/Glassware/any articles are FOR at The Head, Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur. 7. Please note that our Banker is Bank of India, Rashtrasant Tukadoji Maharaj Nagpur University Extension Counter, University Campus, Nagpur-440 033. 8. Outside dealers are requested to negotiate all documents through the above mentioned Bank if applicable. 9. While submitting your quotation kindly mentioned terms and condition clearly regarding i) VAT Tax ii) Sale Tax iii) Octroi iv) Excise Duty and any other tax applicable. 10. Octroi and Excise duty certificate will be provided if the Proforma Invoice and consignment are made on the name of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur. In no case the University will pay the Octroi Tax/Excise Duty. 11. The rates mentioned in the quotations should be valid for six months duration. 12. Blank tender form will be issued after receiving demand draft of any Nationalized/Schedule bank of Rs. 1000/- in favor of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur- 440 033. 13. Earnest Money Deposit (EMD) in the form of demand draft of any Nationalized/Schedule bank of 1% of the cost of items drawn in favor of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur- 440 033 should be submitted in Envelope No. 1. This money (EMD) shall be refunded to the unsuccessful dealer/bidder, within 30 days from the date of the opening of the tenders. No interest shall be paid on earnest money deposited. In case of successful dealer the EMD shall be refunded after the official order and successful installation at Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur 440033 (MS) India. Any offer received without the EMD shall stand wholly rejected. Nevertheless, Decision of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur. (MS) India, on such matters shall remain final and binding. 14. Tender form will not be accepted without paying tender form fee of Rs. 1000/downloaded from web site. 5 15. The supplier shall provide both technical/onsite demonstration /service manual and operation/ installation manual along with the dust cover for the equipment free of cost. 16. The Head, Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur 440033 (MS) India reserves the right to reject lowest of any tender and to increase or decrease the quantity of or split of the items of the tender at any time while finalization of the order. 17. The Head, Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur 440033 (MS) India reserves the right to reject any or all of the tenders without assigning any reasons thereof. 18. In case of any dispute the jurisdiction shall be Nagpur. 19. The tender for equipment/instruments must be sent in sealed envelope with the superscription “Tender for Instruments/equipment for Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur 440033” and addressed to The Head, Department of Pharmaceutical Sciences, RTM Nagpur University Campus, Nagpur 440033 (MS) India. 20. Tenders received late shall not be accepted. All tenders shall be opened in the presence of the bidders or their authenticate representatives in the office of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur in accordance with the date and time specified in the tender notice. 21. No correspondence queries or reminders or personal visits regarding quotation position or ordering action will be entertained or replied. Orders when finalized will be intimated to the parties concerned only. 22. Outside dealers are requested to quote the mode of dispatch of articles, i.e. by Railway, Post Parcel or Goods Transport or Air Mail. 23. You or your representative may be present at the time of opening the quotations. 24. Two bid system (technical and price bid) will be followed. First technical bid will be opened. After the fulfillment of all the necessary documents along with EMD enclosed in technical bid-Part A (i. e. envelope no. 1), then price bid (i. e. envelope no. 2) of the required technical specifications will be only opened. It is, therefore, suggested to submit two independent envelops for technical and financial bids. 25. The details like income tax certificate, VAT registration and clearance, authorization from the manufacturers, previous experience, etc. have to be attached with tender. 6 26. Kindly mention Sales Tax / Registration number of the firm. 27. Advance payment will not be made. 28. The working hours on Saturday are Morning 10:30 AM to 01:30 PM. 29. Equipment’s/Machine/Instrument/Glassware/any articles shall be accepted on any working days up to 05:30 PM. 30. Sale of blank tender form from 02.12.2013 to 23.12.2013. 31. The Last date for the submission of the completed tender is 23.12.2013 up to 05:30 PM. 32. Technical bid (Envelope 1) will be opened on 24.12.2013 at 02:00 PM in the office of The Head, Department of Pharmaceutical Sciences, RTM Nagpur University Campus. The Price Bid (Envelope No. 2) B will be opened on 27.12.2013 at 04:00 PM. 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