18th IAA Humans in Space Symposium (2011) 2059.pdf Conception and Technique of Human Error Management in Space Flight A. P. Nechaev Head of Scientific and Organizing Department, Institute for Biomedical Problems of the Russian Academy of Sciences, Khoroshevskoye Shosse, 76a, 123007 Moscow, Russia Despite measures to prevent human error being undertaken at all stages of manned space objects design and crewmembers training they continue to be observed in the course of crew task performance. The point is that it is very difficult to foresee beforehand all situations which may effect negatively on operator’s reliability. Therefore, working out the methods of human reliability management or, in other words, human error management immediately during space flight is very important. One of reasons of human error is aggravation of his/her psychophysiological state (PPS) under influence of environmental factors. In our previous investigations on basis of the analysis of the data collected during nine “Mir” station missions (18 Russian cosmonauts, 226 flight weeks, 194 crew errors (CE)) the significant (p<0.05) correlation between PPS aggravation and CE frequency has been found. Among the factors affecting PPS we paid special attention to disorders of sleep-wake cycle and surplus workload since these deviations from the nominal work-rest schedule (WRS) of crew are typical for station operation. As a result of data processing the significant (p<0.05) dependence of cosmonaut’s PPS on WRS intensity has been established. It means that WRS intensity may be regarded as “the controlling factor” in respect of cosmonaut’s PPS and – indirectly – of CE. On this basis the method of crewmembers’ PPS management has been developed to reduce CE likelihood. However, large quantity of the parameters used for assessment of cosmonaut’s PPS and WRS intensity posed problems in utilization of this method. As a result of in-depth data analysis the set of these parameters has been reduced and technique of CE management has been simplified. The technique and the algorithm of crewmembers’ errors management are considered in the paper.