Ultrasound in Research Tools and technologies for medical research Who are we? ● Company founded in 2000 Primary goal to build a commercial/clinical ultrasound scanner leveraging PC technology ● Use the x86 platform to rapidly develop and deliver new technologies and provide and provide an openarchitecture tool for research ● ● Develop all: electronics, software, mechanical design Ultrasonix Medical Corporation 2 Traditional Research ● Access limited to “bitmap” images Frame grabbers used to capture analog signals for video images ● ● Lots of equipment required: digitizers, oscilloscopes, etc. ● Analog channel for capturing radio-frequency (RF) signal ● Older scanners were ● ● ● Expensive Large Difficult to work with Ultrasonix Medical Corporation 3 Modern Research ● Digitized data at high sampling rates ● Images in multiple raw formats ● ● ● 8/16 bit grey-scale Doppler data (velocity/direction/power) Strain data ● RF data stream accessed programmatically ● Advantages ● ● ● Greater access Simpler Better quality Ultrasonix Medical Corporation 4 Open Architecture ● ASIC vs Programmable Less expensive long-term Locked to algorithms ● Cannot reprogram ● Faster to end-of-life ● ● Quicker to market – no high up front costs ● Adaptive to new technologies ● Programmable in real-time ● Upgrades to older devices ● Ultrasonix Medical Corporation 5 Open Architecture ● Processing / signal chain ? + Ultrasonix Medical Corporation ! 6 Open Architecture ● Software Programmability Conventional Programmable Sequencing Transmission Ultrasonix Medical Corporation 7 Elastography • Real-time imaging mode for looking at relative stiffness • One of the largest growing research areas in ultrasound • Future of technology – Absolute stiffness – Biopsy reduction Ultrasonix Medical Corporation 8 Virtual Biopsy ● Uses known frequency vibrations to measure tissue stiffness ● Special transducers for enabling vibrations Ultrasonix Medical Corporation 9 Spatial Tracking Needle Guidance Using EM sensing to guide user Taking out the Guesswork - Less chance to redo insertion - Less risk for infection Ultrasonix Medical Corporation 10 Fusion Systems Combination of ultrasound registered to MR/CT/PET ● Ultrasonix Medical Corporation 11 Vascular Measurements Makes use of sequencing and transmit control to enhance the way blood flow measurements are made ● Ultrasonix Medical Corporation 12 Other Applications ● Beamforming / signal processing algorithms ● Transducer prototyping ● Ablation or HIFU guidance ● Contrast agents ● Photoacoustics Ultrasonix Medical Corporation 13 Open Platform Composition • Internal parameter control • Access to data – Post Scan – Real-time • • • • Control of transmit Control of beam sequencing Transducer neutral Software toolkits Ultrasonix Medical Corporation 14