Canine and Feline Infections
Disease Prevention VI
Parasites
ANS 424
N. Matthew Ellinwood, D.V.M., Ph.D.
February 1, 2012
IOWA STATE UNIVERSITY
COLLEGE OF AGRICULTURE AND LIFE SCIENCES
Parasites and Vector Borne Disease
• Emphasis on control and prevention
• Ectoparasites
– Ticks and fleas
• Arthropod borne disease
– Heartworm
• Intestinal parasitism
Ectoparasite Control
• Products
• Frontline Plus
– Fipronil and S-methoprene
• GABA gated chloride channel blocker - stimulant
• Juvenile hormone anologue (fatty acid derivative)
– Active against (Fipronil)
• Adult flees, dear tick, brown dog tick, American dog
tick, and lone star tick
– Active against (S-methoprene)
• Flee eggs and larva
– Different cat and dog product
Additional Products
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•
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Advantix II
Kills and repels
Fleas, ticks, and mosquitoes (all stages)
Neurotransmitter disrupters/neurotoxins:
– Imidacloprid and permethrin
• Growth regulator disrupter
– Pyripoxyfen – disrupts egg hatching
• Not a cat product
– Restrict contact between cats and dogs, 24 hrs post admin
Additional Products
•
•
•
•
Advantage II
Kills
Fleas, ticks, and mosquitoes (all stages)
Neurotransmitter disrupters/neurotoxins:
– Imidacloprid
• Growth regulator disrupter
– Pyripoxyfen – disrupts egg hatching
• Cat and dog products
Ectoparasite Borne Diseases
• Lyme disease
– Deer tick
• Dipylidium caninum (one of three tape worms)
– Flea ingestion
• Hemobartonellosis, anoplasmosis, Rocky
mountain spotted fever, rickettsial, ehrilichial
agents, etc.
– Fleas or tick vectors
Heartworm Prevention
• Vector borne microfilarial parasite
– Mosquito
– Adults cause life threatening chronic lung and
heart disease in dogs
– Incidence of clinical disease in cats unclear but
is likely 1/10th that of canine disease
– http://www.heartwormsociety.org/
– Chemoprophylaxis
Heartworm Prevention
• Topical/Oral
• Oral
– Ivermectin (heart guard) or Milbemycin
(interceptor) based
• Topical
– Moxidectin (Advantatge Multi for cats or dogs)
– Selamectin (Revolution for cats or dogs)
Intestinal Parasites
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•
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Round worm
Hook worm
Whip worm
Adult versus reproductive/neonatal infection
• Rountine prevention
– Whip worm (reinfestation) and Hook worm