AbstractID: 12035 Title: Clinical implementation of respiration motion correlated imaging, treatment planning and delivery Respiratory motion is a significant factor in determining a suitable planning target volume (PTV) that surrounds the demonstrable gross tumor volume (GTV) in the radiotherapy of mobile lesions. Historically, a “one-size-fits-all” margin derived from population statistics has been employed to account for such motion. The advent of respiratory phase correlation (4D) and multi-slice CT technology has enabled patient-specific determination of both demonstrable tumor volume and its motion from a single imaging study. Management of such additional information during treatment planning and delivery however presents several challenges. Furthermore, guidelines for establishing clinical treatment planning and delivery protocols based on respiratory correlated imaging data differ from one institution to the other. The purpose of this presentation is to educate the community on the different respiratory correlated radiotherapy approaches currently available and compare the benefits and pitfalls in each case. Special focus will be on treatment planning, dose calculation and treatment delivery related issues. After the course, the attendees should be able to: 1) Understand the different respiratory correlated treatment planning and delivery approaches 2) Compare the benefits and pitfalls of each of the above approaches 3) Develop and establish respiratory correlated imaging, treatment planning and delivery appropriate to the available equipment