Introduction (Doses & risks) Adult & pediatric doses in CT CT doses (CTDI/E) Walter Huda PhD Head CT doses SUNY Upstate Medical University, Syracuse NY Reducing CT doses Cataracts Deterministic effect x-ray skin dose 2 mGy/0.2 rad CT skin dose 40 mGy/4 rad Carcinogenesis Stochastic effect 1 Dose distributions in CT measured in phantoms Computed Tomography Dose Index (CTDI) Contiguous CT imaging CTDI = 1/h ∫ D(z) dz 16 cm and 32 cm diameter Acrylic phantoms ρ= 1.19 Z = 6.56 2 Helical scanning & dose Pitch of 1.0 has dose ≈ axial scan Pitch of 0.75 has 33% more dose Pitch of 1.5 has 66% less dose 3 Dose (risk) in CT is best measured by effective dose (E) CTDI is independent of section thickness T & number of sections N Patient risk does depend on section thickness T & number of sections N E = Σi wi x Di 127 patients undergoing head CT examinations Computing adult and pediatric doses in head CT examinations Measurements made at level of the basal ganglia Dimensions & average HU 100 Heads modeled as water equivalent cylinders with a radius r 90 Radius (mm) 300 250 80 70 60 200 0 5 10 15 20 Patient age (Yr) 150 120 Infants ~60 mm 110 100 100 Radius (mm) Mean HU 50 50 Adults ~90 mm 90 80 70 0 0 20 40 60 80 100 60 20 Patient age (Yr) 40 60 80 100 Patient age (Yr) 1 CTDI is equal to: Energy imparted/Section mass “CTDI” for any sized radius (Energy imparted/Section mass) Monte Carlo modeling Radiology (1997) 203:417-422 Energy imparted 70 0 - 6 months 60 340 mAs “CTDI” x Directly irradiated mass (i.e., π⋅r π⋅ 2⋅T⋅⋅N) CTDI (mGy) 50 40 30 20 Adults 10 0 70 80 90 100 110 120 130 140 150 kVp For an anthropomorphic phantom & head CT scan, compute : 180 Adults Energy imparted (mJ) 160 340 mAs 140 120 100 Effective dose E Energy imparted ε E/ε ratio 80 60 40 0 - 6 months 20 0 70 80 90 100 110 120 130 140 150 kVp 2 Effective dose per unit energy imparted for head x-ray examinations vs size Effective dose per unit energy -1 imparted (E/ε mSv J ) Compute E/ε ratio for different sized patients (i.e., newborn to adults) 10 1 10 Patient age (year) 9 Chest CT 5 0 - 6 months 340 mAs 4 7 Effective dose (mSv) Effective dose (mSv) 8 3 2 Adults 6 5 4 1 3 0 r ² = 0.465 70 80 90 100 110 120 130 140 150 kVp 2 40 50 60 70 80 90 Weight (kg) Patient dose: is proportional to mAs Doses from CT are a major concern increases by factor of 5 when going from 80 to 140 kV (@ constant mAs) 3 Frequency of CT examinations Germany 1994 CT contribution to collective medical dose Germany 1994 4 Dose reduction strategies Tube current modulation for non-circular cross-sections of the body Technology (AEC) Dose reduction (ALARA) Optimization GE Smart mA (LightSpeed Ultra) High dose scan Low dose scan 120 kVp 5 mm 120 kVp 43mAs 5 mm 206 mAs A Metastasis in vertebral body B Subcutaneous gluteal metastatis C Small gas inclusion D ureter opacified c contrast 1 Increasing the x-ray photon energy (kVp) reduces image contrast Optimizing CT with respect to dose Muscle Relative HU 1.0 0.5 Iodine 0.0 50 55 60 65 70 75 80 Photon Energy (keV) The mAs used to make a CT image is very important Contrast to noise ratio (CNR) defines CT image quality. Low CNR High CNR 2 First CT image (120 kVp) 100 Noise (HU) 32 cm CT CNR can be changed via mAs; CT is quantum noise limited 10 16 cm 1 40 60 80 100 200 Relative energy imparted Constant CNR at each kVp Iodine 4 3 2 1 Soft tissue 80 100 120 140 X-ray tube voltage (kVp) 400 mAs Stochastic risks are important in CT Deterministic risk should not occur Effective doses in CT 1 – 2 mSv for head 5 – 10 mSv for body CT doses “dominate” medical exposures ALARA principle should be used to minimize patient doses 3