PET Shielding Is Complex PET/CT Shielding Evaluation • More lead is used than for typical radiographic installations • The safety factor is much less than for most diagnostic Installations • Exposure usually occurs from multiple sources G. Donald Frey, Ph.D. Department of Radiology Medical University of South Carolina Charleston, SC 1 2 3 4 5 6 1 Shielding Evaluation My Priorities • To Insure • Check for proper construction • Determine the adequacy of the shielding • NCRP 147 Radiation Doses are below the levels required by regulation Are consistent with the shielding design That the shielding is properly installed 7 Instrumentation 8 Instrument of Choice • We have used three types of instruments • All three devices gave approximately equal readings • All could produce accurate measurements • The portable NaI(Tl) survey meter was somewhat more sensitive and convenient to use Large volume ionization chamber • Radcal 9010 w/ 10X5-1800 Portable pressurized ionization chamber • Innovision 451P Portable NaI(Tl) Survey Meter • Exploranium GR-135 9 10 Evaluating the Annual Exposure at a Location Proper Construction • Use source in each location • Use meter to scan for gaps and voids 11 12 2 Scaled Source Method • Find scaled source strengths that give the same radiation exposure (air kerma) as the total activity that is used in the room • Place sources in all patient locations • Measure dose at appropriate Annual Dose = Dose Rate x Number of Patients x Time Each Patient is in the Room 13 Source 14 Activity = Average Patient Dose x Number of Patients x Time Each Patient is in the Room Source Source = Annual Dose = Dose Rate x 1 hour 15 16 Average Patient Activity Uptake Room Or ANτ R A = D Hx, y, zL = D Nτ • Factors A 17 Administered activity Time patient spends in room Number of patients in the room Patient self attenuation factor 18 3 Average Patient Activity Uptake Room Au = ζ A0 ‡ τu H 1 ê 2 L t ê T 1 ê2 t A u = ζ H A 0 ê ln H2 LL HT 1 ê2 ê τ u L H1 − H1 ê 2 L 0 Annual Dose Uptake Room H τ u ê T 1 ê2 L Au D ui Hx, y, z L A u N ui τ u D ui Hx, y, z L N ui τ u L D ui Hx, y, z L 19 20 Average Patient Activity Scan Room Average Patient Activity Scan Room • Factors A s = ζ A 0 H 1 ê 2 L H τ u ê T 1 ê2 L κ ‡ Administered activity Time patient spends in uptake room Fraction of activity voided by patient Time patient spends in scan room Number of patients in the room Patient self attenuation factor τs A s = ζ H A 0 ê ln H2 LL H1 ê 2 L x H 1 − H 1 ê 2 L H τ s ê T 1 ê2 L L 0 H 1 ê 2 L t ê T 1 ê2 H τ u ê T 1 ê2 L κ HT 1 ê2 ê τ s L 21 22 Annual Dose Scan Room As D si Hx, y, z L A s N si τ u D si Hx, y, z L N si τ s t Dose from All Rooms D si Hx, y, z L 23 ‚ As Nsi τu + ‚ Au Nui τu i D Hx, y, zL i 24 4 So from all rooms Scaling Factor So we need to Scale the Activity 500 mCi Effective Scaled Activity Activity 20536 41 5134 10 9001 18 Room Uptake Room 1 Uptake Room 2 Scan Room i y j zìσ j j‚ As Nsi τu + ‚ Au Nui τuz z i ki { D Hx, y, zL ê σ αui = Au Nui τu ê σ αsi = As Nsi τs ê σ 25 26 Compare Results to Design Values So from all rooms Scaling Factor Room Uptake Room 1 Uptake Room 2 Scan Room p ê TD Hx, y, zL b 1 500 mCi Effective Scaled Activity Activity 20536 41 5134 10 9001 18 • Correct for Occupancy Factors • Correct for decay of sources during the measurement 27 28 Inside Source Size Calculation Facility Date Administered Activity Half Life of Radionuclide Self Absorption Factor Medical University of South Carolina PET/CT Facility Location Control Room Operator Control Room Secondary Operator Door to Corridor Entrance Corridor Corridor Door to Uptake Room Corridor Door to Uptake Room Outside Porch 1/9/2006 555 MBq 110 min Inside 15 mCi 0.72 Room Time between injection and beginning of room use Decay Factor Time patient remains in room Decay Dose Rate Factor Voiding Factor (Retention when patient enter room) Patients per week Effective Activity Uptake Room 1 0 min 1 90 0.76 1 32 759826 MBq 20536 mCi 29 Distance Design Limit Annual Limit Design Value (P) 5 5 5 5 5 50 5 Me ter Time Annual Time Rea ding Corrected Estimate 8:43 AM 2.30 1.42 0.71 8:45 5.30 3.30 1.65 8:45 4.60 2.87 1.43 8:47 8.90 5.62 2.81 8:48 30.00 19.06 9.53 8:48 30.00 19.06 9.53 8:49 14.10 9.01 4.51 Loca tion Control Room Operator Control Room Secondary Operator Door to Corridor Entrance Corridor Corridor Door to Uptake Room Corridor Door to Uptake Room Outside Porch Time Annual Corrected Estimate 1.42 0.71 3.30 1.65 2.87 1.43 5.62 2.81 19.06 9.53 19.06 9.53 9.01 4.51 Percent P-Value 14% 33% 29% 56% 191% 19% 90% Status Pass Pass Pass Pass Fail Pass Pass Distance Design Limit Annual Limit Percent P-Value 14% 33% 29% 56% 191% 19% 90% Status Pass Pass Pass Pass Fail Pass Pass Occupa ncy Annual Factor Estimate 1.00 0.71 1.00 1.65 1.00 1.43 1.00 2.81 1.00 9.53 1.00 9.53 1.00 4.51 Design Value (P) 5 5 5 5 5 50 5 Occupancy Annual Factor Estimate 1.00 0.71 1.00 1.65 1.00 1.43 1.00 2.81 1.00 9.53 1.00 9.53 1.00 4.51 Percent P-Value 14% 33% 29% 56% 191% 19% 90% Status Pass Pass Pass Pass Fail Pass Pass Meter Time Reading 8:43 AM 2.30 8:45 5.30 8:45 4.60 8:47 8.90 8:48 30.00 8:48 30.00 8:49 14.10 Percent P-Value 14% 33% 29% 56% 191% 19% 90% Status Pass Pass Pass Pass Fail Pass Pass 30 5 Evaluating Lead in Wall • • • • • Use a source in room Measure air kerma at point outside wall Determine B Evaluate using chart from TG 108 Calculate Using Archer Equation 31 32 Direct Calculation How Much Activity Do You Need? 100000 • The thickness can also be calculated using the model of Archer et al 10000 Required MBq x = H1 ê αγ L ln 8@B −γ + Hβ ê α LD ê @1 + Hβ ê α LD< D c = A0 G ê d2 B = Dm d2 ê A0 G x = H1 ê αγ L ln −γ 8@HD m d 2 ê A 0 Γ L + Hβ ê α LD ê @1 + Hβ ê α LD< 1000 100 0 33 Desired distance Desire Air KERMA US Inches 0 1/16 1/8 1/4 3/8 1/2 3/4 1 Metric mm 0 1.6 3.2 6.4 9.5 12.7 19.1 25.4 5 10 15 Lead (mm) 20 25 30 34 3 mete rs 10 uSv/hr Attenuation 1.000 0.829 0.674 0.430 0.267 0.164 0.062 0.023 Activity Unshielded MBq uSv/hr 629 10 759 12 933 15 1465 23 2357 37 3826 61 10168 162 27078 430 35 36 6 Lead T hickness Evaluation F-18 Source Calibration Time Gamma Constant Alpha Beta Gamma Barrier 1742.7 3:35 PM 0.143 1.5430 -0.4408 2.1360 None Uptake 1 (Rear) Uptake 1 (Rear) uSv-m2/MBq-h per cm per cm Unshielded Measured Measured NET Calculated Activity Distance Air Kerma Bkg Air Kerma Air Kerma MBq m uGy/hr nGy/hr uGy/hr uGy/hr 3:50 PM 1586 3.0 25.5 110 25.39 24 3:58 PM 1508 3.0 5.3 110 5.19 23 4:04 PM 1452 1.5 19 110 18.89 89 Time Symbols MBq B 1.04 0.22 0.21 Calculated Specified Lead Lead Deviation mm mm -0.4 0 10.7 10 7% 11.1 10 11% A0 = Administered Activity Au = Average activity per patient in the uptake room As = Average activity per patient in the scan room T1ê2 = Physical Half − life for F − 18 τu = time patient waits after injection τs = time it takes to complete the PET ê CT exam κ = fraction of the administered activity the patient voids ζ = self absorption factor N = total patients per year Nui = number of patients per year in uptake room i Nsi = number of patients per year in scan room i N = ‚ Nsi = ‚ Nui i i 37 38 39 40 Dui Hx, y, zL = The average dose rate at any location Hx, y, zL from a patient in uptake room 1 Dsi Hx, y, zL = The average dose rate at any location Hx, y, zL from a patient in scan room 1 Dui Hx, y, zL = the annual dose to any location Hx, y, zL from all of the patients in uptake room i Dsi Hx, y, zL = the annual dose to any location Hx, y, zL from all of the patients in scan room i D Hx, y, zL = the annual dose to any location Hx, y, zL from all the patients in the facility σ = the dose scaling parameter αui = the scalled activity for uptake room i αsi = the scalled activity for scan room i p = design value Hp = 1 mSv ê yr for non − controlled areas, 5 mSv for controlled areas L T = occupancy factor 7