M. S. RAMAIAH INSTITUTE OF TECHNOLOGY BANGALORE-54 (Autonomous Institute, Affiliated to VTU) Outcome Based Education Curricula (For 2012-2013 Admission Batch) Academic year 2015-2016 emester B. E. mester B. E. VII & VIII SEMESTER MEDICAL ELECTRONICS 1 History of the Institute: M. S. Ramaiah Institute of Technology was started in 1962 by the late Dr. M.S. Ramaiah, our Founder Chairman who was a renowned visionary, philanthropist, and a pioneer in creating several landmark infrastructure projects in India. Noticing the shortage of talented engineering professionals required to build a modern India, Dr. M.S. Ramaiah envisioned MSRIT as an institute of excellence imparting quality and affordable education. Part of Gokula Education Foundation, MSRIT has grown over the years with significant contributions from various professionals in different capacities, ably led by Dr. M.S. Ramaiah himself, whose personal commitment has seen the institution through its formative years. Today, MSRIT stands tall as one of India’s finest names in Engineering Education and has produced around 35,000 engineering professionals who occupy responsible positions across the globe. About the Medical Electronics Department The Medical Electronics department at M.S. Ramaiah Institute of Technology (MSRIT), Bangalore was started in the year 1996. The department is offering 4-year full time B. E. degree course in Medical Electronics, affiliated to VTU, Belgaum, recognized by Government of Karnataka, approved by AICTE, New Delhi and accredited by NBA. The department is located at Lecture Hall Complex of MSRIT Campus. The department consists of a highly motivated & qualified faculty and dedicated supporting staff headed by Dr. N. Sriraam, Academy-industry experienced Professor with specialization in biomedical signal processing. 2 Faculty List Sl.No Names of Faculty Qualification Designation 1 Dr. N Sriraam B.E., M.Tech, Ph.D Professor and Head 2 Prof. P G Kumaravelu B.E., M.Tech Professor 3 Dr. C K Narayanappa Mrs. Prabhu Ravikala Vittal Mrs. Uma Arun B.E., M.Tech, Ph.D Associate Professor 4 5 6 B.E., ME, (Ph.D) Associate Professor B.E, M.S., (Ph.D) Assistant Professor Assistant Professor 7 Mr. S J Mahendra B.E., M.Sc, MBA, (Ph.D) B.E., M.Tech,(Ph.D) 8 Mrs. Purnima B R B.E., (M.Sc (Engg.)) Assistant Professor 9 Ms. Supriya Babu BE, M.Sc Assistant Professor 10 Mr.Sanjay H S B.E., M.Tech,(Ph.D) Assistant Professor 11 Mr. Basavaraj V Hiremath B.E., M.Tech, (Ph.D) Assistant Professor 12 Mrs.Chandana S B.E, M.Tech, (Ph.D) Assistant Professor Mrs. Prabha Ravi Assistant Professor Vision and Mission of the Institute and the Department The Vision of MSRIT To evolve into an autonomous institution of international standing for imparting quality technical education The Mission of the institute in pursuance of its Vision: MSRIT shall deliver global quality technical education by nurturing a conducive learning environment for a better tomorrow through continuous improvement and customization Quality Policy “We at M. S. Ramaiah Institute of Technology, Bangalore strive to deliver comprehensive, continually enhanced, global quality technical and management education through an established Quality Management system Complemented by the Synergistic interaction of the stake holders concerned”. 3 Vision of the Department: “Provide quality education, motivational academic environment and foster strong academic-industrial ties to empower the students to face the challenges of tomorrow” Mission of the Department: The department shall transform the entrant of the program into professionally competent engineers through innovative curricula, research, practical training and effective collaboration with industry, hospital, and academia. Process of deriving the vision and mission of the department Process of deriving the vision and mission of the department is shown in Figure below Institute’s Vision & Mission Management Vision & Mission of the Department by the committee Parents Industry Alumni Department Faculty Students Periodic Review 4 5 Process of Deriving the PEOs of the programme Department Vision & Mission Institute Vision & Mission Committee formation and preparation of questionnaire Conduction of Survey Students Parents Alumni Industry Collect data (Department Committee) Deliberate, Analyze and summarize the data (Board of Studies) Academic Council & Governing Council Accept & Approve PEOs 6 PG faculty Programme Educational Objectives (PEOs) 1. Solve the real-life healthcare problems by employing the knowledge and skills of Medical Electronics 2. To bridge the gap between engineering and medicine by optimal design & implementation of healthcare technologies 3. To inculcate professional and ethical values in lifelong learning process Process of deriving the Programme Outcomes The Programme outcomes are defined taking into account the feedback received from faculty, alumni, Industry and also from guidelines put across by regulatory/professional bodies and graduate attributes which are in line with programme educational objectives. The following Fig. 2.1 indicates the information flow. Department Vision and Mission Institute Vision and Mission Feedback Faculty Programme Educational Objectives Student Graduate Attributes Regulatory bodies such Programme Outcomes as UGC,AICTE,VTU Alumni Professional bodies such as IIIE, NITIE of Deriving the PEOs of the programme Indu Process stry 7 Program Outcomes The graduates of the programme will be able to: a. Apply knowledge and skills of mathematics, engineering and science to various healthcare domains. b. Design and conduct experiments, as well as analyze and interpret data. c. Design and improve a system, component or a process to meet desired needs within realistic constraints such as economic, social, health, ethical and safety, manufacturability and sustainability. d. Function as a member, of a multi-disciplinary team. e. Identify, formulate and solve engineering problems. f. Understand and respect professional and ethical responsibility. g. Communicate effectively both orally and in writing. h. Understand the impact of engineering solutions in a global and societal context. i. Recognize the need for and an ability to engage in life-long learning. j. Have knowledge of contemporary issues in healthcare and service sectors. k. Use updated techniques, skills and tools necessary for engineering practices throughout their professional careers. l. Implement the concepts of project and financial management to satisfy customer expectations. Program Objectives • After graduation a medical electronics engineer will be capable of: ▫ Being employed in any of the wide ranging careers in healthcare related positions in industry, hospitals, research institutions or academia. ▫ Pursuing advanced degrees in biomedical engineering, Bioengineering or other fields related to their long term career goals 8 Mapping of PEO’s and PO’s The correlation between the Programme outcomes and Program Educational objectives are mapped in the Table shown below: Correlation between the POs and the PEOs Sl. No. Programme Outcomes Programme Educational Objectives a b c 1 Solve the real-life healthcare problems by employing the knowledge and skills of Medical Electronics X X X 2 To bridge the gap between engineering and medicine by optimal design & implementation of healthcare technologies X 3 To inculcate professional and ethical values in lifelong learning process d e f X g h i X X X X j k l X X X X X X X X X X X X Curriculum breakdown structure: The curriculum of Medical Electronics programme is so structured to include all the courses that together satisfy the requirements of the programme specific criteria. The Course code, Course title, the number of contact hours and the number of credits for each course are given in the following table. The courses are grouped in line with the major components of the curriculum namely: (i) Mathematics and Basic sciences, (ii) Basic Engineering courses, (iii) Humanities and Social Sciences, (iv) Professional core courses, (v) Electives and (vi) industry/hospital exposure/internship. 9 Breakup of Credits for BE Degree Curriculum. (I to VIII Semester) Sem HSS BS ES PCS Professional Electives Other Electives Project / Seminar/ Internship Total Credits II 06 20 24 III -- 04 -- 22 - - - IV - 04 - 21 - - - V 03 - - 23 -- - - VI 04 - - 18 03 - 01 VII - - - 08 09 03 05 VIII 07 - - -- - 15 22 Total 20 28 24 92 03 21 200 I 50 12 HSS - Humanities and Social Sciences BS - Basic Sciences (Mathematics, Physics, Chemistry) ES - Engineering Sciences (Materials, Workshop, Drawing, Computers). PCS - Professional Core Subjects Prof. Ele - Professional Electives, relevant to the chosen specialization branch. Other Ele - Elective Subjects, from other technical and / or emerging subject Areas. Project / Seminar - Project Work, Seminar and / or Internship in industry or elsewhere. 10 26 25 26 26 25 - - 13 28 24 98 19 03 15 BOARD OF STUDIES MEMBERS M.S. RAMAIAH INSTITUTE OF TECHNOLOGY, BENGALURU-54 (Autonomous Institute, Affiliated to VTU) ANNEXURE – III BOARD OF STUDIES - Department of Medical Electronics (TO BE CONSTITUTED AS OER 5.3 OF STATUTE FRAMED SECTION 43(A) OF 2006 AMENDED) VTU ACT 1994. Sl.No 1. 2. 3. CATEGARY HEAD OF THE DEPARTMENT CONSERNED AT LEAST 5 FACULTY MEMBERS AT DIFFERENT LEVELS COVERING DIFFERENT SPECIALISATIONS, TO BE NOMINATED BY THE ACADEMIC COUNCIL TWO EXPERTS IN THE SUBJECT FROM OUT SIDE THE COLLEGE, TO BE NOMINATED BY THE ACADEMIC COUNCIL. NAME OF THE PERSON WITH OFFICIAL ADDRESS DR. N. SRIRAAM PROF. & H.O.D. DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T. BENGALURU-54 Prof. P.G. KUMARAVELU PROFESSOR, DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T- BENGALURU-54 MRS. PRABHU RAVIKALA VITTAL ASSOCIATE PROFESSOR DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T- BENGALURU-54 MRS. UMA ARUN ASSISTANT PROFESSOR DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T- BENGALURU-54 MRS. PRABHA RAVI ASSISTANT PROFESSOR DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T- BENGALURU-54 MRS. SUPRIYA BABU ASSISTANT PROFESSOR DEPT. OF MEDICAL ELECTRONICS M.S.R.I.T- BENGALURU-54 DR. VENKATESH BALASUBRAMANIAN ASSOCIATE PROFESSOR , ENGINEERING DESIGN DEPT. IIT CHENNAI MR. RAVI BHARADWAJ ENGINEERING MANAGER INDIA GE HEALTHCARE JOHN F WELEH TECHNOLOGY CENTER BANGALORE 11 STATUS CHAIRPERSON MEMBER MEMBER 4 ONE EXPERT FROM OUTSIDE THE COLLEGE, TO BE NOMINATED BY THE VICE CHANCELLOR FROM A PANEL OF SIX RECOMMENDED BY THE PRINCIPAL ONE REPRESENTATIVE FROM INDUSTRY /CORPORATE AREA SECTOR/ALLIED / RELATING TO PLACEMENT, TO BE NOMINATED BY THE ACADEMIC COUNCIL. ONE POST GRADUATE MERITORIOUS ALUMNUS, TO BE NOMINATED BY THE PRINCIPAL 5. 6. DR. MALLIKARJUN. S. HOLI PROF. & H.O.D. DEPT. OF BIO-MEDICAL ENGG., UNIVERSITY BDT COLLEGE OF ENGINEERING. DAVANAGERE577004 MR. RAVINDRAN DIRECTOR AND CTO SKANRAY HEALTHCARE PVT. LIMITED PLOT NO. 360, KIADB INDUSTRIAL AREA, HEBBAL , MYSORE -570 018 MRS. PADMAJA KANKIPATI, PhD DIRECTOR OF SERVICE DELIVERY & R & D SPECIALIZED MOBILITY OPERATIONS AND INNOVATIONS, 2ND FLOOR, SONA TOWERS, 71 MILLERS ROAD, BANGALORE -560 052 SPECIIAL INVITEES-EXPERT Sl.No 1. 2. NAME OF THE PERSON WITH OFFICIAL ADDRESS DR. RAVI RAMASWAMY SR. DIRECTOR & HEAD-HEALTH SYSTEMS PHILIPS INNOVATION CAMPUS MANYATA TECH PARK, BANGALORE 560045 DR. SHYAM VASUDEVA RAO PRESIDENT & CTO FORUS HEALTH PVT. LTD. 4085A,2ND FLOOR, K R ROAD, BSK II STAGE, BANGALORE – 560 082. 12 STATUS Special Invitee Special Invitee MEMBER MEMBER MEMBER M. S. RAMAIAH INSTITUTE OF TECHNOLOGY, BANGALORE (Autonomous Institute, Affiliated to VTU) SCHEME OF TEACHING FOR THE ACADEMIC YEAR 2015-2016 VII SEMESTER B. E. MEDICAL ELECTRONICS Sl. Subject No. Code 1 2 3 4 5 6 7 8 9 ML701 ML702 ML703 Credits Subject Teaching Dept. Neural networks and Medical Electronics Its Applications Engineering Medical Imaging Medical Electronics Systems Engineering Project-Phase I Medical Electronics Engineering ML704 Hospital Training Medical Electronics Engineering MLL705 Application Lab Medical Electronics Engineering MLPE3X Elective-I Medical Electronics Engineering MLPE4X Elective-II Medical Electronics Engineering MLPE5X Elective-III Medical Electronics Engineering OE Open Elective Medical Electronics Engineering Total *L: Lecture *T: Tutorial 13 Contact TOTA Hours/ L Week 0 4 4 0 0 4 4 0 1 1 2 4 0 1 1 2 - 0 0 1 1 2 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 20 2 3 25 - L* T* P* 4 0 4 *P: Practical ELECTIVE III Sl. Subject No. Code ML PE31 1 Contact Credits Subject Teaching Dept. Computer Medical Electronics Communication Engineering Hours/ L* T* P* Total 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 Week Networks 2 3 4 ML PE32 ML PE33 ML PE34 ML PE35 5 Medical Device Medical Electronics Regulation Engineering Medical Electronics Medical Electronics Design Engineering Human Assist Medical Electronics Devices Engineering Ergonomics & Medical Electronics Rehabilitation Engineering Engineering 6 ML PE36 VLSI Design Medical Electronics Engineering ELECTIVE- IV Sl. Subject No. Code MLPE41 1 Contact Credits Subject Teaching Dept. Advanced Medical Medical Electronics Instrumentation Engineering Hours/ L* T* P* Total 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 Week Technology 2 3 4 5 6 MLPE42 Telemedicine Medical Electronics Engineering MLPE43 Biogrid Computing Medical Electronics Engineering MLPE44 MLPE45 MLPE46 Physiological Medical Electronics System Modeling Engineering Biomedical Medical Electronics Nanotechnology Engineering Pattern Recognition Medical Electronics Engineering 14 ELECTIVE- V Sl. N o. 1 2 3 4 5 6 Subject Code MLPE51 MLPE52 Teaching Dept. Data mining and Medical Electronics medical applications Engineering Clinical Engineering Medical Electronics Engineering MLPE53 MLPE54 MLPE55 MLPE56 Contact Credits Subject Introduction to Cloud Medical Electronics Computing Engineering Pharmacology and Medical Electronics Drug Delivery Engineering Hospital Medical Electronics Management Engineering Digital Video Medical Electronics Processing Engineering Hours/ L* T* P* Total 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 3 0 0 3 3 Week OPEN ELECTIVE Sl. Subject No. Code 1 2 3 MLOE01 MLOE02 MLOE03 Contact Credits Subject Teaching Dept. Hours/ L* Medical Medical Electronics Instrumentation Engineering Hospital Medical Electronics Management Engineering Biomechanics Medical Electronics Engineering 15 3 3 3 T* P* 0 0 0 0 0 0 Total Week 3 3 3 3 3 3 VIII SEMESTER B. E. MEDICAL ELECTRONICS Sl. Subject No. Code 1 2 3 ML801 Subject Intellectual Property Rights & Medical Ethics ML802 ML803 Management & Teaching Dept. Medical Electronics Engineering Medical Electronics Entrepreneurship Engineering Project-Phase II Medical Electronics Engineering ML804 Internship Medical Electronics Engineering Total *L: Lecture Contact Credits *T: Tutorial 16 Hours/ L* T* P* TOTAL 3 0 0 3 3 4 0 0 4 4 0 0 14 14 -- 0 0 1 1 -- 7 0 15 22 *P: Practical Week NEURAL NETWORKS AND ITS APPLICATION Subcode: ML701 Credits: 4:0:0 Prerequisite: Nil Contact Hours: 56 Course Coordinator(s): Dr.N.Sriraam, Mrs.Prabha Ravi Course objectives: 1. To understand the difference between biological neural network and artificial neural network 2. To study various neural network architecture and algorithms 3. To analyze the suitability of various neural network model for various applications 4. To apply the models for clinical diagnostic applications Course contents: UNIT I Overview of neural networks: Elementary neurophysiology and biological neural network- typical applicationsmodels of a neuron- typical architecture- activation functions -Mcculloch Pitts neuron model.- Learning rules:Hebbian, Perceptron, Delta, Competitive, Oustar,Boltzmann Simple neural nets for pattern classification: Biases and Thresholds, Linear Separability- Hebb net-perceptron, Adaline and Madaline. UNIT II Pattern association: Training Algorithms for Pattern Association Heteroassociative Memory Neural Network, Autoassociative Net, Iterative Autoassociative Net, Bidirectional Associative Memory (BAM) UNIT III Backpropagation neural net: Backpropagation Architecture and Algorithm- Weight Update Procedures, Learning Rules UNIT IV Neural networks based on competition: Fixed-Weight Competitive Nets, Kohonen Self-Organizing Maps, Learning Vector Quantization, Counter propagation UNIT V Adaptive resonance theory: Basic Architecture and Operations- ART1: architecture-algorithm-applicationsART2 :architecture-algorithm-applications All networks will be demonstrated using MATLAB/SCILAB Text books: 1. Laurene Fausett,”Fundamentals Of Neural Networks , Pearson, 2013 2. J.A. Freeman & David.M. Skapura, Neural networks, Algorithms applications and programming techniques, Addison Wesley, 1991. ISE Reprint 1999. Reference Books: 1. David M. Skapura, “Building Neural Networks”, Addison Wesley, 1996. 2. Bose, “Neural Network Fundamentals with graphs, algorithms and applications”, Tata McGraw-Hill, 1995 3. Simon Haykins, “Neural Networks”, Pearson Education Asia, Third Edition, 2009 4. S.N.Sivanandam, Sumathi, Deepa “An Introduction to Neural Networks using MATLAB”. Tata McGraw Hill 2006 17 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: The students should be able to: On completion of this course, the students will get insight on 1. Fundamental knowledge on biological neural network and artificial neural network (pos: a.k) 2. Understanding various neural network models and its implementation (pos: b,k) 3. Application of suitable neural network for clinical diagnosis (pos:5) Assessment and Evaluation vis-à-vis Course Outcomes: Direct Assessment Methods What Frequency Max Marks 30 Thrice (Average of the best two will be computed) Once/twice Internal assessment tests CIE Group activities/Surprise test/ MCQS/Quiz/others SEE Indirect Assessment Methods To whom Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 test answer scripts 1, 2 and 4 Answer scripts 1, 2 and 3 10 Twice (Average will be computed) End of course (Answer any 5 of 10 questions) Middle of the course 10 100 - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%) : Bloom Level T1 T2 T3 O THERS Remember Understand Apply Analysis Evaluate Create 10 40 30 20 - 10 40 30 10 10 - 10 30 20 20 10 10 20 60 10 10 - 18 30 30 20 20 - SEE 10 40 15 15 10 10 MEDICAL IMAGING SYSTEMS Subcode: ML702 Prerequisite: Nil Course Coordinator(s): Mrs.Prabha Ravi, Mr.Sanjay H S Credits: 4:0:0 Contact Hours: 56 Course objectives: 1) To enable students to develop a basic familiarity with all the major medical imaging techniques employed in modern hospitals, including x-ray imaging, computer tomography, magnetic resonance imaging, ultrasound, nuclear isotope imaging, and electroencephalography. 2) Each technique will be introduced in the context of the underlying clinical requirements. 3) Students need to learn what physical principles are involved, and what properties of tissues the corresponding medical images show. 4) The module will aim to develop an understanding of the historical evolution of these imaging methods, as well as indicate how medical imaging is likely to develop over the next few years. Course contents: UNIT - I Radiography : Fundamentals of x-rays, Generation and Detection of x-rays, X-ray Diagnostic method, Recent developments, x-ray image characteristics, biological effects of ionizing radiation UNIT - II X-ray Computed Tomography : Introduction, x-ray detectors in CT, imaging, cardiac CT, dual energy CT, Image quality, equipment, clinical use, biological effects and safety, latest advances UNIT – III Ultrasound imaging : Fundamentals of acoustic propagation, Generation & detection of Ultrasound, Ultrasonic Diagnostic Methods, Recent Developments, Image characteristics, Biological effects of ultrasound UNIT – IV Nuclear Medicine Imaging : Fundamentals of radio activity, Generation and Detection of Nuclear Emission, Diagnostic methods using radiation Detector probes, radionuclide Imaging systems, Recent developments, Internal radiation dosimetry and biological effects UNIT – V Magnetic resonance imaging : Fundamentals of Nuclear magnetic resonance, Generation and Detection of NMR signal, Imaging Methods, Invivo NMR Spectroscopy, Characteristics of magnetic resonance images, Biological effects of magnetic fields Text Book: 1 Suetens Paul, “Fundamentals of Medical Imaging” Cambridge University Press, 2 nd edition, 2008. Reference Books: 1. Dowsett, Kenny & Johnson, “The physics of Diagnostic Imaging”, Chapman & Hall Medical, Madras/London.(2011) 2. Shung K. Kirk, Tsui Benjamin, Smith.B.Michael, “Principles of Medical Imaging”.(2007) Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction 19 Course outcomes: 1. Describe the physics principles underlying the operation of medical imaging equipment ( pos:1) 2. Demonstrate an understanding of and apply mathematical methods of image construction and processing; explain the mode of operation of the major medical imaging techniques (pos: a,b) 3. Demonstrate an understanding of aspects of clinical applications of imaging methods and understand the advantages and disadvantages of the major imaging techniques.(pos:e,f,g) 4. Discuss radiation safety issues in the operation of medical imaging equipments.(pos: h,j) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What CIE To whom Max Marks Thrice (Average of the best two will be computed) Internal assessment tests Case study/Surprise test/ MCQS/Quiz/others SEE Frequency Students Once End of course (Answer any 5 of 10 questions) Middle of the course Standard examination Students feedback Evidence collected Course Outcomes Blue books 1 ,2,3,4, 10 answer scripts 1,2,3,4 10 answer scripts 1,2,3,4, Answer scripts 1,2,3,4, 30 100 - Feedback forms Students End of course End of course survey Questionnaire 1 to 4, Delivery of the course 1 to 4 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%) : Bloom Level Remember Understand Apply Analysis Evaluate Create T1 20 20 20 20 10 10 T2 10 30 20 20 10 10 T3 10 30 20 20 10 10 20 O THERS 0 0 20 40 20 20 SEE 20 20 20 20 10 10 ELECTIVE III COMPUTER COMMUNICATION NETWORKS Subcode: MLPE31 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam , Mr. Sanjay H S Course objectives: 1. Make the students appreciate the need and techniques of computer networking 2. Give conceptual understanding of physical and datalink layer 3. Introduce different protocols in medium access layers 4. Make the students analyze different features of network layers 5. Highlight the importance of transport and application layers Course contents: UNIT I Credits: 3:0:0 Contact Hours: 42 Introduction to Computer Networks: Introduction, advantages & applications of CCN, Computer network: structure, hardware, Topology, software & architecture, services, reference models: ISO & TCPIP UNIT II Physical Layer: Design issues, Digital Transmission, & Media types, multiplexing & types, Modems, switching techniques, ISDN Data Link Layer: design issues, Error detection & correction techniques, elementary data link layer protocols, pipelining, performance issues UNIT III Medium Access Layer: Network types, LAN, MAN & WAN, LAN protocols, IEEE 801, 802 & 803 standards UNIT IV Network Layer: Design issues, Connected & connectionless services, virtual circuits, datagram subnets, Routing algorithms, adaptive & non-adaptive algorithms, congestion control, internetworking, Internet layer, IP addressing UNIT V Transport layer: design & Performance issues, transport protocol mechanisms, TCP Application layer: DNS, Electronic Mail, World Wide Web, Multimedia Text Book: 1. Andrew S tanenbaum, “Computer Networks”, PHI, 2005 Edition Reference Book: 1. Leon Garcia & Widjaja, “Communication Networks”, Tata McGraw Hill Edition, 2000 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. 2. 3. Identify and solve the problems associated with computer networking ( pos: a, e ) Ascribe the different protocols to emphasize the importance of various layers present in networking ( pos; c, i) Analyze the different uses of networking technology (pos: a, i ) 21 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Others SEE Frequency Standard examination 10 10 End of course (Answer any 5 of 10 questions) 100 Course Outcomes Blue books 1,2 3 answer scripts 1 , 2,3 answer scripts 1 , 2,3 Answer scripts 1 , 2,3 Feedback forms - Students End of course End of course survey Evidence collected 30 Once Middle of the course Students feedback Max Marks Questionnaire 1 tio3 , Delivery of the course 1 to 3 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%): Bloom Level Remember Understand Apply Analysis Evaluate Create T1 30 30 30 10 - T2 T3 O THERS 30 30 30 30 30 30 30 30 30 10 10 10 MEDICAL DEVICES REGULATIONS SEE 30 30 30 10 - Subcode: MLPE32 Credits: 3:0:0 Prerequisite: Nil Contact Hours: 42 Course Coordinator(s): Mr. Mahendra S.J, Mrs. Purnima B.R Course objectives: 1. To make students gain knowhow about device regulations 2. To be well equipped with the knowledge of global policies on regulations 3. To understand the implications of the regulations 4. Are in a position to analyse the way design concepts are imbibed in practical scenarios. Course contents: UNIT - I The medical device as an entity: What is a medical device?, Defining the device, The product definition process, Overview of quality function deployment, The QFD process, The business proposal Reliability: Definition, Quality Vs Reliability, Reliability Vs Unreliability, Types of Reliability, Optimizing reliability, Reliability’s effects on medical devices. 22 Concept of Failure: Causes of Failure, Practical aspects of failure, Failure rates, Hardware failure, Software Failure, Failure due to human errors, Failures from customer’s point of view. Safety and Risk Management: Medical device safety and risk management, Effectiveness/performance of medical devices, Phases in the life span of a medical device, The risk management processes, Tools for risk estimation, Participants in ensuring the safety of medical devices, The role of each participant/stakeholder, Shared responsibility for medical device safety and performance UNIT - II Global Harmonization Task Force (GHTF): Objectives, Scope of the four GHTF study groups, Benefits of the GHTF, Final documents from the GHTF, Global Medical Device Nomenclature (GMDN) The Food and Drug Administration: History of device regulation, Device classification, Registration and listing, The 510 (k) Process, Declaration of conformance to a recognized standard, The PMA application, Investigational Device Exemptions (IDEs), Good Laboratory Practices (GLPs), Good Manufacturing Practices(GMPs), Human Factors, Design Control, The FDA and Software, Software classification, The FDA Inspection. UNIT - III The European Union: European Directives, European Standardization Bodies, European Standards Development Process, Other European Standards Considerations, Conformity Assessment and Testing, European Organization for Testing and Certification, the NVCASE Program The Medical Devices Directives: Definition of a medical device, The Medical Devices Directives process, Choosing the appropriate directive, Identifying the applicable essential requirements, Identification of corresponding harmonized standards, Essential requirements, Classification of the medical devices, identification and choice of a notified body. Unit - IV Standards and Regulations Background: Standards: What are standards? Voluntary and mandatory standards, Standards development process, Conformity assessment with standards, National and international standards systems, Identification of standards, Current trends in the use of standards in medical device regulations. The ISO 9000 Series of Standards. Unit – V Software and Quality system regulation: Software as a Technology, Domestic Software Regulations, Domestic Software Standards, International Software Regulations, International Software Standards, The Move Toward One Software Standard History of the quality system regulations, Scope, General provisions, Quality system, Design controls, Document controls, Purchasing controls, Identification and traceability, Production and process controls, Acceptance activities, Non-conforming product, Corrective and preventive action Text Books: 1. Reliable Design of Medical Devices, Second Edition by Richard Fries, CRC Press, 2006 2. Medical Device Quality Assurance and Regulatory Compliance by Richard C Fries, CRC Press, 1998 3. Medical device regulations: global overview and guiding principles By Michael Cheng, World Health Organization, 2003 4. Product Safety in the European Union by Gábor Czitán, Attila Gutassy, Ralf Wilde, TÜV Rheinland Academia, 2008 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction 23 Course outcomes: 1. Students will gain knowledge on : Overview of: discussion and focus on the new IVD and medical device regulations and a brief look at the following: Electromagnetic Compatibility Directive, Machinery Directive ● Low Voltage Directive, Non European requirements and GHTF/IMDRF (pos: a,k) 2. Students will be able to: Orient themselves to practical understanding Medical Devices classifications and understanding of the regulatory approval process. Determine which directives apply to which products, Classify medical devices, Assess borderline issues. (pos: b,h,k) 3. Students will be able to: Understand the different conformity assessment routes and how to select the most appropriate route for their product, understand the role of the essential requirements/harmonised standards and how to demonstrate conformity. Understand unique requirements of the IVD Directive, Understand the future direction of the medical device industry.(pos: b,e,g) 4. Students will be able to understand the role of risk management in pre- and post-market phases and be able to advice on a risk management policy and procedure.(pos:b,c,i) 5. Students will be able to understand the needs of payers and how to include these as part of the development of the device regulatory package.(pos: f,j) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination 10 10 End of course (Answer any 5 of 10 questions) 100 Middle of the course Students feedback Evidence collected Course Outcomes Blue books 1,2 ,3,4,5 answer scripts 1,2 ,3,4,5 answer scripts 1,2 ,3,4,5 Answer scripts 1, 2 and 3 30 Once Others SEE Max Marks Feedback forms - Students End of course End of course survey Questionnaire 21to 5, Delivery of the course 1to 5 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level Remember Understand Apply Analysis Evaluate Create T1 30 30 20 20 0 0 T2 30 30 20 20 0 0 T3 30 30 20 20 0 0 24 O THERS 30 30 20 20 0 0 SEE 30 30 20 20 0 0 MEDICAL ELECTRONIC DESIGN Subcode: MLPE33 Prerequisite: Nil Course Coordinator(s): Mr. Mahendra S.J, Mr.Basavaraj Hiremath Course objectives: 1. of design of medical equipments. 2. the biomedical signals. 3. the equipments. 4. for designing medical equipments.. Credits: 3:0:0 Contact Hours: 42 To help understand the need and importance To help understand how to filters to process To help understand the radiations emitted by To help understand standards and regulations Course contents: UNIT I Introduction, Definition of Medical Device, Medical Device Life cycle, Medical Device design cycle, Biopotential Amplifier: Characteristics, Single ended Biopotential Amplifier, Single ended Bio-potential Amplifier Arrays, Body Potential drivers. UNIT II Differential amplifiers, Simple Differential Bio-potential Amplifier, Op-amp Instrumentation amplifier, Instrumentation Biopotential Amplifier, Switched capacitor based Bio-potential Instrumentation Bio-potential Amplifier. UNIT III Band pass Selection for Bio-potential amplifier introduction, Wide band Bio-potential amplifier, Bio-potential amplifier with dc rejection, AC-coupled Instrumentation Bio-potential Amplifier front end, , Passive filter, Active filter, 50-60 Hz notch filter, Switched-capacitor filters: fourth, fifth ,eighth -order Butterworth low-pass. UNIT IV Radiated Emission : Fields radiated by a loop; straight wire. Differential mode radiation and common mode radiation. Radiation from non-sinusoidal sources and broadband sources. UNIT V Standards and Regulations Background: What are standards? Voluntary and mandatory standards, Standards development process, Conformity assessment with standards, National and international standards systems, Identification of standards, Current trends in the use of standards in medical device regulations. The ISO 9000 Series of Standards, The ISO 14000 Series of Standards, EN 46001, The ISO 13485 Standards, ISO 9000-3, IEC 601-1-4. The Medical Devices Directives, Choosing the appropriate directive, Identifying the applicable essential requirements, Identification of corresponding harmonized standards, Essential requirements, Classification of the device based on conformity, Medical Devices Directives, Active Implantable Medical Devices Directives, In-vitro Diagnostic Medical Devices Directives. Text Book(s): 1. “Design and development of Medical Electronic Instrumentation”, David Prutchi, Wiley publishers.(2005) 2. “The Designer’s Guide to Electromagnetic Compatibility”, Daryl Gerke and Bill Kimmel, Kimmel Gerke Associates Publishers “. (2002) 3. “Medical device regulations: global overview and guiding principles” , Michael Cheng, World Health 25 Organization publishers.(2003) References: 1. “Handbook of medical device design”, ” Richard C. Fries 1st edition, CRC Press. (2000) 2. “Execution, and Management of Medical Device Clinical Trials”, Salah Abdel-aleem, Wiley Publishers.(2009) 3. “Pharmaceutical and Medical Device Validation by Experimental Design”, Lynn D. Torbeck(2007) Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: Students will gain knowledge on : 1. Design medical equipments.(pos; a,b) 2. Take necessary care of the risk management in pre- and post-market phases and be able to advice on a risk management policy and procedure and .emissions from the equipments design.(pos: b,h,k) 3. Follow the standards and regulation during design and development process(pos:a,d,j) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Others SEE Frequency Standard examination Students feedback Max Marks Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 - Feedback forms Students End of course survey End of course Questionnaire Questions for CIE and SEE will be designed to evaluate the various educational components such as: Bloom Level Remember Understand Apply Analysis Evaluate T1 30 30 20 10 10 T2 30 30 20 10 10 T3 30 30 20 10 10 26 O THERS 30 30 20 10 10 SEE 30 30 20 10 10 1 to 3, Delivery of the course 1,2 and 3 Effectiveness of Delivery of instructions and Assessment methods Create 0% 0% 0% 0% 0% HUMAN ASSIST DEVICES Subcode: MLPE34 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Prof. P.G.Kumaravelu Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. To provide insight on the advancements in the assist devices in healthcare domain 2. To study the construction and working of various assist devices 3. To analyze the various human assist devices used in hospitals Course contents: UNIT I CARDIAC ASSIST DEVICES : Principle of External counter pulsation techniques, intra aortic balloon pump, Auxillary ventricle and schematic for temporary bypass of left ventricle, prosthetic heart valves. UNIT II HEMODIALYSERS: Artificial kidney, Dialysis action, hemodialyser unit, membrane dialysis, portable dialyser monitoring and functional parameters. UNIT III HEARING AIDS : Common tests – audiograms, air conduction, bone conduction, masking techniques, SISI, Hearing aids – principles, drawbacks in the conventional unit, DSP based hearing aids. UNIT IV PROSTHETIC AND ORTHODIC DEVICES : Hand and arm replacement – different types of models, externally powered limb prosthesis, feedback in orthodic system, functional electrical stimulation, sensory assist devices. UNIT V RECENT TRENDS: Transcutaneous electrical nerve stimulator, bio-feedback. Text Books: 1. Levine S.N. (ed), “Advances in Bio-medical engineering and Medical physics”, Vol. I, II, IV, inter university publications, New York, 1968 (Unit I, IV, V). 2. Kolff W.J, “Artificial Organs”, John Wiley and sons, New York, 1976. (Unit II ). 3. Albert M.Cook and Webster J.G, “Therapeutic Medical Devices”, Prentice Hall Inc., New Jersey, 1982 (Unit III). Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: On completion of this course, the students will be able to 1. 1. Demonstrate basic foundations of devices used in critical care and their applications (pos: a,k) 2. Illustrate the construction and working of various human assist devices in hospitals (pos:b,k) 3. Analyze the features of various human assist devices in healthcare (pos: e,h,i) 27 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 1 to 3 Delivery of the course 1,2 and 3 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level Remember Understand Apply Analysis Evaluate Create T1 10 30 30 25 05 00 T2 10 30 30 25 05 00 T3 10 30 30 25 05 00 O THERS 10 20 30 15 15 10 SEE 10 30 30 25 05 0 ERGONOMICS & REHABILITATION ENGINEERING Subcode: MLPE35 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Prof. P.G.Kumaravelu Course objectives: 1. To understand the foundations of ergonomics and rehabilitation engineering 2. To study the fundamental of ergonomics and task oriented principles 3. To understand the engineering principles behind the rehabilitation engineering 4. To apply the principles for visual, sensory applications 5. To study the orthopedic applications and design 28 Credits: 3:0:0 Contact Hours: 42 Course contents: UNIT – I Introduction: Focus of ergonomics & its applications, Body mechanics: Basics, Anatomy of Spine & pelvis related to posture, postural stability & adaptation, Low back pain, risk factors for musculoskeletal disorders in workplaces, Anthropometric principles in workspace: Designing for a population of users, Human variability sources, applied anthropometry in ergonomics & design, anthropometry & personal space UNIT – II Design of repetitive tasks: Work related musculoskeletal disorders, injuries to upper body at work, neck disorders, carpal tunnel syndrome, tennis elbow, shoulder disorder, ergonomic interventions. Design of physical environment: human thermoregulation, thermal environment, working in hot & cold climates, skin temperature, protection against extreme climates, comfort & indoor climate, ISO standards UNIT-III Engineering concepts in rehabilitation Engineering. Anthropometry: Methods for Static and dynamic Measurements: Area Measurements, Measurement of characteristics and movement, Ergonomic aspects in designating devices: Introduction to Models in Process Control, Design of Information Devices, Design of Controls Active Prostheses: Active above knee prostheses. Myoelectric hand and arm prosthesesdifferent types, block diagram, signal flow diagram and functions. The MARCUS intelligent Hand prostheses UNIT-IV Engineering concepts in sensory rehabilitation Engineering. Sensory augmentation and substitution: Visual system: Visual augmentation, Tactual vision substitution, and Auditory vision substitution. Auditory system: Auditory augmentation, Audiometer, Hearing aids, cochlear implantation, visual auditory substitution, tactual auditory substitution, Tactual system: Tactual augmentation, Tactual substitution, UNIT-V Orthopedic Prosthetics and Orthotics in rehabilitation: Engineering concepts in motor rehabilitation, applications. Computer Aided Engineering in Customized Component Design. Intelligent prosthetic knee. A hierarchically controlled prosthetic hand. A self-aligning orthotic knee joint. Externally powered and controlled Orthotics and Prosthetics. FES systems-Restoration of hand function, restoration of standing and walking, Hybrid Assistive Systems (HAS). Text Books: 1. Introduction to Ergonomics by R S Bridger, Routledge Taylor & Francis group, London ,2008 2. Bronzino, Joseph; Handbook of biomedical engineering. 2nd edition, CRC Press, 2000. 3. Robinson C.J Rehabilitation engineering. CRC press 1995 Reference Books: 1. Fitting the task to human, A textbook of occupational ergonomics, 5th edition, Taylor & Francis, ACGIH publications , 2008 2. Work study & Ergonomics by Dhanpat Rai & sons, 1992 3. Horia- Nocholai Teodorecu, L.C.Jain , Intelligent systems and technologies in rehabilitation engineering; CRC; December 2000. 4. Etienne Grandjean, Harold Oldroyd, Fitting the task to the man, Taylor & Francis,1988. Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: the students will be in a position to: 1. 2. 3. 4. Understand the principles behind the ergonomics and rehabilitation engineering.(pos: a,k) Analyze the task oriented principles of ergonomics (pos:b,k) Understand the visual, augmented and sensory principles of rehabilitation engineering (pos: a,b,i,j,k) Apply the concepts for various clinical applications (pos: e) 29 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 , 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 1 to 4 Delivery of the course 1 to 4 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as: Bloom Level Remember Understand Apply Analysis Evaluate Create T1 20 35 15 10 10 10 T2 20 35 15 10 10 10 T3 20 35 15 10 10 10 O THERS 20 35 15 10 10 10 VLSI DESIGN Subcode: MLPE36 Prerequisite: Nil Course Coordinator(s): Mrs. Prabhu Ravikala Vittal, Mrs. Chandana S Course objectives: 1. To provide insight on the advancements in the field of VLSI technology 2. To study the various concepts of VLSI in circuit design and evaluation 3. To analyze the applications of VLSI in engineering technology Course contents: UNIT I 30 SEE 20 35 15 10 10 10 Credits: 3:0:0 Contact Hours: 42 INTRODUCTION: Historical perspective, circuit design example, VLSI Design methodologies, hierarchy, Concept of modularity, regularity, locality, Design styles ,Packaging, CAD. Fabrication of MOSFETS: CMOS NWELL, Layout design rules UNIT II MOS Transistor : Structure, external biasing, operation ,V I Characteristics, scaling, MOS Capacitor.MOS Inverter: Static characteristics: Resistive load inverter, N type load, CMOS Inverter UNIT III Dynamic switching characteristics: Delay time, calculation of delay time, rise and fall times, resistance ,capacitance estimation, Switching power dissipation, super buffers. UNIT IV Combinational MOS static Logic circuits: NMOS Depletion load complex logic circuits,Pass transistor, Transmission gate, stick diagrams, mask layout. Sequential circuits: SR Latch, CMOS D Latch, edge triggered flip flop. Dynamic logic circuits: Basic principles of PT circuits, Dynamic CMOS circuit techniques: CMOS TG logic, Dynamic CMOS logic High performance Dynamic circuits, charge sharing problems, remedies. UNIT V Design for testability: Fault type and models, Controllability, Observability, Ad hoc testing, scan based techniques, BIST, IDDQ. Text books: 1. Sung – Mo Kang, Yusuf Leblebici“CMOS digital integrated circuits—Analysis and Design “ Tat McGraw Hill 3 rd Edition 2003 Reference Books: 1. Kamran Eshraghian, Dougles and A. Pucknell, “Essentials of VLSI circuits and systems” - PHI, 2005 Edition. 2. Weste and Eshraghian, “Principles of CMOS VLSI Design” - Pearson Education,1999. 3. John P.Uyemura,”Chip Design for Submicron VLSI: CMOS Layout & Simulation,” - Thomson Learning, 2005. 4. John .P. Uyemura,” Introduction to VLSI Circuits and Systems” - JohnWiley, 2003. 5. John M. Rabaey,”Digital Integrated Circuits” - PHI, EEE, 1997. 6. Wayne Wolf, “Modern VLSI Design” - Pearson Education, 3rd Edition Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Analyze the CMOS layout levels, how the design layers are used in the process sequence. (pos: a,j) 2. Describe the general steps required for processing of CMOS integrated circuits. (pos: a,j) 3. Be able to design static CMOS combinational and sequential logic at the transistor level, including mask layout. (pos: a,e,j) 4. Design using different logic styles such as complementary CMOS logic, pass-transistor logic, dynamic logic, etc. (pos: a,e,j) 5. Have the skill of transistor-level analysis and design of simple and complex logic gates such as inverter, NOR and NAND gates. (pos: a,e,j) 31 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 2 ,3 answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey 1, 2 and 3 Answer scripts Questionnaire 1 to5 Delivery of the course 1 to5 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level Remember Understand Apply Analysis Evaluate Create T1 30 30 10 10 10 10 T2 30 30 10 10 10 10 T3 30 30 10 10 10 10 O THERS 30 30 10 10 10 10 SEE 30 30 10 10 10 10 ELECTIVE IV ADVANCED MEDICAL INSTRUMENTATION TECHNOLOGY Subcode: MLPE41 Prerequisite: Nil Course Coordinator(s): Mrs.Uma Arun , Mrs. Prabha Ravi Course objectives: 32 Credits: 3:0:0 Contact Hours: 42 1. 2. 3. 4. 5. To develop an understanding of Neurological equipments in understanding and analyzing electrical signals from brain. To develop an understanding of purpose and use of of impedance based measurements. To develop an understanding of use of lasers in medical applications To develop an understanding of various ambulatory and anesthesia machines. To introduce students to various computer assisted devices and their applications. Course contents: UNIT I Implantable Stimulators and Defibrillators: Implantable Stimulators for Neuromuscular Control, block diagram, Implanted FES hand grasp system, packaging of implantable electronics, leads and electrodes, safety issues of implantable stimulators, clinical use. Implantable Defibrillators, Pulse Generators, Electrode Systems (“Leads”), Arrhythmia Detection and Therapy, Implantable Monitoring UNIT II Impedance Based Measurements: Bioelectric impedance measurement methods, modeling, respiration and apnea monitoring, cardiac measurements, body composition, Electrical Impedance Tomography: Electrical impedance property and conduction in human tissues, determination of the impedance distribution, data acquisition, BASICS OF image reconstruction, optimal current patterns, three dimensional imaging, single step imaging, differential imaging, Areas of clinical applications UNIT III Biomedical Lasers and Special Instruments: Biomedical Laser Beam Delivery Systems, Nonpulsatile Spectroscopy, Optical Instruments: computerized tonometer, Keratometers, Diffusion tensor imaging, Dual Energy X -ray Absorptiometry (DEXA) imaging, near-infrared spectroscopic imaging, functional Magnetic Resonance Imaging (fMRI), Virtual reality: overview, medical applications, UNIT IV Anesthesia and Ambulatory Systems: Anesthesia Delivery System: gases used during Anesthesia and their sources, gas blending and vaporization system, breathing circuits, monitoring the function of the anesthesia delivery system, monitoring the patient. Ambulatory Monitoring: Ambulatory Holter Device, Ambulatory Blood Pressure Monitoring, Ambulatory Blood Glucose Monitoring, UNIT V Automated and Computer Assisted Techniques: Automated Arrhythmia Analysis, Intelligent patient monitoring, EEG-based brain-computer interface system, EEG brain mappers: principles and measurements, computer-assisted detection and diagnosis, Virtual Instrumentation and Biomedical Engineering – case studies, cryosurgery, cryotherphy, robotic surgery, wearable medical devices, risk management for medical devices Text books: 1. J. D. Bronzino, Biomedical Engineering Handbook, CRC Press, second edition, 2000. 2. Metin Akay , Wiley - Encyclopedia of Biomedical Engineering - 6 Vol. Set, John Wiley & Sons, Inc., Publication, 2006. Reference books: 1. Steve Webb, “Physics of Medical Imaging”, Taylor and Francis, 1988. 2. R. Hendee and Russell Ritenour “Medical Imaging Physics”–William, Wiley, Fourth Edition, 2002. 33 3. Myer Kutz Publisher , “Standard handbook of Biomedical Engineering and Design” McGraw – Hill, 2003. 4. P.Raghunathan, “Magnetic Resonance Imaging and Spectroscopy in Medicine”, Orient Longman, 2007. Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Analyze the use of advances of various stimulators (pos: a,c) 2. Connect the concepts with that of the equipment and arrive at critical reviews using examples. (pos: a,c) 3. Relate the application of the devices studied to various physical diseases and disorders. (pos: a,b,c,d,h) 4. Communicate effectively their understanding both via written and oral communication.(pos: a,c) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2, 3 and 4 answer scripts 1 and 2 answer scripts 1,2, 3 and 4 Answer scripts 1,2, 3 and 4 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2, 3 and 4 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level Remember Understand Apply Analysis Evaluate Create T1 20 30 20 20 10 0 T2 20 30 20 20 10 0 T3 20 30 20 20 10 0 TELEMEDICINE Subcode: MLPE42 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Mrs.Chandana S O THERS 20 30 20 20 10 0 SEE 20 30 20 20 10 0 Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. To understand basic principles of Telemedicine 2. To study various types of communication and wireless technology in patient monitoring 3. To interpret various data security and standards used for transmission 4. To understand the importance of caring for the community and future trends in healthcare 34 Course contents: UNIT I Introduction : Information Technology and Healthcare Professionals -Providing Healthcare to Patients -Technical Perspective - Healthcare Providers -Healthcare Informatics Developments - Different Definitions of Telemedicine Overview on telemedicine - The Growth of the Internet: Information Flooding in E-Health Communication Networks and Services Wireless Communications Basics -Wired vs. Wireless -Conducting vs. Optical Cables - Data Transmission Speed Types of Wireless Networks-the Outdoor Operating Environment - RFID in Telemedicine UNIT II Wireless Technology in Patient Monitoring - Body Area Networks - At the Scene - Network Backbone - At the Hospital - Remote Recovery - At Sea -Forests and Mountains -Buildings on Fire - At the Hospital - People Tracking -Electromagnetic Interference on Medical Instrument -General Health Assessments Technologies in Medical Information Processing Collecting Data from Patients - Bio-signal Transmission and Processing -Patient Records and Data Mining Applications -Knowledge Management for Clinical Applications Electronic Drug Store UNIT III Wireless Telemedicine System Deployment Planning and Deployment Considerations -The OSI Model - Site Survey -- Standalone Ad Hoc Versus Centrally Coordinated Networks -Link Budget Evaluation - Antenna Placement -Scalability to Support Future Growth - Cellular Configuration - Multiple Access -Integration with Existing IT Infrastructure - Evaluating IT Service and Solution Provider -Quality Measurement UNIT IV Technologies for Safeguarding Medical Data and Privacy Information Security Overview – Risks- Safeguarding Patient Medical History - National Electronic Patient Record - Personal Controlled Health Record - Patients’ Concerns - Anonymous Data Collection and Processing -Biometric Security and Identification UNIT V Caring for the Community Telecare - Telehealth - Safeguarding the Elderly and the Aging Population Telemedicine in Physiotherapy - Healthcare Access for Rural Areas - Healthcare Technology and the Environment Future Trends in Healthcare Technology Prognostics in Telemedicine - The Aging Population: Home Care for the Elderly - Smart Home Assistive Technologies -Clothing Technology and Healthcare - Haptic Sensing for Practitioners - The Future of Telemedicine and Information Technology for Everyone Text book: 35 1. Bernard Fong,A.C.M. Fong,C.K. Li, Telemedicine Technologies:Information Technologies in Medicine and Telehealth, John Wiley & Sons, 2011 Reference Book: 1. A.C.Norris, Essentials of Telemedicine and Telecare, John Wiley & Sons, 2002 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: The students should be able to :On completion of this course, the students will get insight on 1. recognize the basic principles and operations of telemedicine.(pos: a,d,f,i) 2. Identify the benefits that Telehealth brings to the different targeted audiences (pos: c,k) 3. Describe and explain a range of use cases, such as remote monitoring of non-communicable diseases, home based and mobile self-management tools, hospital-at-home and remote diagnostics (pos: c,j,k) 4. Identify the conditions for successfully implementing telemedicine and e-health services and to apply telemedicine and e-health services in professional health work (pos: f,h,i) Assessment and Evaluation vis-à-vis Course Outcomes: Indirect Assessment Methods Direct Assessment Methods What C I E Internal assessment tests Quiz Case Studies S E E To whom Students Standard examination Students feedback End of course survey When/ Where (Frequency in the course) Thrice(Average of the best two will be computed) Twice twice End of course (Answering 5 of 10 questions) Middle of the course Max marks Evidence collected 30 Blue books CO1,CO2,CO,CO 4 10 10 Result sheets reports CO2,CO3,CO4 CO1,CO2,CO3 100 Answer scripts CO1,CO2,CO3,C O4 - Feedback forms CO1,CO2,CO3 - Question-naire CO1,CO2,CO3,C O4 Students End of course Contributing to Course Outcomes Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 Remember Understand Apply Analysis Evaluate Create 30 40 20 10 - 20 50 30 0 - 20 40 20 10 - O THERS 1 2 20 60 30 10 20 10 10 40 - SEE 30 40 20 10 - BIOGRID COMPUTING Subcode: MLPE43 Credits: 3:0:0 36 Prerequisite: Nil Contact Hours: 42 Course Coordinator(s): Dr.N.Sriraam, Mr.Sanjay H.S Course objectives: 1. 1. To understand the basics of grid and distributed computing 2. To study various grid related services 3. To analyze the importance of grid monitoring and scheduling 4. To understand the workflow management of various grid portals 5. To study the importance of grid computing in healthcare applications Course contents: UNIT I GRID AND DISTRIBUTED COMPUTING: Importance of grid-characterization of the grid- grid related standards bodies- architecture of the Grid-. traditional paradigms for distributed computing- web services- OGSA- The Globus Toolkit 3 (GT3)-OGSA-DAI-WSRF. UNIT II SEMANTIC GRID AND GRID SECURITY: Semantic grid -metadata and ontology in the semantic web-semantic web services-semantic grid activities-autonomic computing-features of autonomic computing systems.-autonomic Grid services- need for grid security- Brief Security Primer.- Cryptography.- Grid Security and its topologies.possible vulnerabilities UNIT III GRID MONITORING AND SCHEDULING: Importance of grid monitoring-grid monitoring architecture (GMA)grid monitoring systems.-grid scheduling and resource management-scheduling paradigms-. Scheduling WorksCondor, SGE, PBS and LSF- Grid Scheduling with QoS UNIT IV WORK FLOW MANAGEMENT AND GRID PORTALS: Importance of Workflow Management for the GridWorkflow Management Coalition-Web Services-Oriented Flow Languages.- Grid Services-Oriented Flow Languages-salient features of grid portals- First-Generation Grid Portals- Second-Generation Grid Portals UNIT V STUDIES IN HEALTH TECHNOLGIES AND INFORMATICS: State of the Art of the Grid Research and Use at Molecule Level- Grid-based Analysis of Tandem Mass Spectrometry Data in Clinical Proteomics- Sleep Medicine as a Scenario for Medical Grid Application- ImmunoGrid – The Virtual Human Immune System ProjectGrid-supported Medical Digital Library- Data Integration in eHealth Text Books: 1. Maozhen Li, Mark Baker , The Grid: Core Technologies, John Wiley,2005 2. Nicolas Jacq, Henning Müller, Ignacio Blanquer, Yannick Legré, Vincent Breton, Dominique Hausser, Vicente Hernández, Tony Solomonides, Martin Hofmann-Apitius, From Genes to Personalized HealthCare: Grid Solutions for the Life Sciences – IOS Press, 2007 Reference Book: 1. Manuela Pereira, Mario Freire, "Biomedical Diagnostics and Clinical Technologies: Applying HighPerformance Cluster and Grid Computing", Medical Information Science Reference,,2010 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction 37 Course outcomes: the students will get insight on 1. 2. 3. Fundamental knowledge on the basics of grid computing (pos:a,k) Understanding various grid level architecture and grid security (pos: b,k) Application of grid for healthcare applications (pos: b) Indirect Assessment Methods Direct Assessment Methods Assessment and Evaluation vis-à-vis Course outcomes : What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 PHYSIOLOGICAL SYSTEM MODELLING Subcode: MLPE44 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Dr.C.K Narayanappa Course objectives: 1. To understand the importance and basics of physiological system 38 Credits: 3:0:0 Contact Hours: 42 2. 3. 4. 5. To study the fundamental electrical properties of the system To analyze the system transfer function and impedance for various physiological conditions To apply the principles of feedback and analyze the system To study the application of various physiological model for different clinical conditions Course contents: UNIT I PROPERTIES OF SYSTEMS AND ELECTRICAL ANALOG : System concept, system properties – Resistance, storage, resistance – compliance, piece-wise linear approximation, electrical analog for compliance, thermal storage, step response of first order systems – resistance- compliance systems, and pulse response of first order systems UNIT II TRANSFER FUNCTIONS: Transfer functions and its use, Study of transfer function of first order and second order systems, engineering concept in coupled system, example of Transformed signals. UNIT III IMPEDANCE CONCEPT: Transfer functions with impedance concept, prediction of performance, identification of the system from impedance function, periodic signals, relationship between transfer function and sinusoidal response, evaluation of transfer function from frequency response. UNIT IV FEEDBACK SYSTEMS: Characteristics of physiological feedback systems, stability analysis of systems. UNIT V SIMULATION OF BIOLOGICAL SYSTEMS: Simulation of thermal regulation, pressure and flow control in circulation, occulo motor system, endocrinal system, functioning of receptors. Text Books: 1. William B.Blesser, “ System approach to Bio-medicine”, McGraw-Hill, New York, 1969. 2. Manfred Clynes and John H.Milsum, “Bio-medical engineering system”, McGraw-Hill , NewYork, 1970. 3. Michael C.K. Khoo,” Physiological Control Systems -Analysis, Simulation and Estimation” Prentice Hall of India Pvt. Ltd., New Delhi, 2001 Reference Books: 1. Douglas S. Rigg, “Control theory and physiological feedback mechanism”, The William & Williams co., Baltimore, 1970. Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: The students will: 1. Understand the principles behind the physiological system modeling (pos: a,k) 2. Analyze the various resistive and storage properties of the physiological system (pos: b,k) 3. Evaluate the impedance and system stability and feedback (pos: a,b,I,j,k) 4. Apply the concepts for various clinical applications (pos:e) Assessment and Evaluation vis-à-vis Course outcomes : Direct Assessment Methods What CIE To whom Internal assessment tests Students Others Frequency Thrice (Average of the best two will be computed) Once Others Once 39 Max Marks Evidence collected Course Outcomes Blue books 1,2, 3 and 4 answer scripts 1 and 2 answer scripts 1,2, 3 and 4 30 10 10 End of course (Answer any 5 of 10 questions) Middle of the course Standard examination SEE Indirect Assessment Methods Students feedback 100 Answer scripts - Feedback forms Students End of course survey End of course Questionnaire 1,2, 3 and 4 2 & 3, Delivery of the course 1,2, 3 and 4 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 10 60 10 10 05 05 10 60 10 10 05 05 10 60 10 10 05 05 10 60 10 10 05 05 10 60 10 10 05 05 INTRODUCTION TO BIOMEDICAL NANOTECHNOLOGY Subcode: MLPE45 Credits: 3:0:0 Prerequisite: Contact Hours: 42 Engineering Physics Course Coordinator(s): Mrs. Supriya Babu, Dr.N.Sriraam Course objectives: 1. To provide an overview of various trends in nanotechnological applications towards drug delivery, Implants & Prostheses, Biodefense and in medicine and surgery 2. To understand many possibilities and realities of applications of nanotechnology in medicine. Course contents: UNIT I Introduction: Converging Technologies: Nanotechnology and Biomedicine Materials Science, Disease-Specific Microtechnologies, Diabetes, Cardiovascular Disease, Remote Sensing, Gastrointestinal Tract, Oncology, Applications to Epilepsy, Hydrocephalus, and Neurotrauma, Surgical Technology, Potential Risks and Remedies: Nanomaterials in the Human Body, Implants, Bone Regeneration, Diagnosis and Treatment of Diseases, Cosmetics, Toxicities of Nanomaterials, Nanoparticles, Fullerenes, Carbon Nanotubes. UNIT II Nanotechnology and Nanobiomedicine, Toward Biomolecular Medicine, Drug Synthesis and Delivery, Implants and Prosthesis, Diagnostics and Screening, Nanotechnology Platforms for Biomedicine. Nanotechnology and Trends in Drug Delivery Systems with Self-Assembled Carriers: Introduction, Toward Development of Drug Delivery Systems with Bionanotechnology, Nanoparticles and Nano-Sized Spaces, Quantum 40 Dot (Semiconductor Nanoparticle), Safety of the Human Body and the Environment. UNIT III Implants and Prostheses: Introduction, Biomaterials, Biological Processes, Biomaterial Interface Processes, Foreign Body Reaction Nanotechnology in Implantology: Current Nanofabrication Methods, Lithography, Colloidal Resists, Self-Assembly Systems, Soft Lithography, Biomimetic Approaches, DNA Coatings, Influence of Biomaterials with Nanostructures on Cell Behavior, Topographical Nanostructures, Protein and Peptide Nanostructures, Calcium Phosphate Nanostructures, Natural versus Synthetic UNIT IV Nanostructures Nano-Enabled Components and Systems for Biodefense: Introduction, Sensor Component of NanoEnabled Biodefense, Nano-Enabled Sensors for Monitoring: Exposures, Airborne Exposures, Contact Exposures Nanomaterials as Enablers for Biodefense, Integration and Multifunctional System Concepts UNIT V Nanobiology in Cardiology and Cardiac Surgery- Diagnostic Applications of Nanobiology and Nanotechnology: Molecular Imaging of Angiogenesis, Fluid Acceleration Sensors, Therapeutic Applications, Smart Drugs, Nanorobotics, DNA-based Nanodevices, Angiogenesis Assist Devices, The “Clottocyte” Applications in the Therapy of Myocardial Ischemia, Extracorporeal Circulation / Restoration of Coronary Flow/Reperfusion, Nanotechnological Applications in Trauma / Bleeding / Wound Healing in Cardiac Surgery, Nanotechnology and Aortic Surgery, Tissue Engineering of Bioartificial Heart Muscle/Stem Cell Transfer, for Myocardial Restoration and Nanobiology Text Books: 1. BIOMEDICAL NANOTECHNOLOGY by edited Neelina H. Malsch; CRC Press, Taylor & Francis Group(2005) 2. Nanoscale Technology in Biological Systems edited by Ralph S. Greco, Fritz B. Prinz, R. Lane Smith; CRC Press (2004) Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Place the developments in the field of biomedical nanotechnology in social and economic contexts (pos: h) 2. Understand the ethical issues involved in the development of nanotechnology solutions for biomedical field (pos: f) Assessment and Evaluation vis-à-vis Course outcomes : Direct Assessment Methods What CIE To whom Internal assessment tests Students Others Frequency Max Marks Thrice (Average of the best two will be computed) Once 30 Once 10 Others 41 10 Evidence collected Course Outcomes Blue books 1,2 answer scripts 1 and 2 answer scripts 1, 2 End of course (Answer any 5 of 10 questions) Middle of the course Standard examination SEE 100 Answer scripts Indirect Assessment Methods 1 & 2, Delivery of the course 1,2 Effectiveness of Students End of Delivery of End of course survey Questionnaire course instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%): Students feedback - 1, 2 Feedback forms Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 30 30 20 20 00 00 20 40 20 20 00 00 20 40 20 20 00 00 30 30 20 20 00 00 30 30 20 20 00 00 PATTERN RECOGNITION Subcode: MLPE46 Prerequisite: Nil Course Coordinator(s): Mr.Basavaraj Hiremath, Dr.N.Sriraam Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. To provide insight on pattern recognition 2. To study various pattern recognition algorithms 3. To analyze the suitability of various algorithm for clinical diagnostic applications Course contents: UNIT I Introduction: Machine perception, pattern Recognition systems, Design cycles, learning and adaptation Probability: Random variable, joint distribution and densities, moments of random variable. UNIT II Statistical decision making:Introduction, Baye's theorem, multiple features, conditionally independent features, decision bounderies, unequal costs of error, estimation of error rates, problems. UNIT-III Non parametric Decision making: Introduction, Histograms, kernel and window estimators, nearest neighbor classification techniques, adaptive decision boundaries, adaptive discriminate functions.Minimun Squared Error Discriminant Functions UNIT-IV Clustering: Introduction, Hierarchical clustering:,Single-Linkage Algorithm,Complete-Linkage Algorithm,Average –Linkage Algorithm,Ward’s Method Algorithm problems. 42 Partitional clustering :Forgy’s Algorithm, K-means Algorithm, Isodata Algorithm,problems. UNIT-V Processing of waveforms and images: Introduction, gray level scaling transformations, equalization, geometric image scaling and interpolation, edge detection, laplacian and sharpening operators, line detection and template matching, logarithmic gray level scaling. TEXT BOOK: 1. Pattern Recognition and Iamge Analysis, Earl Gose, Richard Johnson Baugh and Steve jost, PHI (2004) REFERENCE BOOKS: 1. Richard O.Duda, Peter E.Herd and David & Stork, pattern and classification, john Wiley and sons, Inc 2 Ed.2001. 2. Robert Schlkoff, Pattern Recognition: S tatistical Structural and Neural Approaches, John Wiley and sons, Inc, 1992 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: On completion of this course, the students will get insight on 1. 2. 3. To recognize the importance of pattern recognition (pos: a,c,e,i) To review and interpret the pattern recognition principles(pos: a,c,e) To test the various pattern recognition algorithms for various applications(pos: c,e,i,k) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as (%): Bloom Level T1 T2 T3 OTHERS SEE Remember 20 20 20 20 20 43 Understand Apply Analysis Evaluate Create 35 15 10 10 10 35 15 10 10 10 35 15 10 10 10 35 15 10 10 10 35 15 10 10 10 ELECTIVE V DATA MINING AND HEALTHCARE APPLICATIONS Subcode: MLPE51 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Mr.Sanjay H.S Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. To understand the foundation level of data mining 2. To study various clustering and data warehouse principles 3. To analyze the data mining algorithms 4. To apply the principles for classification, prediction and clustering 5. To study the application of data mining for clinical environment Course contents: UNIT I DATA MINING CONCEPTS: Fundamentals of data mining – patterns and data- functionalities – classification of data mining systems- task primitives- integration with data warehouse- machine learning and statistics-input: concepts, instances ,attributes and output: knowledge representation UNIT II DATA PREPROCESSING AND DATA WAREHOUSE: Need for pre-processing- descriptive data summarizationdata cleaning- data integration, transformation and reduction, Data discretization and concept hierarchy generationImportance of data warehouse-multidimensional data model –data ware house architecture-implementation -Data Warehousing to Data Mining UNIT III DATA CUBE COMPUTATION, GENERALIZATION AND MINING PATTERNS Efficient Methods for Data Cube Computation - Development of Data Cube and OLAP Technology-Attribute-Oriented Induction—Method for Data Generalization and Concept Description- importance of mining patterns- Efficient and Scalable Frequent Item set Mining Methods - Mining Various Kinds of Association Rules -Association Mining to Correlation Analysis Constraint-Based Association Mining UNIT IV CLASSIFICATION, PREDICTION and CLUSTER ANALYSIS: Importance of classification and prediction – issues-classification by Decision Tree Induction - Bayesian Classification- Rule-Based ClassificationClassification by Backpropagation - support Vector Machines - Associative Classification: Classification by Association Rule Analysis- Prediction - Accuracy and Error Measures- Evaluating the Accuracy of a Classifier or 44 Predictor -Cluster Analysis-Types of Data in Cluster Analysis Clustering Methods - Model-Based Clustering Methods UNIT V APPLICATIONS:Mining Data Streams - Mining biosignal time-series data -mining sequence patterns in transactional databases-mining sequence patterns in biological data- Applications: cancer detection, kidney failure and survival prediction Text Books: 1. Jiawei Han and Micheline Kamber, Data Mining: Concepts and Techniques, Morgan Kaufmann Publishers, 2000 (ISBN: 1-55860-489-8). 2. Ian H. Witten and Eibe Frank , Data Mining: practical machine learning tools and techniques with Java implementations, Morgan Kaufmann Publishers, San Fransisco, CA , (2000). Reference Books: 1. Alex A. Freitas, Data mining and knowledge discovery with evolutionary algorithms, Sprtiner,2010 2. Dorian Pyle, Data Preparation for Data Mining , Morgan Kaufmann, 1999 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: the students will : 1. Understand the Basics of the data mining principles (pos: a,k) 2. Analyze the clustering and various datamining rules (pos: b,k) 3. Apply the concepts for various clinical applications (pos: e) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 45 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 CLINICAL ENGINEERING Subcode: MLPE52 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam, Mrs. Supriya Babu Course objectives: 1. 2. 3. 4. Credits: 3:0:0 Contact Hours: 42 To understand the role of clinical engineer and importance of clinical engineering To study various management perspectives of clinical engineering To acquire the necessary learning skills To apply the acquired engineering skills on clinical applications Course contents: UNIT I Definition, role of clinical engineering within the hospital organization, major functions of a clinical engineering department, flowchart and model of a clinical engineering department, computerized maintenance and management system, clinical information systems, picture archiving and communication systems (PACS). UNIT II Duties and responsibilities, clinical engineer as consultant, clinical engineer as investigator and expert witness. patient safety and clinical engineers, accident investigation, electromagnetic interference, WMTS interference issues. UNIT III Technology evaluation, strategic technology planning, technology and alternatives, risks, hazards, and clinical efficacy, conceptual needs analysis, testing laboratory and engineering evaluation, technical specifications and other requirements. UNIT IV Management engineering in health care, cost effectiveness and productivity, personnel management, medical technology assessment process, in-house clinical and technical evaluations, planning strategies, quality. UNIT V Medical technology management practices, health care strategic planning utilizing technology assessment, vendor and service management, medical device research and design, maintenance and repair of medical devices, medical device troubleshooting, safety standards and regulations. Text Book: 1. Joseph Dyro B.S. Clinical Engineering Handbook, Elsevier Academic Press, 2004. 46 Reference Books: 1. Yadin David, Clinical Engineering, Principles and Applications in Engineering Series, CRC Press, 2003. 2. Michael Nowicki, The Financial Management of Hospitals and Healthcare Organizations, Blackwell Publishing Ltd, 2004. Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: the students will : 1) recognize the roles and responsibilities of clinical engineers. (pos: a,d,f,i) 2) identify the needs of the hospital equipments as well as to employ the necessary safety standards (pos: c,k) 3) formulate the strategic plans for technology assessment (pos: j,k) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 10 60 10 10 5 5 10 60 10 10 5 5 10 60 10 10 5 5 10 60 10 10 5 5 10 60 10 10 5 5 INTRODUCTION TO CLOUD COMPUTING Subcode: MLPE53 Credits: 3:0:0 Prerequisite: Nil Contact Hours: 42 Course Coordinator(s): Mr. Sanjay H.S , Mrs. Prabha Ravi Course objectives: 47 1. Introduce the basics of cloud and their models 2. Explore the various standards, services, issues and the licensing aspects in cloud 3. Provide an insight into the aspects of Cloud management and virtualization 4. Elaborate on Cloud storage and recent advancements in cloud computing Course contents: UNIT 1 Introduction to Middleware Technologies and its classification: Distributed System Models and Enabling Technologies; Scalable Computing Service over the Internet; System Models for Distributed and Cloud Computing; Software Environments for Distributed Systems and Clouds; Performance, Security, and Energy-Efficiency. UNIT II Design of Cloud Computing Platforms: Cloud Computing and Service Models; Architecture Design of Compute and Storage Clouds; Public Cloud Platforms: GAE, AWS and Windows Azure; Inter- cloud Resource Management; Cloud Security and Trust Management. UNIT III Service Oriented Architectures: Services and Service Oriented Architectures; Message-Oriented Middleware; Discovery, Registries, Metadata, and Databases; Workflow in Service-Oriented Architectures. UNIT IV Cloud Programming and Software Environments: Features of Cloud and Grid Platforms; Parallel and Distributed Programming Paradigms; Programming Support of Google App Engine; Programming on Amazon AWS and Microsoft Azure; Emerging Cloud Software Environments. UNIT V Grid Computing Systems and Resource Management: Grid Architecture and Service Modeling; Grid Resource Management and Brokering; Software and middleware for Grid Computing; Grid Application Trends and security measures: Trust models for grid security enforcement, Authentication and Authorization methods, GSI. On-Line Social and Professional Networking. Text Book: 1. Kai Hwang, Jack Dongarra, Geoffrey Fox: Distributed and Cloud Computing - From Parallel Processing to the Internet of Things, First Edition, MK Publishers, 2012. Reference Books: 1. Anthony T. Velte, Toby J. Velte, Robert Elsenpeter: Cloud Computing, A Practical Approach, McGraw Fill, 2010. 2. C.S.R.Prabhu: Grid and Cluster Computing, 1 st Edition, PHI, 2010. 3. Joshy Joseph, Craig Fellenstein: Grid Computing, First Edition, Pearson Education, 2011 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1) Reminisce the basics of cloud and cloud models (pos: a,e) 2) Accent the standards and security issues in cloud and cloud licensing approaches(pos: a,c) 3) Quote the fundamentals of cloud and relate the same to the software plus services(pos: a, i) 4) Explore the techniques and approaches involved with management and virtualization of cloud(pos: e,i) 5) Conjoin the principles of cloud computing and cloud storage and expand the same to study the applications of cloud computing (pos: a,i) 48 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1, 2,3,4 answer scripts 5 answer scripts 1, 2,3,4,5 Answer scripts 1,2,3,4,5 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire Delivery of the course Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as: Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 30 30 30 10 00 00 30 30 30 10 00 00 30 30 30 10 00 00 30 30 30 10 00 00 30 30 30 10 00 PHARMACOLOGY & DRUG DELIVERY Subcode: MLPE54 Prerequisite: Nil Course Coordinator(s): Dr.N.Sriraam ,Mrs. Supriya Babu Course objectives: 49 Credits: 3:0:0 Contact Hours: 42 1. 2. 3. 4. To understand the basics of pharmaco dynamics and kinetics To study pharmacology of the diseases To understand the drug disperse systems To apply various formulation methods Course contents: UNIT I PHARMACODYNAMICS AND PHARMACOKINETICS: Drug metabolism, pharmacokinetic action of drugs in human bodies, Dynamics of Drug Absorption, Distribution, Action, and Elimination, toxic, adverse effects. UNIT II Diseases and Drugs: Study of the pharmacology of the diseases and drugs used with mode of action especially of diabetes, vasoactive peptides, chemotherapy, hypertension, myocardial ischemia and inflammation. UNIT III Drug disperse systems: drug emulsions; drug suspensions; applications of disperse systems in delivery of pharmaceuticals; pharmaceutical gels, Diffusional system, Fick's law of diffusion, ransdermal delivery, ocular delivery and intra-uterine system. UNIT VI Formulation methods: principles, technology and manufacture of sustained drug delivery systems and applications to therapeutic delivery systems designed to release a specific quantity of drug at controlled rates; modified-release by coating: enteric and other coated tablets, particles and other systems. UNIT V Polymers & Release pattern: types of polymer, pharmaceutical polymers, NDDS models, osmotic pumps, Controlled release, delayed release, Sustained release etc., order of release. Oral controlled DDS, factors affecting controlled release. Text Books: 1. Bertram.G.Katzung, Susan.B.Masters, Anthony.J.Trevor (2009). Basic and Clinical Pahrmacology, 11th edition, Mc.Graw Hill. 2. H. C. Ansel, N. G. Popovich and L. V. Allen, (1999) Pharmaceutical Dosages Forms and Drug Delivery Systems, 6th ed, Williams & Wilkins. 3. K. B. Sloan (Ed), (1992) Prodrugs, Topical and Ocular Drug Delivery, Marcel Dekker Inc. Reference Books 1. Brunton LL, Lazo JS, Parker KL, Buxton ILO, Blumenthal D: Goodman & Gilman's The Pharmacological Basis of Therapeutics. Mc Graw Hill Medical. 11th ed. 2008. 2. Vasant. V. Ranade, Mannfred. A. Hollinger. Drug Delivery Systems. CRC Press, London. 2nd edition, 2005. Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: On completion of this course , the students should be able to : 1) Understand the basic foundations of pharmacology and drug delivery (pos: a,d,f,i) 2) identify mode of action on the drugs (pos: c,k) 3) formulate the various drug delivery methods (pos: j,k) 50 Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 20 35 15 10 10 10 HOSPITAL MANAGEMENT Subcode: MLPE55 Prerequisite: Nil Course Coordinator(s): Mrs.Prabha Ravi, Mrs. Prabhu Ravikala Vittal 51 Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. A better understanding of the involvement of management concepts in running a hospital 2. An insight into effective Human resource management in hospitals 3. Emphasis of manpower planning & recruitment process followed in hospitals 4. Understand the organizational development concepts and the importance of communication in a hospital 5. A brief analysis of counseling and biomedical waste management in hospitals Course contents: UNIT I INTRODUCTION TO HOSPITAL MANAGEMENT & ADMINISTRATION: Introduction, definition, classification, nature and scope of a hospital, difference between a hospital and an industry, functions of a hospital, hospital ethics, leadership, challenges in hospital administration, administrative conditions in hospitals, branding emotions, succession planning, feedback in planning, branded benefits UNIT II HUMAN RESOURCE MANAGEMENT IN HOSPITALS: Introduction, nature/characteristics & assumptions, fundamental principles, utilization factors, outsourcing, retention of top performers, characteristics of HR management, development & personal management, functions and importance of HR management, machines v/s human resources in hospitals, causes for poor HR management, good HR practices, UNIT III MAN POWER PLANNING: introduction, nature & scope of man power planning, need for man power planning, Benefits of manpower planning, objectives of manpower planning, manpower planning steps, work load ratio RECRUITMENT: introduction, recruitment, selection, induction, confirmation, probation & termination UNIT IV ORGANIZATIONAL DEVELOPMENT & MANAGEMENT BY OBJECTIVES ( MBO ): nature & scope, goals and characteristics, phases and limitations, definition & need for MBO, establishment of objectives, appraisal interview, practice, limitations and advantages of MBO COMMUNICATION IN HOSPITALS: Introduction, nature and scope, purpose, barriers, planning communication, effective communication, directions, styles and modes of communication UNIT V COUNSELING IN HOSPITALS: Introduction, nature and scope, role of listening, counseling service, effective listening, types, techniques and functions of counseling 52 BIOMEDICAL WASTE MANAGEMENT IN HOSPITALS: Introduction, environmental act 1986, hazardous waste rules 1989, the municipal solid waste rules 2000, the Bio-medical waste rules 2000 Text Books: 1. D K Sharma & R C Goyal, Hospital Administration & Human Resource Management, PHI 5th edition (2013) 2. A V Srinivasan, Managing A Modern Hospital, SAGE publications, 2nd edition (2008) Reference Books: 1. Robert Carroll, Risk Management for Healthcare Organizations, Wiley Publications, 2009 edition 2. Kenneth G Simone, Hospitalist recruitment & Retention, Wiley Publications, 2010 edition Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Reminisce the basics of management principles to a hospital administration (pos: a,c,e,i,j) 2. Comprehend the various approaches involved in human resource management in hospitals (pos: f,I,k) 3. Incorporate the concepts of manpower planning and recruitment process in hospitals (pos: a,c,e,i) 4. Analyze the factors involved in the development of a hospital as an organization 5. Realize the applications of communication & counseling in hospitals and accent the biomedical waste management rules in hospitals (pos: a,h) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1,2, 3 ,4 and 5 answer scripts 1 and 2 answer scripts 1,2, 3 ,4 and 5 Answer scripts 1,2, 3 ,4 and 5 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2, 3 ,4 and 5 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand 20 35 20 35 20 35 20 35 20 35 53 Apply Analysis Evaluate Create 15 10 10 10 15 10 10 10 15 10 10 10 DIGITAL VIDEO PROCESSING Subcode: MLPE56 Prerequisite: Nil Course Coordinator(s): Dr.C.K.Narayanappa , Mr. Basavaraj Hiremath 15 10 10 10 15 10 10 10 Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. Know the basic features of analog and digital video standards 2. Discuss the different time varying image formation models 3. Describe the various spatio-temporal sampling structures and their conversion for high-definition television, standarddefinition television, videoconferencing and videophones. 4. Study the image-plane motion (2-D motion) and object –motion (3-D motion) estimation. Course contents: UNIT – I Introduction: Analog video, Digital Video, Digital Video processing UNIT – II Time Varying Image Formation Models: 3D motion models, geometric image formation, photometric image formation, observation noise UNIT – III Spatio – Temporal Sampling: sampling for analog & digital video, 2D rectangular sampling, 2D periodic sampling, 3D sampling, reconstruction UNIT – IV Sampling Structure Conversion: Sampling rate change for 1D signals, sampling lattice conversion UNIT - V Optical flow methods: 2D motion v/s apparent motion, 2D motion estimation, methods using the optical flow equation Text Book(s): 1. Digital Video Processing, A Murat Tekalp, Prentice Hall Signal Processing Series ISBN;0-13-190075-7, 1995 Reference Book(s): 1. Handbook of Image & Video Processing, AL Bovik, 2 nd Edition, Academic Press, ISBN:0-12-119790-5, 2000 54 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: The students should be able to 1. Demonstrate sufficient understanding of theory on analog and digital video standards(pos: a,k) 2. Analyse the sampling structures for suitable video applications (pos: a,b,e) 3. Select the suitable technique to evaluate motion estimation in different video application (pos: e,k) Assessment and Evaluation vis-à-vis Course outcomes : To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students SEE Standard examination Students feedback Max Marks Evidence collected Course Outcomes Blue books 1,2 and 3 answer scripts 1 and 2 answer scripts 1, 2 and 3 Answer scripts 1, 2 and 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others Indirect Assessment Methods Direct Assessment Methods What - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 and 3, Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 30 30 20 10 10 0 20 30 10 20 20 0 20 20 20 30 10 0 0 0 30 40 30 0 20 30 10 30 10 0 OPEN ELECTIVES 55 MEDICAL INSTRUMENTATION Subject code: MLOE01 Credits: 3:0:0 Pre-requisite: nil Contact hours : 42 Course Coordinator(s): Mrs. Supriya Babu , Mrs. Prabha Ravi Course Objectives 1. To provide an overview of instrumentation systems used in clinical medicine and biomedical research. 2. To introduce students to biomedical measurements and provide necessary foundations of electronics. 3. To learn the principles and practices of measurements in the hospital, clinical chemistry laboratory as well as in cardiology, radiology, and other clinics. 4. To emphasize the importance of electrical safety in biological measurements. UNIT – I Measurement systems: Introduction to biomedical engineering, the need for bioinstrumentation, instrumentation system, system characteristics, Errors in measurements, statistics. Basic concepts of Electronics: Electronic components and circuit analysis, Amplifiers, Filters, ADC & DAC, Digital signal processing, microcomputers, software and programming languages, display devices, recording devices. UNIT – II Clinical lab Instruments: Spectrophotometry, oxygen saturation, bilirubin, lactate, creatinine, urea, Amperometric Biosensors for oxygen and glucose, Flame Photometry, Mass Spectrometry, Carbon dioxide concentration measurement by infrared transmission spectroscopy, Nitrogen by emission Spectrometry, Drugs by Flurometry and Chromatography, Electrophoresis, DNA sequencing. UNIT – III Diagnostic Instruments: Cell potential, Brain, EEG & evoked potentials, Brain imaging: X-ray, CT, MRI. Nuclear imaging: SPECT, PET, Bio-magnetism. Eye- ERG, EOG & visual field, Ears & Audiometry, Muscles. UNIT – IV Heart & Circulation: Cardiac anatomy & physiology, Cardiac bio-potentials, Cardiac pressures, cardiac output, Radionuclide angiography, Cardiac sounds, myocardial viability, circulation, blood flow, blood pressure, vessel distension, vessel volume flow. UNIT - V Body Temperature, heat, fat & movement measurements: Regulation of body temperature, clinical temperature measurement, Measurement of body heat-calorimetry, Measurement of body fat, Measurement of body movement. Electrical safety: Physiological effects of electricity, important susceptibility parameters, distribution of electric power, macroshock hazards, microshock hazards, electrical safety codes & standards, basic approaches to protection against shock, equipment design, electrical safety analyzers, tests of electric appliances. Text Books: 1. Bioinstrumentation by John G. Webster, John & Wiley publications- 2009. 2. Medical Instrumentation – applications & Design by John G. Webster, John & Wiley publications- 2009 Reference Book;: 1. Biomedical Instrumentation & Measurements, 2e, PHI/Pearson Education by Cromwell et. al.(2011) Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: The students should be able to 1. Demonstrate an understanding of the biomedical instrumentation principles used for imaging and clinical diagnostics. (POs: a, k) 2. Appreciate the linking of the engineering concepts of their respective branch of study to development of Medical Devices. (POs: a, h) 56 3. Interact in multi-disciplinary teams. (POs: d, ) Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessmen t Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Students End of course survey Evidence collected Course Outcomes Blue books 1,2 & 3 answer scripts 1,2 & 3 answer scripts 1,2 & 3 Answer scripts 1,2 & 3 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course End of course 100 Others SEE Max Marks - Feedback forms - Questionnaire 1,2 & 3 Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember 30 30 30 20 30 Understand 40 40 40 20 40 Apply 20 20 20 40 20 Analysis 10 10 10 20 10 Evaluate 00 00 00 00 00 Create 00 00 00 00 00 BIOMECHANICS Subject code: MLOE02 Credits: 3:0:0 57 Pre-requisite: nil Course Coordinator(s): Mr. Sanjay H.S ,Dr.N.Sriraam Contact hours : 42 Course Objectives 1. Reminisce the application of mechanical concepts in healthcare 2. Analyze the composition of the blood and its importance from the view of fluid mechanics 3. Understanding of the working of human body from a mechanical perspective 4. Appreciate the importance of biomechanics in the field of sports 5. Accent the ergonomical aspects and relate the same to biomechanics UNIT I INTRODUCTORY BIOMECHANICS: fundamental of force, Types of forces, Newton Laws, moment, conservation of energy, statics, Definitions -Stress and strain, Work and Energy, statics, Dynamics, kinetics and kinematics. Need for study of biomechanics – problem solving approach - Scope of mechanics in Physiology and Medicine – general constitutive equation – flow properties of blood. UNIT II KINETICS AND KINEMATICS: Definition - kinetics & kinematics – linear, angular and general motion – rigid body mechanics – mathematics of dynamics – linear & angular kinematics – mathematics of angular motion. UNIT III RESPIRATORY MECHANICS: Alveoli mechanics, Interaction of Blood and Lung P-V curve of Lung: Breathing mechanism, Airway resistance, Physics of Lung diseases UNIT IV SOFT TISSUE MECHANICS: Pseudo elasticity, non-linear stress-strain relationship, Viscoelasticity, Structure, function and mechanical properties of skin, ligaments and tendons. UNIT V ORTHOPEDIC MECHANICS: Mechanical properties of cartilage, diffusion properties of Articular cartilage, mechanical and viscoelastic properties of bone, Mechanics of elbow, shoulder and knee, lubrication of joints. Text Books: 1. Nihat Ozakya, Margareta Nordin, “Fundamentals of Biomechanics” VANNOSTRAND REINHOLD, Newyork (2013) 2. Y. C. Fung, “Biomechanics- Mechanical properties of living tissues”, 2nd ed, Springer-Verlag, 1993. Reference Books: 1. Silver Frederick H. “Biomaterials, Medical Devices & Tissue Engineering” Chapman & Hall, London, 1994 2. D. O Cooney, “Biomedical engineering Principles”. Marcel Dekker, NewYork, 1976. 3. Susan J.Hall, “Basic Biomechanics”, Vth ed., McGrawHill, 2006 4. Dhanjoo N. Ghista, “Orthopaedic Mechanics”, Academic Press, 1990 5. Dhanjoo N. Ghista, “ Biomechanics of medical devices”, Marcel Dekker, 1980 Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: student will be able to 1. Recall the basic mechanical concepts to realize the working of a human body from a mechanical perspective (pos; a,b,e,) 2. Interpret the fluid mechanics concepts to realize the functioning of various fluids present in human body (pos: a,e) 3. Understand and apply the basics of biomechanics to illustrate the biomechanics of the human body (pos: a,c,i) 58 4. Correlate the biomechanical aspects of human body to evaluate various factors involved in sports and ergonomics (pos; h,i,j) Assessment and Evaluation vis-à-vis Course outcomes : What To whom When/ Where Max Evidence Contributing to (Frequency in the marks collected Course Outcomes 30 Blue books 1, 2,3,4 Once 10 Answer sheets 1, 2 Once 10 Answer sheets 2 and 3 100 Answer scripts 1, 2, 3, 4 - Feedback forms -- - Question-naire -- Direct Assessment Methods course) C Internal Thrice(Average of I assessment the best two will be E tests computed) Surprise test Students Case study S E Methods Assessment Indirect E End of course Standard (Answering 5 of 10 examination questions) Middle of the Students feedback course Students End of course End of course survey Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS 1 2 Remember Understand Apply Analysis Evaluate Create 30 30 20 20 0 0 30 30 20 20 0 0 30 30 20 20 0 0 30 30 20 20 0 0 59 30 30 20 20 0 0 SEE 30 30 20 20 0 0 HOSPITAL MANAGEMENT Subject code: MLOE03 Credits: 3:0:0 Pre-requisite: nil Contact hours : 42 Course Coordinator(s): Mrs. Prabha Ravi , Mr. Sanjay H.S Course objectives: 1. A better understanding of the involvement of management concepts in running a hospital 2. An insight into effective Human resource management in hospitals 3. Emphasis of manpower planning & recruitment process followed in hospitals 4. Understand the organizational development concepts and the importance of communication in a hospital 5. A brief analysis of counseling and biomedical waste management in hospitals Course contents: UNIT I INTRODUCTION TO HOSPITAL MANAGEMENT & ADMINISTRATION: Introduction, definition, classification, nature and scope of a hospital, difference between a hospital and an industry, functions of a hospital, hospital ethics, leadership, challenges in hospital administration, administrative conditions in hospitals, branding emotions, succession planning, feedback in planning, branded benefits UNIT II HUMAN RESOURCE MANAGEMENT IN HOSPITALS: Introduction, nature/characteristics & assumptions, fundamental principles, utilization factors, outsourcing, retention of top performers, characteristics of HR management, development & personal management, functions and importance of HR management, machines v/s human resources in hospitals, causes for poor HR management, good HR practices, UNIT III MAN POWER PLANNING: introduction, nature & scope of man power planning, need for man power planning, Benefits of manpower planning, objectives of manpower planning, manpower planning steps, work load ratio RECRUITMENT: introduction, recruitment, selection, induction, confirmation, probation & termination UNIT IV ORGANIZATIONAL DEVELOPMENT & MANAGEMENT BY OBJECTIVES ( MBO ): nature & scope, goals and characteristics, phases and limitations, definition & need for MBO, establishment of objectives, appraisal interview, practice, limitations and advantages of MBO COMMUNICATION IN HOSPITALS: Introduction, nature and scope, purpose, barriers, planning communication, effective communication, directions, styles and modes of communication UNIT V 60 COUNSELING IN HOSPITALS: Introduction, nature and scope, role of listening, counseling service, effective listening, types, techniques and functions of counseling BIOMEDICAL WASTE MANAGEMENT IN HOSPITALS: Introduction, environmental act 1986, hazardous waste rules 1989, the municipal solid waste rules 2000, the Bio-medical waste rules 2000 Text Books: 1. D K Sharma & R C Goyal, Hospital Administration & Human Resource Management, PHI 5th edition (2013) 2. A V Srinivasan, Managing A Modern Hospital, SAGE publications, 2nd edition (2008) Reference Books: 1. Robert Carroll, Risk Management for Healthcare Organizations, Wiley Publications, 2009 edition 2. Kenneth G Simone, Hospitalist recruitment & Retention, Wiley Publications, 2010 edition Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Reminisce the basics of management principles to a hospital administration (pos: a,c,e,i,j) 2. Comprehend the various approaches involved in human resource management in hospitals (pos: f,I,k) 3. Incorporate the concepts of manpower planning and recruitment process in hospitals (pos: a,c,e,i) 4. Analyze the factors involved in the development of a hospital as an organization 5. Realize the applications of communication & counseling in hospitals and accent the biomedical waste management rules in hospitals (pos: a,h) Assessment and Evaluation vis-à-vis Course outcomes : Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Evidence collected Course Outcomes Blue books 1,2 3,4 & 5 answer scripts 1 and 2 answer scripts 1,2 3,4 & 5 Answer scripts 1,2 3,4 & 5 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks Indirect Assessment Methods 2 & 3, Delivery of the course 1,2 3,4 & 5 Students Effectiveness of End of End of course survey Questionnaire Delivery of course instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Students feedback Bloom Level T1 T2 T3 61 - Feedback forms OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 30 20 10 10 10 20 30 20 10 10 10 20 30 20 10 10 10 30 40 10 10 20 30 20 10 10 10 INTELLECTUAL PROPERTY RIGHTS & MEDICAL ETHICS Subcode: ML801 Credits: 3:0:0 Prerequisite: Nil Contact Hours: 42 Course Coordinator(s): Mrs.Prabha Ravi , Mrs. Supriya Babu Course objectives: 1. To understand the basic concepts of IP and its associated rights, forms of IP. 2. To get insight into the importance of innovation and its applicability in serving society. 3. To get awareness about the protections given to the mental labor put forth by individuals in various forms of IP 4. To know about the basic legal aspects of IP & basic ethics and behavior of a biomedical engineer in the society Course contents: UNIT - I Basic principles of IPR laws: History of IPR-GATT,WTO,WIPO & TRIPs, Role of IPR in Research & Development & Knowledge era, Concept of property, Marx’s theory of property, Constitutional Aspects of Intellectual property, Different forms of IPR – copyright, trade mark, Industrial Designs, Layout designs of Integrated circuits, Patents, Geographical Indications, Traditional Knowledge, Plant varieties, Trade secrets UNIT – II Understanding Copyright Law: Evolution of copy right law in India, Justifications, Subject matter of copyright, Terms of protections, Concepts-originality/Novelty idea expression, Fixation & fair Use, Copyrights in software protection, Infringement of copyright and acquisition in Indian context. Case studies TRADE MARK- Introduction, Justification, Concepts of subject matter acquisition, Implication and benefits of registration terms of protection of Geographical indication of goods infringements of trade marks. Case studies UNIT – III Patent: Basic principles of patent laws, Historical background, Basis for IP protection, Criteria for patentability, Novelty, Utility and Inventive step, Non obviousness, Non Patentable inventions. Searching: Prior art, tangible Vs intangible prior art, search strategy, pre-grant and post-grant oppositions, grant or refusal of patents, infringement and prosecution in India, US and other countries, request for reexamination and revocation, terms of patents and patent renewal, Cost of getting and maintaining patens in India, US and other countries. Importance of patent search in research. 62 UNIT – IV Patent application procedure and drafting: Patent Drafting: Format, Provisional & Complete specifications. Scopes of inventions, description of invention, drawings, claims. Filing requirements: Forms to be sent, Comparison of Patentability in different countries, filing mechanism-through individual patent office. PCT route & claiming priority from either route. Industrial Designs: Introduction, Justification, Subject matter of design law definition, Excluded subject matter Law relating to industrial design and registration in India, Infringement of design rights. Semiconductor & IC Layout Designs: semiconductor topography design rights. Infringement, Case studies. UNIT – V Biomedical Ethics: Theory, principles, rules and moral decisions, Belmont report, the principles of biomedical ethics: respect for autonomy, voluntariness information and informed consent, competency, nonmaleficence, the rule of the double effect, befecience, paternalism, justice.Examples Text Book(s): 1. 2. 3. 4. 5. Prabuddgha Ganguli, “Intellectual Property Rights”, TMH Publishing Co. Ltd. 2001 Dr. B. L. Wadhera, “Intellectual Property Law Handbook, Universal Law Publishing Co. Ltd., 2002. Thomas T Gordon & Arthur S Cookfair “Patent Fundamentals for Scientists and Engineers”, CRC Press 1995. Course materials for one year P. G. Diploma in IPR from NLSIU, Bangalore by Prof. T. Ramakrishna. D.H. Lawerance, Chapter 2, Principles of biomedical ethics Jones & Bartlet publishers. (2013) Reference Book(s): 1. World Intellectual Property Organizations (WIPO) Handbook/ Notes Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Identify the importance of IPR in the Society.(pos: f) 2. Innovate & apply for patents in his/her area of interest. .(pos: f) 3. Apply for copyrights for the novel work executed and learn about design the Trade marks. .(pos: f) 4. Learning and to apply the basic ethics and behavior of a biomedical engineer in the society.(pos: h) Assessment and Evaluation vis-à-vis Course outcomes : Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination 10 10 End of course (Answer any 5 of 10 questions) 100 63 Evidence collected Course Outcomes Blue books 1,2 3,4 & 5 answer scripts 1 and 2 answer scripts 1,2 3,4 & 5 Answer scripts 1,2 3,4 & 5 30 Once Others SEE Max Marks Middle of the course Indirect Assessment Methods Students feedback - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1,2 3,4 & 5 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 20 20 20 10 10 20 20 20 20 10 10 20 20 20 20 10 10 10 30 40 20 - 20 20 20 20 10 10 MANAGEMENT & ENTREPRENEURSHIP Subcode: ML802 Prerequisite: Nil Course Coordinator(s): Prof. P.G.Kumaravelu , Mrs.Prabha Ravi Credits: 3:0:0 Contact Hours: 42 Course objectives: 1. To impart students with the knowledge of basic principles of management & entrepreneurship and to learn the importance of Planning, Organizing, staffing, directing and controlling. 2. To learn about the concepts of different styles of motivation, company leadership, power and authority 3. To know about the strategies of organization, organization design and structure and to measure organization effectiveness. 4. To learn and understand various institutional support for starting a small scale industry & preparation of a project report Course contents: UNIT-I Introduction to Management: Evolution of management, managing in a global environment, ethics & social responsibility UNIT-II Planning & Organizing: Managerial planning & goal setting, strategy formulation & implementation, managerial decision making, designing adaptive organizations, managing change & innovation, human resource management UNIT - III Leading & Controlling: Leadership, motivation, communication, teamwork, managerial & quality control UNIT - IV Introduction to Entrepreneurship: Entrepreneurship revolution, evolution of entrepreneurship, corporate entrepreneurship, entrepreneurial individual, developing individual innovation, ethics & entrepreneurship UNIT - V Entrepreneurial Issues: Legal forms of entrepreneurial organization, legal environment, financial sources, strategic planning, challenges of entrepreneurial growth Text Book(s): 1. Principles of Management, Richard L Daft, Cengage learning, 2009 64 2. Entrepreneurship, by Kuratko & Hodgetts, Cengage Learning, 2009 Reference Book(s): 1. Management Fundamentals, Robers Lusier, Thomson Publications (2014) 2. Principles of Management, P C Tripathi & P N Reddy, Tata McGraw Hill Publications (2008) 3. Entrepreneurship Development, S S Khanka, S Chand & Co.(2006) Course Delivery: Regular black board teaching, Power point presentation/ group discussion/ interaction Course outcomes: 1. Analyse the functional areas of management and role of managers in managing people, processes and resources within a diverse organization. and analyze the nature, purpose & objectives of Planning, Organizing & Staffing. (pos: d,,i, k) 2. Analyze the nature & importance of Directing and Controlling in an Organization. (pos: d,,i, k) 3. Identify the importance of Entrepreneurship & role of Small Scale Industries in Economic Development (pos: d,,i, k) 4. Identify the Institutional support to start a Small Scale Industry & understand the Guidelines for preparation of a Project Report. (pos: d,,h,i,j k) .Assessment and Evaluation vis-à-vis Course outcomes : Indirect Assessment Methods Direct Assessment Methods What To whom Frequency Thrice (Average of the best two will be computed) Once Internal assessment tests CIE Others Students Standard examination Students feedback Evidence collected Course Outcomes Blue books 1, 2 ,3 & 4 answer scripts 1 and 2 answer scripts 1, 2 ,3 & 4 Answer scripts 1, 2 ,3 & 4 30 10 Once 10 End of course (Answer any 5 of 10 questions) Middle of the course 100 Others SEE Max Marks - Feedback forms Students End of course End of course survey Questionnaire 2 & 3, Delivery of the course 1, 2 ,3 & 4 Effectiveness of Delivery of instructions and Assessment methods Questions for CIE and SEE will be designed to evaluate the various educational components such as(%): Bloom Level T1 T2 T3 OTHERS SEE Remember Understand Apply Analysis Evaluate Create 20 20 20 20 10 10 20 20 20 20 10 10 20 20 20 20 10 10 10 30 40 20 - 20 20 20 20 10 10 65