SYLLABUS BIOLOGY 1107: Principles of Biology I Fall Semester 2008; (4:00-5:15PM Mon and Wed)-ITE C-80 Instructor: Dr. Thomas D. Abbott Office: Torrey Life Sciences, rm. 212 Phone: (860) 486-2939 E-mail: thomas.abbott@uconn.edu Office Hours: by appointment Materials you will need for this course (available at the UConn Co-op): • • Biology, 8th Ed., by Neil Campbell and Jane Reece. (2008) Benjamin Cummings. Try to read assignments before each lecture. Laboratory Manual: Biology 1107 Laboratory Manual, Fall 2008 edition • Safety splash goggles (3M brand, available in the “Supplies” section) • Lab coat: Purchase a lab coat (Tyvek brand, available in “Supplies” section) Computer and Internet Access: Access to the World Wide Web is required. Computers are available at the Computer Center, Residential Life, University Library, and other locations on campus. Course information will be posted on your HuskyCT website, which is accessible with your net ID. You will have TWO HuskyCT websites for Bio 1107 – one specifically for Lab Grades, listed on the HuskyCT page for your lab section and the other, your HuskyCT lecture page, for Course materials, including lab materials. Exam grades will be posted to your HuskyCT lecture section page. HuskyCT is accessed at http://huskyct.uconn.edu and help is available at http://lrc.uconn.edu/ or by calling 486-1187. Exams and Grades: Exam dates: There will be four exams, each covering 1/4 of the course material. The fourth exam is the final exam and is not cumulative. Exams are held in the lecture room. Exam 1: Monday, September 22 Exam 2: Monday, October 13 Exam 3: Monday, November 10 1 Exam format, content and point value: Exams will consist of 50 questions in multiplechoice format. Students must bring two #2 pencils to each exam. *Exams will be primarily based on the lectures, but may also include material from assigned text readings and the study guides, according to the discretion of each lecturer. The average of the four exam scores will comprise 65% of your course grade. Exam grades will be scaled if necessary. These scales are only advisory in nature -- the only scaling that counts towards your actual course grade is the final scaling carried out after the final exam. Your performance in the lab will contribute the remaining 35% of your course grade. Exam location: All exams during the semester will be held in the lecture classroom. Unless otherwise noted, final exam location may differ, but will be announced towards the end of the semester. Exam times: During the semester, exams are held at regular class time, 4:00-5:15PM. Another class uses the same room after our class, so it is not possible to have extra time at the end of the class period. Exams for students with special needs: If you have a documented learning disability, please see the instructor at least one week before the first exam and bring any paperwork you were given by CSD. Also, if English is not your native language, and you wish to discuss the possibility of extra time for exams, please see the instructor before the first exam. Makeup Exams: Makeup Exam Policy: Makeup exams are available only to students who have a legitimate excuse for missing an exam, such as illness, scheduled job interview out of town, athletic team event out of town, death in the immediate family, etc. If you know in advance that you must miss an exam, see the instructor prior to this date and bring documentation to support your anticipated absence. If you miss an exam unexpectedly because of last minute illness or accident, contact the instructor when you return to campus (or by phone or e-mail if you will be away for some time) and provide documentation of your situation. Makeup Exam Dates: Makeup exams will be given on the following days for those students who missed the scheduled exam and who have received permission to make up the exam. Makeup exams may include short-answer, short essay, and/or multiple-choice questions. Makeup for Exam 1: Wed, 9/24 at 5:30PM in Torrey Life Science Rm. 212 Makeup for Exam 2: Wed, 10/15 at 5:30PM in Torrey Life Science Rm. 212 Makeup for Exam 3: Wed, 11/12 at 5:30PM in Torrey Life Science Rm. 212 2 Laboratories: Laboratory start date: Labs begin the second week of classes, Tuesday, [9/2 - 9/5]. Dissection Policy: The use of preserved and dissected animals is required for this course. If you are unwilling to participate in these exercises you should drop this course. Laboratory Grading Policy: This will be presented in your first lab section and is given in the lab syllabus (posted on HuskyCT). Attendance Policy: Attendance in lab is mandatory. You must attend the lab section for which you are registered. If you wish to change lab sections, you must do this through the Add-Drop system; your instructors have no control over the availability of seats in lab. There is usually some turnover in lab schedules during the first week, so check the PeopleSoft computer system frequently to see if a space has opened up. If you cannot find an available lab seat that matches your schedule, you will not be able to take the course at this time. The MWF 9 a.m. lecture is linked with lab sections 01-13, 28, and 30-32. The MW 4:00 p.m. lecture is linked with lab sections 14-27 and 29. You must attend the lecture and lab for which you are registered. Even though labs are identical in content, it is not possible for us to "mix and match" by allowing students in one lecture section to attend labs linked to the other lecture section. Makeup Policy for Labs: All labs are changed at the end of every week, so it is not possible to make alternate arrangements for lab once the week has passed. If you must miss a lab for a valid reason, contact both of your TAs (Teaching Assistants) ASAP). The lab schedule and TA contact information is accessible on the course website. You must complete the laboratory activities during scheduled lab times to receive credit. Missing more than 3 laboratory periods, for any reason (including illness), makes you ineligible to receive laboratory credit. This will result in a final COURSE grade of “F” even if your grades are otherwise adequate to pass the course. If you find yourself in the situation of missing more than three labs, you should contact the course instructor and/or drop the course and retake it at a later date when you can complete the laboratory portion. For further details, refer to the laboratory policies page, which will be posted on HuskyCT along with the lab syllabus. 3 Academic Misconduct Policy: UConn's Policy: A fundamental tenet of all educational institutions is academic honesty; academic work depends upon respect for and acknowledgement of the research and ideas of others. Misrepresenting someone else's work as one's own is a serious offense in any academic setting and it will not be condoned. Academic misconduct includes, but is not limited to the following: • Providing or receiving assistance in a manner not authorized by the instructor in the creation of work to be submitted for academic evaluation (e.g. papers, projects, and examinations). • Any attempt to influence improperly (e.g. bribery, threats) any member of the faculty, staff, or administration of the University in any matter pertaining to academics or research. • Presenting as one's own work the ideas or words of another for academic evaluation. • Doing unauthorized academic work for which another person will receive credit or be evaluated. • Presenting the same or substantially the same papers or projects in two or more courses without the explicit permission of the instructors involved. A student who knowingly assists another student in committing an act of academic misconduct shall be equally accountable for the violation, and shall be subject to the sanctions and other remedies described in The Student Code at http://www.dos.uconn.edu/ Lecture Schedule Part I: Cells-Molecules-Energy-Transport-DNA Date Mon 08/25 Lecture Topics Chemistry of Life (I): Chemical context of life Importance of water to life and pH Carbon compounds and Molecular diversity Text Readings pp 30-43 pp 46-54 pp 58-66 Wed 08/27 Chemistry of Life (II): Carbohydrates, lipids, proteins and nucleic acids pp 68-89 Mon 09/01 Labor Day: No classes Wed 09/03 Prokaryotes, Eukaryotes and Viruses: Structure and Basic Physiology 4 pp 556-564 pp 94-122 pp 381-386 Mon 09/08 Metabolism (I): Principle of thermodynamics enzymes and enzymatic reactions Wed 09/10 Metabolism (II): Glycolysis, Citric Acid Cycle, and electron transport pp 162-182 Membranes and Transport: Phospholipid bilayers and diffusion Cell Comunication: Signal Transduction pp 125-139 pp 206-217 Mon 09/15 pp 142-159 Wed 09/17 Cell Cycle and Mitosis: Cell Division pp 228- 243 Meiosis and Sexual Reproduction pp 2248-257 _______________________________________________________________________________ Mon 09/22 Exam I (Covers Topics 8/25-9/15) Wed 09/24 Chemical Identity of Genetic Materials: DNA structure DNA Replication: Mon 09/29 Wed 10/01 Mon 10/06 Wed 10/08 Protein Synthesis: How DNA is used to construct a polypeptide Regulation of Gene Expression in Prokaryotes and Eukaryotes: How gene expression is turned on and off pp 305-311 pp 312-323 pp 325-344 pp 351-364 Basic Genetics: Inheritance, genotypes Phenotypes and gene-to-gene interaction pp 262-274 DNA Technology: Current techniques used to study the sequence, expression and function of a gene pp 396-423 Genomics: Bioinformatics, transposable elements and multigene families pp 426-446 Mon 10/13 Exam II (Covers Topics 9/17-10/08) ______________________________________________________________________ 5 Part II. Animal Structure and Function Date Lecture Topics Text Readings Wed 10/15 Intro to animal structure and function: Body Plans. Tissues, organs, organ systems homeostasis and bioenergetics. pp 852-872 Mon 10/20 Movement and Locomotion. Motor mechanisms. Musculoskeletal systems. Mechanism of muscle contraction. pp 1105-1117 Wed 10/22 Nutrition I. Types of digestive systems. Stages of food processing Nutrition II. Vertebrate digestive system. Digestive specializations. Hormones and enzymes. pp 875-883 Circulation I. Types of transport systems. Mammalian circulatory system: design, heart. Circulation II. Blood Vessels Blood composition pp 898-905 Mon 10/27 pp 884-890 pp 906-910 pp 911-914 Wed 10/29 Cardiovascular Diseases Respiration. Factors controlling diffusion rate. Adaptations for gas exchange. Exchange and transport of gases. Control of breathing. pp 914-915 pp 915-927 Mon 11/03 Thermo & Osmoregulation. Regulation of temperature. Osmoregulatory systems in different habitats: marine, freshwater, terrestrial. Excretory Systems. Adaptations. Production of urine by the kidney. Hormonal regulation. pp 954-964 Wed 11/05 Reproduction I. Methods of asexual and sexual reproduction. Male reproductive system. Female reproductive system. Reproduction II. Mammalian Reproduction and the Female reproductive cycle. pp 964-968 pp 997-1006 pp 1007-1012 __________________________________________________________________ Mon 11/10 Exam III (Covers Topics 10/13-11/03) 6 Wed 11/12 Mon 11/17 Wed 11/19 Animal development I. Fertilization, gastrulation, organogenesis Animal development II. Morphogenesis: Cytoplasmic Determinants and Cell-Cell induction pp 1021-1030 Nervous system I. Neurons and glia, Action potentials, Synapses, neurotransmitters through biogenic amines Nervous system II. Organization of the vertebrate nervous system. pp 1047-1061 Chemical signals I. Types of chemical communication. Mechanisms of hormone action. Chemical signals II. Endocrine glands: pituitary, thyroid, pancreas, adrenals, gonads. pp 975-984 pp 1030-1044 pp 1064-1069 pp 984-994 11/23 11/30 Thanksgiving Break Mon 12/01 Defenses against Disease I. Lymphatic System Non-specific defenses pp. 910-911 pp 930-936 Wed 12/03 Defenses against Disease II. Specific defenses: pp 936-951 Exam #4 - Final Exam (Covers Topics 11/05-12/03) Date and time to be announced. Attention Students. Final exam week for Fall 2008 takes place from Monday, December 8, through Saturday, December 13. Students are required to be available for their exam during that time. Students must visit the Dean of Students Office if they cannot make their exam. The DOS will give the student his or her instructions thereafter. Please note: vacations, previously purchased tickets or reservations, weddings (unless part of the wedding party), and other large or small scale social events, are not viable excuses for missing a final exam. Please contact the Dean of Students office with any questions. Thank you in advance for your cooperation.” Have a Great Semester! 7