have become unwieldly monsters hijacked by the financially motivated. A forthcoming international conference on HIV and AIDS is a case in point. Registering participants are limited to one abstract. Submission of the abstract requires the payment of the registration fee (445). Abstracts must be submitted by February 1. The deadline for notification of abstract acceptance is April 15. If the abstract is not accepted at this stage then only 50% of the fee is returnable. Telephone cancellations are not acceptable. Cancellation after May 1 leads to complete loss of registration fee. Why has this approach been taken? First, to increase the quality of abstracts by limiting to one per registration and discouraging poor quality submissions? Registrants, or those with a copy of the doubtless substantial abstract book(s), will be able to overall decide the quality. Second, to discourage submissions from poorly funded groups? Clearly there are many people who will only obtain funding on the basis of an accepted abstract. This is especially true of workers in the developing world. Third, to maximise income? Although conferences must make some profit if anyone is going to go to the trouble of organising them, the financial motive seems to overwhelm the scientific purpose of the event. What is true is that this will prove to be an enormous and well attended conference and it is likely that the costs involved (registration, travel, accommodation) will massively exceed the resources that are available biannually to many nations in Africa in their attempts to prevent and manage HIV disease. N French Medical Research Council, Research Programme on AIDS Virus Research Institute, PO Box 49, Entebbe, Uganda in Uganda, Birth dates and admission to medical school SIR--Boddi and colleagues have claimed in Nature’ that, in a group of 957 medical students in Florence, Italy, a significant excess was born during April to June. They interpreted the result in terms of "the importance of the seasons in the early development of the child", and hoped that "someone in the Southern Hemisphere will now analyse similar data, in order to confirm (or to confute) the ’spring advantage"’. Here I report being unable to confirm the effect they find, even in another and much larger European sample. We have collected extensive data on the selection of British medical students, studying those applying for admission in October, 1981,z 1986,’ and 1991.4 Season of birth did not differ between successful and unsuccessful applicants in any of the three cohorts (=0-931, 2-641, 0-939, respectively); the table shows data for all applicants. Nor did cohorts differ in season of birth (B=5-533), and the cohorts were therefore combined. The proportions of applicants in each season were compared with the proportion born during the same seaons in 1974,5 and show a highly significant difference from the expected numbers (X2=24’068, p<0-001). However, size of the effect is much smaller than-and the pattern is entirely different fromthat reported by Boddi’s group,’ with fewer students born in April to June, and the greatest numbers born in October to December. In Britain, schooling usually begins in September. The reported advantage for those born during autumn and winter is perhaps explained by a child born in autumn having spent a greater proportion of its total life in education than has a child born during the summer. 1 Bennett JR. Altruism and Scientific congress. Lancet 1996; 347: 377-78. Mental health research in Japan SIR-Takei p 523)’ is right to disclose the very low mental care research in Japan. Japanese funding for the health sciences has put heavy emphasis on "hard" medicine-such as development of medical instruments (endoscopy, computed tomography, and so on) and pharmaceuticals2-largely because their efficacy is easy to judge and their commercial prospects are biggest. Mental health has been generally neglected in Japanese society because the issue is kept out of the public eye.3 Since most psychiatric patients are confined to psychiatric units and do not commit any crimes, the public rarely gives thought to them and no organisation (governmental or otherwise) feels a burning need to support such studies. The financial situation of health research is even worse than portrayed because institutional overheads almost halve the amounts. In return for this charge, the institutions should support research by providing secretarial assistance, for example, but in practice hardly any support is available.2 Moreover, there is a risk of fraud in clinical trials because busy clinicians tend to rely on industry manpower to fill in case-report forms. In mental health research informed spending (Feb 24, This failure to replicate was originally sent to Nature, who declined to publish, with no reason given. That rejection must raise concerns about the probity of scientific publishing since, presumably, if an effect is interesting or important enough to publish in the first instance, then at least one refutation must also be of interest. on I C McManus Imperial College of Science, Technology and Medicine, Paterson Centre for Mental Health, London W2 1PD, UK 1 2 3 4 5 Boddi V, Brizzi E, Conti A, Gensini GF. Birth dates in Florence. Nature 1996; 379: 394. McManus IC, Richards P. An audit of admission to medical school: 1. Acceptances and rejects. BMJ 1984; 289: 1201-04. McManus IC, Richards P, Maitlis SL. Prospective study of the disadvantage of people from ethnic minority groups applying to medical schools in the United Kingdom. BMJ 1989; 298: 723-26. McManus IC, Richards P, Winder BC, Sproston KA, Styles V. Medical school applicants from ethnic minorities: identifying if and when they are disadvantaged. BMJ 1995; 310: 496-500. OPCS. Birth Statistics: review of the Registrar General on births and patterns of family building in England and Wales, 1974. London: HM Stationery Office, 1977: 17. may be ignored. restructuring of health-research funding in Japan is urgently needed, especially for studies in mental health. consent A Kyoko Imamura 4-3-10-102 1 2 3 Kamiyoga, Setagaya-ku, Tokyo 158, Japan Takei N. Funding of research in mental health care in Japan. Lancet 1996; 347: 523-24. Imamura K. A critical look at research in Japan. Lancet 1993; 342: 279-82. Imamura K. Mental health in Japan. Lancet 1995; 346: 509-10. 1120 Table: Season of birth of medical school applicants and entrants