UCL SCHOOL OF LIFE AND MEDICAL SCIENCES (SLMS) ISSUE 3 APRIL 2009 SLMS NEWSLETTER www.ucl.ac.uk/slms SLMS RESEARCH UCL Partners update New grant success SLMS EDUCATION MSc in Sports & Exercise Medicine UCL Health & Society Summer School SLMS News New tissue culture equipment in Cruciform labs SLMS People Interview with David Shanks SLMS Events Launch event of the UCL Centre for Stem Cells and Regenerative Medicine CONTENTS DEANS COLUMN 2 DEANS COLUMN 3 SLMS RESEARCH 3-5 MAJOR INITIATIVES 6 NEW GRANT SUCCESS 7-8 RESEARCH FOCUS 9-11RESEARCH NEWS 11-13RESEARCH HIGHLIGHTS 14SLMS EDUCATION 14 NEW GRADUATE OPPORTUNITIES 15-17EDUCATION NEWS 16SLMS NEWS 18-19SLMS NEWS ROUND UP 19 SLMS STUDENT NEWS 20SLMS PEOPLE 20-21 INTERVIEW PROFESSOR DAVID SHANKS 22-23NEW APPOINTMENTS 1 JANUARY – 28 FEBRUARY 2009 23 PEOPLE NEWS IN BRIEF 24EVENTS 24ACADEMIC EVENTS 24STEM CELLS AND REGENERATIVE MEDICINE LAUNCH EVENT Dear Colleagues By now most of you will be aware that the Department of Health granted UCL Partners (UCLP) the status of being one of the first Academic Health Science Centres in the country. The Partnership is one of just five bids which satisfied the Department of Health’s rigorous selection process, demonstrating that it possessed excellence in research, education and patient care. The Partnership will work towards delivering world-class research, education and patient care for the benefit of the local community, and then promote the application of discoveries in the NHS and around the world. Last month we held a number of open meetings to inform staff about this opportunity. But what impact will this partnership have on staff in the School? A detailed analysis (by Professor Byrne) is available in this newsletter. Progress continues with plans for the UK Centre for Medical Research and Innovation (UKCMRI), the partners are working together to determine the scientific direction of the Centre and the exact nature of the involvement of UCL staff. Over the last few months SLMS research has received significant coverage and has featured across web, print and broadcast media. 2 We are delighted to report that the History of Medicine podcasts have been a huge success, the series, Today’s Neuroscience, Tomorrow’s History, is top of the list of UCL iTunes downloads. In addition, staff in the Medical School have developed an e-Learning revision resource for final year MBBS students, the initiative has received positive feedback. There is no doubt that blended learning will increase in the coming months as staff begin to utilise the technology available. In the last newsletter we noted that plans were progressing for the UCL Education Deanery, after a lengthy consultation period the proposed format has changed somewhat but we are currently moving forward with a joint committee structure across the School. This newsletter contains an update from DoME on the MBBS and the postgraduate review. Kind Regards Professor Edward Byrne Dean of UCL Faculty of Biomedical Sciences and Head of UCL Medical School Professor Peter Mobbs Professor of Physiology and Dean UCL Faculty of Life Sciences The results of the first Newton International Fellowships have just been announced. The purpose of the scheme is to select the very best early stage post-doctoral researchers from all over the world, and offer support for two years at UK research institutions. UCL SCHOOL OF LIFE AND MEDICAL SCIENCES ISSUE 3 APRIL 2009 SLMS RESEARCH MAJOR INITIATIVES UCL Partners The Department of Health recently granted UCL Partners (UCLP) the status of being one of the first Academic Health Science Centres in the country. Professor Edward Byrne, Executive Dean of UCL Faculty of Biomedical Sciences, comments on this new era in university health service collaboration. The UK Government with the NHS recently completed a designation process for Academic Health Science Centres. The aim of this process, conducted with the help of an international jury, was to identify a small number of University/Health Partner Consortia which have the capacity and the ambition to compete internationally at the highest level as centres of innovation and excellence in health care. The very best academic activities in medical and health science and health delivery in North America are referred to as Academic Health Centres (AHSC) and this model has become increasingly prevalent for Centres of Excellence around the world, for example the Karolinska University and Hospital in Stockholm and the new developments in Singapore with merger of the National University Medical School and its key hospitals. The international jury were looking for evidence of major underpinning excellence in research and education relevant to health but also for a commitment to develop and improve processes which improve health outcomes in local communities in the United Kingdom within a relatively short time frame. Quite a number of University, Hospital Trust Partnerships applied for designation as AHSC and seven consortia were shortlisted. Eventually five were designated namely UCL Partners and the consortia centred around Imperial College, King’s College, Cambridge University and Manchester. The expectation is that with this designation, the academic Health Science Centres designated will make significant contributions to both medical research and education and to health outcomes in the United Kingdom. They will be beacons of excellence recognised internationally. Designation has been an extremely important process and achievement for the UCL Medical School and for the School of Life and Medical Sciences. Medical science at UCL has a rich history and represents a coming UCL SCHOOL OF LIFE AND MEDICAL SCIENCES together of a number of outstanding medical schools namely the Middlesex School, the Royal Free School, the UCLH School and four Postgraduate Institutes that were previously independent institutes of the BMA namely the Institute of Neurology, the Institute of Child Health, the Institute of Ophthalmology and the Eastman Dental Institute. These outstanding centres of medical research have long been affiliated with major hospitals and have stimulated excellence in clinical care. The Royal Free and UCL Medical School (now the UCL Medical School) has long been a collaboration between life scientists in the Faculty of Life Science and clinicians and clinical scientists in what was for many years the Faculty of Clinical Science at UCL. This alignment of clinical science with outstanding basic science has been one of the real strengths of medical science at UCL and has contributed to the leading place that UCL now enjoys in Europe in terms of medical and health research outputs. The Faculty of Life Sciences and what 3 is now the Faculty of Biomedical Sciences also underpin outstanding teaching activities both in the basic medical degree and in a range of taught postgraduate degrees. ISSUE 3 APRIL 2009 SLMS RESEARCH MAJOR INITIATIVES Together they support an outstanding graduate student programme with over a thousand PhD students enrolled. The development of a shared vision for teaching and research underpinning excellence of health care delivery under the auspices of UCL Partners will provide new opportunities for the great strengths in medical research and education in the UCL family to drive improvements in health outcome. This will include developing new educational approaches to meet needs in health leadership. A joint approach to education in many aspects of the post graduate arena will be developed between UCL and its healthcare partners. On the research side the opportunity is already being taken advantage of in many parts of the university to take basic science advances through a translational stage into the clinic and this will be accelerated. In addition, the rigorous scientific approach embraced by UCL and its key partners will be further strengthened ensuring a sound evidence base and aspiration to world class practice and clinical outcomes underpins all major activities. True excellence in education and in research will support and underpin clinical excellence and health outcomes. UCL Partners has been established with five core partners namely UCL itself, and four hospital trusts, UCLH, The Royal Free, Moorfields and Great Ormond Street Children’s Hospital. These core partners have been working for almost two years in developing plans for UCLP. A number of other members have 4 indicated a commitment to join UCLP including five primary health care trusts, four mental health trusts and a number of other major hospitals in our region. New academic members will include the School of Pharmacy and the School of Hygiene and Tropical Medicine which are independent colleges of the University of London. The capacity and excellence brought together by these partners is considerable as is the resultant opportunity. The aim will be to provide seamless links in education and research across the partnership. There is a firm ambition to improve health care outcomes at every level ranging from community services to outcomes in tertiary referral practice. evidence that partners have world class capacity in education and research which can underpin and improve clinical outcomes. New themes are currently being explored. The themes involve activities extending from the community to the hospital and bring together scientists across the breadth of UCL from both the Faculty of Life Sciences (FLS) and the Faculty of Biomedical Sciences (FBS). Theme leaders are in the process of being appointed who will have a high degree of responsibility in co-ordinating and leading large programmes in the agreed areas. UCL Partners as with other Academic Health Science Centres in the UK will be flag ships for medical research, education and treatment of patients in the United Kingdom. UCLP will compete internationally at the highest level and has the aim of being one of the outstanding Academic Health Science Centres in the world going ahead. It will be fully collaborative with other Academic Health Science Centres in London and elsewhere in the United Kingdom, leading health science for the UK. The brief is to improve health in our local communities underpinning an aspiration to excellence, patient safety in treatment pathways and in health outcomes. Health outcomes will be improved nationally both through the development of new innovations and through approaches that can be extended to other areas in the United Kingdom. International outcomes will be improved through the development of new discovery and innovation which will influence how patients are treated around the world. In addition, co-ordinating functions for strategic deliberation and planning will be developed under UCLP in the areas of research, education and clinical safety and outcomes. These will facilitate collegiate discussion and opportunities for collective planning. In developing partners a number of themes have been selected where there is an aspiration or existing UCL SCHOOL OF LIFE AND MEDICAL SCIENCES We all know the ancient Chinese curse “to live in a time of change” but for the UCL family at the moment change presents massive opportunity. There are major opportunities in the research area through the reorganisation and consolidation of activities in FLS and FBS with joint theme and platform development, in research more generally with opportunities offered by UCL’s collaboration in major new institute developments and the development of UCL Partners completes an essential part of the equation by consolidating the already strong links both between UCL and key hospital and health provider trusts and within the extensive health care family affiliated with UCL. These developments have attracted considerable attention internationally and provide a platform for ongoing success in the years ahead. ISSUE 3 APRIL 2009 SLMS RESEARCH SLMS allocates £7.8M CIF funding for technology platforms at UCL The Faculties of Biomedical and Life Sciences have combined their share of the 2008-2011 Capital Infrastructure Fund (CIF) allocation. A total of £7.8million has been dedicated to the Platform Technology Development initiative, led by Professor Salvador Moncada. Platform Technologies encompass genomics and genotyping, proteomics and biophysics, imaging, transgenics and biological services, biobanks, and the informatics systems required to support these technologies. Professor Moncada has chosen to stage a series of open calls for proposals over three years. “This will allow us to support and facilitate research and at the same time introduce some strategic thinking in the development of our combined infrastructure” said Professor Moncada. UCL Genomics has purchased a state-of-the-art genome analyser, the Roche GS-FLX, which complements the Illumina Genome Analysers based at the Cancer Institute, providing UCL with the largest next generation sequencing capability in London. Dr Mike Hubank, Scientific Director of UCL Genomics and a group leader at the Institute of Child Health says “The system allows us to study the complexity of genomic DNA at the level of the individual nucleotide, allowing us to rapidly and economically identify mutations responsible for disease in patients, to discover new disease genes at a rate never previously possible, and to study the complexity of bacterial populations with astonishing resolution The acquisition of this platform will allow UCL to continue at the forefront of genome discoveries in the years to come.” Several Imaging labs have benefited from this particular CIF round, including Professor David Becker who runs the Live Cell Imaging Facility in the Dept. of Cell and Developmental Biology. Prof Becker says “The addition of lifetime and TIRF imaging has enabled us to examine the dynamics of a variety of cellular processes, which was not possible with our existing equipment. Now we have a TIRF imaging system we will be able to image the dynamics of a cell’s cytoskeleton, under different conditions, whilst it is migrating forward or growing out neurites.” UCL SCHOOL OF LIFE AND MEDICAL SCIENCES In another example of supporting innovation in Imaging, Prof Angus Silver (Neuroscience, Physiology and Pharmacology) has received funding to develop a new type of 2-photon microscope capable of functional imaging in 3 dimensional space at high speed with submicron resolution. “This novel technology is expected to help UCL neuroscientists to better understand how networks of neurons in the brain process information.” Dr Juan-Pedro Martinez-Barbera runs the ES targeting facility at the Institute for Child Health, which is one of the Transgenics platform labs receiving funds to develop UCL’s capability for generating transgenic mouse strains. “This investment is expected to have a favourable effect on the application we have recently submitted to the Wellcome Trust with the main aim of establishing a central facility at UCL for the generation of genetically modified mice, as well as cryo-preservation and re-derivation of mouse lines.” The third and final call for proposals for CIF funding will be open from June 2009 to researchers based in SLMS. For information about the Platform Technologies initiative please contact the Coordinator Jacky Pallas (j.pallas@ucl.ac.uk). ISSUE 3 APRIL 2009 5 SLMS RESEARCH New grant success We are indebted to all our sponsors. Without their continuing support we would not be able to undertake world class research. Listed below are details of research projects above £500,000 with a start date of 1st January - 28th February. These awards, from a variety of sources, support a wide range of research across the School. SLMS Staff can obtain details of all awards on the School website: www.ucl.ac.uk/slms/research/current-projects. Professor Linda Franck UCL Institute for Women’s Health £ 500,000 NATIONAL INSTITUTE FOR HEALTH RESEARCH Patient Care Research and Innovation Centre: Providing the Infrastructure to Expand Patient Care Research at the UCLH/UCL CBRC Professor Jim Mallet UCL Division of Biosciences £ 513,501 BBSRC Genomic Analysis of Complex Speciation in Heliconius Dr Mala Maini UCL Division of Infection & Immunity £ 521,179 MRC Bim-Mediated Attrition of VirusSpecific CD8 T Cells in Chronic HBV Infection Professor Greg Towers UCL Division of Infection & Immunity £ 572,278 MRC Correlating Gene Expression Changes and Innate Immune Responses with Protective SIV Vaccination in Cynomolgus Macaques 6 Professor Francesco Muntoni UCL Institute of Child Health £ 576,399 MRC A Phase I/II Clinical Trial in Duchenne Muscular Dystrophy Using Systemically Delivered Antisense Oligonucleotides Dr Gareth Ackland UCL Division of Medicine £ 711,840 ACADEMY OF MEDICAL SCIENCES Fellowship - Academy of Medical Sciences Prof Stephan Beck UCL Cancer Institute £ 778,097 WELLCOME TRUST Epigenomics of Common Disease Professor Ian Jacobs UCL Division of Research Strategy (DORS) £ 797,000 MRC Pump-Priming Translational Research Initiative Professor Robin Weiss UCL Division of Infection & Immunity £ 815,930 MRC Humoral Immunity to Human Immunodeficiency Virus (HIV) Professor David Shima UCL Institute of Ophthalmology £ 883,231 GLAXO RESEARCH & DEVELOPEMENT LIMITED GSK Collaborative Agreement UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Professor Harry Hemingway UCL Division of Population Health £ 1,135,164 WELLCOME TRUST Higher Resolution Cardiovascular Epidemiology: Unique Insights from Linking the National Cardiac Event Register with Primary Care Records and Highly Phenotyped Cohorts Professor Linda Partridge UCL Division of Biosciences £ 1,295,343 MRC Fellowship - A Detailed Network of Transcriptome Regulation Associated With Life-Span Extension in Model Organisms Professor Mark Marsh MRC Laboratory for Molecular Cell Biology £ 1,588,091 MRC Fellowship - Cell Cycle Regulated Transcription and Control of Genome Integrity Professor Bill Richardson Wolfson Institute for Biomedical Research at UCL £ 1,874,619 MRC Stem and Progenitor Cells of the Postnatal CNS Professor David Miller UCL Institute of Neurology MULTIPLE SCLEROSIS SOCIETY OF GREAT BRITAIN £ 2,544,384 Translating new magnetic resonance imaging insights in to treatment options and clinical trial design in multiple sclerosis ISSUE 3 APRIL 2009 SLMS RESEARCH Research focus UCL study reveals therapists still offer treatment for homosexuality Researchers from UCL and St George’s, University of London have published a report which indicates that a significant minority of psychiatrists and therapists still attempt to help lesbian, gay and bisexual clients become heterosexual, despite a lack of evidence that such treatment is effective or even safe. The research, funded by the Wellcome Trust and published in the open access journal BMC Psychiatry, coincides with the researchers’ launch of the web site www.treatmentshomosexuality.org. uk. The aim of the web site is to raise awareness of this issue. It provides oral histories from lesbian, gay and bisexual people who have undergone treatment, and from professionals who developed and conducted such treatments. The researchers questioned more than 1,400 mental health professionals on whether they would attempt to change a client’s sexual orientation, if requested to do so. Although only one in twenty-five (4%) said that they would do so, one in six (17%) reported having assisted at least one client to reduce their gay or lesbian feelings, usually through therapy. There has been little or no decline in numbers treated over recent decades. “There is very little evidence to show that attempting to treat a person’s homosexual feelings is effective, and in fact it can actually be harmful,” says Professor Michael King, Professor of Primary Care Psychiatry at UCL Mental Health Sciences, “so it is surprising that a significant minority of practitioners still offer this help to their clients.” Professor King and his colleagues – Dr Glenn Smith (at the time of the study a Research Fellow at UCL Mental Health Sciences, now at Imperial College London) and Dr Annie Bartlett from St George’s – found that the reasons given by these psychiatrists and therapists for offering this kind of assistance ranged from the counsellor’s own moral and religious views on homosexuality to a desire to help patients who were suffering stress as a result of discrimination. There was also a degree of ignorance among the practitioners about the lack of evidence surrounding the efficacy of such therapies – in particular, that no randomised control trials showing that therapy is effective have ever been conducted. Research offers hope for early detection of ovarian cancer Preliminary results of a UCL-led investigation suggest that testing women for ovarian cancers may become a reality. Following the largest randomised trial of ovarian cancer screening to date, Professor Ian Jacobs (Dean of UCL Health Sciences Research and Director of the UCL Institute for Women’s Health), and Dr Usha Menon (Head of the UCL Gynaecological Cancer Research Centre), have published their findings online in The Lancet Oncology. The report, to be published in print in The Lancet Oncology’s April edition, indicates that two tests – a multimodal one involving a combined blood test and ultrasound, and a transvaginal ultrasound – are feasible on a large scale and capable of detecting early stage ovarian cancers, with almost half of all cancers detected in stages I (i.e. with the cancer confined to the ovaries) and II (i.e. the cancer UCL SCHOOL OF LIFE AND MEDICAL SCIENCES has spread beyond the ovaries, but is confined to the pelvic area). The blood test measures levels of a protein called CA125, which is often elevated in the blood of women who have ovarian cancer. The research team used statistics to determine the risk of ovarian cancer based on the woman’s age, how much CA125 was present in their blood and how the level changed with time. The ultrasound scan is used to look for abnormalities in the ovaries. Ovarian cancer, often referred to as ‘the silent killer’, causes more deaths than any other cancer of the female reproductive system. When it is detected early – that is, when the disease is still confined to the ovary – it is 90% curable. However, because there are few or no early symptoms, 70% of women with ovarian cancer are diagnosed with advanced-stage disease, when the survival rate is only 20–30%. Currently, there is no effective screening test to detect early stage disease. However, recent advances in transvaginal ultrasound and the development of a risk score for the interpretation of the results of the blood test for the tumour marker CA125, suggest that screening for ovarian cancer could now be possible. In the course of the UKCTOCS study, between 2001 and 2005, 202,638 post-menopausal women aged between 50 and 74 were recruited through 27 regional Primary Care Trusts across the UK. Women were randomly assigned to no treatment (control), annual multimodal screening (MMS), or annual screening with transvaginal ultrasound (UUS) in a 2:1:1 ratio. Women with repeat abnormal screens underwent clinical evaluation and surgery. Findings showed that the screening programmes using MMS and USS ISSUE 3 APRIL 2009 7 SLMS RESEARCH Research focus were able to detect symptoms in 90% and 75% respectively of those women who developed ovarian cancer. The authors of the report believe that the fact that almost half of the cancers detected were in stages I or II (48% of these in stage I) is encouraging, since currently only about 28% of invasive cancers are detected at this early stage in most ovarian cancer series. Overall, the total number of cancer cases detected (87 primary ovarian and three fallopian tube cancers) in the screening groups was similar: 42 in the MMS group and 45 in the USS group. The authors note that the correct identification of true negatives was significantly better in the MMS than in the USS group, resulting in fewer repeat tests and almost nine times fewer operations per cancer detected. They add, however, that the overall results show that both screening strategies have good performance characteristics and are feasible on a large scale. Dr Usha Menon, the UKCTOCS trial co-ordinator and one of the principal investigators, said: “These results are extremely encouraging. […] The early results suggest that both types of screening can be used on a large scale and both successfully identify ovarian cancers.” and healthcare workers in the UK collaborate in research and involve volunteers nationwide to improve health.’’ The UKCTOCS trial has been funded by the Medical Research Council (MRC), Cancer Research UK and the National Institute for Health Research and is supported by the gynaecological cancer research charity The Eve Appeal. Economic recessions and the individual live course Staff in the Division of Population Health have undertaken research into how previous economic recessions affected the health and well-being of individuals. This research becomes increasingly important as the UK faces the present downturn. Past research focused on unemployment alone, and its possible influence on the risk of suicide and heart disease mortality, as well as on mental health. During the recessions of the 1980s and 1990s there was little consideration that individuals likely to suffer most at times of economic downturn were those who had already faced adversities in their earlier lives. Professor Ian Jacobs concluded: “I believe the UKCTOCS trial is an example of UK healthcare at its best. It is a combination of a huge research effort, involving charity, research council and Government funders, hospital staff, university researchers and GPs around the UK and crucially more than 200,000 women. The first 8 results are an important step forward and the trial itself is a powerful demonstration of how our best scientists, clinical researchers UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Nor did we investigate the possibility that a spell of unemployment might knock people off a favourable life trajectory. The ESRC International Centre for Life Course Studies in Society and Health (ICLS) is well placed to relate research on health and well being in past recessions to what service providers might expect in the present one. Previous work by Centre members has shown that those who become trapped in unemployment for longer periods tended to come from less privileged homes with lower paid parents and greater overcrowding. They tended also to have had more behavioural problems and less academic success during their school years. However, large amounts of unemployment could have a detrimental effect over long periods of time even on individuals from more privileged homes, with good educational qualifications and high intelligence. The graph shows that people with high IQ who had suffered over 36 months of unemployment in the 1980s recession were hardly any more likely to engage in healthy behaviours such as not smoking, healthy diet and taking exercise than others with lower IQ who had a stable work history with no unemployment. Proportion with healthiest behaviours at age 33 by IQ at age 11 and amount of unemployment 30 None 25 1-12 months 13-36 months 20 37+ 15 10 5 0 Top IQ Bottom IQ ISSUE 3 APRIL 2009 SLMS RESEARCH Research news Professor Brian Henderson (UCL Eastman Dental Institute) awarded £240,000 grant funding from the British Heart Foundation Del Besra), QUB (Professor Karl Hale), Oxford (Professor Edith Sim), St Georges (Professor Coates and Professor Butcher), Birkbeck (Dr Sanjib Bhakta), School of Pharmacy (Professor Peter Taylor) to form the UK tuberculosis drug development consortium (TBDUK). Professor Brian Henderson (UCL Eastman Dental Institute) has received £240,000 (Fec equivalent £432,000) from the British Heart Foundation for a study entitled: Circulating Cell Stress Proteins, Lymphocyte Function, and Cardiovascular Disease. This application is with Professor Andrew Steptoe, UCL Research Department of Epidemiology and Public Health and Dr Steve Thompson, Department of Immunology, King’s College London and is to study the relationship between circulating levels of the cell stress protein, heat shock protein (Hsp)60, and leukocyte function in participants in the Whitehall Study - a prospective study of cardiovascular risk factors. This is part of ongoing studies at UCL EDI to identify the pathological roles of bacterial and human cell stress proteins. This group have been awarded a “Collaboration” grant from the Medical Research Council. The new award which will be administered by UCL will provide a synergistic environment for academic and commercial organisations researching new drugs. It is hoped that the consortium will bring together others engaged in drug development activity together, increase the funding available to TB drug discovery and develop a system that will support the identification of new candidates, early testing and drug improvement through chemical modification and all stages of clinical drug development. Even in its early days the consortium has been awarded a new research grant to develop drugs that attack the tuberculosis bacterial cell wall. If successful, the TBDUK will reverse the decline in UK antibiotic development research and create the new drugs to defeat this worldwide scourge. For more information contact: Professor Brian Henderson, tel: 020 7915 1190 TB Drug Development UK – a new grant from the Medical Research Council UCL researchers (Professor Gillespie and Dr Tim McHugh) have joined with academics from seven centres around the UK who are active in tuberculosis research: Strathclyde (Dr Geoff Coxon), Birmingham (Professor £95,000 donation to UCL cancer research Bottoms Up, a North-West London bowel cancer charity, has donated £95,000 to UCL to buy a vital piece of equipment to aid cancer research. The ‘CellSearch’ machine, which helps to detect tumour cells in the blood stream, was presented at an event at the UCL Cancer Institute in March. UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Professor Chris Boshoff, Director of the UCL Cancer Institute, said: “The generous funding raised by Bottoms Up, combined with funding from the National Institute for Health Research, has allowed us to purchase this equipment and fund a technician and running costs. We believe that this initiative will play an important role in the monitoring of patients being treated for cancer and that this technology will play an expanding role in cancer research within UCL.” Dr Tim Meyer, Senior Lecturer in Oncology (UCL Cancer Institute), said: “The CellSearch machine has been designed to detect individual circulating tumour cells which have become detached from the main tumour and released into the blood stream. The machine is very sensitive and able to detect even one or two cells present in one tube of blood. Recent research has shown that the number of circulating cells detected can provide important information about the prognosis in individual patients, and can also be used to detect relapse or disease progression.” Tina Hancock, Chairman of the Bottoms Up bowel cancer charity, says: “As a small, local charity we have in the past donated funds to the Royal Free Hampstead NHS Trust for vital early diagnostic equipment for bowel cancer. When Anthony Glantz, the husband of one of our committee members, sadly died of the disease two years ago, we decided to look at research opportunities to support. As soon as we heard about the need for the CellSearch machine for the UCL Cancer Institute we knew that we had found the perfect fund-raising goal. It has been ISSUE 3 APRIL 2009 9 SLMS RESEARCH an absolute privilege to be associated with UCL and the fantastic research work carried out at the Institute.” Bowel cancer, also known as colon or colorectal cancer, is the second most common cancer to kill people in the UK, causing more deaths every year than breast and cervical cancer combined. Around 35,000 people in the UK will be diagnosed with bowel cancer in 2009. HTA award for collaborative research project into recall intervals for dental check-ups Professor Ian Needlman (UCL Eastman Dental Institute) is Co-applicant on a NIHR Health Technology Assessment programme funded grant totalling £596,000 for research into recall intervals for dental check-ups. The Chief Investigator is Professor Nigel Pitts at the Dental Health Services Research Unit (DHSRU), Dundee University. The study, named the INTERVAL Dental Recalls Trial (Investigation of NICE Technologies for Enabling Risk-Variable-Adjusted-Length Dental Recalls Trial), is an initial 18 month study into the effectiveness of different recall intervals for dental check-ups and, if successful, will be extended to a four-year trial. It will compare three groups: check-ups at variable intervals determined according to individual risk, as recommended by the current NICE guidance; six monthly check-ups; and recalls at 24 months. The research will 10 look at the psychological impact of the different check-up intervals as well as the incidence of caries and periodontal disease. The study has been designed to address and answer research questions resulting from the NICE Dental Recall Guideline (2004) for which Professor Needleman carried out the periodontal health research synthesis. The resulting trial is an excellent example of clinical research responding to priorities identified in systematic reviews. For further information contact: Professor Ian Needleman, tel: 020 7915 1075 UCL Ear Institute magnetoencephalography (MEG) device In March the UCL Ear Institute took delivery of one of the world’s first magneto-encephalography (MEG) devices specifically designed for experimental work in small animals. A collaborative research programme between UCL, Kanazawa Institute of Technology (KIT), Japan and the Centre National de la Recherché Scientifique (CNRS), France, the MEG device will open up a whole new arena of research possibilities, enabling researchers to bridge the gap between traditional single-neuron recording techniques employed in auditory research and human brain-imaging technologies. MEG employs so-called superconductive quantum interference devices (SQUIDS) to record tiny magnetic signals generated, in this instance, by neurons in the brain’s auditory cortices. MEG is proving a powerful new tool in the repertoire of human brain-imaging, and is particularly suited to studies of the auditory system, where timing of sounds is crucial. The teams from KIT and CNRS joined the Ear Institute team UCL SCHOOL OF LIFE AND MEDICAL SCIENCES for 4 days of installation and trials, and included a visit to the London Centre for Nanotechnology where pioneering research is underway developing the next generation of SQUID sensors. Good practice agreement involving d/Deaf children in academic research A good practice agreement has been coordinated by The Deafness Cognition and Language Research Centre (DCAL) at UCL and The Sign Bilingual Consortium on involving d/ Deaf children in academic research. The agreement came about following consultation which highlighted that both schools and University researchers were keen to formalise and improve their relationship and shared a desire to ensure good practice when carrying out research into d/Deaf children’s development. The agreement was originally drawn up between coordinating partners based in London at DCAL and Frank Barnes School for Deaf Children but the principles in this document are applicable to all educational settings for d/Deaf children. A wide range of organisations contributed to the agreement including City University and, Oxford Brooks University as well as the universities of Sheffield, Leeds, Bristol, Plymouth and Newcastle. Other organisations outside the higher education sector signing up include The British Association of Teachers of the Deaf (BATOD) and The National Deaf Children’s Society (NDCS). A copy of the agreement can be downloaded from: www.batod. org.uk/content/articles/research/ gpa081008.pdf. ISSUE 3 APRIL 2009 SLMS RESEARCH Publication of British Sign Language (BSL) norms for age of acquisition, familiarity, and iconicity One of the reasons research into BSL has wide reaching impact is because it offers the opportunity to think about important questions about language that it may not be possible to address by just looking at spoken languages alone. Up till now this research has been hampered by the fact that there was not sufficient research on the age of acquisition, familiarity and iconicity of individual signs. In contrast there is a wealth of data on spoken or written language such as the massive British National Corpus sample of 100 million words. Researchers at the Deafness Cognition and Language Research Centre (DCAL) at UCL have now published normative data on 300 lexical signs. This will be available to other academic researchers as well as feeding into an assessment tool that will be useful for teachers, interpreters, social workers and language therapists. Data was collected from a wide range of BSL signers all over the UK using an on-line questionnaire that could support BSL streamed video (www.RiddleMeThis.net). This enabled anybody with access to high-speed internet access to take part in the research. Further details about the research can be found at http://brm.psychonomic-journals. org/content/40/4/1079.abstract. The norms may be downloaded from the following website: www.psychonomic. org/archive. Research HIGHLIGHTS Key resource will help address complications in pregnancy A new resource at the UCL Institute of Child Health (UCL ICH) will help doctors and scientists address the four key complications in pregnancy. Jointly led by Professor Gudrun Moore (UCL ICH) and Professor Lesley Regan (St Mary’s Hospital, Imperial College London), the resource – known as the Baby Bio Bank – will be the first study of its kind and the most extensive, as it will analyse maternal and paternal inheritance patterns. The four key complications during pregnancy are recurrent miscarriage, intrauterine growth restriction (abnormally small babies), pre-eclampsia (highblood pressure in pregnancy) and preterm delivery. 250,000 UK pregnancies end in miscarriage per annum, while over 50% of stillbirths remain unexplained. The resource will help doctors identify the inherited and biological nature of these complications. The resource will also store protein from the placenta for expression and translational studies (the process by which inheritable information from a gene is made into a functional gene product). The research at the bank will involve collecting blood samples from the parents and placenta from the babies affected by any of these complications. The samples taken will be examined to investigate the possible underlying causes of these conditions and how much inheritance plays a part. Parents in London can help address these serious conditions by anonymously donating blood and placenta samples. The bank will be based at UCL ICH and St Mary’s Hospital, Imperial College London. It will create a panLondon project and an international resource, bringing together eminent professionals in the fields of obstetrics and gynaecology. Once complete, the research database will be available to researchers from all over the world to share. Professor Moore said: “It is a huge and exciting collaboration between UCL and Imperial College London, and between medicine and science. It will enable breakthroughs in the diagnosis and treatment of these four serious pregnancy complications.” ISSUE 3 APRIL 2009 11 SLMS RESEARCH UCL scientists show how brain records memory Professor Eleanor Maguire (UCL Institute of Neurology) and Demis Hassabis have published research which confirms that it may be possible to ‘read’ a person’s memories just by looking at brain activity. In a study published in the journal Current Biology, the researchers show that our memories are recorded in regular patterns, a finding which challenges current scientific thinking. Professor Maguire and Demis Hassabis have previously studied the role of a small area of the brain known as the hippocampus which is crucial for navigation, memory recall and imagining future events. Now, the researchers have shown how the hippocampus records memory. When we move around, nerve cells (neurons) known as ‘place cells’, which are located in the hippocampus, activate to tell us where we are. 12 Professor Maguire and colleagues used an fMRI scanner, which measures changes in blood flow within the brain, to examine the activity of these places cells as a volunteer navigated around a virtual reality environment. The data were then analysed by a computer algorithm developed by Demis Hassabis. “We asked whether we could see any interesting patterns in the neural activity that could tell us what the participants were thinking, or in this case where they were,” explains Professor Maguire. “Surprisingly, just by looking at the brain data we could predict exactly where they were in the virtual reality environment. In other words, we could ‘read’ their spatial memories.” brains. By looking at activity over tens of thousands of neurons, we can see that there must be a functional structure – a pattern – to how these memories are encoded. Otherwise, our experiment simply would not have been possible to do.” Professor Maguire believes that this research opens up a range of possibilities of seeing how actual memories are encoded across the neurons, looking beyond spatial memories to more enriched memories of the past or visualisations of the future. Earlier studies in rats have shown that spatial memories – how we remember where we are – are recorded in the hippocampus. However, these animal studies, which measured activity at the level of individual or dozens of neurons at most, implied that there was no structure to the way that these memories are recorded. The work by Professor Maguire and Demis Hassabis appears to overturn this school of thought. “Understanding how we as humans record our memories is critical to helping us learn how information is processed in the hippocampus and how our memories are eroded by diseases such as Alzheimer’s,” added Demis Hassabis. Professor Maguire said: “fMRI scanners enable us to see the bigger picture of what is happening in people’s Professor Maguire led a study a number of years ago which examined the brains of London taxi drivers, who UCL SCHOOL OF LIFE AND MEDICAL SCIENCES “It’s also a small step towards the idea of mind reading, because just by looking at neural activity, we are able to say what someone is thinking.” ISSUE 3 APRIL 2009 SLMS RESEARCH spend years learning “The Knowledge” (the maze of London streets). She showed that in these cabbies, an area to the rear of the hippocampus was enlarged, suggesting that this was the area involved in learning location and direction. The new study confirms that the patterns relating to spatial memory were located in this same area, suggesting that the rear of the hippocampus plays a key role in representing the layout of spatial environments. National Medical Laser Centre The National Medical Laser Centre is one of the most comprehensive medical laser research centres in Europe. The major emphasis is on translational research - understanding the interaction of light with living tissue in the laboratory and using the results to develop new techniques for the diagnosis and treatment of human disease. It is a world leader in photodynamic therapy (PDT -the combination of light and a photosensitising drug), having defined much of the biology that has led to clinical applications in the treatment of dysplasia and cancer in the mouth, oesophagus, lungs and other organs. It was the first centre to describe image guided, minimally invasive PDT for cancers of the prostate and pancreas and as an adjuvant to balloon angioplasty to prevent re-stenosis. With each new laser technique, the aim is to find out how best to use it in any particular clinical situation and then to undertake trials to compare it with the best available conventional alternatives, recent work includes: • Using light to detect cancer in the lymph nodes of breast cancer sufferers, which recently won a prestigious Medical Futures Innovation Award. • Measuring drug concentrations in patients using white light measurements, optically scan excised oesophageal nodules, and provides clinical support for Photodynamic Therapy treatments including studies in the prostate, oesophagus and bile duct. • Targeted nano-systems for photodynamic therapy and diagnosis of cancer: In this project UCL SCHOOL OF LIFE AND MEDICAL SCIENCES the use of nanoparticle delivery systems are being investigated in order to achieve a more efficient and selective delivery of a clinicallyapproved photosensitiser to tumour cells, both for therapy and diagnostic imaging. A range of targeted and non-targeted nanocarriers (liposomes, polymeric and silica nanoparticles) are supplied by project partners and their pharmacokinetics assessed in comparison to the effect of PDT treatment. • Diagnosis and management of pre-cancerous lesions (dysplasia) in Barrett’s oesophagus. This includes evaluation of biomarkers (aneuploidy/ tetraploidy) that may help to identify patients who are more likely to develop dysplasia and can also predict success of treatment. • Elastic Scattering Spectroscopy Optical Biopsy system to detect cancer and HALO Radiofrequency Ablation to treat the lesion. Further information about the Centre is available at: www.ucl.ac.uk/surgery/nmlc/ ISSUE 3 APRIL 2009 13 SLMS EDUCATION New Graduate Opportunities from September 2009 The teaching will include lectures, tutorials and field work and the modules have been formatted to allow one day per week attendance. This course is open to both medical graduates and non medical graduates with an appropriate physiotherapy background. This particularly includes those in orthopaedics, rheumatology, sports medicine, General Practice and geriatrics; and nurses, osteopaths, physiotherapists, and Allied Health Professionals such as biologists, bioengineers and pharmaceutical or medial devices industry trainees. Students may undertake the programme on a full-time (one year) or part-time (two years) basis. Further information is available on the Division website: www.ucl.ac.uk/surgicalscience/ MSc in Frontiers in Infection & Immunity MSc in Sports & Exercise Medicine The Division of Surgery & Interventional Science will launch a new Masters’ programme entitled ‘Sports and Exercise Medicine in September 2009. The programme is designed to give a broad understanding of sports medicine, sports injuries and exercise and health. The fundamental basis for musculo-skeletal injuries, the diagnosis and management of common sports related problems and research into musculo14 skeletal injuries will all be covered. There are optional modules such as sports dentistry and sport in extreme environments. The Division of Infection & Immunity will launch a new Masters’ programme entitled ‘Frontiers in Infection and Immunity’ in September 2009. The programme is unique and aims to train young scientists or clinicians in the field of infection and immunity. It offers a varied diet of courses and a specialist research project that leads to a specialism in clinical microbiology, tropical microbiology, virology or immunology. Exciting new themes have been introduced that reflect the research and clinical excellence within UCL’s Division of Infection and Immunity. These include courses on: Biofilms in health and disease (including quorum sensing and device-associated infections); HIV research frontiers to clinic (covering lentiviral vectors for use in gene therapy) and Frontiers in therapeutics: from lab to clinic (describing drug discovery through to UCL SCHOOL OF LIFE AND MEDICAL SCIENCES clinical trials). The programme is also open to students wishing to obtain a postgraduate diploma or postgraduate certificate. Students may undertake the programme on a full-time (one year) or flexible (from two to five years) basis to suit their individual needs. Further information is available on the Division website: http://www.ucl.ac.uk/ medicalschool/infection-immunity/ MSc in Reproductive Science & Women’s Health In September 2009 the Institute for Women’s Health will launch a new Masters’ programme entitled ‘Reproductive Science & Women’s Health’. The programme will provide medical, science and nursing students with a comprehensive knowledge and understanding of the field of reproductive science and women’s health, specifically human genetics, female physiology and anatomy, reproductive health, gametogenesis, preimplantation development and IVF, pregnancy and childbirth, prenatal diagnosis and screening, preimplantation genetic diagnosis, breast and reproductive cancers. The MSc programme structure consists of an eight month lecture and practical programme and a four month research project. Each module is run over a three week period and examined by workbooks, essays and exams. Three modules are taken in term 1 and 2, and two modules in term 3. The project runs from June to September. Throughout the course all students have observation days in the IVF and Fetal Medicine unit. ISSUE 3 APRIL 2009 SLMS EDUCATION EDUCATION NEWS New e-Learning initiative for final year students on the MB BS programme In 2008 UCL Medical School’s Year 5 Curriculum Manager, Pratibha Kothari, in conjunction with Dr Anita Berlin and Dr Aroon Lal, piloted the use of e-Learning revision resources for final year students using the centrally supported virtual learning environment, moodle, and audio recordings of lectures. In recent months Ms Kothari, aided by Jason Norton, developed this e-Learning resource, using ITunes, MP3, and audio lectures. In addition, online assessments, based on the format of the finals; and an online forum have been developed by former students, Dr Paul McGovern and Dr Zaheer Mangera, in conjunction with Ms Kothari. Dr McGovern and Dr Mangera use the forum to post answers to student questions about the MB BS finals and Ms Kothari answers questions about administration of the degree programme. Ms Kothari said, ‘The extensive and growing use of online resources and materials in learning and teaching presents new opportunities, we feel it is important to use the technology available in order to develop this resource for final year students. We will solicit feedback from students and based on their comments and suggestions we will continue to develop the material available. Next year we would like to use ‘ProfCast’, a versatile tool for recording presentations including PowerPoint and Keynote slides, to create enhanced podcasts’. Professor Peter Mobbs, Executive Dean UCL Faculty of Life Sciences, said, ‘Staff have worked hard in order to make this e-Learning resource a success, it required a clear strategy, careful planning, solid instructional design, and commitment on the part of those involved; I have no doubt that we will continue to build on this success.’ UCL SCHOOL OF LIFE AND MEDICAL SCIENCES UCL Health and Society Summer School (13 – 17 July 2009) Social Determinants of Health The summer school is designed for two types of participant: those who already work in the field of public health and who want to refresh their knowledge of population health, and those who are considering a career in public health or related research such as social epidemiology. Our course is multi-disciplinary. Topics covered include: Class, Work, Gender, Ethnicity, Socialbiological translation, Lifecourse epidemiology, Disability, inequality and human rights, Russian mortality crisis, Public health ethics, Politics of health and equity, Globalization and health and Inequalities in dental public health. Michael Marmot will open the summer school with a presentation on the social determinants of health and close the week with a lecture and discussion on national and international policy development. Members of the Strategic Review of Health Inequalities in England (Marmot Review) have been invited to brief summer school participants. Richard Wilkinson will give a guest ISSUE 3 APRIL 2009 15 SLMS EDUCATION lecture on relative deprivation and income inequality. Summer school participants will also be invited to a public lecture on the financial crisis and health by Professors Blane & Bartley and Dr Eric Brunner. The summer school will be held at UCL which is located in central London, close to Regent’s Park, the British Museum, the British Library and West End shops and theatres. History of Medicine at UCL presents a series of podcasts on the history of neuroscience featuring eminent people in the field, Today’s Neuroscience, Tomorrow’s History, has been a huge success. Further information about this series is available at: www.ucl.ac.uk/ histmed/audio. MBBS and Postgraduate Review – update from DoME The full programme will run Monday – Friday between the hours of 9 – 5pm approximately with additional evening lectures on Tuesday and Thursday. Further information is available at: www.ucl.ac.uk/healthandsociety Dick Whittington Medical Summer School (6 -10 July 2009) Each summer UCL runs the Dick Whittington medical summer school for thirty Year 11 students from Camden and Islington. The week of activities gives pupils the opportunity to meet and work with medical staff and patients and to visit different hospital departments and GP practices. The summer school gives them a taste of hospital life and working in the medical professions. Dates of the school are 6 -10 July 2009. The closing date for applications is 8 April 2009, further information is available at: http://www.pcps.ucl.ac.uk/ dickwhittington 16 Today’s Neuroscience, Tomorrow’s History podcast series Supported by a grant from the Wellcome Trust to Dr Tilli Tansey and Professor Leslie Iversen, the Wellcome Trust Centre for the The education reviews of the MBBS course and of postgraduate taught courses in FBS, are now starting to produce some significant changes. The reviews, carried out last academic year, had a catalytic effect and generated a lot of very productive discussion about ways of improving teaching and learning throughout the faculty. This means that, as well as the broad recommendations of the original reviews, DoME have also had more specific recommendations from working groups and teaching committees which they have agreed to implement. The education reviews and the subsequent discussion has clearly demonstrated the enormous amount of skill and enthusiasm for teaching and learning, from those involved at every level. DoME’s task now is to deliver on the agreed recommendations from the original reviews, while recognising that the creativity of our staff and students will continue to generate new ideas and initiatives. UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Examples of current developments include: Within the MBBS course: • DoME have implemented all of the recommendations for welfare and careers from the MBBS review. The Welfare system is now integrated across the MBBS with improved support and training for staff involved. Careers advice and support has been enormously enhanced, including the creation of a dedicated web page with student factsheets and timetabled sessions on careers throughout the course. • DoME are improving the integration of the MBBS course, which is now managed entirely through FBS. Assessment is being harmonised throughout the course, including the introduction of SBA (Single Best Answer) items and Anghoff-based standard setting in each phase. Modules in different phases with common themes (e.g. Circulation and Breathing in Phase 1 and Respiratory Medicine in Phase 2) have been working collaboratively to ensure that students are made aware of how the course material builds on, and links to, their previous learning. Module Management Groups are in place for vertical modules such as Drugs and Use of Medicines to co-ordinate teaching throughout the course. • DoME are redesigning the Medical School’s web pages, in keeping with the overall template for the School of Life and Medical Sciences, to improve the accessibility of information for students, staff and our external audience. • DoME have reviewed our final year curriculum and will be introducing longer clinical attachments as part of this. Students will spend a 16 week block at the same District General ISSUE 3 APRIL 2009 SLMS EDUCATION Hospital, giving staff there a much greater opportunity to get to know them, assess their learning needs and objectives and support them both academically and pastorally. These changes will feed through to the other phases in due course, to ensure that each stage of the course has explicit linkages to the overall outcomes students are expected to achieve. • DoME have reconstituted the MBBS Resources and Facilities Committee, under the chairmanship of Dr Jean McEwan. This will now be the first point of contact for these issues for the MBBS course and Dr McEwan will refer them onward as appropriate. Mobile Data Collection Unit Staff in UCL Research Department of Computer Science have commissioned a purpose-built Mobile Unit that can be moved by virtually any driver using a 4x4 vehicle. The unit will contain when fully equipped two 3D body scanners, height gauge, 3D foot scanner, plus a Body Composition Monitor. A single 3D body scan provides: 200 linear measurements (e.g. waist, hips etc. and ratios), 3D body shape (e.g. posture), and skin surface area (e.g. whole body, body part). The Body Composition Monitor provides body composition and weight. In addition, the Computer Science Department has developed a comprehensive software infrastructure to manage data collection. It comprises: a registration and briefing website, survey management software (e.g. tracking subjects), software for integrating the data collection equipment, software for uploading data, and we are working on specialist data analysis tools. Within postgraduate education: • DoME have drawn up Faculty guidelines for the modularisation of taught masters’ courses including guidelines for module size and credits. DoME have modularised all taught masters courses within the Faculty and each Division is currently harmonising local time-tables in order to offer a suite of masters courses with options to pick-and-mix modules between courses. • DoME have an approved policy on improving PhD submission rates. • DoME have entered discussions with professional market researchers to develop our marketing and branding. Configuring of the mobile unit has been a pan-UCL effort with equipment donated by the Child Growth Foundation to ICH being loaned by Dr Jonathan Wells, and other equipment being purchased by UCL Computer Science. The website and survey management software was developed as a group project by a team of Computer Science students and another team is installing the equipment and writing the necessary software to link the equipment, download collected data into an onboard server, and also software to upload subjects’ data to a central server. Once the Unit’s equipment and software is configured students on the UCL MSc in Clinical & Public Health Nutrition will conduct projects in nutrition and sport’s exercise using cohorts of students. This will be used to ‘debug’ and commission the mobile unit. It is hoped that charities such as the Child Growth Foundation and BHF utilise the unit as a centre-piece for campaigns for a healthy lifestyle; that sports organisations use it to develop UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Good progress has been made on implementing the recommendations from the reviews and many more ideas have been produced from the discussions which the reviews have generated. Looking ahead, the next major development, which is crucial to the next phase of implementation, is the creation of a SLMS Education Deanery. This will allow DoME to make more progress on integrating the provision of education in both Faculties at both undergraduate and postgraduate levels. For example, through the SLMS e-Learning Advisory Group, DoME are working towards providing support and guidance for individuals setting up e-learning programmes, and linking people together on e-learning matters in undergraduate and postgraduate education. software to match young people to sports where they might excel based on their body shape, and thus promote exercise; that healthcare researchers in nutrition and epidemiology use it to survey body measurements and the impact that better nutrition, health care and the influence of sedentary lifestyles has on the widening of the human form. UCL Computer Science has over 300 students who provide a pool of talent for developing software for analysing body shape and skin surface area etc. They are keen to do ‘real projects’, and would welcome the opportunity to collaborate with other departments and outside organisations. Over the next few weeks they will invite potential stakeholders to visit the unit to discuss possible collaborations and also to enable use to get their input on the design and aesthetics of the unit. For further information contact Professor Philip Treleaven, tel: 020 7679 7288, Email: p.treleaven@ucl.ac.uk ISSUE 3 APRIL 2009 17 SLMS NEWS SLMS news round up New tissue culture equipment in the Cruciform laboratories Following substantial investment by the Faculty of Life Sciences and the UCL Teaching Equipment Executive sub-Committee over the last three years the Cruciform Teaching Facility (CTF) is now equipped to employ mammalian cell culture as part of practical teaching. Facilities include: •E ight excellent laminar flow hoods for sterile cell culture work. Each hood is equipped to allow up to two students to work side-byside and each has two vacuum aspirators and flasks (for the safe removal of liquids) and two pipettors for media handling. Six of the eight hoods are on trolleys and can be moved between the two wet laboratories to allow different teaching configurations. •T he laboratories share three large CO2 cell culture incubators for the maintenance of cultures. •T here are sixteen inverted microscopes each with high and low power magnification for the examination of cells. There are also a very large number of conventional microscopes and haemocytometers for cell counting. •F our members of the CTF staff now have experience of preparing sterile cell cultures for large classes (so far up to 96 students requiring more than 200 flasks) and can prepare, 18 aliquot and distribute sterile buffers, enzyme solutions and media for each student along with autoclaved glassware and disposable pipette tips. Staff can also manage the safe disposal of all by-products. generated income from a charity ball and a sponsored bike ride (from London to Paris). ‘I do not know of any other university teaching facility that is so well equipped for this aspect of modern cell biology’, said Professor Elizabeth Shephard, Department of Structural and Molecular Biology, ‘Professor Chris Danpure and I now have substantial experience in the design and supervision of classes using cell culture that are suitable for undergraduates or postgraduates. We would be happy to help colleagues learn how to include this type of work in their courses.’ Professor David Isenberg, UCL Centre for Rheumatology, said: “We’re delighted to welcome Anna here today to open these new facilities. We have two main research groups – adolescent, directed by my colleague Professor Pat Woo, and adult – and the refurbishments mean that these groups can now work together more closely. The general environment is also now much more pleasant. We will continue carrying out research here to help further our understanding of this group of diseases and help improve the treatment we offer our patients.” New facilities at the UCL Centre for Rheumatology New offices and research laboratories were opened by the well known British actress Anna Chancellor. The facilities are part of the UCL Centre for Rheumatology, based in the Windeyer building on Cleveland Street in Camden. Work carried out at the Centre helps to further the understanding and treatment of debilitating autoimmune rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus. The labs and offices used by the Centre’s staff have been reorganised, extended and redecorated. The refit cost in the region of £150,000, with money contributed by UCL and through fundraising carried out for the unit by organisations including the Arthritis Research Campaign (ARC) and The Rose Foundation and strongly supported by patient- UCL SCHOOL OF LIFE AND MEDICAL SCIENCES The UCL Centre for Rheumatology is one of the leading academic rheumatology units in the UK. As well as seeing over 3,000 new patients and over 15,000 follow-ups annually, the Centre undertakes an enormous amount of clinical and basic research aimed at increasing understanding of the causes of musculoskeletal diseases such as rheumatoid arthritis, lupus, Sjogren’s syndrome, the antiphospholipid antibody syndrome and vasculitis, as well as finding ways to optimise the management of patients with these conditions. The clinical work of the Centre is based in University College London Hospital, part of University College Hospital NHS Foundation Trust. ISSUE 3 APRIL 2009 SLMS NEWS CO-EXISTENCE A new work by German-born product designer Julia Lohmann will provide bold viewing for passers-by on London’s Euston Road. ‘Co-existence’ is the latest commission for the Wellcome Trust’s window display and consists of 9000 petri dishes brightly illuminated with colours and designs that form the shape of two naked women lying head-to-head. Inspired by the unseen universe consisting of at least 2000 different species of microbe that inhabit our bodies (microorganisms including bacteria, viruses and fungi), Julia Lohmann has produced pixellated photographic images of the colonies of the most common species, which appear on the bases of the petri dishes. The positioning of each microbe within the artwork shows the part of the human body in which it most commonly lives. Selected dishes have been drawn on, adding visual interpretations of imagined microbes and helping to form the outline of the human body. Julia Lohmann explains: “It’s been really fascinating delving into the science behind our bodies. When I started work on the project, I did not realise that we are hosts to such a vast number of different species of microbe. We decided to use the female form as females contain a greater variety of microbes than males, which is a surprise in itself!” Julia Lohmann consulted Professor Michael Wilson, a microbiologist at the University College London (UCL) Eastman Dental Institute, whose recent book ‘Bacteriology of Humans: An ecological perspective’ describes the bacterial communities that live on the body. Information from this book was used to identify those bacterial species that inhabit particular regions of the body. Dr Derren Ready, a Clinical Scientist in Professor Wilson’s laboratory, grew and photographed colonies of the various bacteria used in the display - a total of 750 images were produced. Professor Wilson comments: “Only one in ten of the cells comprising a human being is mammalian - the rest are microbes and multicellular organisms. This symbiotic association between mammalian cells and microbes forms the stable, living structure which we think of as the human body. So, in reality, the human body is not only a beautifully integrated assembly of organ systems, it is also a complex ecosystem that provides a variety of environments - each of which is populated by a distinct microbial community. A symbiotic existence is probably the most common form of life on this planet and we humans are popular hosts. I’m delighted that Julia has used this concept as an inspiration for her work.” SLMS Student news Changes to RUMS RUMS held two very successful General Meetings which allowed all those present to really influence the RUMS Executive Officers. Aside from various campaigns and policies on issues, there are two major changes: the new constitution and the new name. After a long discussion in the first General Meeting, the students of RUMS made a bold decision to change the name of the society to reflect the historic nature of the institution and the influence that the past has had on its current form. RUMS will now stand for Royal Free, University College, and Middlesex Medical Students’ Society. Incorporating the word ‘Middlesex’ into the title was one that has been welcomed by the Medical School and one that will hopefully remind the students of future years that they belong to an institution with a rich and long history. The second significant change is to the make-up of the RUMS Executive Team; it will now operate with new Media, Events, Campaigns, and Welfare Officers to complement Education Officers and the Sports and Societies Officer. RUMS Executive Team is confident that this new system will help to better represent the medical students as well as provide a much more consistent provision for extracurricular activities. The new constitution will come into affect from the next academic year, pending approval from Union Council. Please forward comments or questions, to Billy Street, Medical and Postgraduate Students’ Officer, UCL Union, email: mps.officer@ucl.ac.uk. UCL SCHOOL OF LIFE AND MEDICAL SCIENCES ISSUE 3 APRIL 2009 19 SLMS PEOPLE INTERVIEW David Shanks Professor of Psychology and Head of the Division of Psychology and Language Sciences Tell us about the Division of Division of Psychology and Language Sciences? We are one of two Divisions within the Faculty of Life Sciences. Our Division came in to existence last year in a reorgansation of Life Sciences and comprises of the staff who used to be in three Departments: Psychology, Human Communication Science, and Phonetics and Linguistics. Our Division comprises of approximately 110 academic staff, divided in to a series of research units, they cover Cognitive Neuroscience, where UCL is extremely strong; Basic Experimental Cognitive Psychology, on topics like vision, perception, learning, memory and language; Linguistics; Clinical and Educational Psychology, that group is very heavily involved in professional training for Clinical Psychologists and Educational Psychologists; Developmental Science, we have quite a strong history at UCL with research in to, Child Development and Developmental Disorders; we have a smaller group that we share with Computer Science, which does research and teaching on human computer interaction – the design of technology with a psychological design angle to it; Language & Communication, where there is much research on speech 20 disorders and therapy; and Speech Hearing and Phonetic Sciences, which is a research group that is very strong on phonetics, speech perception, and hearing technology like hearing aid development. A happy coincidence of the merging of the Departments in to the Division was the co-location of many of the staff, who work in the field of language sciences, into the fabulously refurbished building, Chandler House. Human Communication had many of their staff in the building previously but these language science groups are now co-located there. We have three undergraduate teaching programmes in Psychology, Linguistics, and Speech Sciences. The quality of our undergraduate students is exceptional, these programmes are all successful and are a major part of our activity. We have a considerable number of research-led masters’ programmes, both MA’s and MSc’s, and this is an area that we are keen to continue to expand. We offer programmes in a wide range of topics from Psychoanalysis to Cognitive Neuroscience, language related topics and decision making. The majority of these programmes are extremely successful and attract a large number of overseas students. We have a lot of students doing conventional PhD/research doctorates but the third major strand of our teaching is in professional training – which means taught doctorates. In Clinical Psychology, we are the largest trainer in the UK and we are probably one of the largest trainers in the world UCL SCHOOL OF LIFE AND MEDICAL SCIENCES in training Clinical Psychologists for careers in the health service. Many of the students who graduate from our undergraduate psychology degree aspire to get in to Clinical Psychology, but it is an extremely difficult and competitive field. We also have a much smaller but equally prestigious programme for Educational Psychologists who would then typically work for Education Authorities. For us, undergraduate and graduate training is big business. We are one of the largest Divisions within UCL in terms of teaching load, we have around 1000 students. The scale of our teaching is very large compared with some other divisions, where research and clinical activities take priority. In terms of academic league tables on undergraduate provision we consistently receive high ratings, in Psychology and Linguistics, UCL is always in the top 10. We have recently seen the publication of the results of the Research Assessment Exercise and our outstanding research has been suitably recognised, we are the top-rated centre for psychology in the country, emerging ahead of Cardiff, Birmingham, and Oxford, based on volume of high-quality research. 75% of our research in psychology was judged to be world-leading or internationally excellent. Our research in speech, language and communication was ranked 3rd nationally in Allied Health Professions; linguistics was ranked 6th; computer sciences 5th, and neuroscience 2nd; overall our Division ISSUE 3 APRIL 2009 SLMS PEOPLE received outstanding results and staff should be proud of this achievement. What are your priorities as head of the Division? We’ve been through complex reorganisation in Life Sciences. For us a major element of that has been the reorganisation of support staff in to teams in areas like Finance and HR, which has been a very welcome move. I think it considerably improves the management and career opportunities for our support staff as well as providing us with continuing first rate support services. Having gone through this lengthy period or reorganisation we are very keen, over the next year or two, to make sure we take full advantage of that, ensuring consolidation of what has been done – that covers a range of more specific topics, like our web presence. We have an enormous amount of work to do to make sure that that we are providing an absolutely top notch web presence to the outside world and internally to our staff and students, we are putting a considerable amount of effort in to that. On the teaching front the College strategy is not to expand undergraduate programmes but to look for opportunities for improvements at graduate level. We would like to continue to develop the availability of psychology and language science modules for students of other faculties. Making these modules more readily available to those taking interdisciplinary courses like the Biomedical Sciences degree or the Natural Sciences degree, this is really interesting for us because, for example, the natural sciences students are particularly numerate and there are elements of psychology and language (vision research or some neuroscience aspects) which are extremely mathematical so teaching those kinds of students is very interesting. But at undergraduate level we are not envisioning major developments in the future. Our PhD, research, and professional training programmes, are all heavily accredited and that keeps us very much on our toes, but again, we are not envisioning massive changes other than to make sure that at all times the quality is as high as we can possibly make it. Where we are looking at future developments is at masters’ level. We launched an MSc three years ago in Cognitive and Decision Sciences. Decision making, for example, is of interest not just in psychology but also in the law faculty, statistics, computer sciences, and in economics. This programme has exceeded all our expectations and has been extremely successful, it is now in it’s third year and has about 30 students, a large group from over seas, and the quality of students is absolutely extraordinary. That has been a path finding MSc for us and although there is a lot of work involved in running these MSc’s, of course they do have great research spin offs because the students are doing significant components of research in a PIs laboratory and it is cutting edge. So we are looking with some attention at other areas in Psychology and Language Sciences were we feel there is a market for similar programmes and where we believe student interest would be high - across the whole discipline. Financial stability will be one of our priorities. The College finances are turbulent at best, and our finances have been rocky, with planning developments, constant changes to the financial model and significant changes to the funding mechanisms, we would very much hope that over the next three years things calm down a little bit in terms of financial planning and stability. Tell us about your career to date? My career started at Cambridge, I was an undergraduate and then a PhD student in Psychology. I worked in an MRC Psychology Unit in Cambridge UCL SCHOOL OF LIFE AND MEDICAL SCIENCES for my first post doctoral job before a spell as a post doc at the University of San Diego. I came to UCL in 1992 and I became head of the Department of Psychology seven years ago. My own research area is cognitive psychology and in particular learning, memory and decision making. One of the major research developments for me over the last decade has been the ESRC Centre for Economic Learning and Social Evolution, which is a joint centre between psychology and economics and with substantial input from other departments, such as mathematics and anthropology. Although that centre is coming towards an end now it has been absolutely fundamental in UCL’s development of areas of research both from the point of view of psychology of decision making but also in terms of major topics in public policy, particularly on the economics side, where the centre has been involved in many high profile areas of public policy debates. As a spin off from that UCL has now become one of the world centres in the very topical area of neuroeconomics – the interface between the brain, decision making rationality, behaviour and so on. My recent book, The Psychology of Decision Making (Hove, UK: Psychology Press), a collaborative effort with Ben R Newell and David A Lagnado, came out a year ago. I’ve had long term collaborations with colleagues in Spain (Malaga and Granada), Germany (University of Marburg), and Australia (University of New South Wales). What are your career highlights? I’m very proud of substantial research facilities that we have been able to provide and/or refurbish in neuroscience and Continued on page 23 ISSUE 3 APRIL 2009 21 SLMS PEOPLE New appointments from 1st January – 28th February 2009 Gatsby Computational Neuroscience Unit at UCL Ms Reign Macmillan, Administrative Manager. MRC Laboratory for Molecular Cell Biology Dr Benjamin Baum, Senior Cancer Research Fellow; Dr Robertus De Bruin, Career Development Fellow; Dr Patricia Kunda, Research Associate; Dr Oscar Lancaster, Research Associate; Mr Tao Liu, Research Associate; Dr Petra Mlcochova. UCL Division of Biosciences Mr Alexandr Arenz, Research Associate; Dr Reshma Baliga, Research Associate; Ms Clarissa Bradley, Research Assistant; Ms Anne Cantarella, Research Associate; Miss Charmian Dawson, Teaching Fellow; Miss Catherine Ingram, Research Associate; Dr Vincent Cibert-Goton, Research Associate; Dr John Kirkpatrick, Biomolecular NMR Spectroscopist; Dr Shivanthi Manickasingham, Administrator; Dr Samuel Marguerat, Research Associate; Dr Vera Pancaldi, Research Associate; Ms Jigna Patel, Research Technician; Dr Matthew Sanders, Research Associate; Dr Eugene Schuster, Senior Research Fellow; Dr Matina Tsalavouta, Research Associate. UCL Cancer Institute Mr Robert Harvey, Research Technician; Ms Catherine Miles, Director of Development: Cancer Institute Research Trust; Dr Jonathan Hasleton, Clinical Research Fellow; Dr Derek Hausenloy, Consultant Cardiologist; Miss Elizabeth 22 Spencer, Centre Administrator; Dr Michael Chapman, Clinical Reserach Fellow; Ms Yin Ku, Research Assistant; Miss Hannah Poulsom, Miss Mi Zhou, Research Associate; Dr Bernard Khoo, Senior Lecturer/ Honorary Consultant in Endocrinology; Dr Oliver Staples, Research Associate; Miss Ira Jakupovic, TTP Data Manager/ Trial Co-ordinator; Ms Konstantina Kallinikou, Research Technician; Dr Deepika Kassen, Research Associate; Mr Jo Edward Lewis, Research Technician; Miss Lucy Young, Research Technician; Miss Sultana Begum-Rahman, Trials Assistant; Mr Edward Blandford, Trial Co-ordinator; Ms Elizabeth Chang, Trials Assistant; Miss Sally Frampton, Trials Assistant; Mr Anthony Lawrie, Trials Assistant; Ms Dymphna Lee, Data Manager; Mr Colin Lunt, Senior Data Manager; Ms Jaymi Patel, Trial Co-ordinator; Ms Bilyana Popova, Trial Co-ordinator; Mr Jochim Sassmann, Trial Co-ordinator; Ms Milena Toncheva, Data Manager. UCL Division of Infection & Immunity Ms Ruthie Birger, Mr Steven Prideaux, Research Assistant; Dr Stephen Toovey, Principal Clinical Research Associate. UCL Division of Medical Education Ms Anushka Leslie, Administrator. UCL Division of Medicine Dr Samuel Janes, Clinical Consultant; Mr Darren Foard, Clinical Research Nurse; Miss Naomi Leatham, Deputy Divisional Manager; Miss Joan Maudsley, Infection Control Research Nurse and Project Co-ordinator for the I-STRAT Study; Ms Charis Pericleous, Research Assistant; Miss Eleanor Pyart, Senior Clinic Co-ordinator; Ms Ivana Slamova, Research Technician; Mr Graham Wright, Research Assistant. UCL Division of Population Health Miss Kelly Lawless, Finance and HR Administrator; Dr Charlotte WarrenGash, MRC Fellowship; Dr Laura UCL SCHOOL OF LIFE AND MEDICAL SCIENCES Broomfield, Research Associate; Miss Alison Fildes, Administrative Research Support Officer; Miss Abigail Fisher, Research Associate; Miss Corrinne Frazzoni, Administrator; Dr Benjamin Gardner, Lecturer in Health Psychology; Dr Xin Mao, Senior Clinical Research Associate; Mrs Joanna Phillips, Research Nurse; Mrs Lubei Begum Ali, Research Assistant; Ms Shajeda Dewan, Research Assistant; Miss Harriet Ferner, Research Assistant; Ms Amanda Holman, Senior Research Associate; Miss Louise Owen, Research Assistants; Dr Sally Sharp, Research Associate; Ms Mary Apps, Assistant Project Co-ordinator; Dr Sophie Eastwood, Senior Clinical Research Associate; Ms Mary Good, Course Administrator- Yr4; Miss Laura Horsfall, Research Associate; Dr Kingshuk Pal, Senior Clinical Research Associate. UCL Division of Psychology & Language Sciences Miss Beth Dumonteil, Unit Administrator; Ms Emma Trustam; Mr Robert Adam, Research Assistant; Mr Jordan Fenlon, Research Associate; Mr Malcolm Ballantine; Mrs Roisin Clarke, Executive Officer; Dr Vikki Janke; Ms Pui-Lai Law, Teaching Administrator; Miss Katharine Mair, Postgraduate Teaching Assistant; Dr Mary Pearce; Dr Marco Tamburelli; Mrs Sonia Theodoric, Divisional Staffing Officer; Dr Jeffrey Beck, Research Associate; Dr Aikaterini Fotopoulou, Teaching Fellow; Ms Manon Mulchuyse; Ms Joanna Parketny, Research Administrator; Dr Emmanuelle Volle, Research Associate; Ms Stefanie Bucher, UCL Teaching Fellow; Ms Fiona Newman, Clinical Co-ordinator; Ms Alexandra Perovic, Teaching Fellow; Ms Claire Scahill, Administrative Assistant. UCL Division of Surgery & Interventional Science Dr Babak Afrough, Research Associate; Miss Janice Tsui, Academic Clinical Consultant; Dr Jayant Vaidya, Clinical Senior Lecturer; Miss Hedeer Jawad, Research Assistant. ISSUE 3 APRIL 2009 SLMS PEOPLE UCL Division of Research Strategy Ms Manavi Tyagi, Research Assistants. UCL Ear Institute Dr Lucy Anderson, Research Associate; Dr Bradford Backus, Research Associate. UCL Eastman Dental Institute Mr Robert Blizard, Dr Alon Preiskel, Clinical Teaching Fellow; Mr Robert Stone, Senior Clinical Teaching Fellow; Dr Alexandra Efthymiou, Clinical Teaching Fellow. UCL Institute for Women’s Health Mr Stephane Camuzeaux, Research Associate; Dr Tamara Davies, Research Co-ordinator; Ms Marcia Jacks, Institute Manager; Dr Dorottya Kelen, Research Assistant; Dr Alice Len, Research Associate; Ms Gergana Metodieva, Research Technician; Ms Judy Okello, Senior Staffing Administrator; Miss Emily Rothwell, PA/ Office Assistant; Mr William Stott, Research Associate. UCL Institute of Child Health Ms Sofia Lampropoulou, Research Physiotherapist; Mr Mark Bishay, Clinical Research Associate; Miss Emanuela Falaschetti, Statistician; Miss Stephanie Kumpunen, Research Assistant; Mr Philip Hennis, Research Technician; Mr Alasdair O’Doherty, Research Technician; Mr Benjamin Wheeler, Research Assistant; Dr Samir Ounzain, Research Associate; Dr Maria Joannou, Research Associate; Dr Karen Price, Research Associate; Mrs Julie Lewis, PA/Unit administrator; Miss Sophia Penny, Research Assistant; Dr Mara Cananzi, Experimental Officer; Miss Deborah Briggs, Research Assistant; Ms Antonia Houweling, Senior Research Associate; Ms Joanna Morrison, Research Associate; Miss Lucinda CashGibson, Research Assistant; Miss Sanja Stanojevic, Research Associate; Miss Sarah Tempany, Personal Assistant; Miss Kim Dunaway, Assistant Accounts Officer/ Charitable Trusts Assistant. UCL Institute of Neurology Dr Helen Ling, Senior Clinical Research Associate; Mr Mateen Shaffi, IT Support Assistant; Mrs Sharon Goering, IT Support Assistant; Dr Anna-Elisabetta Vaudano, Clinical Research Associate (Maternity Cover); Dr Arnab Ghosh, Clinical Research Associate; Dr Ahmed Toosy, Clinical Senior Lecturer; Mr Matthew Lawrence, Research Assistant; Dr Verity Leeson, Raymond Way Research Fellow; Dr Frank Scharnowski, Marie Curie Intra- European Career Development Fellowship; Ms Isabel Stromboni, Receptionist; Ms Victoria Castleman, Research Technician; Dr Parashkev Nachev, Clinical Training Fellow (Walport Lecturer); Dr Otto Bjoertomt, Research Associate; Dr Mahaleskshmi Desikan, Clinical Research Associate; Dr Gosala Gopalakrishnan, Cohort Manager; Ms Kate Macdonald, Research Assistant; Dr Ashwani Jha, Research Associate. UCL Institute of Ophthalmology Miss Pranita Gandhi, Research Technician; Dr Clemens Lange, Clinical Research Associate; Miss Hannah Roche, Research Assistant; Miss Kavitha Thayaparan, Research Associate; Miss Erika Halaszova, Laboratory Manager; Dr Shazeen Hasan, Research Associate; Dr Aki Kato, Dr Hannah Levis, Research Associate. UCL Medical School Management Mrs Julia Richardson, Assistant Administrative Officer. Wolfson Institute of Biomedical Research at UCL Ms Joanna Andryszkiewicz, Research Associate; Dr Ah Chan, Research Associate; Dr Soraya Diez Posada, Research Associate; Dr Amos Folarin, Research Associate; Ms Chrysanthia Leontiou, Research Associate; Dr Ariadna Mendoza-Naranjo, Senior Research Associate; Mr Helin Zhuang, Research Technician; Dr Aliakmal Momin, Research Associate; Mr Conrad Vink, Research Associate. UCL SCHOOL OF LIFE AND MEDICAL SCIENCES people news in brief Developmental Science Early Career Researcher Prize Dr Essi Viding won the Developmental Science Early Career Researcher Prize for her paper: Viding, E., Jones, A., Frick, P., Moffitt, T., & Plomin, R. (2008). Heritability of antisocial behaviour at 9: Do callous-unemotional traits matter? Developmental Science, 11(1), 17-22. This prize recognises the emergence of new researchers with outstanding potential in the field of developmental sciences. Professor Martin Birchall Professor Martin Birchall joined the Ear Institute in January after winning this year’s Science and Technology category in the Morgan Stanley/Daily Telegraph Great Britons awards. He received the accolade for leading the team who created and transplanted the first organ to be grown from stem cells. Continued from page 21 in particular the creation of a neuroimaging centre in the Bedford Way building to complement the neuroimaging facilities in Queen Square. It is a joint facility that we run with Birkbeck, called BUCNI, based around an MRI scanner. It gives psychology researchers access to neuro-imaging methods. I’m also proud of the Institute of Behavioural Neuroscience under Kate Jeffery’s Directorship, based on the refurnished fifth floor of the Bedford Way Building, is a state of the art facility for animal behavioural neuroscience. ISSUE 3 APRIL 2009 23 EVENTS ACADEMIC EVENTS Listed below are details a small selection of SLMS events. As these events are subject to change, it is always advisable to confirm details in advance with the named contact. A full listing of SLMS events is available on the website: www.ucl.ac.uk/slms/ 15 April 24 April 7 May DCNU Memory & Communication Seminar Series ‘Brain structure and language processing: individual differences and expertise-related plasticity’ Dr Narly Golestani (UCL Institute of Cognitive Neuroscience) UCL Research Department of Cell & Developmental Biology ‘The Interplay of Notch Wnt and Shh in Mesoderm Development in the Developing Chick Embryo’ Dr Kim Dale (Cell & Developmental Biology, University of Dundee) UCL Research Department of Cell & Developmental Biology ‘The mechanism of Neural Crest cell emigration coupled to early fate restrictions’ Professor Chaya Kalcheim Time / location: 16.30, Room C 2nd floor Wellcome Trust Building, UCL Institute of Child Health, 30 Guilford Street, WC1N 1EH Free admittance, with no need to pre-book. 22 April Wellcome Trust Centre for the History of Medicine ‘Matters of the Heart, Or Why the Heart Matters: Emotions, the Body and Medical History’ Dr Fay Bound Alberti (Queen Mary, University of London) Time / location: 16.30–18.00 (doors open/refreshments at 4pm), 183 Euston Road Registration not required Further information: www.ucl.ac.uk/ histmed/events Time / location: 16.00 JZ Young Lecture Theatre Contact: Glenda Young; +44 (0)20 7679 3346 Further information: www.cdb.ucl. ac.uk/seminars/special.shtml 6 May Wellcome Trust Centre for the History of Medicine ‘Qi or Blood Circulation? Rashid al-Din’s Ilkhan Treasure Book on Chinese Science and Techniques’ Dr Wang Yidan (Peking University) and Dr Vivienne Lo (Wellcome Trust Centre for the History of Medicine at UCL) Time / location: 13.00–14.00pm (doors open at 12.45pm), 183 Euston Road Registration not required Further information: www.ucl.ac.uk/ histmed/events Time / location: Dept of Anatomy and Cell Biology, Hebrew University of Jerusalem Contact: Glenda Young; +44 (0)20 7679 3346 Further information: www.cdb.ucl. ac.uk/seminars/special.shtml Credits Editor: Fleur Adolphe Design: UCL Medical Illustration, ICH/GOSH gdesign@ich.ucl.ac.uk Articles for the SLMS Newsletter: We welcome articles from members of SLMS. Please send copy for the next issue to the Communications Manager (tel: 020 7679 6944 or email: slms-editor@ucl.ac.uk) by 5 May 2009 Launch Event of the UCL Centre for Stem Cells and Regenerative Medicine Friday, 24 April (10.30 to 15.30) at the JZY Lecture Theatre, Anatomy building, in Gower St. 24 The opening ceremony will include welcome addresses by: Edward Byrne, Vice-Provost for Health, Executive Dean UCL Faculty of Biomedical Sciences Peter Mobbs, Executive Dean UCL Faculty of Life Sciences Ian Jacobs, Dean, Health Sciences Research UCL & Partners Claudio Stern, Chair, UCL Centre for Stem Cells and Regenerative Medicine Steering Committee, Research Department of Cell and Developmental Biology, Division of Biosciences Chairmen: John Martin, UCL Division of Medicine (recipient of the 2008 European Society of Cardiology Gold Medal) Chris Mason, UCL Department of Biochemical Engineering Confirmed UCL speakers in alphabetical order: • Martin Birchall (UCL’s first Professor of Laryngology, UCL Ear Institute, and winner of Morgan Stanley/’ ‘Daily Telegraph’ 2008 Great Britons (Scientific and Innovation category) • Jeremy Brockes (UCL Department of Structural and Molecular Biology and MRC National Institute for Medical Research, awarded the 2008 AAAS Newcomb Cleveland Prize to the outstanding publication in Science uncovering a new molecular cue that promotes limb regeneration in newts) • Pete Coffey (UCL Institute of Ophthalmology and Leader, London Project to Cure Blindness) UCL SCHOOL OF LIFE AND MEDICAL SCIENCES •P aul Riley (UCL Institute of Child Health, recipient of the 2008 European Society of Cardiology Council on Basic Cardiovascular Science Outstanding Achievement Award). Confirmed Invited Keynote Speaker: Giulio Cossu, Fondazione San Raffaele del Monte Tabor, Milano (an expert in transplantation of adult stem cells in Duchenne muscular dystrophy) For catering purposes, we kindly request confirmation of participation by 31st. March Further information: http://www.ucl.ac.uk/ stemcells/events/launch ISSUE 3 APRIL 2009