Title BRITISH SOCIETY FOR HEART FAILURE NATIONAL HEART FAILURE AUDIT APRIL 2011 - MARCH 2012 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 1 1 28/11/2012 14:19 NICOR (National Institute for Cardiovascular Outcomes Research) is a partnership of clinicians, IT experts, statisticians, academics and managers which manages six cardiovascular clinical audits and three clinical registers. NICOR analyses and disseminates information about clinical practice in order to drive up the quality of care and outcomes for patients. The British Society for Heart Failure (BSH) is a national organisation of healthcare professionals which aims to improve care and outcomes for patients with heart failure by increasing knowledge and promoting research about its diagnosis, causes and management. The Healthcare Quality Improvement Partnership (HQIP) is led by a consortium of the Academy of Medical Royal Colleges, the Royal College of Nursing and National Voices. Its aim is to promote quality improvement, and in particular to increase the impact of clinical audit in England and Wales. HQIP hosts the contract to manage and develop the National Clinical Audit and Patient Outcomes Programme (NCAPOP). The programme comprises 40 clinical audits that cover care provided to people with a wide range of medical, surgical and mental health conditions. Founded in 1826, UCL (University College London) was the first English university established after Oxford and Cambridge, the first to admit students regardless of race, class, religion or gender, and the first to provide systematic teaching of law, architecture and medicine. It is among the world’s top universities, as reflected by performance in a range of international rankings and tables. UCL currently has 24,000 students from almost 140 countries, and more than 9,500 employees. Its annual income is over £800 million. Authors Report produced by John Cleland (University of Hull) Henry Dargie (University of Glasgow) Suzanna Hardman (Whittington NHS Trust) Theresa McDonagh (King’s College London) Polly Mitchell (NICOR) Data cleaning and analysis Emmanuel Lazaridis (NICOR) Darragh O’Neill (NICOR) Acknowledgments The National Heart Failure Audit is managed by the National Institute for Cardiovascular Outcomes Research (NICOR), which is part of the National Centre for Cardiovascular Prevention and Outcomes, based at University College London. The National Heart Failure Audit is funded and commissioned by the Healthcare Quality Improvement Partnership (HQIP). Specialist clinical knowledge and leadership is provided by the British Society for Heart Failure (BSH) and the audit’s clinical lead, Professor Theresa McDonagh. The strategic direction and development of the audit is determined by the audit Project Board. This includes major stakeholders in the audit, including cardiologists, the BSH, heart failure specialist nurses, clinical audit and effectiveness managers, cardiac networks, patients, NICOR managers and developers, and HQIP. This report was completed in close collaboration with the NICOR technical team, formerly known as the Central Cardiac Audit Database (CCAD). Marion Standing has again been especially involved. We would especially like to thank the contribution of all NHS Trusts, Welsh Heath Boards and the individual nurses, clinicians and audit teams who collect data and participate in the audit. Without this input the audit could not continue to produce credible analysis, or to effectively monitor and assess the standard of heart failure care in England and Wales. This report is available online at www.ucl.ac.uk/nicor/audits/heartfailure/additionalfiles National Heart Failure Audit National Institute for Cardiovascular Outcomes Research (NICOR) Institute of Cardiovascular Science, University College London 3rd floor, 170 Tottenham Court Road, London W1T 7HA Tel: 0203 108 3927 Email: polly.mitchell@ucl.ac.uk National Heart Failure Audit April 2011-March 2 Published 27th November 2012. The contents2012 of this report may not be published or used commercially without permission HF Report 2012 Design B.indd 2 28/11/2012 14:19 National Heart Failure Audit April 2011 - March 2012 The fifth annual report for the National Heart Failure Audit presents findings and recommendations based on patients discharged with a diagnosis of heart failure between 1 April 2011 and 31 March 2012, covering all NHS Trusts in England and Health Boards in Wales which admit acute heart failure patients. The report is aimed at those involved in collecting data for the National Heart Failure Audit, as well as clinicians, healthcare managers, clinical governance leads, and all those interested in improving the outcomes and well-being of patients with heart failure. The report includes clinical findings at national and local levels and patient outcomes for the audit year. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 3 3 28/11/2012 14:19 Contents The Authors 2 Contents 4 List of figures Readmission 15 Aetiology 16 5 Symptoms 16 Foreword 6 Aetiology 16 1. Executive summary 7 Diagnosis 16 Echocardiography 16 Diagnosis 17 Treatment on discharge for LVSD 17 ACE inhibitor and ARB 17 Beta blocker 17 MRA 17 Loop diuretics 17 Thiazide diuretics 17 Digoxin 17 Treatment on discharge by age 17 Monitoring heart failure patients 18 Follow-up services 18 Palliative care 18 Analysis by hospital 19 Participation and case ascertainment 19 Clinical practice 30 1.1 National Heart Failure Audit 7 1.2 Findings 7 Participation 7 Hospitalisation 7 Diagnosis 7 Treatment 7 Referrals on discharge 7 Hospital level analysis 7 In-hospital mortality 8 Mortality for survivors to discharge 8 Recommendations 8 1.3 2. Introduction 3.6 3.7 3.8 3.9 2.1 Heart Failure 10 2.2 The role of the audit 10 2.3 National use of audit data 10 2.4 Organisation of the audit 11 2011/12 in-hospital mortality 42 2.5 The scope of the audit 11 2011/12 post-discharge mortality 42 2.6 The database 11 2.7 Data collection and IT 11 2.8 Improving our IT platform 12 2.9 Improving analysis 12 3. Findings 13 3.1 Data cleaning and data quality 13 3.2 Participation 13 Number of Trusts 13 Number of patients 14 Case ascertainment 14 Demographics 14 Age 14 Age and sex 14 Age and Index of Multiple Deprivation 14 3.3 3.4 4 10 3.5 3.10 Mortality 3.11 Three-year trends 42 47 Three-year in-hospital mortality 47 Three-year post-discharge mortality 47 4. Case studies 51 4.1 Improving clinical practice and patient outcomes 51 4.2 Using data to drive improvement 51 4.3 An example of local practice in conducting the 51 national Heart Failure Audit 4.4 The national perspective 5. Research use of National Heart Failure 51 54 Audit data 6. Conclusions Demographics 15 6.1 In-hospital care 15 6.2 Length of stay 15 55 Quality of care and patient outcomes 55 Data completeness and participation 55 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 4 28/11/2012 14:19 7. Appendices A1 National Heart Failure Audit Project Board 56 56 membership A2 HALO Group 56 A3 Data for 2011/12 mortality analysis 56 A4 Data for 2009-12 mortality analysis 58 A5 Glossary 59 8. References 61 List of figures and tables Figure 14 Post-discharge survival by prescription of beta blockers on discharge for patients with LVSD 45 Figure 15 Post-discharge survival by prescription of beta blockers on discharge (all patients) 45 Figure 16 Post-discharge survival by prescription of loop diuretics on discharge for patients with LVSD 45 Figure 17 Post-discharge survival by prescription of loop diuretics on discharge (all patients) 46 Figure 18 Post-discharge survival by additive drug treatment on discharge for patients with a diagnosis of LVSD 46 Figure 19 Post-discharge survival by referral to cardiology follow-up services 46 46 48 Table 1 Records excluded from analysis in this report 13 Figure 20 Post-discharge survival by referral to heart failure liason follow-up services Table 2 Records excluded from mortality analysis in 13 Table 9 this report Figure 1 Age at first admission by sex Figure 2 The effect of deprivation on age of first admission 15 Figure 3 Mean length of stay by hospital 15 Figure 4 Median length of stay by hospital 15 Figure 5 Number of readmissions in 2011/12 16 Table 3 Previous medical history and diagnosis of LVSD 16 Figure 6 Treatment for LVSD on discharge by age 18 Table 4 Participation and case ascertainment in England 19 Table 5 Participation and case ascertainment in Wales 29 Table 6 Clinical practice in England (2011/12) 30 Table 7 Clinical practice in Wales (2011/12) 41 Table 8 Cox proportional hazards model for post- 43 14 discharge mortality (2011/12) Figure 7 Overall post-discharge survival 43 Figure 8 Post-discharge survival by sex 43 Figure 9 Post-discharge survival by age at admission 44 Figure 10 Post-discharge survival by place of care 44 Figure 11 Post-discharge survival by presence or 44 absence of LVSD Figure 12 Post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge for patients with LVSD 44 Figure 13 Post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge (all patients) 45 Cox proportional hazards model for post-discharge mortality (2009-12) Figure 21 Three-year post-discharge survival (2009-12) 48 Figure 22 Three-year post-discharge survival by sex (2009-12) 48 Figure 23 Three-year post-discharge survival by age (2009-12) 48 Figure 24 Three-year post-discharge survival by place of care (2009-12) 49 Figure 25 Three-year post-discharge survival by presence 49 or absence of LVSD (2009-12) Figure 26 Three-year post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge in patients with LVSD (2009-12) 49 Figure 27 Three-year post-discharge survival by prescription of beta blockers on discharge in patients with LVSD (2009-12) 49 Figure 28 Three-year post-discharge survival by prescription of loop diuretics on discharge in patients with LVSD (2009-12) 50 Figure 29 Three-year post-discharge survival by additive drug treatment on discharge in patients with LVSD (2009-12) 50 Figure 30 Three-year post-discharge survival by referral to cardiology follow-up services (2009-12) 50 Figure 31 Three-year post-discharge survival by referral 50 to heart failure liason follow-up services (2009-12) National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 5 5 28/11/2012 14:19 Foreword The ability of high quality national audit data to improve clinical cardiovascular care and its role in delivering important outcome benefits has already been well demonstrated through initiatives such as MINAP (Myocardial Ischaemia National Audit Project). However, heart failure remains one of the biggest challenges for modern cardiovascular care and an area where robust audit data has major potential to inform change for the benefit of patients. The National Heart Failure Audit 2011/2012 highlights the importance of heart failure which affects around 900,000 individuals in the UK, accounts for 5% of all emergency hospital admissions and utilises 2% of all NHS hospital bed days. It is associated with a high annual mortality, especially if poorly treated, and the effect of heart failure on quality of life cannot be underestimated. Yet optimal management can result in a better prognosis with fewer symptoms and an increased life expectancy. The National Heart Failure Audit, now in its sixth year, has evolved to include data on acute heart failure admissions from 90% of the Trusts and Health Boards in England and Wales and now represents 59% of all heart failure admissions. It provides a valuable insight into the diversity of both management and outcomes, highlighting the importance of specialist care, optimising medical therapy and appropriate specialist follow-up as key indicators of improved mortality. Although in-hospital mortality remains high at 11.1% the differences between specialist and non-specialist care are striking, with 7.8% in-hospital mortality for patients managed under cardiology care versus 13.2% mortality under general medicine and 17.4% for those managed in other wards. 6 The additional mortality benefits of specialist follow-up by cardiology and heart failure teams also highlight the importance of integrated care beyond hospital admission. These insights into the significant outcome gains possible through evidence based, specialist delivered management are a powerful vehicle for driving up quality, addressing variations in care, and for planning and commissioning of future heart failure services. The National Heart Failure Audit is managed by the National Institute for Cardiovascular Outcomes Research (NICOR), receiving clinical direction and leadership from the British Society for Heart Failure which, along with the clinical teams managing the patients and all those submitting the data, deserves enormous credit for its development and continued evolution. From April 2013, when hospitals will be required to submit data on all heart failure admissions, the increasing importance of this audit in driving up the quality of heart failure management will be further enhanced. Dr Iain A Simpson President, British Cardiovascular SocietyChair, British Cardiovascular Society National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 6 28/11/2012 14:19 1 Executive Summary Heart failure is a highly prevalent condition, often with poor outcomes: an estimated 900,000 people in the U.K. have heart failure and over a third will die within a year of diagnosis. Despite an elderly patient group, many of whom have extensive comorbidities contributing to or complicating their heart failure, good clinical management has been shown to substantially improve patient outcomes. Overall mean length of stay was 13.1 days on first admission and 13.4 days on readmission. This is an increase from last year’s audit (11 days on admission and 13 days on readmission). In contrast to last year, when cardiology patients had longer lengths of stay than patients treated on other wards, in 2011/12 cardiology patients had shorter lengths of stay (12.7 days) than patients on general medical wards (13.1 days) and those on other wards (14.7 days). 1.2.3 Diagnosis 1.1 National Heart Failure Audit The National Heart Failure Audit was established in 2007 to monitor the care and treatment of patients admitted to hospital in England and Wales with heart failure. The audit reports on the clinical practice and patient outcomes of acute patients discharged from hospital with a primary diagnosis of heart failure. The audit collects data based on recommended clinical indicators with a view to driving up standards by encouraging the implementation of guideline recommendations and reporting on practice statistics and outcomes. Audit data is used by a number of national groups, including the NHS Information Centre, the Care Quality Commission and data.gov.uk. However improvements in standards of care depend on participating hospitals using and reviewing their own data to change and improve practice. The audit is strongly supported by the British Society for Heart Failure and is one of six cardiovascular audits managed by NICOR, part of the National Centre for Cardiovascular Prevention and Outcomes at UCL. The audits are funded and commissioned by HQIP. 1.2 Findings 1.2.1 Participation Between April 2011 and March 2012 142 out of 155 NHS Trusts in England and Health Boards in Wales (92%) submitted data to the audit. 12 NHS Trusts and one Health Board did not submit any data to the audit. After data cleaning, the total number of records in the 2011/12 audit was 37,076, made up of 32,906 index admissions and 4,170 readmissions within the audit period. Nationally the audit represents 59% of all heart failure patients in England and Wales. Case ascertainment was 62% for England and 12% for Wales. 1.2.2 Hospitalisation 48% of patients were treated in cardiology wards, with 41% treated on general medical wards and 11% on other wards. Men were far more likely to be treated on cardiology wards than women, as were younger patients. The use of echocardiography remains high, with 86% receiving an echo during the admission. 1.2.4 Treatment Prescription rates of disease modifying treatments at discharge for patients with left ventricular systolic dysfunction (LVSD) remain broadly similar to those recorded in the 2010/11 audit. Prescription of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARB) remains high, with 84% of patients discharged on either of the therapies (81% in 2010/11). Prescription of some recommended therapies increased: 78% of patients were prescribed beta blockers on discharge, compared to 65% in 2010/11. 45% of patients were discharged on a mineralocorticoid receptor antagonist (MRA), an increase from 36% in 2010/11. Some of the apparent increase in prescribing between years may be accounted for by changes in analytical method. As observed in previous years, prescription rates for ACE inhibitors/ARBs, beta blockers and MRAs are all higher when patients are admitted to cardiology wards, as opposed to general medical or other wards. 1.2.5 Referral on discharge 54% of patients were referred to a heart failure liaison service on discharge, and 52% to cardiology follow-up. Referral rates were higher for patients who were younger, male and treated on a cardiology ward. 1.2.6 Hospital level analysis For the first time, the National Heart Failure Audit includes analysis on clinical practice at a hospital level, for all hospitals which submitted at least 100 patient records (or more than 70% of their Hospital Episode Statistics (HES) recorded heart failure admissions) to the audit. The findings show fairly wide variation in clinical practice between hospitals, but it is unclear how representative the patients in the audit are of the heart failure patient population at many hospitals, due to the small number of returns. As of April 2013, hospitals will be required to enter data on all of their heart failure patients, and this will hopefully give a more accurate picture of the variation in the treatment and management of heart failure at a hospital level. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 7 7 28/11/2012 14:19 1.2.7 In-hospital mortality In hospital mortality remains high, with 11.1% of patients discharged in 2011/12 dying during their admission, similar to the 11.6% recorded in 2010/11. These findings are higher than in-hospital mortality rates reported by other European registries,1 and this is likely to reflect the more comprehensive approach taken by the National Heart Failure Audit. In-hospital mortality rates were 7.8% for patients treated on cardiology wards, compared with 13.2% for those treated on general medical wards and 17.4% for those on other wards. The benefit of treatment in a cardiology ward persists when these findings are adjusted for confounding factors such as age and New York Heart Association (NYHA) class. These findings are similar to previous years’ results, and highlight the benefits of specialist treatment. 1.2.8 Mortality for survivors to discharge Of those patients who survived to discharge, 26% died within the follow-up period. Outcomes were significantly better for patients treated on cardiology wards (22%) compared to those treated on general medical wards (30%) and other wards (33%). Mortality rates with key medical treatment (ACEI/ ARBs, beta blockers, MRAs) were substantially lower than without such therapy. The benefits of disease modifying treatment were present in patients with diagnosed with non-systolic heart failure as well as patients with left ventricular systolic dysfunction when taken alone. Patients discharged from cardiology wards were more likely to be prescribed these drugs. The benefits of disease modifying therapies were additive. Patients discharged on all of ACEI/ARBs, beta blockers and MRAs had better survival outcomes than patients prescribed an ACEI/ARB and a beta blocker but no MRA, and patients prescribed an ACEI/ARB alone. All of these patients had substantially lower mortality than patients discharged on none of the three therapies. Patients referred to heart failure nurse and cardiology followup services also had better survival, only 20% of patients referred to cardiology follow-up services on discharge died, compared with 32% of patients not referred to follow-up with a cardiologist. 25% of patients referred to heart failure nurse liaison services within the audit year died, compared with 28% of those not referred to nurse led follow-up. Cox proportional hazards models appear to show that even with adjustment for age, severity of symptoms and history of acute myocardial infarction, for patients who survived to discharge, those not prescribed ACE inhibitors/ARBs and beta blockers on discharge had higher mortality rates. Patients prescribed loop diuretics on discharge had increased mortality 8 rates following adjustment for these confounding factors. After adjusting for possible differences in patient characteristics, patients who were not managed on cardiology wards and those who did not receive cardiology follow-up continued to have higher mortality rates. (The analysis was adjusted for the following covariates: age>75, NHYA class III/IV, previous AMI, no ACEI/ARB, no beta blocker, loop diuretic, no cardiology follow-up, not treated on cardiology ward). Mortality analyses for the three year period between April 2009 and March 2012 show similar findings. 42% of patients who survived to discharge died during this period, but optimal treatment and management in hospital had beneficial effects on patient outcomes, which continued long after discharge. 1.3 Recommendations The National Heart Failure Audit provides key information to improve outcomes in acute heart failure, one of the great unmet needs in the management of the condition. Considerable progress has been made in case ascertainment since the audit began. The aim now should be to strive for inclusion of all patients admitted to hospital with a primary diagnosis of heart failure to ensure a more representative dataset. The following recommendations are made based on the findings of the audit in this and previous years: This audit has consistently shown that specialist cardiology care and follow up is associated with better outcomes for patients with heart failure even after adjusting for age, severity and other observed differences in patient characteristics. Trusts should ensure that patients with a primary diagnosis of heart failure have specialist input to their care as proposed in NICE guidelines and are managed on cardiology or wards specialising in heart failure wherever feasible. Implementation of key evidence-based medicine i.e. the use of ACE inhibitors, beta blockers and MRAs for those with systolic dysfunction is associated with much improved patient outcomes. Trusts need to concentrate on getting these cornerstone therapies initiated in hospital, wherever possible. Robust arrangements for the optimisation of therapy for cardiac dysfunction via cardiology follow-up, heart failure liaison services and primary care need to be firmly in place prior to discharge. The next phase of the audit will address this discharge planning phase more specifically. As access to specialist medical and nursing care is the gatekeeper to optimal care for heart failure patients, Trusts should ensure that key personnel are in place to deliver this care. The audit also shows that outcome is poorer for patients without, compared to those with, left ventricular systolic dysfunction (LVSD). This likely reflects the greater age of National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 8 28/11/2012 14:19 patients who do not have LVSD but other possibilities will be explored by the audit group. The continuing increase in case ascertainment coupled with data already accrued from previous audits will provide a robust basis for these aims and should be a focus of interest for subsequent audit reports. In 2011 the National Institute for Health and Clinical Excellence produced a quality standard for chronic heart failure, comprising 13 statements summarising the optimal and recommended management of heart failure.2 Hospitals should adhere to these standards in the treatment and care of heart failure patients, with the following statements being particularly relevant: Statement 7: People with chronic heart failure due to left ventricular systolic dysfunction are offered angiotensinconverting enzyme inhibitors (or angiotensin II receptor antagonists licensed for heart failure if there are intolerable side effects with angiotensin-converting enzyme inhibitors) and beta-blockers licensed for heart failure, which are gradually increased up to the optimal tolerated or target dose with monitoring after each increase. Statement 10: People admitted to hospital because of heart failure have a personalised management plan that is shared with them, their carer(s) and their GP. Statement 11: People admitted to hospital because of heart failure receive input to their management plan from a multidisciplinary heart failure team. Statement 12: People admitted to hospital because of heart failure are discharged only when stable and receive a clinical assessment from a member of the multidisciplinary heart failure team within 2 weeks of discharge. Statement 13: People with moderate to severe chronic heart failure, and their carer(s), have access to a specialist in heart failure and a palliative care service. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 9 9 28/11/2012 14:19 2 Introduction 2.1 Heart Failure Heart Failure is a complex clinical syndrome characterised by the reduced ability of the heart to pump blood around the body. It is caused by structural or functional cardiac abnormalities, including previous myocardial infarction, cardiomyopathies, valvular heart disease and hypertension. It is thought that around 70% of all heart failure cases are caused by coronary heart disease. Atrial fibrillation and renal dysfunction are common precipitating factors and complications of heart failure, and the condition is characterised by symptoms such as shortness of breath and fatigue, and signs such as fluid retention. Around 900,000 people in the U.K. suffer from heart failure, and this number is set to rise due to an ageing population, improved post-infarction survival rates, and more effective treatments3. In 2007 it was estimated that 1.81% of the population aged 45 years or older suffered from heart failure4. The prevalence of heart failure rises steeply with age, with the British Heart Foundation Statistics Database estimating in 2009 that 13.7% of men and 12.5% of women aged over 75 years in England suffer from the condition5. Heart failure constitutes a large burden on the NHS, accounting for one million inpatient bed-days – 2% of the NHS total – and 5% of all emergency hospital admissions6. Survival rates for heart failure patients who receive suboptimal care are poor. 40% of newly diagnosed patients die within a year,7 and total annual mortality ranges from 10-50%, depending on severity. These figures are supported by the mortality rates reported by the National Heart Failure Audit, which has consistently recorded one-year mortality of around 30% since 2008.8 Heart failure patients can also experience poor quality of life, experiencing pain, dyspnoea (shortness of breath) and fatigue. Heart failure patients also often suffer from mental health problems, with studies showing that over half report low mood, and more than a third suffer from major depression.9 10 These outcomes reflect considerable variation in standards of care: optimal treatment and management of heart failure results in significantly improved prognosis, with fewer symptoms and increased life expectancy. 2.2 The role of the audit National clinical audit is designed to monitor clinical practice and patient outcomes with a view to evaluating hospital performance and driving up standards of care. The National Heart Failure Audit was established in 2007 with the aim of helping clinicians improve the quality of heart failure services and to achieve better outcomes for patients. The audit aims to capture data on clinical indicators which have a proven link to improved outcomes, and to encourage the increased use of clinically recommended diagnostic tools, disease modifying treatments and referral pathways. 10 A series of clinical care standards for heart failure have been developed, including the National Service Framework for Coronary Heart Disease (2000),11 NICE Clinical Guidance for Chronic Heart Failure (2010),12 NICE chronic heart failure quality standards (2011)13 and a standard for delivering heart failure care produced by the European Society of Cardiology Heart Failure Association (2011).14 The audit dataset corresponds to these standards, in order to evaluate the implementation of these existing evidence-based recommendations by hospitals in England and Wales. The audit dataset is regularly reviewed and updated to ensure it is in line with contemporary guidance. 2.3 National use of audit data In addition to this publicly available annual report, the analysis produced by the National Heart Failure Audit are used by national groups with a legitimate interest in the analysis. The NHS Information Centre’s Indicators for Quality Improvement (IQI), a set of indicators developed to describe the quality of NHS service, include participation in the National Heart Failure Audit,15 and the NHS Choices website includes details of participation in the audit in its ‘scorecard’ for Trust performance. Furthermore, the audit currently provides participation rates to the Care Quality Commission’s (CQC) ‘Quality and Risk Profiles’ (QRP),16 a tool used for gathering together key information about NHS organisations, which allows the CQC to monitor compliance with the essential standards of quality and safety. The QRP enable compliance inspectors to assess where risks lie and may prompt front line regulatory activity, such as further enquiries. Clinical audit was one of six key areas raised under the heading ‘NHS’ in the Prime Minister’s Letter to Cabinet Ministers on transparency and open data which stated: Clinical audit data, detailing the performance of publicly funded clinical teams in treating key healthcare conditions, will be published from April 2012. This service will be piloted in December 2011 using data from the latest National Lung Cancer Audit, commissioned by the Healthcare Quality Improvement Partnership (HQIP) as part of the National Clinical Audit and Patient Outcomes Programme (NCAPOP).17 National Heart Failure Audit data will be published on data.gov. uk following the publication of this report in November 2012. There are future plans to provide anonymised National Heart Failure Audit data, at a hospital level, to Cardiac Networks and Clinical Commissioning Groups. An archive of annual audit reports, containing national aggregate data, is also available for download on NICOR’s publicly accessible website. The National Heart Failure Audit had also been published in Heart journal.18 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 10 28/11/2012 14:19 2.4 Organisation of the audit The National Heart Failure Audit is managed by the National Institute for Cardiovascular Outcomes Research (NICOR), and receives clinical direction and leadership from the British Society for Heart Failure. It is overseen by a Project Board which represents key stakeholders, including cardiologists, heart failure nurses, Cardiac Networks and heart failure patients.i The audit is one of six national clinical audits managed by NICOR, part of the National Centre for Cardiovascular Prevention and Outcomes at University College London. These audits are funded by HQIP, which holds commissioning and funding responsibility for 40 national clinical audits in the NACPOP.19 2.5 The scope of the audit The National Heart Failure Audit collects data on acute patients discharged from hospitals in England and Wales with a primary diagnosis of heart failure on discharge, designated by any of the following ICD-10 codes: I11.0 Hypertensive heart disease with (congestive) heart failure I25.5 Ischaemic cardiomyopathy I42.0 Dilated cardiomyopathy I42.9 Cardiomyopathy, unspecified I50.0 Congestive heart failure I50.1 Left ventricular failure I50.9 Heart failure, unspecified Only acute patients should be included in the National Heart Failure Audit, so those patients admitted for elective procedures, for example elective pacemaker implantation or angiography, ought not to be included. Large numbers of these patients being included in the audit has led to several thousand records being deleted from the dataset in the data cleaning process (this is detailed in section 3.1). Participation is currently defined as an NHS Trust or Welsh Health Board submitting a minimum of 20 cases to the audit database each calendar month, or the full number of cases if fewer than 20 patients with heart failure are discharged from the Trust in a month. Participation in the audit has been mandated in the Department of Health’s standard terms and conditions for acute hospital services in 2011/12, covering all acute hospitals in England.20 Participation in the audit has been mandatory for Welsh Local Health Boards since April 2012.21 Although a large proportion of the treatment of chronic heart failure occurs in the community, the National Heart Failure Audit currently only covers acute heart failure admissions to hospital, partly due to IT limitations. The development of a web-based platform for the database in 2013 will make it feasible for community hospitals and other primary care institutions to participate in the audit. 2.6 The database In 2011/12 the dataset contained 38 core fields, covering patient details and demographics, medical history, symptoms, diagnosis, treatment on discharge, referral to follow-up services and place of care in hospital. In March 2011 a revision of the dataset increased the number of core fields to 59. New fields have been added to bring the audit in line with latest NICE guidance,22 23 as well as to ensure that mortality analysis can be adequately risk adjusted to account for known confounding factors. The new fields include input from a multidisciplinary heart failure team, discharge planning, as well as increasing the data collected on medical history, diagnostic tests and follow-up services. These new fields will be included in the analysis in the 2012/13 annual report. 2.7 Data collection and IT User roles vary between hospitals, but the personnel involved in collecting and inputting data tend to be Heart Failure Specialist Nurses, clinical audit leads, and clinical effectiveness managers. Some of the more effective systems of data collection and data entry use nurses or other clinical staff to interpret medical notes and collect data, and clerical staff or clinical audit facilitators to enter it onto the database. This ensures that the data is clinically accurate whilst making optimal use of clinicians’ time. Hospitals are responsible for ensuring that data is entered accurately but the database contains a series of validation checks to ensure that contradictory and clinically improbable data are not entered into the audit. A pro forma, designed to aid data collection, can be downloaded from the NICOR website, along with a set of application notes which defines and explains core data items.24 The application notes will be regularly reviewed to ensure they are clinically accurate and will be amended in response to comments and questions from users to cover frequently asked questions and points of contention. All data are submitted electronically by hospital into a secure central database. To ensure patient confidentiality the database uses advanced data encryption technology and access control through a secure key system. Data can be inputted manually or imported from locally developed systems or third party commercial databases. i. See Appendix 1 for details of project board membership. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 11 11 28/11/2012 14:19 2.8 Improving our IT platform 2.9 Improving analysis Earlier this year NICOR began a major project to upgrade its data collection and management systems. The current Lotus Notes software has become increasingly unwieldy as the NICOR databases have grown in size and complexity. A new platform will substantially improve NICOR’s ability to derive high-quality analyses from the National Heart Failure Audit to inform hospitals, Cardiac Networks and patients regarding the provision of cardiac care. The processes that NICOR uses for analysing National Heart Failure Audit data have also undergone substantial changes this year. Until recently NICOR data were analysed using software and ad hoc analytic codes that were neither consistent nor easy to manage. In preparation for the incorporation of analytic technologies into the new NICOR system, code that was written in SPSS and Excel spreadsheets (for analyses presented in this annual report) was migrated to a standard cross-audit analytic platform based on the R statistical processing language - precise details are available from NICOR. The first step in this project involved a transfer of all data from the NHS Information Centre for Health and Social Care onto secure NICOR servers. This involved re-issuing a new user ID to every database user. The migration was not easy, and it led to some delays in accessing the National Heart Failure Audit. Despite these difficulties, participating hospitals submitted their data on time, making possible the timely publication of this report. We would like to thank everyone for their effort and patience during the migration. The second phase involves the development of a new IT platform which will be rolled out in stages throughout 2013, with the National Heart Failure Audit being the first to be transferred in April. 12 Migration of the National Heart Failure Audit to the new platform for statistical analysis began in August 2012 and continues, with an intended completion date of June 2013. The results presented in this annual report were generated using some, but not all, elements of the new platform. Because the new analytic platform is still under development, with incremental improvements expected over the next few months, the results presented in this report should be considered preliminary and subject to change. Any substantive differences that follow improvements in filtering and more sophisticated statistical modelling of the data will be highlighted in next year’s annual report. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 12 28/11/2012 14:19 3 Findings 3.1 Data cleaning and data quality 3.2 Participation As of 31st June 2012, the total number of records submitted to the National Heart Failure Audit database since 2007 was 137,637. Of these, 41,635 were patients discharged from hospital between 1st April 2011 and 31st March 2012. 3.2.1 Number of Trusts Table 1: Records excluded from analysis in this report Number excluded from full dataset (number excluded from 2011/12 dataset) Admission/ readmission dataset Reason 16 (3) Admission Missing or invalid hospital identifier 8 (5) Readmission Missing or invalid hospital identifier 14 (2) Admission Identical duplicate of another row 67 (2) Readmission Identical duplicate of another row 6 (6) Admission Non-identical rows with duplicate ‘unique’ ID 4268 (299) Admission/ Readmission Time to discharge <0 14204 (3952) Admission/ Readmission Time to discharge 0 or 1 day, and survived to discharge* 1174 (286) Admission/ Readmission Time to discharge 0 or 1 day, and no MRIS life status* 149 NHS Acute Trusts in England and six Health Boards in Wales discharged patients with a coded diagnosis of heart failure in 2011/12, according to HES and PEDW data.iii Out of these 137 NHS Trusts (91.9%) and five Health Boards (83.3%) submitted data to the audit – a total of 91.6% of all eligible institutions. In England 88 of the eligible institutions (64.2%) met the National Heart Failure Audit participation requirements of 20 cases per calendar month, or submitted more than 70% of their HES-recorded heart failure discharges. 70% was chosen as the cut-off point because this was the overall case ascertainment rate aimed for in the 2011/12 audit. A further 37 Trusts (27.0%) submitted less than 70% of their HES figures, but still between 10 and 20 cases per month. In Wales no Health Boards met the participation requirements, and three (50.0%) submitted between 10 and 20 cases per month. The audit has therefore met its participation target of at least 90% of NHS Trusts in England and Health Boards in Wales submitting data to the audit in 2011/12. This marks a significant improvement on the 85% of Trusts taking part in 2010/11. Participation analysis, by Trust, can be found in the hospital level analysis in section 3.7 of this report. No data were submitted by 12 Trusts in England and one Health Board in Wales (those marked with a * have not registered to participate at time of publication): Non-submitting Trusts in England *0 and 1 day admissions who survived to discharge were determined to be outside of the scope of the audit. The National Heart Failure Audit measures acute admissions to hospital, and these patients were deemed very likely to be elective admissions for pacemaker implantation or angiography, and so were excluded from the audit. Patients who had a length of stay of 0 or 1 days and died in hospital were not excluded. Airedale NHS Foundation Trust Table 2: Records excluded from mortality analysis in this report The Royal Bournemouth and Christchurch Hospitals NHS Number secluded from 200912 survival analysis (number excluded from 2001/12 dataset) Reason 4370 (2019) No MRISii life status 708 (303) Time from discharge to follow-up either < 0 or > longest possible interval East Kent Hospitals University NHS Foundation Trust Medway NHS Foundation Trust* Papworth Hospital NHS Foundation Trust* Plymouth Hospitals NHS Trust* Royal United Hospital Bath NHS Trust South Warwickshire NHS Foundation Trust The Princess Alexandra Hospital NHS Trust* Foundation Trust Trafford Healthcare NHS Trust* University Hospitals of Leicester NHS Trust University Hospitals of Morecambe Bay NHS Foundation Trust* ii. The life status of all patients in the National Heart Failure Audit is provided by the Data Linkage Service of the NHS Information Centre (NHS IC). The audit data is linked to death registration data from the Office of National Statistics (ONS). iii. Hospital Episode Statistics (HES) and Patient Episode Database for Wales (PEDW) are the national statistical data warehouses for England and Wales respectively, recording details of all patient admissions to NHS hospitals. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 13 13 28/11/2012 14:19 Non-submitting Health Boards in Wales Cardiff & Vale University Health Board From April 2013 Trusts will be required to submit all of the patients discharged with a coded diagnosis of heart failure, and this number will be measured against the number of heart failure coded discharges recorded by HES in England and PEDW in Wales. Collecting data on all heart failure discharges will prevent any selection bias in the patient records submitted to the audit, and will thus ensure the representativeness of the National Heart Failure Audit. It will also significantly augment the research value of the dataset. 3.2.2 Number of patients Although Welsh case ascertainment has improved, it remains unsatisfactorily low. However as of April 2012 participation in the National Heart Failure Audit has been mandated by the Welsh Government, and as a result of this all Welsh Health Boards and the majority of hospitals have registered with the audit. 3.3 Demographics 3.3.1 Age The mean age of patients on their first admission in 2011/12 was 77.7, and on readmission 77.2; the median age was 80.1 on admission and 79.6 on readmission. 66.6% of patients were over 75 at their first admission, and 64.9% of readmitted patients were over 75. The total number of records submitted to the National Heart Failure Audit in 2011/12 was 41,635. After data cleaning and exclusion of invalid records (detailed above in section 3.1), the total number of records was 37,076. This was made up of 32,906 index admissions and 4,170 readmissions within the audit period. 3.3.2 Age and sex Of the index admissions, 24649 (74.9%) were recorded as having a confirmed diagnosis of heart failure, defined as a diagnosis of heart failure that has been confirmed by imaging or brain natriuretic peptide (BNP) measurement either during this admission or at a previous time. It is acknowledged that in some cases a clinician may justifiably diagnose heart failure in the absence of tests. Overall there were more men recorded in the audit than women, with men comprising 55.2% of the patient group at index admission and 58.2% at readmission. The mean age at first admission for men was 75.5 years, and 80.3 years for women. As in previous reports, the majority of patients up to the age of 85 were men (61.1%); in those over the age of 85 there were more women (57.9%). Fig 1: Age at first admission by sex 8000 3.2.3 Case ascertainment In England records were submitted on a total of 36,559 heart failure admissions, 61.9% of the 59,083 patients with heart failure recorded by HES in 2010/11; in Wales 517 records were submitted, 11.9% of the 4,348 total reported by PEDW in 2011/12. Overall this does not constitute a large increase compared to the number of patients recorded in the audit in 2010/11 (36,504 records, case ascertainment 54%). However if case ascertainment were judged against the 41,635 records counted prior to the data cleaning process, it would stand at 70.5% of all heart failure admissions. The lower-than-anticipated case ascertainment reflects the large number of 0 and 1 day admissions which were deleted as part of an extensive data cleaning process detailed in section 3.1 above. This has highlighted the need to remind participating hospitals not to include elective patients in the audit. 14 5836 6000 Number of patients The total number of cases where a patient was discharged with a primary diagnosis of heart failure recorded by HES and PEDW is 63,431, so the National Heart Failure audit currently represents 58.5% of all heart failure discharges in England and Wales. 6505 5304 4243 4051 4000 2127 2072 2000 862 433 0 219 18-44 862 371 45-54 55-64 65-74 75-84 85+ Age group Men Women 3.3.3 Age and Index of Multiple Deprivation As recorded in previous years, age at admission was related to Index of Multiple Deprivation. Index of Multiple Deprivation was assigned to each patient based on their postcode of residence. Indices of Multiple Deprivation are allocated to 34,378 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 14 28/11/2012 14:19 areas in England and Wales, each with an average of 1,500 and a minimum of 1,000 residents. There are seven factors considered: income deprivation; employment deprivation; health deprivation and disability; education, skills and training deprivation; barriers to housing and services; crime; and living environment deprivation. Mean age of admission for patients in the most deprived quintile, with a deprivation score of 5, was 74.5 years, compared with a mean age at admission of 79.6 years for patients in the least deprived quintile, with a deprivation score of 1 (figure 2). This is similar to the average age difference recorded last year (4.9 years). The National Heart Failure Audit intends to carry out further analysis on the variation in the treatment and management of heart failure in patients based on their Index of Multiple Deprivation. 3.4.2 Length of stay The overall mean length of stay was 13.1 days on index admission and 13.4 days on readmission, and the median length of stay was 9.0 days for both index admissions and readmissions. Mean length of stay was 12.7 days for those patients treated in a cardiology ward, 13.1 days for those treated in a general medical wards, and 14.7 days for patients in other wards. Median length of stay was 9 days for patients treated on cardiology wards, 8 days for patients treated on general medical wards, and 10 days for patients on other wards. Both mean and median length of stay varied significantly between hospitals, although the very high and very low mean figures may in many cases be explained by low numbers of Fig 3: Mean length of stay by hospital Fig 2: The effect of deprivation on age of first admission 80 79.6 79.1 78.3 78 76.9 77 76 75 74.5 Hospitals Mean age at first admission in audit period 2011/12 79 74 73 72 71 70 1 2 3 4 5 Index of multiple deprivation 0 5 10 15 20 25 Length of stay (mean) in days 1= least deprived 5= most deprived Fig 4: Median length of stay by hospital 3.4 Hospitalisation 47.6% of heart failure patients in the audit were treated in cardiology wards, with 41.3% being treated on general medical wards, and 10.8% on other wards. These findings do not show much change from 2010/11, when 45% of patients were treated on both cardiology wards and general medical wards, and the demographic characteristics of these patients also reflect last year’s findings. 54.1% of men were treated on cardiology wards, compared with only 39.5% of women. Women were more likely to be treated on general medical wards (47.9% vs. 36.0%) and other wards (12.4% vs. 9.5%). The likelihood of being treated on a cardiology ward decreased with age: 76.3% of patients who were 16-44 were treated on cardiology wards, compared with 47.1% of patients in the 7484 age group, and 32.1% of patients over 85. Hospitals 3.4.1 In-hospital care 0 5 10 15 Length of stay (median) in days National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 15 20 15 28/11/2012 14:19 patients submitted, with abnormally long or short admission spells (figure 3, figure 4). 3.4.3 Readmission Readmission data are incomplete since only readmission with a primary diagnosis of heart failure will be identified and not all cases even with a primary diagnosis have been recorded. The audit group is planning to identify readmissions from HES data in future years. This should provide robust data on readmission. There were 4,170 readmissions to hospital recorded in 2011/12. The analysis for this report defines an admission as the index admission within the audit period. There are some records of patients who were admitted to hospital with heart failure in 2011/12 who had been previously admitted in an earlier audit year. Such a record is treated as an admission for the purpose of this analysis, because it is the first admission for a patient within the audit period, although it is not the patient’s first admission to hospital with heart failure. 7,357 (19.8%) of the 37,076 records submitted to the National Heart Failure Audit in 2011/12 were readmissions, although only 4,170 (11.2%) were readmissions within the audit period. Most of these patients were only readmitted once, but some were readmitted two times or more (figure 5). The highest number of readmissions for a single patient was 10. Unsurprisingly, these symptoms were worse for readmissions to hospital, with 78% of readmitted patients in NYHA class III or IV, and 52% with moderate or severe oedema. 3.5.2 Aetiology The aetiology of heart failure reported by the audit is very similar to that reported in previous years. Hypertension (54%) and ischaemic heart disease (IHD) (46%) were the most common contributory causes of heart failure; 26% of patients had a history of both. 31% of patients in the audit had suffered a previous acute myocardial infarction (AMI), and 36% had a history of arrhythmia. Diabetes (31%) and valve disease (22%) were also very common. Patients with a history of IHD, atrial fibrillation, AMI and renal impairment were more likely to be diagnosed with LVSD, whereas patients with a history of valve disease or hypertension were more likely to be diagnosed with heart failure without LVSD (table 3). Table 3: Previous medical history and diagnosis of LVSD Medical History LVSD (%) Non-LVSD (%) Ischaemic Heart Disease 51 39 Atrial Fibrillation 41 30 2 readmissions Acute Myocardial Infarction 37 22 3 readmissions Valvular Heart Disease 19 28 Hypertension 52 58 Renal Impairment 26 17 Fig 5: Number of readmissions in 2011/12 81.2% to be in NYHA class IV, with breathlessness at rest. 29% of patients were admitted with moderate peripheral oedema, and 16% with severe peripheral oedema. 1 readmission 4+ readmissions p-value ≤0.001 in all cases 3.6 Diagnosis 3.6.1 Echocardiography 14.4% 3% 1.4% 3.5 Aetiology 3.5.1 Symptoms 40% of patients were in NYHA class III at first admission, with breathlessness on minimal activity, and 32% were deemed 16 86.0% of the patients recorded in the audit had an echocardiogram (echo) or other NICE-recommended imaging test, for example radionuclide imaging, computerised tomography (CT) scan or cardiac magnetic resonance imaging (MRI). Echocardiography rates continue to be commendably high, with 2011/12 findings representing an increase on the 82% recorded in 2010/11. However access to echocardiography was dependent on several factors: Patients were more likely to receive a diagnostic imaging test if they were men, with 88.8% of men having an echo compared to 82.6% of women. Patients National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 16 28/11/2012 14:19 aged less than 75 years were also more likely to have an echo (91.4% vs. 83.3%) as were those admitted to a cardiology ward (92.9% vs. 80.1% of those admitted to general medical wards, and 77.8% of patients admitted to other wards). 3.6.2 Diagnosis Of those patients who had an echo, 65.0% were diagnosed with LVSD. 13.8% of patients were diagnosed with valve disease following an echo, but only 3.8% were reported to have leftventricular hypertrophy (LVH) and 4.3% diastolic dysfunction. It is likely that low rates of LVH and diastolic dysfunction reflect under-reporting. Men were more likely to be diagnosed with LVSD, as were younger patients. 53.1% of patients over 75 were diagnosed with LVSD, compared with 70.7% of patients aged under 75 years. 67.6% of men and 48.3% of women had an echo diagnosis of LVSD, but women were more likely to be diagnosed with diastolic dysfunction (5.0% vs. 3.1%), LVH (4.0% vs. 3.0%) and valve disease (15.7% vs. 9.9%). 3.7 Treatment on discharge for LVSD All analyses on prescription rates for disease modifying treatments were performed on a denominator of those patients with a diagnosis of LVSD who survived to discharge. 3.7.1 ACE inhibitor and ARB 72% of patients were discharged on an angiotensin-converting enzyme (ACE) inhibitor, and 84% were discharged on either an ACE inhibitor or an angiotensin receptor blocker (ARB), or both. 1% were prescribed both an ACE inhibitor and an ARB. 87% of patients treated in a cardiology ward were discharged on an ACE inhibitor and/or an ARB, compared to 80% of those treated in a general medical ward and 76% of patients treated in other wards. Men were more likely to receive an ACE inhibitor and/or ARB than women, as were younger patients. Prescription rates of ACEI/ARB were 85% for men and 83% for women, and 89% of patients under 75 were discharged on either of the treatments, compared with 80% of patients over 75. 3.7.2 Beta blocker 78% of patients were prescribed a beta blocker on discharge. This is considerably higher than the 65% recorded in the 2010/11 audit, which was considered unsatisfactorily low. This is consistent with NICE guidance on prescription of beta blockers, which recommends that they are given to all patients with a diagnosis of LVSD, including older patients and patients with chronic obstructive pulmonary disease (COPD) without reversibility.25 discharged on a beta blocker. 83% of patients treated on a cardiology ward were given beta blockers, compared with 71% for both general medical patients and those on other wards. 79% of men were discharged on beta blockers, compared with 76% of women, and 84% of patients under 75 received the treatment versus 74% of those over 75. 3.7.3 MRA 45% of patients with LVSD were discharged on a mineralocorticoid receptor antagonist (MRA). Patients treated on cardiology wards were more likely to be prescribed an MRA (51%) compared with those on a general medical ward (37%) and patients on other wards (33%). Men were more likely to be discharged on an MRA than women (48% vs. 40%) as were patients under 75, compared with those over 75 (53% vs. 39%). 3.7.4 Loop diuretics 89% of patients in the audit were discharged on loop diuretics. 87% of patients on cardiology wards were prescribed a loop diuretic on discharge, slightly lower than the 93% of patients on general medical wards, and 90% of patients on other wards. Rates of prescription were similar in women and men (90% vs. 89%). Patients who were aged over 75 years on admission were more likely to be discharged on loop diuretics than younger patients (92% vs. 86%). 3.7.5 Thiazide diuretics 4% of patients were prescribed thiazide diuretics on discharge. Prescription rates were a little higher for those patients treated on a cardiology ward (5%) than for those treated on a general medical ward (3%) and on other wards (3%). Men were more likely to be prescribed thiazide diuretics than women (5% vs. 3%), as were patients over 75 compared with those under 75 (6% vs. 3%). 3.7.6 Digoxin 23% of patients were prescribed digoxin on discharge. Rates of prescription were similar in women and men (24% vs. 22%) and amongst patients aged above or below 75 years. Prescription rates were similar for patients on general medical (23%), cardiology (22%) and other wards (23%). 3.7.7 Treatment on discharge by age The prescription of ACE inhibitors, beta blockers and MRAs decreased with age. Only prescription of loop diuretics was higher amongst older patients (figure 6). As with ACEI/ARB prescription, patients treated in a cardiology ward, men, and younger patients were all more likely to be National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 17 17 28/11/2012 14:19 Fig 6: Treatment for LVSD on discharge by age 100 % of patients key heart failure drugs 90 80 70 60 50 40 30 76.5% of patients were referred onwards to their GP for followup, and 13.5% were referred to care of the elderly follow-up services. 20 10 0 51.7% of patients were referred to cardiology follow-up, that is, any follow-up involving a consultant cardiologist. As with heart failure liaison follow-up, cardiology patients were far more likely to be referred to cardiology follow-up, with 69.6% receiving onwards referral, compared with 34.4% of general medical patients and 31.7% of patients on other wards. Men were more likely to be referred to cardiology follow-up than women (57.6% vs. 44.2%), as were those under 75, of whom 67.2% received cardiology follow-up, compared to only 43.3% of patients over 75. 18-44 45-54 55-64 65-74 75-84 85+ Age group ACEI Loop diuretic Beta blocker MRA 3.8 Monitoring heart failure patients 3.8.1 Follow-up services 3.8.2 Palliative care Only 3.1% of patients were referred to palliative care services following the first admission, and 7.3% following a readmission. This does not constitute a significant improvement on 2010/11 data, which recorded referral levels of 4% on admission and 6% on readmission. These numbers are surprisingly low considering the age of the patient population, and the high mortality rates in the year following discharge. 53.7% of patients were referred to a heart failure liaison service, which is defined as a nurse led heart failure clinic. Patients treated in a cardiology ward were more likely to be referred to heart failure liaison services: 64.1% compared to only 43.3% for those on general medical wards and 42.9% for those on other wards. 59.0% of men and 47.1% of women were referred to nurse-led follow-up, and 60.8% of those under 75, compared with 49.9% of patients over 75. 18 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 18 28/11/2012 14:19 iv. HES data is from 2010/11, and PEDW data from 2011/12, due to availability. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 19 19 28/11/2012 14:19 8 903 Blackpool Teaching Hospitals NHS Foundation Trust Bolton NHS Foundation Trust 220 35 1.9% 243.4% 75.6% 9.7% 39.9% 155 Bedford Hospital NHS Trust Basildon and Thurrock University Hospitals NHS Foundation Trust Barts and the London 106.1% 72.6% 519 Barnet and Chase Farm Hospitals NHS Trust 113.1% 90.2% 0.0% 110.9% 61.9% % HES submitted 201 719 Barking, Havering and Redbridge University Hospitals NHS Trust Barnsley Hospital NHS Foundation Trust 296 0 296 36559 Trust records submitted Ashford and St Peter's Hospitals NHS Trust Airedale NHS Foundation Trust Aintree University Hospital NHS Foundation Trust England Trust name Table 4: Participation and case ascertainment in England Partial Yes Yes Partial Partial Yes Yes Yes Yes No Yes Participation status 423 371 291 362 388 277 489 636 328 245 267 59083 Primary HES heart failure discharges 327 363 229 339 478 256 391 492 305 242 221 52471 Secondary HES heart failure discharges 261 375 244 480 613 211 406 500 299 172 218 50315 Tertiary HES heart failure discharges King George Hospital Barnet General Hospital Chase Farm Hospital KGG BNT CHS BOL VIC BED BAS BAL Royal Bolton Hospital Blackpool Victoria Hospital Bedford Hospital Basildon University Hospital The London Chest Hospital/The Royal London Hospital Barnsley Hospital Queen's Hospital (Romford) OLD BAR St Peter's Hospital Airedale General Hospital University Hospital Aintree Hospital name SPH AIR FAZ NICOR hospital code 8 903 220 35 155 201 225 294 295 424 296 0 296 36559 Hospital records submitted Tables 4 and 5 compare the number of patient records submitted to the audit (after data cleaning) to the number of inpatients discharged with a primary diagnosis of heart failure, as recorded by HES for English Trusts and PEDW for Welsh Health Boards.iiivThe number of patients with a secondary and tertiary diagnosis of heart failure are also included. Participation is defined as a Trust or Health Board submitting either 20 cases per calendar month, or greater than 70% of their HES/PEDW recorded figures. 3.9.1 Participation and case ascertainment For the first time since it was established, the National Heart Failure Audit is publishing a series of analyses at a hospital level. All hospitals are included that submitted over 100 records or over 70% of their HES/PEDW figures. There is significant variation across hospitals, but this is to some extent down to hospitals including unrepresentative patient populations in the audit. 3.9 Analysis by hospital 20 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 20 28/11/2012 14:19 239 367 Burton Hospitals NHS Foundation Trust Calderdale and Huddersfield NHS Foundation Trust 223 341 Countess of Chester Hospital NHS Foundation Trust Croydon Health Services NHS Trust 381 Colchester Hospital University NHS Foundation Trust 325 245 City Hospitals Sunderland NHS Foundation Trust County Durham and Darlington NHS Foundation Trust 178 84 Chelsea and Westminster Hospital NHS Foundation Trust Chesterfield Royal Hospital NHS Foundation Trust 221 Central Manchester University Hospitals NHS Foundation Trust 22 220 Buckinghamshire Healthcare NHS Trust Cambridge University Hospitals NHS Foundation Trust 628 170 Trust records submitted Brighton and Sussex University Hospitals NHS Trust Bradford Teaching Hospitals NHS Foundation Trust Trust name 75.6% 58.9% 132.2% 86.8% 67.7% 63.1% 46.4% 71.1% 4.7% 71.7% 91.6% 94.0% 114.8% 32.3% % HES submitted Yes Yes Yes Yes Yes Partial Partial Yes Partial Yes Yes Yes Yes Partial Participation status 295 552 258 439 362 282 181 311 467 512 261 234 547 527 Primary HES heart failure discharges 232 529 215 362 436 269 107 327 362 444 234 205 513 429 Secondary HES heart failure discharges 205 558 208 310 475 257 112 436 304 452 166 161 447 403 Tertiary HES heart failure discharges Stoke Mandeville Hospital SMV Darlington Memorial Hospital DAR Croydon University Hospital University Hospital of North Durham DRY MAY Countess of Chester Hospital Colchester General Hospital Sunderland Royal Hospital Chesterfield Royal Hospital Chelsea and Westminster Hospital Manchester Royal Infirmary Addenbrooke's Hospital Huddersfield Royal Infirmary COC COL SUN CHE WES MRI ADD HUD Calderdale Royal Hospital Wycombe General Hospital AMG RHI Princess Royal Hospital (Haywards Heath) PRH Queen's Hospital (Burton) Royal Sussex County Hospital RSC BRT Bradford Royal Infirmary Hospital name BRD NICOR hospital code 223 145 180 341 381 245 178 84 221 22 182 185 239 0 220 222 406 170 Hospital records submitted National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 21 21 28/11/2012 14:19 481 167 East and North Hertfordshire NHS Trust East Cheshire NHS Trust 210 287 128 261 121 Epsom and St Helier University Hospitals NHS Trust Frimley Park Hospital NHS Foundation Trust Gateshead Health NHS Foundation Trust George Eliot Hospital NHS Trust Gloucestershire Hospitals NHS Foundation Trust 212 424 East Sussex Healthcare NHS Trust Great Western Hospitals NHS Foundation Trust 234 East Lancashire Hospitals NHS Trust 0 262 Ealing Hospital NHS Trust East Kent Hospitals University NHS Foundation Trust 176 197 Doncaster and Bassetlaw Hospitals NHS Foundation Trust Dorset County Hospital NHS Foundation Trust 196 73 Derby Hospitals NHS Foundation Trust Dartford and Gravesham NHS Trust 83.8% 23.9% 133.2% 56.6% 121.6% 57.9% 69.3% 47.4% 0.0% 64.0% 134.7% 118.0% 89.8% 37.4% 38.4% 23.7% Yes Partial Yes Partial Yes Partial Yes Partial No Partial Yes Yes Yes Partial Partial Partial 253 507 196 226 236 363 612 494 833 261 357 222 196 527 510 308 275 467 217 262 236 349 476 515 661 152 305 158 201 446 418 228 276 412 191 249 257 319 338 536 636 171 253 181 179 441 380 191 Bassetlaw Hospital BSL Cheltenham General Hospital CHG The Great Western Hospital Gloucestershire Royal Hospital GLO PMS George Eliot Hospital Queen Elizabeth Hospital (Gateshead) Frimley Park Hospital NUN QEG FRM Epsom Hospital St Helier Hospital SHC EPS Eastbourne District General Hospital Conquest Hospital CGH DGE Royal Blackburn Hospital William Harvey Hospital WHH BLA Queen Elizabeth The Queen Mother Hospital Kent and Canterbury Hospital KCC QEQ Macclesfield District General Hospital MAC Queen Elizabeth II Hospital Lister Hospital LIS QEW Ealing Hospital EAL Dorset County Hospital Doncaster Royal Infirmary DID WDH Royal Derby Hospital Darent Valley Hospital DER DVH 212 54 67 261 128 287 100 110 206 218 234 0 0 0 167 214 267 262 176 69 128 196 73 22 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 22 28/11/2012 14:19 309 94.5% Yes Yes 327 397 264 332 230 204 362 252 KTH KCH KGH JPH Kingston Hospital NHS Trust 61.7% 302 310 245 Yes 292 King's College Hospital NHS Foundation Trust 79.1% 329 239 Partial 118 Kettering General Hospital NHS Foundation Trust 34.7% 148 114 196 James Paget University Hospitals NHS Foundation Trust Yes IOW 88.3% 173 Isle of Wight NHS PCT 621 CCH 594 CHH Imperial College Healthcare NHS Trust 621 464 HOM HIN Kingston Hospital King's College Hospital Kettering General Hospital James Paget University Hospital St Mary's Hospital, Newport Charing Cross Hospital Hammersmith Hospital St Mary's Hospital Paddington Hull Royal Infirmary Castle Hill Hospital Homerton University Hospital Hinchingbrooke Hospital Wexham Park Hospital Good Hope Hospital GHS WEX Solihull Hospital SOL Birmingham Heartlands Hospital EBH Royal Hampshire County Hospital RHC Harrogate District Hospital Basingstoke and North Hampshire Hospital NHH HAR St Thomas' Hospital Hospital name STH NICOR hospital code HAM Yes 411 154 111 279 757 162 295 351 Tertiary HES heart failure discharges Imperial College Healthcare NHS Trust 79.1% 431 144 151 292 740 153 265 368 Secondary HES heart failure discharges STM 491 Yes 245 169 388 1122 215 333 406 Primary HES heart failure discharges Imperial College Healthcare NHS Trust 171.0% Yes Partial Partial Yes Partial Partial Partial Participation status HRI 737 Hull and East Yorkshire Hospitals NHS Trust 86.5% 22.5% 18.3% 32.8% 60.5% 38.4% 56.4% % HES submitted Hull and East Yorkshire Hospitals NHS Trust 212 Homerton University Hospital NHS Foundation Trust 38 368 Heart of England NHS Foundation Trust Hinchingbrooke Health Care NHS Trust 130 Harrogate and District NHS Foundation Trust 71 128 Hampshire Hospitals NHS Foundation Trust Heatherwood and Wexham Park Hospitals NHS Foundation Trust 229 Trust records submitted Guy's and St Thomas' NHS Foundation Trust Trust name 309 245 239 114 173 99 151 241 110 627 212 38 71 0 161 207 130 0 128 229 Hospital records submitted National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 23 23 28/11/2012 14:19 117 136 346 404 Lewisham Healthcare NHS Trust Liverpool Heart and Chest Hospital NHS Foundation Trust Luton and Dunstable Hospital NHS Foundation Trust Maidstone and Tunbridge Wells NHS Trust North Middlesex University Hospital NHS Trust 171 78 484 North Bristol NHS Trust North Cumbria University Hospitals NHS Trust 374 2 Norfolk and Norwich University Hospitals NHS Foundation Trust Newham University Hospital NHS Trust 154 Milton Keynes Hospital NHS Foundation Trust 74 Mid Staffordshire NHS Foundation Trust 420 136 Mid Essex Hospital Services NHS Trust Mid Yorkshire Hospitals NHS Trust 263 Mid Cheshire Hospitals NHS Foundation Trust 0 248 Leeds Teaching Hospitals NHS Trust Medway NHS Foundation Trust 566 Lancashire Teaching Hospitals NHS Foundation Trust 55.3% 22.3% 126.7% 51.4% 0.8% 75.9% 64.9% 25.2% 34.7% 126.4% 0.0% 90.2% 121.8% 64.5% 40.5% 30.4% 123.3% Partial Partial Yes Yes Partial Yes Yes Partial Partial Yes No Yes Yes Partial Partial Yes Yes 309 350 382 728 242 203 647 294 392 208 300 448 284 211 289 815 459 176 372 373 696 169 164 491 227 211 228 241 448 271 118 181 719 581 156 310 324 746 169 129 393 187 201 216 256 336 255 150 175 704 469 Southmead Hospital Cumberland Infirmary BSM CMI NMH North Middlesex University Hospital West Cumberland Hospital Frenchay Hospital FRY WCI Norfolk and Norwich University Hospital Newham University Hospital Milton Keynes General Hospital NOR NWG MKH Dewsbury and District Hospital Pinderfields Hospital PIN DEW Stafford Hospital Broomfield Hospital Leighton Hospital SDG BFH LGH Medway Maritime Hospital Tunbridge Wells Hospital KSX MDW Maidstone Hospital Luton and Dunstable Hospital Liverpool Heart and Chest Hospital University Hospital Lewisham Leeds General Infirmary Chorley and South Ribble Hospital Royal Preston Hospital MAI LDH BHL LEW LGI CHO RPH 171 32 46 205 279 374 2 154 119 301 74 136 263 0 178 226 346 136 117 248 232 334 24 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 24 28/11/2012 14:19 212 256 400 203 736 Northern Devon Healthcare NHS Trust Northern Lincolnshire and Goole Hospitals NHS Foundation Trust Northumbria Healthcare NHS Foundation Trust Nottingham University Hospitals NHS Trust Oxford Radcliffe Hospitals NHS Trust Poole Hospital NHS Foundation Trust 307 0 296 Peterborough and Stamford Hospitals NHS Foundation Trust Plymouth Hospitals NHS Trust 645 Pennine Acute Hospitals NHS Trust 0 217 Northampton General Hospital NHS Trust Papworth Hospital NHS Foundation Trust 383 Trust records submitted North Tees and Hartlepool NHS Foundation Trust Trust name 146.2% 0.0% 89.4% 88.5% 0.0% 102.5% 25.5% 60.6% 75.5% 74.9% 77.0% 140.3% % HES submitted Yes No Yes Yes No Yes Partial Yes Yes Yes Yes Yes Participation status 210 635 331 729 274 718 797 660 339 283 282 273 Primary HES heart failure discharges 237 525 280 929 282 615 722 530 278 231 290 329 Secondary HES heart failure discharges 198 498 251 881 227 534 719 503 311 219 227 316 Tertiary HES heart failure discharges Queen's Medical Centre Nottingham City Hospital John Radcliffe Hospital Horton General Hospital UHN CHN RAD HOR PGH PLY Poole General Hospital Derriford Hospital Peterborough City Hospital Rochdale Infirmary BHH PET North Manchester General Hospital NMG Royal Oldham Hospital Hexham General Hospital HEX OHM Wansbeck General Hospital ASH Fairfield General Hospital North Tyneside Hospital NTY BRY Scunthorpe General Hospital SCU Papworth Hospital Diana Princess of Wales Hospital GGH PAP North Devon District Hospital NDD Northampton General Hospital University Hospital of Hartlepool HGH NTH University Hospital of North Tees Hospital name NTG NICOR hospital code 307 0 296 53 183 204 205 0 112 624 44 159 56 125 219 95 161 212 217 149 234 Hospital records submitted National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 25 25 28/11/2012 14:19 449 234 155 225 223 330 144 Royal Berkshire NHS Foundation Trust Royal Brompton and Harefield NHS Foundation Trust Royal Cornwall Hospitals NHS Trust Royal Devon and Exeter NHS Foundation Trust Royal Free London NHS Trust Royal Liverpool and Broadgreen University Hospitals NHS Trust Royal Surrey County Hospital NHS Foundation Trust 345 Sandwell and West Birmingham Hospitals NHS Trust 85 Shrewsbury and Telford Hospitals NHS Trust 359 315 Sherwood Forest Hospitals NHS Foundation Trust South Devon Healthcare NHS Foundation Trust 452 Sheffield Teaching Hospitals NHS Foundation Trust 7 342 Salisbury NHS Foundation Trust Scarborough and North East Yorkshire NHS Trust 241 Salford Royal NHS Foundation Trust 0 227 Rotherham NHS Foundation Trust Royal United Hospital Bath NHS Trust 319 Portsmouth Hospitals NHS Trust 87.1% 19.5% 72.2% 51.3% 2.7% 48.8% 209.8% 94.1% 0.0% 81.8% 148.6% 84.8% 71.9% 32.2% 46.7% 111.4% 78.8% 59.5% Yes Partial Yes Yes Partial Yes Yes Yes No Yes Yes Yes Yes Partial Partial Yes Yes Yes 412 437 436 881 258 707 163 256 455 176 222 263 313 481 501 403 288 536 236 331 269 905 256 614 139 331 395 141 237 229 389 428 512 305 323 543 243 304 221 736 212 608 150 301 434 144 272 224 620 395 375 261 250 509 Harefield Hospital HH Royal Hallamshire Hospital King's Mill Hospital Newark Hospital Princess Royal Hospital (Telford) Royal Shrewsbury Hospital RHA KMH NHN TLF RSS Torbay Hospital Northern General Hospital NGS TOR Scarborough General Hospital SCA Sandwell General Hospital Birmingham City Hospital DUD SAN Salisbury District Hospital Salford Royal Royal United Hospital Bath Royal Surrey County Hospital Royal Liverpool University Hospital Royal Free Hospital Royal Devon & Exeter Hospital SAL SLF BAT RSU RLU RFH RDE Royal Cornwall Hospital Royal Brompton Hospital NHB RCH Royal Berkshire Hospital Rotherham Hospital Queen Alexandra Hospital BHR ROT QAP 359 37 48 13 302 10 442 7 155 190 342 241 0 144 330 223 225 155 24 210 449 227 319 26 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 26 28/11/2012 14:19 267 South Tyneside NHS Foundation Trust 555 203 229 226 175 302 178 300 180 197 203 170 Southend University Hospital NHS Foundation Trust Southport and Ormskirk Hospital NHS Trust St George's Healthcare NHS Trust St Helens and Knowsley Teaching Hospitals NHS Trust Stockport NHS Foundation Trust Surrey and Sussex Healthcare NHS Trust Tameside Hospital NHS Foundation Trust Taunton and Somerset NHS Foundation Trust The Dudley Group NHS Foundation Trust The Hillingdon Hospitals NHS Foundation Trust The Ipswich Hospital NHS Trust The Newcastle Upon Tyne Hospitals NHS Foundation Trust 0 209 South Tees Hospitals NHS Foundation Trust South Warwickshire NHS Foundation Trust 262 Trust records submitted South London Healthcare NHS Trust Trust name 24.1% 53.0% 86.8% 38.7% 87.2% 73.0% 90.7% 50.0% 68.5% 43.3% 74.6% 165.2% 0.0% 147.5% 43.1% 34.7% % HES submitted Partial Partial Yes Partial Yes Yes Yes Partial Partial Partial Yes Yes No Yes Partial Yes Participation status 704 383 227 465 344 244 333 350 330 529 272 336 126 181 485 756 Primary HES heart failure discharges 680 418 171 375 343 286 302 399 390 506 224 241 232 140 563 550 Secondary HES heart failure discharges 559 429 155 379 292 223 242 358 354 608 191 268 180 112 817 526 Tertiary HES heart failure discharges Queen Mary's Hospital (Sidcup) James Cook University Hospital Friarage Hospital QMH SCM FRH The Ipswich Hospital Freeman Hospital Royal Victoria Infirmary FRE RVN Hillingdon Hospital Russells Hall Hospital Musgrove Park Hospital Tameside General Hospital East Surrey Hospital Stepping Hill Hospital Whiston Hospital St George's Hospital Southport and Formby District General Hospital Southend Hospital Warwick Hospital IPS HIL RUS MPH TGA ESU SHH WHI GEO SOU SEH WAR South Tyneside District Hospital Princess Royal University Hospital (Bromley) BRO STD Queen Elizabeth Hospital (Woolwich) Hospital name GWH NICOR hospital code 0 170 203 197 180 300 178 302 175 226 229 203 555 0 267 0 209 1 24 237 Hospital records submitted National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 27 27 28/11/2012 14:19 181 137 The Royal Wolverhampton Hospitals NHS Trust The Whittington Hospital NHS Trust 209 304 142 292 384 University Hospital of North Staffordshire NHS Trust University Hospital of South Manchester NHS Foundation Trust University Hospital Southampton NHS Trust University Hospitals Birmingham NHS Foundation Trust University Hospitals Bristol NHS Foundation Trust 0 0 University Hospitals of Leicester NHS Trust University Hospitals of Morecambe Bay NHS Foundation Trust 309 335 University College London Hospitals NHS Foundation Trust University Hospitals Coventry and Warwickshire NHS Trust 253 United Lincolnshire Hospitals NHS Trust 0 0 The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust Trafford Healthcare NHS Trust 201 0 The Princess Alexandra Hospital NHS Trust The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust 360 The North West London Hospitals NHS Trust 0.0% 0.0% 60.7% 94.6% 44.0% 27.3% 88.6% 28.1% 129.3% 32.0% 0.0% 53.9% 41.0% 0.0% 66.3% 0.0% 77.9% No No Yes Yes Yes Partial Yes Partial Yes Yes No Partial Partial No Partial No Yes 449 1169 509 406 663 521 343 743 259 790 96 254 442 584 303 290 462 351 741 577 423 382 464 473 483 272 748 104 160 317 662 291 218 361 281 658 671 458 357 443 444 461 298 693 83 165 304 615 316 238 335 Lincoln County Hospital Grantham and District Hospital LIN GRA Hospital of St Cross Glenfield Hospital Leicester Royal Infirmary Furness General Hospital RUG GRL LER FGH Royal Lancaster Infirmary University Hospital Coventry WAL RLI Bristol Royal Infirmary Queen Elizabeth Hospital (Edgbaston) Southampton General Hospital Wythenshawe Hospital University Hospital of North Staffordshire BRI QEB SGH WYT STO University College Hospital Pilgrim Hospital PIL UCL Trafford General Hospital Whittington Hospital New Cross Hospital Royal Bournemouth General Hospital Queen Elizabeth Hospital (King's Lynn) Princess Alexandra Hospital Central Middlesex Hospital Northwick Park Hospital TRA WHT NCR BOU QKL PAH CMH NPH 0 0 0 0 28 281 384 292 142 304 209 335 46 101 106 0 137 181 0 201 0 14 346 28 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 28 28/11/2012 14:19 74.7% 101.0% 245 212 218 639 116 206 219 392 513 188 253 220 West Hertfordshire Hospitals NHS Trust West Middlesex University Hospital NHS Trust West Suffolk NHS Foundation Trust Western Sussex Hospitals NHS Trust Weston Area Health NHS Trust Whipps Cross University Hospital NHS Trust Wirral University Teaching Hospital NHS Foundation Trust Worcestershire Acute Hospitals NHS Trust Wrightington, Wigan and Leigh NHS Foundation Trust Wye Valley NHS Trust Yeovil District Hospital NHS Foundation Trust York Teaching Hospital NHS Foundation Trust 85.3% 128.4% 92.6% 181.3% 71.9% 44.2% 66.9% 59.2% 86.8% 84.5% 66.8% 145 Warrington and Halton Hospitals NHS Foundation Trust 72.4% % HES submitted 241 Trust records submitted Walsall Healthcare NHS Trust Trust name Yes Yes Yes Yes Yes Partial Partial Partial Yes Yes Yes Yes Partial Yes Participation status 258 197 203 283 545 496 308 196 736 258 210 328 217 333 Primary HES heart failure discharges 276 163 180 334 454 383 268 144 561 229 181 287 265 345 Secondary HES heart failure discharges 226 132 181 348 500 303 266 133 495 225 216 220 218 297 Tertiary HES heart failure discharges St Richard's Hospital STR YDH YEO HCH AEI York District Hospital Yeovil District Hospital County Hospital Hereford Royal Albert Edward Infirmary Worcestershire Royal Hospital Alexandra Hospital RED WRC Arrowe Park Hospital Whipps Cross University Hospital WIR WHC Weston General Hospital Worthing Hospital WRG WGH West Suffolk Hospital West Middlesex University Hospital Watford General Hospital Warrington Hospital Manor Hospital Hospital name WSH WMU WAT WDG WMH NICOR hospital code 220 253 188 513 165 227 219 206 116 276 363 218 212 245 145 241 Hospital records submitted National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 29 29 28/11/2012 14:19 Hywel Dda Health Board Cwm Taf Health Board 161 2 0 172 Betsi Cadwaladr University Health Board Cardiff & Vale University Health Board 175 7 517 Trust records submitted Aneurin Bevan Health Board Abertawe Bro Morgannwg University Health Board Wales Trust name 23.4% 0.4% 0.0% 18.5% 19.4% 0.9% 11.9% % PEDW submitted Table 5: Participation and case ascertainment in Wales Partial Partial No Partial Partial Partial Participation status 688 467 541 928 901 823 4348 Primary PEDW heart failure discharges 479 332 497 478 713 804 3303 Secondary PEDW heart failure discharges 417 236 432 719 647 929 3380 Tertiary PEDW heart failure discharges Ysbyty Gwynedd GWY University Hospital of Wales Prince Charles Hospital Royal Glamorgan Bronglais General Hospital Prince Philip Hospital West Wales General Withybush General Hospital UHW PCH RGH BRG PPH WWG WYB Llandough Hospital Glan Clwyd Hospital CLW LLD Caerphilly District Miners Hospital/Ysbyty Ystrad Fawr YYF Wrexham Maelor Hospital Nevill Hall Hospital NEV WRX Royal Gwent Hospital GWE Llandudno General Hospital Singleton Hospital SIN LLA Princess Of Wales Hospital Neath Port Talbot Hospital NGH POW Morriston Hospital Hospital name MOR NICOR hospital code 4 5 6 146 1 1 0 0 172 0 0 0 0 175 0 0 7 0 0 517 Hospital records submitted 30 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 30 SPH KGG OLD BNT CHS Ashford and St Peter's Hospitals NHS Trust Barking, Havering and Redbridge University Hospitals NHS Trust Barking, Havering and Redbridge University Hospitals NHS Trust Barnet and Chase Farm Hospitals NHS Trust Barnet and Chase Farm Hospitals NHS Trust BAR AIR Airedale NHS Foundation Trust Barnsley Hospital NHS Foundation Trust FAZ Aintree University Hospital NHS Foundation Trust Barnsley Hospital Chase Farm Hospital Barnet General Hospital Queen's Hospital (Romford) King George Hospital St Peter's Hospital Airedale General Hospital University Hospital Aintree 201 225 294 424 295 296 0 296 36559 Records submitted England Hospital name 37076 NICOR hospital code England and Wales Trust name • % referred to cardiology follow-up: all records where patient survived to discharge. • % referred to HF liaison service: all records where patient had LVSD and survived to discharge. • % beta blocker on discharge: all records where patient had LVSD and survived to discharge. • % ACEI/ARB on discharge: all records where patient had LVSD and survived to discharge. • % cardiology inpatient: all records. • % received echo: all records. Denominators for tables 6 and 7 as follows: Table 6: Clinical practice in England (2011/12) 84.1% 86.2% 91.8% 98.6% 98.6% 84.8% 98.3% 85.9% 85.9% % received echo 20.4% 37.8% 59.5% 19.6% 21.0% 49.3% 83.4% 47.0% 47.1% % cardiology inpatient 92.9% 81.5% 97.2% 79.0% 72.0% 59.0% 65.6% 82.7% 82.7% % ACEI/ARB on discharge 82.1% 80.6% 86.2% 78.3% 70.8% 56.4% 75.1% 76.3% 76.4% % beta blocker on discharge 24.6% 71.9% 63.4% 82.0% 73.1% 51.4% 97.7% 63.2% 63.2% % referred to HF liaison service 43.2% 58.3% 50.6% 55.5% 55.5% 50.6% 91.2% 51.5% 51.1% % referred to cardiology follow-up Please note that these outputs have not been risk adjusted, but the denominators used for each analysis have been chosen to ensure that the outcomes are as representative as possible. The audit Project Board has decided to refrain from publishing outcomes data (e.g. readmission and mortality rates) at a hospital level until a satisfactory risk adjustment model has been developed. However, since April 2012 the National Heart Failure Audit has included a series of new mandatory data items, which will enable a sophisticated risk adjustment of the data to account for known confounders. This will enable the audit to publish outcome data at a hospital level in the near future. Tables 6 and 7 show the percentages of cases at each hospital receiving key diagnostic tests, therapies and referral to follow-up services at hospitals in England and Wales. Hospitallevel data on clinical practice has only been published if a hospital submitted more than 100 records to the audit, or greater than 70% of their HES recorded figures. An asterisk (*) in a cell indicates that too few records were submitted for a percentage to be published. harge. 3.9.2 Clinical practice arge. 28/11/2012 14:19 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 31 31 28/11/2012 14:19 BAL BAS BED VIC BOL BRD PRH RSC SMV AMG BRT RHI HUD ADD MRI WES CHE SUN COL COC Barts and the London Basildon and Thurrock University Hospitals NHS Foundation Trust Bedford Hospital NHS Trust Blackpool Teaching Hospitals NHS Foundation Trust Bolton NHS Foundation Trust Bradford Teaching Hospitals NHS Foundation Trust Brighton and Sussex University Hospitals NHS Trust Brighton and Sussex University Hospitals NHS Trust Buckinghamshire Healthcare NHS Trust Buckinghamshire Healthcare NHS Trust Burton Hospitals NHS Foundation Trust Calderdale and Huddersfield NHS Foundation Trust Calderdale and Huddersfield NHS Foundation Trust Cambridge University Hospitals NHS Foundation Trust Central Manchester University Hospitals NHS Foundation Trust Chelsea and Westminster Hospital NHS Foundation Trust Chesterfield Royal Hospital NHS Foundation Trust City Hospitals Sunderland NHS Foundation Trust Colchester Hospital University NHS Foundation Trust Countess of Chester Hospital NHS Foundation Trust Countess of Chester Hospital Colchester General Hospital Sunderland Royal Hospital Chesterfield Royal Hospital Chelsea and Westminster Hospital Manchester Royal Infirmary Addenbrooke's Hospital Huddersfield Royal Infirmary Calderdale Royal Hospital Queen's Hospital (Burton) Wycombe General Hospital Stoke Mandeville Hospital Royal Sussex County Hospital Princess Royal Hospital (Haywards Heath) Bradford Royal Infirmary Royal Bolton Hospital Blackpool Victoria Hospital Bedford Hospital Basildon University Hospital The London Chest Hospital/The Royal London Hospital 341 381 245 178 84 221 22 182 185 239 220 0 406 222 170 8 903 220 35 155 99.1% 99.5% 85.7% 75.3% * 88.2% * 91.8% 94.1% 72.4% 97.7% 82.3% 68.0% 82.4% * 91.4% 90.0% * 89.7% 68.0% 50.5% 24.5% 44.9% * 47.0% * 50.5% 62.2% 43.9% 70.5% 50.0% 6.8% 46.5% * 60.3% 38.6% * 69.7% 95.7% 81.4% 81.8% 91.5% * 89.0% * 95.6% 93.0% 90.4% 90.9% 86.5% 89.4% 79.5% * 85.1% 64.3% * 78.8% 92.0% 80.0% 77.4% 86.4% * 90.6% * 73.2% 69.6% 92.2% 81.3% 74.5% 84.6% 70.5% * 83.8% 74.1% * 83.5% 90.6% 94.6% 31.3% 48.8% * 77.8% * 53.2% 58.2% 43.2% 62.7% 75.0% 34.2% 59.0% * 70.9% 29.1% * 86.4% 51.9% 39.5% 50.7% 28.6% * 72.9% * 42.7% 55.2% 51.5% 79.1% 55.4% 33.5% 63.2% * 21.8% 55.1% * 85.7% 32 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 32 28/11/2012 14:19 QEW MAC KCC QEQ WHH BLA CGH DGE EPS East and North Hertfordshire NHS Trust East Cheshire NHS Trust East Kent Hospitals University NHS Foundation Trust East Kent Hospitals University NHS Foundation Trust East Kent Hospitals University NHS Foundation Trust East Lancashire Hospitals NHS Trust East Sussex Healthcare NHS Trust East Sussex Healthcare NHS Trust Epsom and St Helier University Hospitals NHS Trust DID Doncaster and Bassetlaw Hospitals NHS Foundation Trust LIS BSL Doncaster and Bassetlaw Hospitals NHS Foundation Trust East and North Hertfordshire NHS Trust DER Derby Hospitals NHS Foundation Trust EAL DVH Dartford and Gravesham NHS Trust Ealing Hospital NHS Trust MAY Croydon Health Services NHS Trust WDH DRY County Durham and Darlington NHS Foundation Trust Dorset County Hospital NHS Foundation Trust DAR NICOR hospital code County Durham and Darlington NHS Foundation Trust Trust name Epsom Hospital Eastbourne District General Hospital Conquest Hospital Royal Blackburn Hospital William Harvey Hospital Queen Elizabeth The Queen Mother Hospital Kent and Canterbury Hospital Macclesfield District General Hospital Queen Elizabeth II Hospital Lister Hospital Ealing Hospital Dorset County Hospital Doncaster Royal Infirmary Bassetlaw Hospital Royal Derby Hospital Darent Valley Hospital Croydon University Hospital University Hospital of North Durham Darlington Memorial Hospital Hospital name 100 206 218 234 0 0 0 167 214 267 262 176 128 69 196 73 223 180 145 Records submitted 49.0% 89.3% 88.1% 76.1% 75.4% 84.6% 62.9% 93.9% 71.0% 85.9% * 89.80% * 79.8% 97.8% 93.1% % received echo 43.0% 56.3% 53.2% 61.5% 56.3% 16.4% 57.7% 37.0% 21.0% 17.3% * 51.03% * 30.5% 53.9% 47.6% % cardiology inpatient 80.0% 73.2% 64.0% 82.0% 89.7% 62.6% 87.0% 72.5% 68.9% 95.0% * 81.11% * 63.3% 69.4% 86.5% % ACEI/ARB on discharge 40.0% 62.6% 57.0% 85.7% 86.5% 66.1% 82.4% 90.8% 80.5% 75.6% * 67.78% * 67.2% 71.7% 73.7% % beta blocker on discharge 63.6% 70.3% 63.2% 89.5% 50.0% 25.2% 78.4% 11.5% 47.3% 52.2% * 98.94% * 31.8% 46.6% 50.8% % referred to HF liaison service 35.6% 53.6% 44.9% 75.9% 62.9% 30.1% 74.2% 82.0% 29.5% 53.6% * 76.74% * 33.9% 48.5% 42.0% % referred to cardiology follow-up National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 33 33 28/11/2012 14:19 GHS Heart of England NHS Foundation Trust HRI EBH Heart of England NHS Foundation Trust Hull and East Yorkshire Hospitals NHS Trust HAR Harrogate and District NHS Foundation Trust CHH RHC Hampshire Hospitals NHS Foundation Trust Hull and East Yorkshire Hospitals NHS Trust NHH Hampshire Hospitals NHS Foundation Trust HOM STH Guy's and St Thomas' NHS Foundation Trust Homerton University Hospital NHS Foundation Trust PMS Great Western Hospitals NHS Foundation Trust HIN GLO Gloucestershire Hospitals NHS Foundation Trust Hinchingbrooke Health Care NHS Trust CHG Gloucestershire Hospitals NHS Foundation Trust WEX NUN George Eliot Hospital NHS Trust Heatherwood and Wexham Park Hospitals NHS Foundation Trust QEG Gateshead Health NHS Foundation Trust SOL FRM Frimley Park Hospital NHS Foundation Trust Heart of England NHS Foundation Trust SHC Epsom and St Helier University Hospitals NHS Trust Hull Royal Infirmary Castle Hill Hospital Homerton University Hospital Hinchingbrooke Hospital Wexham Park Hospital Solihull Hospital Good Hope Hospital Birmingham Heartlands Hospital Harrogate District Hospital Royal Hampshire County Hospital Basingstoke and North Hampshire Hospital St Thomas' Hospital The Great Western Hospital Gloucestershire Royal Hospital Cheltenham General Hospital George Eliot Hospital Queen Elizabeth Hospital (Gateshead) Frimley Park Hospital St Helier Hospital 110 627 212 38 71 161 0 207 130 0 128 229 212 67 54 261 128 287 110 64.5% 89.0% 84.0% * * 97.5% 97.1% 81.5% 85.9% 98.7% 85.4% * * 87.4% 78.1% 87.5% 69.1% 0.9% 75.8% 50.0% * * 78.0% 50.0% 51.5% 69.5% 60.3% 55.9% * * 34.1% 30.8% 72.1% 40.9% 77.3% 86.8% 82.7% * * 88.2% 84.5% 90.0% 92.6% 82.2% 95.4% * * 77.3% 65.1% 84.8% 83.3% 68.2% 83.8% 89.6% * * 75.6% 66.1% 90.2% 63.0% 77.8% 84.8% * * 85.0% 55.5% 65.2% 81.8% 60.9% 66.8% 72.6% * * 82.1% 68.3% 66.7% 83.3% 92.3% 89.1% * * 0.0% 65.1% 84.8% 70.3% 39.0% 84.6% 60.5% * * 40.1% 55.6% 44.4% 19.5% 80.3% 70.1% * * 50.7% 46.8% 60.2% 37.8% 34 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 34 28/11/2012 14:19 LDH MAI KSX MDW LGH Maidstone and Tunbridge Wells NHS Trust Maidstone and Tunbridge Wells NHS Trust Medway NHS Foundation Trust Mid Cheshire Hospitals NHS Foundation Trust RPH Lancashire Teaching Hospitals NHS Foundation Trust Luton and Dunstable Hospital NHS Foundation Trust CHO Lancashire Teaching Hospitals NHS Foundation Trust BHL KTH Kingston Hospital NHS Trust Liverpool Heart and Chest Hospital NHS Foundation Trust KCH King's College Hospital NHS Foundation Trust LEW KGH Kettering General Hospital NHS Foundation Trust Lewisham Healthcare NHS Trust JPH James Paget University Hospitals NHS Foundation Trust LGI IOW Isle of Wight NHS PCT Leeds Teaching Hospitals NHS Trust St Mary's Hospital Paddington STM Imperial College Healthcare NHS Trust Leighton Hospital Medway Maritime Hospital Tunbridge Wells Hospital Maidstone Hospital Luton and Dunstable Hospital Liverpool Heart and Chest Hospital University Hospital Lewisham Leeds General Infirmary Royal Preston Hospital Chorley and South Ribble Hospital Kingston Hospital King's College Hospital Kettering General Hospital James Paget University Hospital St Mary's Hospital, Newport Hammersmith Hospital HAM Imperial College Healthcare NHS Trust Charing Cross Hospital Hospital name CCH NICOR hospital code Imperial College Healthcare NHS Trust Trust name 263 0 178 226 346 136 117 248 334 232 309 245 239 114 173 241 151 99 Records submitted 100.0% 82.0% 93.8% 90.5% 95.6% 99.1% 98.8% 98.8% 100.0% 60.2% 95.1% 87.0% 83.3% 73.4% 99.2% 85.4% 91.9% % received echo 82.9% 43.8% 64.4% 26.3% 97.8% 45.3% 94.4% 37.7% 50.4% 34.6% 44.0% 74.9% 40.4% 26.0% 26.1% 47.0% 43.4% % cardiology inpatient 90.4% 97.7% 90.9% 92.3% 72.9% 86.7% 81.5% 80.0% 97.1% 80.0% 89.0% 83.0% 89.6% 71.4% 88.2% 89.4% 100.0% % ACEI/ARB on discharge 89.2% 55.7% 78.0% 71.4% 79.8% 92.9% 82.6% 81.6% 84.7% 48.5% 85.6% 85.7% 82.2% 42.0% 81.0% 86.5% 64.0% % beta blocker on discharge 69.7% 80.9% 89.2% 69.0% 76.2% 88.6% 98.7% 98.8% 96.6% 0.0% 49.2% 93.3% 12.8% 93.5% 30.3% 48.2% 60.7% % referred to HF liaison service 46.5% 60.7% 74.7% 47.1% 99.1% 96.7% 88.6% 86.4% 78.4% 44.7% 36.2% 53.3% 27.1% 48.3% 53.9% 76.2% 35.8% % referred to cardiology follow-up National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 35 35 28/11/2012 14:19 HEX NTY Northumbria Healthcare NHS Foundation Trust Northumbria Healthcare NHS Foundation Trust NTG North Tees and Hartlepool NHS Foundation Trust SCU HGH North Tees and Hartlepool NHS Foundation Trust Northern Lincolnshire and Goole Hospitals NHS Foundation Trust NMH North Middlesex University Hospital NHS Trust GGH WCI North Cumbria University Hospitals NHS Trust Northern Lincolnshire and Goole Hospitals NHS Foundation Trust CMI North Cumbria University Hospitals NHS Trust NDD BSM North Bristol NHS Trust Northern Devon Healthcare NHS Trust FRY North Bristol NHS Trust NTH NOR Norfolk and Norwich University Hospitals NHS Foundation Trust Northampton General Hospital NHS Trust NWG PIN Mid Yorkshire Hospitals NHS Trust Newham University Hospital NHS Trust DEW Mid Yorkshire Hospitals NHS Trust MKH SDG Mid Staffordshire NHS Foundation Trust Milton Keynes Hospital NHS Foundation Trust BFH Mid Essex Hospital Services NHS Trust North Tyneside Hospital Hexham General Hospital Scunthorpe General Hospital Diana Princess of Wales Hospital North Devon District Hospital Northampton General Hospital University Hospital of North Tees University Hospital of Hartlepool North Middlesex University Hospital West Cumberland Hospital Cumberland Infirmary Southmead Hospital Frenchay Hospital Norfolk and Norwich University Hospital Newham University Hospital Milton Keynes General Hospital Pinderfields Hospital Dewsbury and District Hospital Stafford Hospital Broomfield Hospital 219 56 95 161 212 217 234 149 171 32 46 205 279 374 2 154 301 119 74 136 90.9% * * 22.4% 84.9% 86.6% 78.2% 96.0% 83.0% * * 94.6% 93.2% 80.5% * 76.6% 94.0% 79.8% * 99.3% 45.7% * * 31.7% 50.2% 49.3% 58.5% 64.4% 7.6% * * 55.1% 34.4% 100.0% * 48.7% 53.5% 31.1% * 30.1% 60.5% * * 78.3% 74.0% 100.0% 97.7% 100.0% 92.9% * * 58.5% 80.2% 84.0% * 76.0% 84.9% 90.4% * 97.0% 79.3% * * 69.6% 54.3% 98.7% 93.2% 98.0% 79.3% * * 71.8% 72.4% 79.0% * 68.0% 87.6% 77.1% * 95.9% 47.1% * * 0.0% 71.3% 99.0% 75.6% 63.6% 86.2% * * 13.7% 1.9% 33.2% * 75.9% 69.7% 92.7% * 78.0% 29.6% * * 43.5% 30.1% 29.0% 30.4% 32.8% 36.0% * * 45.6% 21.0% 68.5% * 46.2% 60.4% 61.3% * 63.8% 36 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 36 28/11/2012 14:19 BHH OHM PET PLY PGH QAP ROT BHR Pennine Acute Hospitals NHS Trust Pennine Acute Hospitals NHS Trust Peterborough and Stamford Hospitals NHS Foundation Trust Plymouth Hospitals NHS Trust Poole Hospital NHS Foundation Trust Portsmouth Hospitals NHS Trust Rotherham NHS Foundation Trust Royal Berkshire NHS Foundation Trust RDE NMG Pennine Acute Hospitals NHS Trust Royal Devon and Exeter NHS Foundation Trust BRY Pennine Acute Hospitals NHS Trust RCH PAP Papworth Hospital NHS Foundation Trust Royal Cornwall Hospitals NHS Trust RAD Oxford Radcliffe Hospitals NHS Trust NHB HOR Oxford Radcliffe Hospitals NHS Trust Royal Brompton and Harefield NHS Foundation Trust UHN Nottingham University Hospitals NHS Trust HH CHN Nottingham University Hospitals NHS Trust Royal Brompton and Harefield NHS Foundation Trust ASH NICOR hospital code Northumbria Healthcare NHS Foundation Trust Trust name Royal Devon & Exeter Hospital Royal Cornwall Hospital Royal Brompton Hospital Harefield Hospital Royal Berkshire Hospital Rotherham Hospital Queen Alexandra Hospital Poole General Hospital Derriford Hospital Peterborough City Hospital Royal Oldham Hospital Rochdale Infirmary North Manchester General Hospital Fairfield General Hospital Papworth Hospital John Radcliffe Hospital Horton General Hospital Queen's Medical Centre Nottingham City Hospital Wansbeck General Hospital Hospital name 225 155 210 24 449 227 319 307 0 296 204 53 183 205 0 624 112 159 44 125 Records submitted 77.78% 84.52% 100.00% * 88.2% 83.3% 96.6% 70.7% 87.5% 90.7% * 95.1% 80.0% 95.7% 96.4% 88.7% * 93.6% % received echo 52.89% 43.23% 98.50% * 46.1% 32.6% 94.0% 23.1% 71.6% 4.4% * 40.4% 63.4% 22.8% 17.9% 18.9% * 49.6% % cardiology inpatient 100.00% 81.08% 92.00% * 83.3% 80.4% 79.9% 70.5% 75.4% 87.8% * 83.0% 86.0% 99.6% 100.0% 75.8% * 81.1% % ACEI/ARB on discharge 100.00% 70.54% 87.84% * 83.4% 81.9% 74.8% 67.0% 65.7% 63.4% * 82.5% 80.4% 98.7% 97.1% 67.4% * 67.6% % beta blocker on discharge 75.00% 61.86% 52.27% * 72.9% 69.5% 77.9% 20.0% 51.7% 97.1% * 91.2% 93.9% 91.7% 93.0% 70.0% * 69.3% % referred to HF liaison service 40.21% 37.14% 97.52% * 28.2% 37.1% 43.7% 28.0% 59.6% 83.3% * 55.3% 31.9% 54.1% 17.3% 31.9% * 12.0% % referred to cardiology follow-up National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 37 37 28/11/2012 14:19 NHN TLF Sherwood Forest Hospitals NHS Foundation Trust Shrewsbury and Telford Hospitals NHS Trust FRH KMH Sherwood Forest Hospitals NHS Foundation Trust South Tees Hospitals NHS Foundation Trust RHA Sheffield Teaching Hospitals NHS Foundation Trust QMH NGS Sheffield Teaching Hospitals NHS Foundation Trust South London Healthcare NHS Trust SCA Scarborough and North East Yorkshire NHS Trust GWH SAN Sandwell and West Birmingham Hospitals NHS Trust South London Healthcare NHS Trust DUD Sandwell and West Birmingham Hospitals NHS Trust BRO SAL Salisbury NHS Foundation Trust South London Healthcare NHS Trust SLF Salford Royal NHS Foundation Trust TOR BAT Royal United Hospital Bath NHS Trust South Devon Healthcare NHS Foundation Trust RSU Royal Surrey County Hospital NHS Foundation Trust RSS RLU Royal Liverpool and Broadgreen University Hospitals NHS Trust Shrewsbury and Telford Hospitals NHS Trust RFH Royal Free London NHS Trust Friarage Hospital Queen Mary's Hospital (Sidcup) Queen Elizabeth Hospital (Woolwich) Princess Royal University Hospital (Bromley) Torbay Hospital Royal Shrewsbury Hospital Princess Royal Hospital (Telford) Newark Hospital King's Mill Hospital Royal Hallamshire Hospital Northern General Hospital Scarborough General Hospital Sandwell General Hospital Birmingham City Hospital Salisbury District Hospital Salford Royal Royal United Hospital Bath Royal Surrey County Hospital Royal Liverpool University Hospital Royal Free Hospital 0 1 237 24 359 37 48 13 302 10 442 7 155 190 342 241 0 144 330 223 * 92.4% * 63.0% * * * 78.1% * 100.0% * 94.2% 88.4% 95.0% 90.0% 72.9% 83.3% 93.27% * 61.2% * 31.8% * * * 49.3% * 26.9% * 69.0% 56.3% 61.7% 30.7% 26.4% 56.4% 45.29% * 89.2% * 60.0% * * * 79.8% * 78.6% * 88.6% 67.7% 87.2% 65.0% 86.7% 75.5% 97.47% * 93.8% * 47.0% * * * 81.4% * 72.3% * 62.4% 54.0% 76.1% 74.3% 65.2% 87.6% 95.18% * 82.9% * 20.2% * * * 65.0% * 0.0% * 98.9% 64.9% 31.3% 91.8% 8.9% 92.0% 64.55% * 63.6% * 33.1% * * * 51.5% * 29.0% * 84.3% 76.7% 46.8% 46.3% 38.9% 42.8% 58.51% 38 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 38 28/11/2012 14:19 SCM STD WAR SEH SOU GEO WHI SHH ESU TGA MPH RUS HIL IPS FRE RVN CMH NPH South Tyneside NHS Foundation Trust South Warwickshire NHS Foundation Trust Southend University Hospital NHS Foundation Trust Southport and Ormskirk Hospital NHS Trust St George's Healthcare NHS Trust St Helens and Knowsley Teaching Hospitals NHS Trust Stockport NHS Foundation Trust Surrey and Sussex Healthcare NHS Trust Tameside Hospital NHS Foundation Trust Taunton and Somerset NHS Foundation Trust The Dudley Group NHS Foundation Trust The Hillingdon Hospitals NHS Foundation Trust The Ipswich Hospital NHS Trust The Newcastle Upon Tyne Hospitals NHS Foundation Trust The Newcastle Upon Tyne Hospitals NHS Foundation Trust The North West London Hospitals NHS Trust The North West London Hospitals NHS Trust NICOR hospital code South Tees Hospitals NHS Foundation Trust Trust name Northwick Park Hospital Central Middlesex Hospital Royal Victoria Infirmary Freeman Hospital The Ipswich Hospital Hillingdon Hospital Russells Hall Hospital Musgrove Park Hospital Tameside General Hospital East Surrey Hospital Stepping Hill Hospital Whiston Hospital St George's Hospital Southport and Formby District General Hospital Southend Hospital Warwick Hospital South Tyneside District Hospital James Cook University Hospital Hospital name 346 14 0 170 203 197 180 300 178 302 175 226 229 203 555 0 267 209 Records submitted 96.5% * 58.2% 63.5% 91.9% 96.1% 80.3% 71.9% 76.2% 95.4% 92.5% 99.1% 96.1% 87.2% 91.8% 95.7% % received echo 84.7% * 68.8% 25.6% 52.8% 65.6% 52.7% 34.8% 54.4% 16.6% 77.0% 13.1% 18.3% 39.1% 64.0% 87.1% % cardiology inpatient 77.0% * 85.7% 86.8% 80.2% 77.8% 83.7% 80.8% 81.5% 92.7% 78.7% 87.3% 67.5% 70.8% 94.4% 90.1% % ACEI/ARB on discharge 71.9% * 72.3% 81.3% 60.2% 74.7% 73.1% 76.7% 63.7% 87.5% 72.1% 84.9% 42.7% 77.4% 80.3% 77.5% % beta blocker on discharge 72.4% * 52.8% 46.1% 70.5% 72.5% 0.0% 72.6% 57.7% 32.2% 95.6% 94.9% 70.9% 85.3% 93.8% 93.3% % referred to HF liaison service 47.7% * 93.1% 22.3% 29.0% 68.6% 37.2% 50.4% 52.5% 42.2% 34.6% 48.7% 70.8% 38.7% 73.7% 63.6% % referred to cardiology follow-up National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 39 39 28/11/2012 14:19 SGH University Hospital Southampton NHS Trust LER WYT University Hospital of South Manchester NHS Foundation Trust University Hospitals of Leicester NHS Trust STO University Hospital of North Staffordshire NHS Trust GRL UCL University College London Hospitals NHS Foundation Trust University Hospitals of Leicester NHS Trust PIL United Lincolnshire Hospitals NHS Trust WAL LIN United Lincolnshire Hospitals NHS Trust University Hospitals Coventry and Warwickshire NHS Trust GRA United Lincolnshire Hospitals NHS Trust RUG TRA Trafford Healthcare NHS Trust University Hospitals Coventry and Warwickshire NHS Trust WHT The Whittington Hospital NHS Trust BRI NCR The Royal Wolverhampton Hospitals NHS Trust University Hospitals Bristol NHS Foundation Trust BOU The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust QEB QKL The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust University Hospitals Birmingham NHS Foundation Trust PAH The Princess Alexandra Hospital NHS Trust Leicester Royal Infirmary Glenfield Hospital University Hospital Coventry Hospital of St Cross Bristol Royal Infirmary Queen Elizabeth Hospital (Edgbaston) Southampton General Hospital Wythenshawe Hospital University Hospital of North Staffordshire University College Hospital Pilgrim Hospital Lincoln County Hospital Grantham and District Hospital Trafford General Hospital Whittington Hospital New Cross Hospital Royal Bournemouth General Hospital Queen Elizabeth Hospital (King's Lynn) Princess Alexandra Hospital 0 0 281 28 384 292 142 304 209 335 106 101 46 0 137 181 0 201 0 95.0% * 93.8% 55.7% 100.0% 75.0% 81.6% 99.1% 59.4% 62.4% * 99.3% 75.1% 94.5% 74.6% * 89.3% 17.4% 39.4% 49.3% 31.1% 55.8% 27.4% 30.7% * 61.3% 11.6% 67.2% 86.1% * 80.8% 91.1% 0.0% 94.9% 71.9% 99.4% 73.7% 60.7% * 97.0% 78.5% 93.9% 76.3% * 78.7% 82.9% 0.0% 90.4% 56.1% 95.0% 76.3% 69.0% * 93.7% 67.2% 87.1% 94.2% * 64.4% 30.8% 0.0% 57.4% 82.9% 83.3% 28.2% 47.1% * 85.3% 65.1% 84.6% 51.7% * 80.4% 32.2% 49.2% 38.3% 60.1% 90.2% 50.0% 53.8% * 78.3% 30.7% 31.8% 40 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 40 28/11/2012 14:19 WAT WMU WSH STR WRG WGH WHC WIR RED WRC West Hertfordshire Hospitals NHS Trust West Middlesex University Hospital NHS Trust West Suffolk NHS Foundation Trust Western Sussex Hospitals NHS Trust Western Sussex Hospitals NHS Trust Weston Area Health NHS Trust Whipps Cross University Hospital NHS Trust Wirral University Teaching Hospital NHS Foundation Trust Worcestershire Acute Hospitals NHS Trust Worcestershire Acute Hospitals NHS Trust HCH YEO YDH Wye Valley NHS Trust Yeovil District Hospital NHS Foundation Trust York Teaching Hospital NHS Foundation Trust AEI WDG Warrington and Halton Hospitals NHS Foundation Trust Wrightington, Wigan and Leigh NHS Foundation Trust WMH RLI University Hospitals of Morecambe Bay NHS Foundation Trust Walsall Healthcare NHS Trust FGH NICOR hospital code University Hospitals of Morecambe Bay NHS Foundation Trust Trust name York District Hospital Yeovil District Hospital County Hospital Hereford Royal Albert Edward Infirmary Worcestershire Royal Hospital Alexandra Hospital Arrowe Park Hospital Whipps Cross University Hospital Weston General Hospital Worthing Hospital St Richard's Hospital West Suffolk Hospital West Middlesex University Hospital Watford General Hospital Warrington Hospital Manor Hospital Royal Lancaster Infirmary Furness General Hospital Hospital name 220 253 188 513 165 227 219 206 116 363 276 218 212 245 145 241 0 0 Records submitted 72.3% 92.1% 80.9% 97.3% 44.8% 87.7% 95.0% 83.0% 78.4% 75.5% 84.8% 69.3% 83.5% 94.7% 100.0% 100.0% % received echo 9.5% 55.6% 25.0% 62.0% 53.9% 35.9% 43.8% 33.0% 25.9% 40.5% 48.9% 33.0% 23.1% 50.6% 67.6% 52.3% % cardiology inpatient 84.0% 92.3% 77.4% 88.0% 83.0% 71.1% 98.7% 84.8% 69.8% 75.9% 76.8% 83.6% 71.8% 100.0% 94.1% 100.0% % ACEI/ARB on discharge 80.0% 85.3% 58.1% 87.7% 61.5% 79.8% 85.9% 77.3% 65.1% 72.4% 72.5% 68.0% 77.9% 99.1% 85.7% 100.0% % beta blocker on discharge 28.6% 100.0% 58.1% 68.2% 18.2% 42.2% 97.4% 75.0% 0.0% 59.0% 53.7% 12.8% 76.8% 81.6% 98.9% 90.4% % referred to HF liaison service 32.2% 40.5% 30.4% 66.0% 39.6% 53.3% 40.9% 47.4% 20.6% 47.1% 46.1% 34.2% 30.7% 92.1% 69.7% 78.0% % referred to cardiology follow-up HF Report 2012 Design B.indd 41 RGH BRG PPH WWG WYB Hywel Dda Health Board Hywel Dda Health Board Hywel Dda Health Board Hywel Dda Health Board WRX Betsi Cadwaladr University Health Board Cwm Taf Health Board LLA Betsi Cadwaladr University Health Board PCH CLW Betsi Cadwaladr University Health Board Cwm Taf Health Board GWE Aneurin Bevan Health Board UHW NEV Aneurin Bevan Health Board Cardiff & Vale University Health Board YYF Aneurin Bevan Health Board LLD SIN Abertawe Bro Morgannwg University Health Board Cardiff & Vale University Health Board POW Abertawe Bro Morgannwg University Health Board GWY NGH Abertawe Bro Morgannwg University Health Board Betsi Cadwaladr University Health Board MOR NICOR hospital code Abertawe Bro Morgannwg University Health Board Wales England and Wales Health Board name Singleton Hospital Princess of Wales Hospital Neath Port Talbot Hospital Morriston Hospital Hospital name Withybush General Hospital West Wales General Prince Philip Hospital Bronglais General Hospital Royal Glamorgan Prince Charles Hospital University Hospital of Wales Llandough Hospital Ysbyty Gwynedd Wrexham Maelor Hospital Llandudno General Hospital Glan Clwyd Hospital Royal Gwent Hospital Nevill Hall Hospital Caerphilly District Miners Hospital/Ysbyty Ystrad Fawr Table 7: Clinical practice in Wales (2011/12) National Heart Failure Audit April 2011-March 2012 41 28/11/2012 14:19 4 5 6 146 1 1 0 0 0 172 0 0 0 175 0 0 7 0 0 517 37076 Records submitted * * * 94.5% * * 79.1% 87.4% * 87.0% 85.9% % received echo * * * 82.2% * * 37.2% 39.4% * 52.9% 47.1% % cardiology inpatient * * * 88.2% * * 64.2% 92.3% * 81.6% 82.7% % ACEI/ARB on discharge * * * 70.2% * * 74.7% 92.9% * 79.3% 76.4% % beta blocker on discharge * * * 66.2% * * 78.9% 48.4% * 64.5% 63.2% % referred to HF liaison service * * * 34.2% * * 33.9% 19.5% * 29.2% 51.1% % referred to cardiology follow-up 3.10 Mortality Mortality in the National Heart Failure Audit database is determined by linking audit data with mortality data from the Office of National Statistics (ONS) via NHS number, and other patient identifiable data collected by the audit. The total number of patients in the audit database who could be assigned a mortality status by MRIS was 24,744. The followup period refers to the period from date of discharge to date of death for those patients who died, and date of discharge to date of census for those who survived. Currently the audit uses all-cause mortality as the basis for all mortality analysis, but NICOR has now been granted permission by the National Information Governance Board (NIGB) to obtain cause of death for patients included in its audits and registers.v This will allow for a more accurate representation of the number of deaths caused by heart failure, as an elderly patient group with high levels of comorbidity is guaranteed to register a significant number of non-cardiovascular deaths. 3.10.1 2011/12 in-hospital mortalityvi Overall 11.1% of patients died in hospital but in-hospital mortality rates varied depending on the ward on which the patient was treated: 7.8% of those on cardiology ward died in hospital, compared with 13.2% of patients treated on general medicine and 17.4% of those on other wards. In-hospital mortality stood at 10.2% for men and 12.1% for women, and, predictably, was much higher for older patients: only 2.5% of patients in the 16-44 age group died in hospital, compared with 10.9% of patients who were aged 75-84 at admission, and 16.8% of patients over 85 years of age. Following adjustment for confounding factors (age >75 years; NYHA class III/IV; previous AMI), a significant association remained between not being treated on a cardiology ward and worse survival outcomes (HR=1.66, 95% CI 1.52 to 1.81, p<0.001. 3.10.2 2011/12 post-discharge mortality Overall mortality for those patients who survived to discharge stood at 26.2% for the audit year. Median follow-up was 211 days for all patients, 281 days for those who survived to the end of the follow-up period and 39 days for patients who deceased (figure 7). Sex: Mortality rates were similar for men and women who survived to discharge, with 26.6% of women and 25.9% of men dying within the follow-up period (median follow-up of 231 days for both men and women) (figure 8). v. The NIGB monitors NHS and health-related information governance. vi. Data for the 2011/2012 mortality analysis can be found in appendix 3 at the end of this report. 42 Age: Predictably, mortality increased significantly with age, 7.4% of those aged 16-44 died (301 days median follow-up), compared with 26.9% of patients the 75-84 age group (229 days median follow-up) and 37.2% of those over 85 years (median follow-up of 200 days) (figure 9). Place of care: Patients treated on a cardiology ward had better outcomes than those treated on general medical or other wards, with 21.8% of patients treated on cardiology wards dying (242 day median follow-up), compared with 29.8% on general medicine (225 day median follow-up), and 33.4% on other wards (215 day median follow-up) (figure 10). Diagnosis of LVSD: Of patients without LVSD 28.3% died during the follow-up period, compared to 24.8% of those with LVSD (median follow-up time of 227 days for those without LVSD and 236 days for those with LVSD) (figure 11). ACE inhibitor and/or ARB on discharge: For those patients with an echo diagnosis of LVSD, 38.8% of those who were not discharged on an ACE inhibitor and/or ARB died, with a median follow-up of 201 days. Only 20.2% of patients with LVSD who were discharged on ACE inhibitor and/or ARB died within the follow-up period (median follow-up of 249 days) (figure 12). Mortality rates by ACEI/ARB prescription showed similar patterns when all patients were considered, rather than just those with a diagnosis of LVSD: 36.7% of patients who were discharged without ACE inhibitors and/or ARBs died, with a median follow-up period of 207 days, compared with 21.0% of patients discharged on the drugs (median follow-up of 247 days) (figure 13). Beta blocker on discharge: 33.0% of patients with LVSD who were not discharged on beta blockers died within the follow-up period (median 220 day follow-up), compared with only 21.1% of patients who were prescribed the treatment on discharge (median follow-up of 245 days) (figure 14). Irrespective of echo diagnosis, 32.1% of those discharged on no beta blocker died (227 median follow-up), compared with 22.2% of patients discharged on beta blockers (242 day median follow-up) (figure 15). Loop diuretic on discharge: 17.0% of patients with a diagnosis of LVSD who were discharged in 2011/12 without a prescription of loop diuretics died within the follow-up period, with a median 262 day follow-up, compared with 25.6% of patients who were discharged on loop diuretics (median follow-up period of 235 days) (figure 16). For all patients, including those without LVSD, 20.6% of patients discharged without loop diuretics died within the follow-up period (median 250 days), compared with 26.5% of patients discharged on a loop (231 day median follow-up) (figure 17). National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 42 28/11/2012 14:19 modifying drugs a patient was prescribed on discharge had a significant impact on survival: 45.8% of patients with LVSD discharged without a prescription for an ACEI/ARB, beta blocker or MRA died (median follow-up of 183 days), compared with 27.1% of those discharged on ACEI/ARB only (median follow-up 242 days) and 18.4% of patients discharged on an ACEI/ARB and a beta blocker (median follow-up 251 days). Mortality was 16.8% for patients discharged on ACEI/ARB, beta blocker and an MRA (257 days median follow-up) (figure 18). Referral to follow-up services: 20.1% of patients who were referred to cardiology follow-up in 2011/12 died (median follow-up 249 days), compared to 32.1% of patients who did not receive a cardiology referral (median follow-up of 216 days) (figure 19). Fig 7: Overall post-discharge survival 100 90 80 70 % survived Additive drug treatment: The number of recommended disease Table 8: Cox proportional hazards model for postdischarge mortality (2011/12) Predictor Hazard ratio Lower .95 Upper .95 p-value Previous AMI 1.28 1.20 1.36 < 0.001 Age > 75 1.77 1.65 1.90 < 0.001 NYHA class III/IV 1.22 1.13 1.31 < 0.001 No ACEI/ARB on discharge 1.69 1.59 1.81 < 0.001 No beta blocker on discharge 1.26 1.19 1.35 < 0.001 Loop diuretic on discharge 1.16 1.04 1.29 0.006 No cardiology follow-up 1.36 1.28 1.45 < 0.001 Not a cardiology inpatient 1.10 1.03 1.17 0.003 40 20 10 0 0 100 200 300 400 Days after discharge Fig 8: Post-discharge survival by sex 100 90 80 70 % survived A Cox proportional hazards model appears to show that for patients who survived to discharge, even with adjustment for age, severity of symptoms and history of AMI, those not prescribed ACE inhibitors/ARBs and beta blockers on discharge had higher mortality rates. Patients prescribed loop diuretics on discharge also had increased mortality rates following adjustment for these confounding factors. Patients who were not cardiology inpatients and those who did not receive cardiology follow-up also had increased mortality rates when the confounding patient characteristics were taken into account (table 8). 50 30 Mortality was 24.8% for patients who were referred to a heart failure liaison service on discharge (median follow-up 232 days), compared to 27.9% for patients not referred to heart failure nurse led follow-up (median follow-up period of 231 days) (figure 20). Predictors of mortality for survivors to discharge 60 60 50 40 30 20 10 0 0 100 200 300 400 Days after discharge Women Men National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 43 43 28/11/2012 14:19 Fig 9: Post-discharge survival by age at admission Fig 11: Post-discharge survival by presence or absence of LVSD 100 100 90 90 80 80 70 70 % Survived 60 % Survived 50 40 30 60 50 40 30 20 20 10 10 0 0 100 200 300 0 400 0 Days after discharge 100 200 300 400 Days after discharge 16-44 55-64 75-84 45-54 65-74 85+ Fig 10: Post-discharge survival by place of care Diagnosis of LVSD No diagnosis of LVSD Fig 12: Post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge for patients with LVSD 100 100 90 90 80 80 70 60 % Survived % Survived 70 50 40 30 50 40 30 20 20 10 10 0 0 100 200 300 Days after discharge Cardiology Other General Medicine 44 60 400 0 0 100 200 300 400 Days after discharge ACE inhibitor/ARB No ACE inhibitor/ARB National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 44 28/11/2012 14:19 Fig 13: Post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge (all patients) Fig 15: Post-discharge survival by prescription of beta blockers on discharge (all patients) 90 90 80 80 70 70 60 60 % Survived 100 % Survived 100 50 40 50 40 30 30 20 20 10 10 0 0 0 100 200 300 0 400 100 Days after discharge ACE inhibitor/ARB Beta blocker No ACE inhibitor/ARB No beta blocker 90 90 80 80 70 70 60 60 % Survived % Survived 100 50 40 50 40 30 30 20 20 10 10 0 0 200 300 400 0 100 Days after discharge Beta blocker No beta blocker 400 Fig 16: Post-discharge survival by prescription of loop diuretics on discharge for patients with LVSD 100 100 300 Days after discharge Fig 14: Post-discharge survival by prescription of beta blockers on discharge for patients with LVSD 0 200 200 300 400 Days after discharge No loop diuretic Loop diuretic National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 45 45 28/11/2012 14:19 Fig 19: Post-discharge survival by referral to cardiology follow-up services 100 100 90 90 80 80 70 70 60 60 % Survived % Survived Fig 17: Post-discharge survival by prescription of loop diuretics on discharge (all patients) 50 40 50 40 30 30 20 20 10 10 0 0 0 100 200 300 400 0 100 Days after discharge 300 400 Days after discharge No loop diuretic Referred to cardiology follow-up Loop diuretic Not referred to cardiology follow-up Fig 18: Post-discharge survival by additive drug treatment on discharge for patients with a diagnosis of LVSD Fig 20: Post-discharge survival by referral to heart failure liason follow-up services 100 100 90 90 80 80 70 70 60 % Survived % Survived 200 50 40 60 50 40 30 30 20 20 10 10 0 0 0 100 200 300 400 Days after discharge 0 100 200 300 400 Days after discharge ACEI inhibitor/ARB, beta blocker and MRA Referred to heart failure liaison follow-up ACEI inhibitor/ARB and beta blocker Not referred to heart failure liaison follow-up ACE inhibitor/ARB No ACEI inhibitor/ARB, beta blocker or MRA 46 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 46 28/11/2012 14:19 3.11 Three-year trends 3.11.1 Three-year in-hospital mortalityvii Over the three years from April 2009 to March 2012, 12.1% of patients died in hospital. Only 8.2% of patients treated on a cardiology ward died, compared with 14.7% of patient treated on general medical wards, and 18.5% of patients on other wards. 11.2% of men died in hospital, compared with 13.1% of women, in the three-year period. 3.11.2 Three-year post-discharge mortality Over the three years from 2009-2012, out of 66,249 patients, 24,590 (37.1%) died, with a median follow-up period between discharge and death/censoring of 331 days. Median followup was 504 days for patients who survived, and 89 days for patients who died (figure 21). The audit is not yet in a position to report place or cause of death for the majority of patients but hopes to do so in future reports. Sex: Long term mortality was broadly similar for men and women: 37.8% of women discharged alive within the three years died, with a 375 day follow-up period, compared to 36.6% of men (median follow-up 376 days) (figure 22). Age: Unsurprisingly age had a major impact on mortality, with 52.0% of patients over the age of 85 (median follow-up of 281 days) and 38.4% of patients between 75 and 84 (median followup of 369 days), dying within the follow-up period, compared with only 10.8% of the youngest patients, aged 16-44 (538 day median follow-up period) (figure 23). Place of care: Heart failure patients’ main place of care continued to have an impact on mortality long after discharge, with 31.1% of cardiology patients dying (404 day follow-up), compared with 42.4% of general medical patients (355 day follow-up) and 45.0% of patients on other wards (323 day follow-up) (figure 24). Diagnosis of LVSD: 40.7% of patients diagnosed with heart failure without LVSD admitted between 2009 and 2012 died, compared with 34.7% of patients diagnosed with LVSD (Median follow-up period of 362 days for no LVSD and 384 days for LVSD) (figure 25). ACE inhibitor and/or ARB on discharge: Of those patients discharged in 2009-12 diagnosed with LVSD, 50.1% of those who did not receive an ACE inhibitor or ARB on discharge died (median follow-up of 285 days), whereas only 30.2% of those who were prescribed an ACE inhibitor and/or ARB died (median follow-up of 417 days) (figure 26). 361 days for those discharged on no beta blocker and 403 days for patients discharged on a beta blocker) (figure 27). Loop diuretic on discharge: Of patients diagnosed with LVSD discharged between 2009 and 2012, 25.0% died within the follow-up period if they were not discharged on loop diuretics, compared with 35.8% of patients discharged on loop diuretics (follow-up 423 days for patients without loop diuretics, and 384 days for patients with loop diuretics) (figure 28). Additive drug treatment: Patients with a diagnosis of LVSD discharged on all three of ACEI/ARBs, beta blockers and MRAs had mortality rates of 25.0% over three years (median followup of 419 days). 26.9% of patients discharged on ACEI/ARBs and beta blockers in 2009-12 died (427 days median follow-up), compared with 40.6% for those discharged on an ACEI/ARB alone (412 days median follow-up). 56.7% of patients who left hospital on none of the three NICE recommended treatments in 2009-12 died (median follow-up of 257 days) (figure 29). Referral to follow-up services on discharge: Patients referred for cardiology follow-up had far better outcomes than those not referred for follow-up with a cardiologist, with mortality of 29.3% (422 days median follow-up) for the former, compared with 44.6% for the latter (327 days median follow-up) (figure 30). Those referred to heart failure liaison follow-up services had lower mortality (34.7%) than those not referred to nurse led follow-up (39.4%) across the three year audit period (median follow-up of 363 for those not referred to HF liaison service follow-up, and 384 days for patients referred to nurse led services on discharge) (figure 31). Three-year predictors of mortality for survivors to discharge Similar to the findings of the 2011/12 survival analyses, a Cox proportional hazards model shows that in 2009-12, even when accounting for age, severity of symptoms on admission and previous AMI, those patients who were not prescribed an ACE inhibitor/ARB and those not prescribed a beta blocker on discharge were more likely to die during the follow-up period than those given these therapies on discharge. The mortality rate also remained higher for patients discharged on a loop diuretic, those not referred to cardiology follow-up, and those who were not treated on a cardiology ward (table 9). Beta blocker on discharge: Of those patients discharged with a diagnosis of LVSD between 2009 and 2012, 45.9% of those not discharged on beta blockers died, compared with 29.4% of patients prescribed a beta blocker (median follow-up period of vii. Data for the 2009-12 mortality analysis can be found in appendix 4 at the end of this report. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 47 47 28/11/2012 14:19 Table 9: Cox proportional hazards model for postdischarge mortality (2009-12) Fig 22: Three-year post-discharge survival by sex (2009-12) Predictor Hazard ratio Lower .95 Upper .95 p value Previous AMI 1.26 1.22 1.31 < 0.001 Age > 75 1.82 1.75 1.89 < 0.001 NYHA class III/IV 1.15 1.11 1.19 < 0.001 No ACEI/ARB on discharge 1.58 1.52 1.63 < 0.001 No beta blocker on discharge 1.29 1.25 1.33 < 0.001 Loop diuretic on discharge 1.21 1.14 1.28 < 0.001 No cardiology follow-up 1.34 1.30 1.39 < 0.001 Not a cardiology inpatient 1.11 100 90 80 70 % Survived 60 50 40 30 20 1.08 1.15 < 0.001 10 0 0 Fig 21: Three-year post-discharge survival (2009-12) 200 400 600 800 1000 1200 Days after discharge 100 Women Men 90 80 Fig 23: Three-year post-discharge survival by age (2009-12) % Survived 70 60 100 50 90 40 80 30 70 % Survived 20 10 0 0 200 400 600 800 Days after discharge 1000 1200 60 50 40 30 20 10 0 0 200 400 600 800 1000 1200 Days after discharge 48 16-44 55-64 75-84 45-54 65-74 85+ National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 48 28/11/2012 14:19 Fig 24: Three-year post-discharge survival by place of care (2009-12) Fig 26: Three-year post-discharge survival by prescription of ACE inhibitor and/or ARB on discharge in patients with LVSD (2009-12) 100 100 90 90 80 80 % Survival post-discharge % Survived 70 60 50 40 30 20 10 70 60 50 40 30 20 10 0 0 200 400 600 800 1000 0 1200 0 200 400 600 Days after discharge 1000 1200 Days Other Cardiology 800 ACE inhibitor/ARB General Medicine No ACE inhibitor/ARB Fig 27: Three-year post-discharge survival by prescription of beta blockers on discharge in patients with LVSD (2009-12) Fig 25: Three-year post-discharge survival by presence or absence of LVSD (2009-12) 100 100 90 90 80 80 70 60 % Survived % Survived 70 50 40 30 60 50 40 30 20 20 10 10 0 0 200 400 600 800 Days after discharge 1000 1200 0 0 200 400 800 1000 1200 Days after discharge Diagnosis of LVSD No diagnosis of LVSD 600 Beta blocker No beta blocker National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 49 49 28/11/2012 14:19 Fig 28: Three-year post-discharge survival by prescription of loop diuretics on discharge in patients with LVSD (2009-12) Fig 30: Three-year post-discharge survival by referral to cardiology follow-up services (2009-12) 100 100 90 90 80 80 70 % Survived 70 % Survived 60 50 40 60 50 40 30 30 20 20 10 10 0 0 0 200 400 600 800 1000 0 1200 200 400 600 800 1000 1200 Days after discharge Days after discharge Beta blocker Referred to cardiology follow-up No beta blocker Not referred to cardiology follow-up Fig 29: Three-year post-discharge survival by additive drug treatment on discharge in patients with LVSD (2009-12) Fig 31: Three-year post-discharge survival by referral to heart failure liaison follow-up services (2009-12) 100 100 90 90 80 80 70 60 % Survived % Survived 70 60 50 40 50 40 30 30 20 20 10 10 0 0 0 0 200 400 600 800 1000 1200 200 400 600 800 1000 1200 Days after discharge Days after discharge ACEI inhibitor/ARB, beta blocker and MRA ACEI inhibitor/ARB and beta blocker Referred to heart failure liaison services Not referred to heart failure liaison services ACE inhibitor/ARB No ACEI inhibitor/ARB, beta blocker or MRA 50 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 50 28/11/2012 14:19 4 Case studies 4.1 Improving clinical practice and patient outcomes Lee Taaffe, North Central London Cardiovascular and Stroke Network In North Central London, data from the National Heart Failure Audit is used to measure and improve the heart failure services across the six hospitals in the North Central London Cardiovascular and Stroke Network. The North Central London Heart Failure Task Group, which is hosted by the Network, devised a suite of local measures covering activity, admissions, diagnostics, prescribing, length of stay, and mortality. The data from the National Heart Failure Audit, along with HES data, is analysed quarterly and presented at the Heart Failure Task Group for discussion and learning. At the end of the financial year an annual report is produced that details the outcomes for each hospital across the year and benchmarks performance against local and national report findings. Furthermore, the report benchmarks against previous years’ findings to show how each hospital is progressing in its delivery of services to patients. 4.2 Using data to drive improvement Pauline Wortman, Enhancing Quality & Recovery Enhancing Quality & Recovery (EQ&R) is an innovative and award winning clinician-led quality improvement programme across Kent, Surrey and Sussex. The programme works with teams in 10 Acute Trusts, six Community Providers and three Mental Health Trusts and spans 10 clinical pathways. Clinicians identify between four and seven evidence-based measures, aligned wherever possible to NICE guidance, in order to benchmark performance and drive forward quality improvement focussed on improving patient outcomes and reducing variation in care. Quality improvement that is clinically-led, data driven and focussed on patient outcomes is a very, very potent cocktail. EQ&R has recognised that when clinicians take ownership of their data and believe and trust it, this provides a very strong motivation to improve against it. Making this happen requires a clear focus on data quality: the need for a tightly defined population and clinical criteria so that ”apples are being compared with apples” and for a high level of data completeness (all patients, not just patients on the cardiology ward, for example). Improvement builds on clinicians “knowing where they are”, not just “where they think they are”. It also depends on clinical leadership and the development of wider teams, including coders and data analysts, for example, and truly collaborative working focussed on sharing of best practice and using the skills and knowledge of multi-disciplinary teams. At the core of the EQ&R approach is a focus on producing transparent measurement which is hard to ignore for accountability and improvement, rather than judgement. Collecting timely and relevant data on every patient, every time can appear to be a chore especially before the value of the information being produced is realised. EQ&R has found engagement needs to encompass all those involved in the audit loop with active sharing of results within teams. Action against the data is more likely if analysis is available as soon as is practicable. In this way quality data can be reflected upon and action taken harnessing and maintaining the momentum and enthusiasm for improvement in patient care. This immediacy and impetus for service improvement can be lost where data is not fed back in a timely and consistent way. Collaboration between EQ&R and MINAP and the National Heart Failure Audit is securing advantages for all parties. By sharing data, the duplication of data input is avoided. By capturing the full population rather than a sample population, data completeness is improved and the discipline of a monthly rather than yearly data deadline feeds into a faster service improvement cycle. Data collection and reporting provides the canvas on which to build service improvements, outcome improvements and variation reductions. The data collected within the EQ programme is specifically designed to monitor: • That every heart failure patient in hospital has appropriate Professor Sir Bruce Keogh, NHS Medical Director, EQ&R What a difference a year makes conference, Gatwick 25th January 2012. EQ&R is the inaugural winner of the Cardiac care category of the Health Service Journal & Nursing Times 2012 Integration Award. This achievement reflects the success of clinical teams across the region in introducing quality improvement metrics for the full heart failure pathway as well as collaborative working that has led to action to improve quality of patient care with reduced variation and improved patient outcomes across the region. diagnosis, management and appropriate information provided to them about their condition prior to discharge. • That every patient has a continuing plan. • That the ‘transfer of care’ between sectors contains minimum information. • Personalised care plans and patient held records meet ‘best practice’ standards and are completed with the patient within two weeks of discharge. • That medical management is optimised in the community. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 51 51 28/11/2012 14:19 • That end-of-life care is planned. Process • That there is a reduction in variations in clinical practice and outcomes. • That the patient experience is improved. Quality data provides the evidence that services are making improvements to reach the ultimate goal of delivering the care that each and every patient can expect: A quality of care delivered to every patient, every time, regardless of their local hospital or community provider, where they live, or who their GP is. 4.3 An example of local practice in conducting the National Heart Failure Audit Rachel Kindred, Denise Hockey and Lynne Thomas, Aneurin Bevan Health Board, South Wales Cases are identified monthly by the Information Department based on discharge codes Q&PS Improvement & Measurement Assistant obtains notes Heart Failure Specialist Nurse team analyses notes and completes audit pro forma Q&PS Improvement & Measurement Co-ordinator inputs data to the NICOR database, then exports data for analysis and feedback to Heart Failure clinical team meeting every two months. Challenges Left to right: Lynne Thomas (Quality and Patient Safety Improvement and Measurement Assistant), Denise Hockey (Heart Failure Nurse Specialist), Rachel Kindred (Quality and Patient Safety Improvement & Measurement Co-ordinator) Background Participation in the National Heart Failure Audit began at Nevill Hall Hospital in 2008 with a small patient group, namely those patients referred to the Heart Failure Specialist Nurse team. In 2009 the Clinical Audit Department (now the Quality & Patient Safety Improvement & Measurement Department), became involved with the data input, also using the data for the All Wales 1000 Lives Campaign. The patient group was widened in 2010 to include all those with a coded diagnosis of heart failure on discharge. In 2012 data collection began at Royal Gwent Hospital, the Health Board’s other main acute hospital. 52 The biggest challenge has been to achieve collaboration between the three departments (Information, Quality & Patient Safety and the Heart Failure Specialist Nurse team). This has involved regular communication to refine the identification of cases and the obtaining of case notes for the audit. Obtaining case notes has proved time consuming and requires close communication to ensure the notes are available at the right time to be viewed by a busy clinical team, before being removed when required by other departments of the hospital. Benefits The biggest benefit to participation has been the ability to export and review the data regularly as a team, allowing the comparison of data over time in order to resolve areas of lower compliance. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 52 28/11/2012 14:19 4.4 The national perspective Hugh F McIntyre, Chair NICE Heart Failure Quality Standard and Heart Failure Commissioning Outcome Framework/Quality Outcome Framework The central purpose of improving the quality of care is to reduce variation and improve outcome. Improving the quality of care requires defined standards and the systematic measurement of care against those standards. These measurements must then be made available to those accountable for delivering care to allow them both to benchmark and where necessary improve care. Based upon the heart failure guideline update (2010), measurable indicators of care - the heart failure quality standards - were published in 2011. These define the components of high quality care which services for patients with heart failure should seek to deliver and which commissioners will increasingly expect from any provider. Consistent delivery of improved standards of care should lead to better outcome. It is the role of the National Commissioning Board to deliver such improvement in outcomes - to do so will require a set of integrated indicators (currently under development) which will be delivered through the Commissioning Outcome Framework/Quality Outcome Framework process and will be used by the National Commissioning Board to hold Clinical Commissioning Groups to account. With standards established, the second component of quality improvement - consistent reliable local data - is fundamental to enable clinical teams to understand the quality of local care they deliver. Now in its sixth year, the National Heart Failure Audit, which covers nearly all of England and Wales, provides a dataset that not only addresses the majority of the hospitalbased quality standards but already indicates the potential link between better quality of care (for example place of care and optimal therapy) and better outcome. For the first time the introduction of hospital-level reporting provides specialist teams with measures of the inclusiveness and quality of the care which they deliver, and allows teams to compare their performance with that of local and national peers. Looking to the future, two areas are likely to become increasingly important. The National Commissioning Board sets five domains of outcome, which can be summarised as enhanced survival; quality of life; recovery (including both hospital admission and long term conditions); patient experience and safety. These move beyond the traditional ‘medical’ outcomes of death and readmission and are particularly relevant to heart failure - especially in older populations. Secondly the local mechanisms that deliver comparative data reporting (which are under development) will need to address not only the organised delivery of comparative data through networks, but also the mechanisms whereby local variations in quality of care can be targeted and reduced. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 53 53 28/11/2012 14:19 5 Research use of National Heart Failure Audit data Professor Henry Dargie, HALO Chair The National Heart Failure Audit is in its sixth year of activity, and is now collecting data on 60% of all patients discharged from hospital with heart failure in England and Wales. With over 130,000 records in the database, the audit has become a valuable research resource, and as the size and representativeness of the audit increases, so too will its significance for research projects. In 2011 HALO – the Heart failure Audit anaLysis and Outcomes group - was established to handle applications for the use of National Heart Failure Audit data from external groups, and to manage internal research projects. The National Heart Failure Audit has recently revised its dataset to include a series of new fields that will allow credible risk adjusted data to be produced. This data can be used for comparisons of outcomes among centres, and will allow the audit to start answering more sophisticated questions about variation in outcomes and to investigate the correlation between treatment and management, and outcomes for patients. We hope to start publishing risk adjusted data at a hospital level by 2013. Of particular interest to HALO is the prospect of investigating the very high mortality recorded by the audit, which is highly variable between centres. In 2011/12 overall mortality during admission stood at 11.1%, with much lower mortality in cardiology wards (7.8%) compared to General Medical wards (13.2%) and other wards (17.4%). The one-year mortality for those surviving to discharge was also very high (26.2%) and it is quite possible that recorded mortality rates will continue to rise as a result of increasing representativeness of the audit. Much higher than reported from Europe and the US, these high mortality rates probably reflect the relatively unselective nature of the data. The data seem to suggest that managing heart failure patients in a specialist setting has benefits beyond those conferred by higher prescription rates and optimal titration of evidence based drugs. This was shown dramatically for AMI when coronary care units (CCUs) were introduced by Desmond Julian in 1960s to provide early cardiopulmonary resuscitation (CPR), and mortality rates fell dramatically within a couple of years. Our hypothesis is that this was not due to CPR alone but to better management by cardiologists of the most common cause of death in CCUs which was then, and still remains, heart failure. However the extent to which the myriad factors affecting the outcomes for heart failure patients are managed better by specialists remains an unanswered and key research question, and one which HALO hopes to address. 54 Current HALO projects include a collaborative application for funding to the NIHR Health Technology Assessment (HTA) programme with Professor Barnaby Reeves of the University of Bristol and his team. The study has been commissioned by the HTA to determine the effect of BNP and NT-proBNP testing on outcomes for chronic heart failure patients, and to assess the cost-effectiveness of the technology. The HALO/University of Bristol application proposes to use audit data to supplement this systematic review, and to evaluate the efficacy of BNP testing in reducing mortality and readmission rates in heart failure patients. HALO is also involved in a collaborative project with Professor Kazem Rahimi from the George Centre for Healthcare Innovation at the University of Oxford, which will investigate the diverse factors affecting outcomes for heart failure patients. The project, funded by an NIHR grant, will look into various aspects of the delivery of heart failure care, in an attempt to determine the percentage of variation in outcomes that is determined by hospital related factors. This project ties in closely with the ambition of the National Heart Failure Audit to deliver risk adjusted data, and will be extremely valuable towards the goal of generating and publishing risk adjusted, hospital level analysis. Adam Timmis, Chair of MAG (MINAP academic group), has recently joined the group in order to develop a programme of research between MAG and HALO, looking at the incidence of heart failure and outcomes in post-infarction patients. This would involve linkage of MINAP and National Heart Failure Audit data, and tracking patients across multiple cardiovascular admissions to hospital. In addition to this, HALO is working with the European Society of Cardiology Heart Failure Association to produce an educational tool which incorporates the ESC guideline for the treatment and care of heart failure patients into the audit application. This will provide guidance on best practice and clinical standards alongside the data entry application, and will turn the audit database into a powerful tool for promoting and implementing optimal heart failure care. As HALO moves from strength to strength, we welcome applications for use of National Heart Failure Audit data from hospitals, universities and research groups. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 54 28/11/2012 14:19 6 Conclusions This audit confirms that patients admitted to hospital with a primary diagnosis of heart failure have a poor outcome despite contemporary pharmacological therapy, but that optimal treatment and management, which follows recommended clinical guidelines, is associated with improved outcomes. Patients are much more likely to receive this treatment if they are treated on a cardiology ward, and these patients consequently have lower mortality, both within hospital and following discharge. Improving the outcome of patients with heart failure requires four major approaches: • Improved case-ascertainment • Better treatments • Better implementation of existing treatment and management pathways • Better recognition and management of the end of life This cannot be achieved without better coordination and organisation of care across the spectrum of health and social care. Future audits will provide more detailed information on risk factors and devices. Increased access to other datasets will provide comprehensive data on the rate, duration and reasons for re-hospitalisation, and information on the cause of death will allow for more sophisticated mortality analyses. The audit group would like to thank all of the nurses, clinicians, clinical audit facilitators and all others involved in collecting and submitting data to the audit over the last five years. As the audit continues to grow it becomes more useful as a tool for monitoring the treatment and management of heart failure in England and Wales, both at a local and national level. The continued support and participation of hospitals, Trusts and Health Boards is essential for the success and development of the audit, and all of the work and input from individuals and hospitals across the U.K. is greatly appreciated. 6.1 Quality of care and patient outcomes The 2011/12 report supports the findings of previous years in emphasising the benefits of specialist cardiology input in the management of acute heart failure patients. The National Heart Failure Audit strongly supports the NICE guidance relating to heart failure, and continues to encourage its implementation. NICE has produced both a clinical guideline (2010) and a quality standard (2011) for chronic heart failure, which outline evidence based clinical guidance as to the most effective treatment and management of heart failure patients.26 On the basis of the findings in this report, the National Heart Failure Audit group recommends that Trusts and Health Boards ensure that patients with heart failure have specialist input to their care and are managed on cardiology wards wherever HF Report 2012 Design B.indd 55 feasible. Access to specialist medical and nursing care is essential to optimal care for heart failure patients, so Trusts should ensure that key personnel are in place to deliver this care. Key, evidence-based therapies should be initiated during a patient’s hospital admission. The use of ACE inhibitors/ARBs, beta blockers and MRAs for patients with left ventricular systolic dysfunction is associated with improved patient outcomes, and these treatments should be implemented wherever possible. Furthermore, audit findings suggest that robust arrangements for optimisation of therapy for cardiac dysfunction via cardiology follow-up, nurse-led heart failure liaison services and primary care need to be firmly in place prior to discharge. The next phase of the audit will address this discharge planning phase more specifically, but 2011/12 findings clearly show that referral to specialist follow-up services on discharge has beneficial effects on outcomes for heart failure patients. The audit showed in 2011/12 that outcomes for patients with heart failure without LVSD are poorer than for those with LVSD. This likely reflects the greater age of patients who do not have LVSD, but this aspect of heart failure care requires greater attention to identify other possible reasons for this difference and to determine improved management strategies. The continuing increase in case ascertainment coupled with data already accrued from previous audits will provide a robust basis for these aims and should be a focus of interest for subsequent audit reports. 6.2 Data completeness and participation The National Heart Failure Audit is a key tool for gathering information to improve outcomes in acute heart failure. Even though considerable progress has been made in case ascertainment since the audit began, the data is still not fully representative of the population of heart failure patients in England and Wales. The aim now should be to strive for inclusion of all patients admitted to hospital with a primary diagnosis of heart failure to ensure a more representative dataset. As of April 2013 hospitals will be required to submit data pertaining to all acute admissions with a primary discharge diagnosis of heart failure. By 2012/13, the audit aims to enrol 95% of eligible Trusts in England and Health Boards in Wales, and to capture 70% of all acute patients admitted to hospital with heart failure in England and Wales. Following the deletion of several thousand 0 and 1 day admissions from the 2011/12 data, which were believed to be elective admissions for patients with heart failure, hospitals are reminded that only acute heart failure patients should be included in the National Heart Failure Audit. The inclusion of elective admissions has the potential to skew survival analysis and misrepresent the treatment and management of heart failure in England and Wales. National Heart Failure Audit April 2011-March 2012 55 28/11/2012 14:19 7 Appendices Appendix 1: National Heart Failure Audit Project Board membership Name Representation Jackie Austin Nurse Consultant (Aneurin Bevan Health Board) and Lead Nurse (South Wales Cardiac Network) Gemma Baldock-Apps Cardiology Audit and Data Manager (East Sussex Healthcare NHS Trust) Lailaa Carr Contract and Project Officer (HQIP) John Cleland Professor of Cardiology (U. of Hull) Henry Dargie Professor of Cardiology and Consultant Cardiologist (U. of Glasgow); Chair of the Heart Failure Academic Group Nadeem Fazal National Clinical Audit Services Manager (NICOR) Jules Grange Heart Failure Specialist Nurse (East Sussex Healthcare NHS Trust) Suzanna Hardman Consultant Cardiologist (Whittington) and Chair of British Society for Heart Failure Candy Jeffries Interim Director (Beds and Herts Heart and Stroke Network) Helen Laing National Clinical Audit Lead (HQIP) Theresa McDonagh (Chair) National Heart Failure Audit Clinical Lead; Consultant Cardiologist and Professor of Heart Failure (KCH/KCL) Richard Mindham Heart failure patient representative Polly Mitchell National Heart Failure Audit Project Manager (NICOR) Marion Standing Developer (NICOR) Lynne Walker NICOR Programme Manager (NICOR) Appendix 2: HALO membership Name Representation John Cleland Professor of Cardiology (U. of Hull) Henry Dargie (Chair) Professor of Cardiology and Consultant Cardiologist (U. of Glasgow) Suzanna Hardman Consultant Cardiologist (Whittington) and Chair of BSH Theresa McDonagh National Heart Failure Audit Clinical Lead; Consultant Cardiologist and Professor of Heart Failure (KCL) Polly Mitchell National Heart Failure Audit Project Manager (NICOR) Appendix 3: Data for 2011/12 mortality analysis In-hospital mortality Analysis Variable Deaths Denominator Mortality (%) Overall In hospital deaths 3420 30886 11.1% Sex Men 1730 16969 10.2% Sex Women 1690 13910 12.1% Place of care Cardiology ward 1141 14635 7.8% Place of care General medical ward 1691 12833 13.2% Place of care Other ward 578 3316 17.4% Age 16-44 15 594 2.5% Age 45-54 29 1119 2.6% Age 55-64 136 2704 5.0% Age 65-74 416 5757 7.2% Age 75-84 1207 11102 10.9% Age ≥85 1617 9609 16.8% 56 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 56 28/11/2012 14:19 Mortality for survivors to discharge Analysis Variable Deaths Denominator Mortality (%) Overall All discharges 7182 27386 26.2% Sex Men 3937 15186 25.9% Sex Women 3244 12193 26.6% Place of care Cardiology ward 2944 13463 21.9% Place of care General medical ward 3308 11100 29.8% Place of care Other ward 914 2734 33.4% Age 16-44 43 576 7.5% Age 45-54 99 1086 9.1% Age 55-64 346 2561 13.5% Age 65-74 1068 5320 20.1% Age 75-84 2654 9864 26.9% Age ≥85 2972 7978 37.3% Diagnosis LVSD Dx LVSD 4087 16460 24.8% Diagnosis LVSD No Dx LVSD 3095 10926 28.3% ACEI/ARB on discharge (LVSD) ACEI/ARB 2527 12470 20.2% ACEI/ARB on discharge (LVSD) No ACEI/ARB 915 2361 38.8% ACEI/ARB on discharge (all) ACEI/ARB 3977 18895 21.0% ACEI/ARB on discharge (all) No ACEI/ARB 1995 5444 36.7% Beta blocker on discharge (LVSD) Beta blocker 2447 11592 21.1% Beta blocker on discharge (LVSD) No beta blocker 1079 3270 33.0% Beta blocker on discharge (all) Beta blocker 3806 17134 22.2% Beta blocker on discharge (all) No beta blocker 2350 7329 32.1% Loop diuretic on discharge (LVSD) Loop diuretic 3603 14075 25.6% Loop diuretic on discharge (LVSD) No loop diuretic 281 1658 17.0% Loop diuretic on discharge (all) Loop diuretic 6300 23798 26.5% Loop diuretic on discharge (all) No loop diuretic 521 2524 20.6% Additive drug treatment (LVSD) ACEI/ARB, beta blocker and MRA on discharge 734 4367 16.8% Additive drug treatment (LVSD) ACEI/ARB & beta blocker on discharge 809 4408 18.4% Additive drug treatment (LVSD) ACEI/ARB on discharge 357 1316 27.1% Additive drug treatment (LVSD) No ACEI/ARB, beta blocker or MRA on discharge 299 653 45.8% Referral to cardiology follow-up Cardiology follow-up 2745 13615 20.2% Referral to cardiology follow-up No cardiology follow-up 4082 12724 32.1% Referral to nurse-led follow-up HF liaison follow-up 3453 13922 24.8% Referral to nurse-led follow-up No HF liaison follow-up 3352 12000 27.9% National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 57 57 28/11/2012 14:19 Appendix 4: Data for 2009-12 mortality analysis Three-year in-hospital mortality (2009-12) Analysis Variable Deaths Denominator Mortality (%) Overall In hospital deaths 9082 75331 12.1% Sex Men 4605 41040 11.2% Sex Women 4472 34263 13.1% Place of care Cardiology ward 2872 34984 8.2% Place of care General medical ward 4742 32351 14.7% Place of care Other ward 1457 7888 18.5% Age 16-44 15 594 2.5% Age 45-54 29 1119 2.6% Age 55-64 136 2704 5.0% Age 65-74 416 5757 7.2% Age 75-84 1207 11102 10.9% Age ≥85 1617 9609 16.8% Three-year mortality for survivors to discharge (2009-12) Analysis Variable Deaths Denominator Mortality (%) Overall All discharges 24572 66167 37.1% Sex Men 13319 36380 36.6% Sex Women 11247 29764 37.8% Place of care Cardiology ward 9971 32074 31.1% Place of care General medical ward 11692 27572 42.4% Place of care Other ward 2889 6427 45.0% Age 16-44 159 1469 10.8% Age 45-54 384 2742 14.0% Age 55-64 1276 6247 20.4% Age 65-74 3868 13201 29.3% Age 75-84 9083 23652 38.4% Age ≥85 9799 18851 52.0% Diagnosis LVSD Diagnosis of LVSD 13534 39028 34.7% Diagnosis LVSD No Diagnosis of LVSD 11038 27139 40.7% ACEI/ARB on discharge (LVSD) ACEI/ARB on discharge (LVSD) 9124 30166 30.32 % ACEI/ARB on discharge (LVSD) No ACEI/ARB on discharge (LVSD) 2810 5604 50.1% Beta blocker on discharge (LVSD) Beta blocker on discharge (LVSD) 7658 26054 29.4% Beta blocker on discharge (LVSD) No beta blocker on discharge (LVSD) 4275 9317 45.9% Loop diuretic on discharge (LVSD) Loop diuretic on discharge (LVSD) 12002 33525 35.8% Loop diuretic on discharge (LVSD) No loop diuretic on discharge (LVSD) 1003 4005 25.0% 58 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 58 28/11/2012 14:19 Additive drug treatment (LVSD) ACEI/ARB, beta blocker and MRA on discharge 2389 9577 25.0% Additive drug treatment (LVSD) ACEI/ARB & beta blocker on discharge 2814 10470 26.9% Additive drug treatment (LVSD) ACEI/ARB on discharge 1606 3959 40.6% Additive drug treatment (LVSD) No ACEI/ARB, beta blocker or MRA on discharge 1013 1788 56.7% Referral to cardiology follow-up Cardiology follow-up 9581 32714 29.3% Referral to cardiology follow-up No cardiology follow-up 13652 30585 44.6% Referral to nurse-led follow-up HF liaison follow-up 11164 32175 34.7% Referral to nurse-led follow-up No HF liaison follow-up 11655 29575 39.4% Appendix 5: Glossary Term Acronym Acute Myocardial Infarction AMI Commonly known as a heart attack, a myocardial infarction results from the interruption of blood supply to part of the heart, which causes heart muscle cells to die. The damage to the heart muscle carries a risk of sudden death, but those who survive often go on to suffer from heart failure. Angiotensin II receptor antagonist/ angiotensin receptor blocker ARB A group of drugs usually prescribed for those patients who are intolerant of ACE inhibitors. Rather than lowering levels of angiotensin II, they instead prevent the chemical from having any effect on blood vessels. Angiotensinconverting enzyme inhibitor ACE inhibitor/ ACEI A group of drugs used primarily for the treatment of high blood pressure and heart failure. They stop the body’s ability to produce angiotensin II, a hormone which causes blood vessels to contract, thus dilating blood vessels and increasing the supply of blood and oxygen to the heart. Beta blocker A group of drugs which slow the heart rate, decrease cardiac output and lessen the force of heart muscle and blood vessel contractions. Used to treat abnormal or irregular heart rhythms, and abnormally fast heart rates. British Society for Heart Failure BSH The professional society for healthcare professionals involved in the care of heart failure patients. The BSH aims to improve care and outcomes for heart failure patients by increasing knowledge and promoting research about the diagnosis, causes and management of heart failure. Cardiac resynchronisation therapy CRT CRT, also known as biventricular pacing, aims to improve the heart’s pumping efficiency by making the chambers of the heart pump together. 25-50% of all heart failure patients have hearts whose walls do not contract simultaneously. CRT involves implanting a CRT pacemaker or ICD (implantable cardioverter-defibrillator) that has a lead positioned in each ventricle. Most devices also include a third lead which is positioned in the right atrium to ensure that the atria and ventricles contract together. Chronic obstructive pulmonary disease COPD The co-occurrence of chronic bronchitis and emphysema, a pair of commonly co-existing lung diseases in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs, causing shortness of breath (dyspnoea). In contrast to asthma, this limitation is poorly reversible and usually gets progressively worse over time. Contraindication A factor serving as a reason to withhold medical treatment, due to its unsuitability. Diuretic A group of drugs which help to remove extra fluid from the body by increasing the amount of water passed through the kidneys. Loop diuretic Echocardiography Echo A diagnostic test which uses ultrasound to create two-dimensional images of the heart. This allows clinicians to examine the size of the chambers of the heart and its pumping function in detail. Electrocardiography ECG A diagnostic test which interprets the electrical activity of the heart, detected by electrode attached to the arms, legs and chest. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 59 59 28/11/2012 14:19 Heart failure A syndrome characterised by the reduced ability of the heart to pump blood around the body, caused by structural or functional cardiac abnormalities. The condition is characterised by symptoms such as shortness of breath and fatigue, and signs such as fluid retention. Acute heart failure refers to the rapid onset of the symptoms and signs of heart failure, often resulting in a hospitalisation, whereas in chronic heart failure the symptoms develop more slowly. Hospital Episode Statistics HES The national statistical data warehouse for England of the care provided by NHS hospitals and for NHS hospital patients treated elsewhere. HES is the data source for a wide range of healthcare analysis for the NHS, government and many other organisations. The National Heart Failure Audit uses HES data to calculate case ascertainment. Left ventricular dysfunction LVD Any functional impairment of the left ventricle of the heart. Left ventricular ejection fraction LVEF A measurement of how much blood is pumped out of the left ventricle with each heartbeat. An ejection fraction of below 40% may be an indication of heart failure. Left ventricular systolic dysfunction LVSD A failure of the pumping function of the heart, characterized by a decreased ejection fraction and inadequate ventricular contraction. It is often caused by damage to the heart muscle, for example following a myocardial infarction (heart attack). Medical Research Information Service MRIS An NHS Information Centre service which links datasets at the level of individual patient records for medical research projects. NICOR uses MRIS to determine the life status of patients included in the audit, so as to calculate mortality rates. Mineralocorticoid receptor antagonist MRA A group of diuretic drugs, whose main action is to block the response to the hormone aldosterone, which promotes the retention of salt and the loss of potassium and magnesium. MRAs increase urination, reduce water and salt, and retain potassium. They help to lower blood pressure and increase the pumping ability of the heart. National Clinical Audit and Patient Outcomes Programme NCAPOP A group of 30 national clinical audits, funded by the Department of Health and overseen by HQIP that collect data on the implementation of evidence based clinical standard in U.K. Trusts, and report on patient outcomes. National Institute for Cardiovascular Outcomes Research NICOR Part of the National Centre for Cardiovascular Prevention and Outcomes, based in the Institute of Cardiovascular Science at University College London. NICOR manages six national clinical audits and three new technology registries. National Institute for Health and Clinical Excellence NICE A special health authority in England which provides guidance, sets quality standards and manages a national database to improve people’s health and prevent and treat ill health. NICE makes recommendations to the NHS on new and existing medicines, treatments and procedures, and on treating and caring for people with specific diseases and conditions. New York Heart Association class NYHA class NYHA classification is used to describe degrees of heart failure by placing patients in one of four categories based on how much they are limited during physical activity: Class I (Mild): No limitation of physical activity. Ordinary physical activity does not cause undue fatigue, palpitation, or dyspnoea (shortness of breath). Class II (Mild): Slight limitation of physical activity. Comfortable at rest, but ordinary physical activity results in fatigue, palpitation, or dyspnoea. Class III (Moderate): Marked limitation of physical activity. Comfortable at rest, but less than ordinary activity causes fatigue, palpitation, or dyspnoea. Class IV (Severe): Unable to carry out any physical activity without discomfort. Symptoms of cardiac insufficiency at rest. If any physical activity is undertaken, discomfort is increased. Oedema Patient Episode Database of Wales 60 An excess build-up of fluid in the body, causing tissue to become swollen. Heart failure patients often suffer from peripheral oedema, affecting the feet and ankles, and pulmonary oedema, in which fluid collects around the lungs. PEDW The national statistics database for Wales, collecting data on all inpatient and outpatient activity undertaken in NHS hospitals in Wales, and on Welsh patients treated in English NHS Trusts. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 60 28/11/2012 14:19 8 References 1. For example: EuroHeart Failure Survey II reports in- 6. National Institute for Health and Clinical Excellence (2010), hospital mortality rates of 6.7%, but has a patient group CG108 Chronic heart failure: Management of chronic heart of only 3580 (see Nieminen MS et al (2006), ‘EuroHeart failure in adults in primary and secondary care, http:// Failure Survey II (EHFS II): a survey on hospitalized acute publications.nice.org.uk/chronic-heart-failure-cg108. heart failure patients: description of population’, European Heart Journal 27(22):2725:36. http://www.ncbi.nlm.nih. 7. gov/pubmed/17000631), and the ESC Heart Failure Pilot Wislon P, Sutton G (2000), ‘Survival of patients with a new Survey recorded in-hospital mortality of only 3.8%, with a diagnosis of heart failure: a population based study’, Heart patient population of 5118 (1892 with acute heart failure) 83, 505–510. (see Maggioni AP et al, ‘EURObservational Research Programme: the Heart Failure Pilot Survey (ESC-HF Pilot)’, 8. heartfailure/additionalfiles. www.ncbi.nlm.nih.gov/pubmed/20805094). Also see the EuroHeart Failure survey programme. This showed 9.1% mortality for index hospitalisation in the U.K., compared to an average of 6.9%, but exhibited lots of evidence of biased reporting (Cleland JG, Swedberg K, Follath F, et al (2003), ‘The EuroHeart Failure survey programme- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis’, European Heart Journal 24 (5), 442-63, http://www.ncbi.nlm.nih.gov/ pubmed/12633546). National Institute for Health and Clinical Excellence (2011), QS9 Chronic heart failure quality standard, http:// publications.nice.org.uk/chronic-heart-failure-qualitystandard-qs9/list-of-statements. 3. National Institute for Health and Clinical Excellence (2010), CG108 Chronic heart failure: Management of chronic heart failure in adults in primary and secondary care, http:// publications.nice.org.uk/chronic-heart-failure-cg108. 4. Commission for Healthcare Audit and Inspection (2007), Pushing the boundaries: Improving services for people with heart failure, p.21, http://archive.cqc.org. uk/_db/_documents/Pushing_the_boundaries_ Improving_services_for_patients_with_heart_ failure_200707020413.pdf. 5. Scarborough P, Bhatnagar P, Wickramasinghe K, Smolina K, Mitchell C, Rayner M (2010), Coronary heart disease statistics: 2010 edition, British Heart Foundation Statistics Database, p.54, www.bhf.org. uk/idoc.ashx?docid=9ef69170-3edf-4fbb-a202a93955c1283d&version=-1. See National Heart Failure Audit annual reports from 2008/9, 2009/10 and 2010/11, www.ucl.ac.uk/nicor/audits/ European Journal of Heart Failure 12(10):1076-84. http:// 2. 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National Institute for Health and Clinical Excellence (2011), Chronic heart failure quality standard, http://www.nice. org.uk/guidance/qualitystandards/chronicheartfailure/ home.jsp. 14. Mcdonagh TA, Blue, L, Clark AL, Dahlström U, Ekman I, Lainscak M, McDonald K, Ryder M, Strömberg A, Jaarsma T (2011), ‘European Society of Cardiology Heart Failure Association Standards for Delivering Heart Failure Care’, European Journal of Heart Failure 13(3), 235-241, http:// eurjhf.oxfordjournals.org/content/13/3/235.full. National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 61 61 28/11/2012 14:19 15. The NHS Information Centre, Participation Rates in the 22. National Institute for Health and Clinical Excellence (2010), Heart Failure Audit (CV37), http://mqi.ic.nhs.uk/Search.as CG108 Chronic heart failure: Management of chronic heart px?query=heart%25failure&ref=1.05.27. failure in adults in primary and secondary care, http:// publications.nice.org.uk/chronic-heart-failure-cg108. 16. Care Quality Commission, Quality and Risk Profiles, http:// www.cqc.org.uk/organisations-we-regulate/registeredservices/quality-and-risk-profiles-qrps. 23. National Institute for Health and Clinical Excellence (2011), Chronic heart failure quality standard, http://www.nice. org.uk/guidance/qualitystandards/chronicheartfailure/ 17. Number 10, Letter to Cabinet Ministers on transparency and home.jsp. open data, http://www.number10.gov.uk/news/letter-tocabinet-ministers-on-transparency-and-open-data/. 18. Cleland JGF, Mcdonagh TA, Rigby AS, et al (2011), ‘The 24. See www.ucl.ac.uk/nicor/audits/heartfailure/dataset. 25. 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Department of Health, 2011/12 Standard terms and failure in adults in primary and secondary care, http:// conditions for acute hospital services (Gateway reference publications.nice.org.uk/chronic-heart-failure-cg108; 15458), http://www.dh.gov.uk/prod_consum_dh/groups/ National Institute for Health and Clinical Excellence (2011), dh_digitalassets/documents/digitalasset/dh_124518.pdf. Chronic heart failure quality standard, http://www.nice. 21. Welsh Government, NHS Wales National Clinical Audit and Outcomes Review Plan 2012/13, http://www.hqip.org.uk/ org.uk/guidance/qualitystandards/chronicheartfailure/ home.jsp assets/Core-Team/NHS-Wales-NCAOR-Plan-2012-13.pdf. 62 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 62 28/11/2012 14:19 National Heart Failure Audit April 2011-March 2012 HF Report 2012 Design B.indd 63 63 28/11/2012 14:19 This work remains the sole and exclusive property of UCL and may only be reproduced where there is explicit reference to the ownership of UCL. This work may be re-used by NHS and government organisations without permission. Commercial re-use of this work must be granted by UCL. Copyright © 2012 UCL, NICOR National Heart Failure Audit. All rights reserved. HF Report 2012 Design B.indd 64 28/11/2012 14:19