Matthew M. Clasen 4400 Massachusetts Avenue NW Washington, DC 20016 Phone: 202-885-1721 Email: mc0817a@student.american.edu Education The American University Doctoral Candidate (expected graduation date May, 2018) Master’s Thesis successfully defended on January 21st, 2016 Advisor: Dr. Anthony Riley PhD. Department: Psychology Program: Behavior, Cognition, & Neuroscience. Lab: Psychopharmacology GPA: 3.9 James Madison University Graduation: May 2014 Degree: B.S. in Psychology Minor: Biology GPA: 3.3 Northern Virginia Community College Graduated May 2011 Degree: Associate of Science Focus: Psychology GPA: 3.8 Relevant Course Work Introduction to Psychology Developmental Psychology Social Psychology Statistics for the Behavioral Sciences Sensation and Perception Psychology of Learning Applied Behavior Analysis Neurobiology Biopsychology Neuroscience of Sleep and Circadian Rhythms General Chemistry and Lab Biology of Organisms Evolution and Ecology Cell and Molecular Biology Advanced Psychological Statistics Genetics and Development Neural Circuits and Behavior Neural Bases of Learning and Memory Neuropharmacology Design of Experiments Biology of Addiction Special Lectures in Computational Neuroscience Nutritional Neuroscience Psychology of Drug Dependence Academic Awards Belle Haven Country Club: Bag Boy Scholarship Award Fall, 2010 Northern Virginia Community College: Award for Academic Excellence in Psychology Spring, 2011 James Madison University: Centennial Scholarship Program Fall, 2011 James Madison University: Outstanding Achievement in Research Award Spring, 2013 James Madison University: Dean’s Award for Best Research Poster Spring, 2013 James Madison University: 11th Annual Colonial Academic Alliance Undergrad Research Conference Award Spring, 2013 James Madison University: National Conference on Undergratuate Research Student Scholarship Award Fall, 2013 Research Grant Awards Travel Grants: Clasen, Matthew. “The Effect of Caffeine and REM Sleep Deprivation on Free Operant Responding”, Southeastern Association for Behavior Analysis. Columbia, SC. (2012) $300 received from James Madison University’s Department of Psychology. Clasen, Matthew. “Strategic Differences on a Radial Arm Maze Task in a Rodent Model of ADHD”, Association of Psychological Sciences. Washington D.C. (2013) $300 received from James Madison University’s Department of Psychology. Clasen, Matthew. “Effects of Brief Paradoxical Sleep Deprivation on Radial Arm Maze Performance in the SHR.”, Associated Professional Sleep Societies. Baltimore, MD. (2013) $300 received from James Madison University’s Department of Psychology. Clasen, Matthew. “The Effect of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat”, Colonial Academic Alliance Undergraduate Research Conference. Newark, DA. (2013) All expenses paid by James Madison University’s Office of Sponsored Events. Clasen, Matthew. “The Effect of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat.”, Society for Neuroscience. San Diego, CA. (2013) $300 received from James Madison University’s Department of Psychology. Clasen, Matthew. “The Effect of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat”, National Conference on Undergraduate Research. Lexington, KY. (2013) All expenses paid by James Madison University’s Office of Sponsored Events. Clasen, Matthew. “Adolescent Drug Pre-exposure Fails to Attenuate Taste Avoidance Conditioning”, Behavior, Biology, and Chemistry: Translational Research in Addiction. San Antonio, Texas. (2016) Selected to receive a stipend/travel prize that covers expenses for attendance and participation of the conference. Research Grants: Clasen, Matthew. $500 awarded from James Madison University’s Department of Psychology for the research project, “The Effect of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat.” (2013) Clasen, Matthew. $1008 awarded from James Madison University’s Department of Communication and Speech Disorders for the research project, “Auditory Masking in a Rodent Model of ADHD.” (2013) Clasen, Matthew. $1000 awarded from the Mellon Foundation at American University for the research project, “The assessment of methylphenidate upon conditioned taste avoidances within adolescence.” (2014) Clasen, Matthew. $695.30 awarded from the Mellon Foundation at American University for the research project, “In vivo manipulation of parabrachial neurons on the aversive effects of cocaine.” (2015) Conference Presentations Bradley, C., Peterson, D., McVay, S., Corbett, T., Henry, E., Sequeira, S., Clasen, M., Crosby, T., & Dyche, J. The Effects of Caffeine and REM Sleep Deprivation on Free Operant Responding Under a VI30 s Schedule of Reinforcement. Southeastern Association for Behavior Analysis, 2012. Clasen, M., Sequeira, S., McVay, S., Cooke, C., Houhoulis, S., Jeter, A., Keegan, R., Shemery, A., Williams, D.,Yohn, C., & Holt, D. The Effects of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat. Virginia Association for Behavior Analysis, 2013. McVay, S., Clasen, M., Sequeira, S., Cooke, C., Houhoulis, S., Jeter, A., Keegan, R., Shemery, A., Williams, D., Yohn,, C. Dyche, J., & Holt, D. Effects of Brief Paradoxical Sleep Deprivation on Radial Arm Maze Performance. Virginia Association for Behavior Analysis, 2013. Clasen, M., Sequeira, S., McVay, S., Cooke, C., Houhoulis, S., Jeter, A., Keegan, Shemery, A., Williams, D., Yohn C., & Holt, D. The Effects of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat. Colonial Academic Alliance Undergraduate Research Conference, 2013. Clasen, M., Sequeira, S., McVay, S., O’Malley, J. Shemery, A., Dyche, J., & Holt, D. The Effects of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat. Society for Neuroscience, 2013. Clasen, M., Sequeira, S., Franssen, C., Dyche, J., & Holt, D. The Effects of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat. National Conference on Undergraduate Research, 2014. Clasen, M., Sequeira, S., Franssen, C., Dyche, J., & Holt, D. The Effects of Cocaine on Delay Discounting in the Spontaneously Hypertensive Rat. NIDA/NIAAA and APA Divisions 28/50 Early Career Investigator Poster Session, 2014. Franssen, RA, Hauver, AJ, LaFerve, J, Clasen, M, Gaffney, K, Pardes, A, Pruett, R, Uyguner, H, Vassallo, M, Franssen, CL. Maternal rats use the frontal cortex to discriminate between OWN and ALIEN pups. Society for Neuroscience, 2014. Hauver, AJ, LeFerve, J, Mills, J, Russel, C, Clasen, M, Gaffney, K, Pardes, A, Pruett, R, Uyguner, H, Vassallo, M, Franssen, CL, Franssen, RA. Discrimination between Own and Alien Pups in the Maternal Rat. SYNAPSE, 2014. Amarante, L., Caetano, M., Clasen, M., Swanson, K.., Wetzell, B., & Laubach, M. Frontal cortical circuits for the control of consummatory behavior. Society for Neuroscience, 2015. Clasen, M., Wetzell, B., & Riley, A. Adolescent drug pre-exposure fails to attenuate taste avoidance conditioning. Behavior, Biology, and Chemistry: Translational Research in Addiction, 2016. Articles Garrett, B., Wakeford, A., Clasen, M., Friar, M., & Riley, A. The effects of Δ9-tetrahydrocannabinol (THC) drug history on THC taste and place conditioning. Pharmacology, Biochemistry, and Behavior. (IN PRESS) Clasen, M., Wetzell, B., & Riley, A. Adolescent male rats display attenuated taste avoidance learning relative to adults and fail to demonstrate a US pre-exposure effect. Learning and Behavior. (IN PRESS) Book Chapters Riley, A., Clasen, M., & Friar, M. Conditioned taste avoidance drug discrimination procedure: assessments and applications. Special Series in Behavioral Neuroscience, Springer. (Accepted for print) Teaching Assistantships and Experience Psychology of Learning (PSY 390): Dr. Daniel Holt (Spring 2013) Tutored students Lead test review sessions Graded exams and assignments with Dr. Holt Biopsychology (PSY 385): Dr. Catherine Franssen (Fall 2013) Tutored students Lead test review sessions Graded exams and assignments with Dr. Franssen Managed Canvas History and Systems of Psychology (PSYC 502): Dr. Maria Gomez (Fall 2014) Graded exams and essays Phsiological Psychology (PSYC 501): Dr. Maria Gomez (Fall 2014) Graded exams and essays Psychology as a Natural Science (PSYC 115): Dr. Maria Gomez (Spring 2015) Gave 3 guest lectures Drugs and Behavior (PSYC 240): Dr. Anthony L. Riley (Spring 2015 & Fall 2015) Graded assignments and essays Tutored students Managed all of Blackboard content Psychology as a Natural Science (PSYC 115): Dr. Anthony L. Riley (Spring 2016) Tutored students Grade assignments and exam Managed entire Cengage BrainTap course online LABORTORY EXPERIENCE (self-proficient in the following areas) Behavioral Assessments: Delay Discounting 8-Arm Radial Arm Maze Conditioned Taste Avoidance Conditioned Place Preference Intravenous Self-Administration Pharmacological Skills: Dose calculations Drug and solution mixing Intraperitoneal and sub-cutaneous injections Experience maintaining a schedule 2 drug log. Surgical Skills: Jugular catheter implantation surgery for self-administration (survival surgery; rat) General stereotaxic surgery (survival surgery; rat) Stereotaxic surgery for implantation of light sensitive opsin containing AAV’s and ferrule for optogenetics (survival surgery; rat) Implantation of DREADDs AAV (survival surgery; rat) Tissue Collection: Cardiac perfusion (rat) Rapid brain extraction (rat) Rapid brain dissection (rat) Tail vein blood collection (rat) Tissue Processing: Sledge microtome sectioning of the rat brain Frozen cryostat sectioning of the rat brain Micro-punch brain dissection of the rat brain using a frozen cryostat Cellular and Molecular Methods in Neuroscience Western Blot Analysis (rat brain) Blood brain barrier analysis using sodium fluorescein (rat brain) Immediate early gene expression (c-fos & Npas4; rat brain) Implantation of various adeno-associated viruses (AAV’s) into the rat brain (DREADDs, optogenetic probes, CRE dependent AAV’s, & non-CRE dependent AAV’s) Microscopy: Light microscopy Fluorescent microscopy Software and Hardware Skills Experience constructing and repairing Med PC operant boxes Experience running Med PC software MED-PC software programing Microsoft Office: Word, Excel, PowerPoint SPSS (Statistical Package for the Social Sciences) FIJI Adobe Photoshop Python toolbox Research Invitations Long Wood University: June 2013 Invited to work in Dr. Adam Franssen’s Research lab Practiced rat profusions and extractions Practiced cryostat techniques for well and dry slide mounting Studied and performed Immunohistochemistry Boston University: July 2013 Invited to work in Dr. Kathleen Kantak’s Research lab Studied and performed cocaine self-administration surgeries and techniques Experience surgically implanting femoral catheters Experience with rat post-surgical care May 30th- 31st June 27th –July 11th American University: Summer 2015 June 10th –August 11th Invited to work in Dr. Mark Laubach’s Research lab under a private grant Studied and performed stereotaxic surgery for optogenetics and DREADDs for behavioral assessments Performed perfusions and tissue processing for fluorescent imaging Performed immunohistochemistry Performed light and fluorescent microscopy for neuroanatomical tract tracing Performed behavioral assessments References available upon request.