ITINERARY Vanderbilt Center for Benign Urologic Diseases Scientific Retreat Student Life Center, Board of Trust Tuesday - June 26 5:00 P.M. - 6:30 P.M. 5:00-5:20 Hors d’oeuvres and Mingle 5:20-5:30 Welcome and Introduction of Keynote Speaker 5:30-6:30 6:30 p.m. Prostatic Fibrosis as Contributing Pathobiology to Lower Urinary Tract Dysfunction Simon W. Hayward, Ph.D. Jill A. Macoska, Ph.D. Adjournment Wednesday - June 27 8:00 A.M. - 5:00 P.M. 8:00-8:55 Breakfast 8:55-9:00 Welcome and Introduction 9:00-9:30 The Role of PPARγ Pathway on Bladder Function 9:30-10:00 10:00-10:30 10:30-11:00 Peter E. Clark, M.D. Robert J. Matusik, Ph.D. Past, Present, and Future of Adipose Tissue Alyssa M. Hasty, Inflammation Ph.D. Quantitative Analysis of Tumor Cell Metabolism Using Jamey D. Young, Mass Spectrometry and Computational Flux Modeling Ph.D. Break Metformin and Thiazolidinedione Use on Lower Urinary 11:00-11:30 Tract Symptoms in a National Cohort of Veterans with Diabetes Mellitus Harvey J. Murff, M.D. 11:30-12:00 12:00-12:30 Mechanisms of PPARγ-mediated Prostatic Doug W. Strand, Differentiation Ph.D. Molecular Mechanisms of Tumor Progression in A Steatotic Liver Microenvironment 12:30-1:30 Lunch 1:30-3:00 Poster Presentation 3:00-5:00 Award Presentation and Socializing 5:00 p.m. Adjournment D. Lee Gorden, M.D.