SUBSTANCE USE TRAJECTORIES OF POST-BARIATRIC SURGERY PATIENTS ENROLLED IN SUBSTANCE ABUSE TREATMENT Ashley A. Wiedemann¹, Karen K. Saules¹, John A. Hopper2, Joyce Foster-Hartsfield3, Valentina Ivezaj¹, Summar Reslan¹, Alisha Serras¹, Lorrianne Kuykendall¹, Randi Nguyen¹ & Daniel Wood.¹ Contact: awiedema@emich.edu Eastern Michigan University¹, St. Joseph Mercy Hospital2, Brighton Hospital3 Introduction Results In 2006, Brighton Hospital, a comprehensive substance abuse treatment facility, began observing increasing admissions who reported histories of bariatric surgery (Saules et al., in press). It is unknown, however, whether substance use problems typically precede or arise subsequent to bariatric surgery. Furthermore, it is unknown what variables may contribute to the onset of new substance use following bariatric surgery. The sample was predominantly White (82.4%), female (71.6%), with a mean age of 44.64 ± 9.34, mean BMI of 30.99 ± 6.55 (obese), and mean post-surgical weight loss of 161.18 ± 60.24 lbs. The average patient underwent bariatric surgery at age 39.95 ± 9.42. Many (30.1%) had no prior substance use treatment. The majority sought treatment for dependence on alcohol (60.8%). The remainder sought treatment for alcohol plus another drug (9.5%), opiates (14.9%), benzodiazepines (6.9%), multiple drugs (6.8%). Only one participant sought treatment for amphetamines. Method PROCEDURES/PARTICIPANTS: The sample for this report includes electronic medical record data of any case identified with “intestinal bypass” or “bariatric bypass.” Data were obtained from 74 chart reviews of patients admitted to Brighton Hospital’s rehabilitation, detoxification, and partial hospital between April 16, 2006 through January 14th 2010. Two participants were not included in the final analysis due to a missing date of surgery and another subject did not have dates of heavy drug/alcohol use. Χ2 (1, N = 53) = 6.36, p <.05 Discussion Data Analysis Participants were classified based on age of bariatric surgery relative to the age of first engaging in heavy drug/alcohol use. Participants were categorized as: One-sample chi-square analysis with expected values set as equal (a conservative approach) revealed significant differences between Relapsers and New Onset Users for rates of heavy opiate, Χ2 (1, N = 29) = 4.12, p <.05 and benzodiazepine use, Χ2 (1, N = 24) = 10.67, p <.001 but no difference for alcohol use Χ2 (1, N = 58) = 1.72, p =.19. A 2 X 2 chi –square analysis (ever used, yes/no) indicated that Relapsers were significantly more likely to have used alcohol Χ2 (1, N = 72) = 5.53, p <.05 and THC, Χ2 (1, N = 72) = 6.59, p <.05. Results yield unexpectedly high rates of new onset substance abuse among adults, which is uncommon (Kalaydjian et al., 2009). Results from ongoing qualitative interviews suggest that some bariatric patients with a history of heavy substance use prior to surgery (i.e., Relapsers) undergo an extended period of sobriety before receiving surgery, and consequently relapse after surgery. Future research should examine these trajectories and variables that may pose post-surgical risks among this population. Educating all patients about post-surgical risks is warranted. Bariatric surgery patients with a family history of mental illness may have an increased risk for alcohol abuse. Such patients may be vulnerable to what some refer to as “addiction transfer,” which suggests patients who receive successful treatment for one addiction (e.g., food •“New Onset Users” had no evidence of a prior addiction) may subsequently develop another to replace substance abuse history and spontaneously developed a When examining only heavy alcohol users, New Onset Users were the former (e.g., substance use). In light of the high rate of drug/alcohol problem after surgery (40.3%). significantly more likely to have a family history of mental illness, relapse, these preliminary results highlight the need for Chi-square (including one-sample chi-square) and T- yet groups did not differ on family history of substance use, as the comprehensive pre-surgical screening of substance use, Tests were conducted to explore differences among majority of the sample had a family history of use (83.6%). particularly among those with a history of substance use. Relapsers and New Onset Users. Presented at the 2010 Annual Meeting of the Society of Behavioral Medicine •“Relapsers” had a history of heavy drug/alcohol use prior to bariatric surgery and returned to some form of alcohol/drug use post-surgery (59.7%).