List of publications Papers - Refereed: 1. Jelzow A,Tachtsidis I,Kirilina E,Niessing M,Bruhl R,Wabnitz H,Heine A,Ittermann B,Macdonald R, “Simultaneous measurement of time-domain fNIRS and physiological signals during a cognitive task.” SPIE-INT SOC OPTICAL ENGINEERING, DIFFUSE OPTICAL IMAGING III, Volume 8088 (2011). 2. Walton R.D., Dilip C., Xavier L., Tachtsidis I, Bernus O., “Experimental Validation of Alternating Transillumination for Imaging Intramural Wave Propagation.” 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’11) Boston, USA (2011). 3. Payne S.J., Mohammad J., Tisdall M.M., Tachtsidis I., “Effects of arterial blood gas levels on cerebral blood flow and oxygen transport.” Biomedical Optics Express, 2(4):966-979 (2011). 4. Papademetriou M.D., Tachtsidis I., Banaji M., Elliott M.J., Hoskote A., Elwell C.E. “Regional cerebral oxygenation measured by multichannel near-infrared spectroscopy (optical topography) in an infant supported on venoarterial extracorporeal membrane oxygenation.” J Thorac Cardiovasc Surg. 141(5):e31-3 (2011). 5. Patel S., Katura T., Maki A., Tachtsidis I. “Quantification of systemic interference in optical topography data during frontal lobe and motor cortex activation: an independent component analysis.” Advances in Experimental Medicine and Biology, 915:45-51 (2011). 6. Tachtsidis I., Tisdall M.M., Pritchard C., Leung T.S., Ghosh A., Elwell C.E., Smith M. “Analysis of the Changes in the Oxidation of Brain Tissue Cytochrome c Oxidase in Traumatic Brain Injury Patients during Hypercapnoea: a Broadband NIRS Study.” Advances in Experimental Medicine and Biology, 915:9-14 (2011). 7. Gao L., Elwell C.E., Kohl-Bareis M., Gramer M., Cooper C.E., Leung T.S., Tachtsidis I. “Effects of assuming constant optical scattering on haemoglobin concentration measurements using NIRS during a Valsalva Manoeuvre.” Advances in Experimental Medicine and Biology, 915:15-20 (2011). 8. Tachtsidis I., Leung T.S., Ghosh A., Smith M., Cooper C.E., Elwell C.E. “Multi-Wavelength, Depth Resolved, Scattering and Pathlength Corrected in vivo Near-Infrared Spectroscopy of Brain Tissue.” Biomedical Optics (BIOMED) 2010 paper: BTuB7 OSA Technical Digest (CD) 9. Tachtsidis I., Gao L., Leung T.S., Kohl-Bareis M., Cooper C.E., Elwell C.E. “A hybrid multi-distance phase and broadband spatially resolved spectrometer and algorithm for resolving absolute concentrations of chromophores in the near-infrared light spectrum.” Advances in Experimental Medicine and Biology, 662:169-175 (2010). 10. Tachtsidis I., Koh P.H., Stubbs C., Elwell C.E. “Functional optical topography analysis using statistical parametric mapping (SPM) methodology with and without physiological confounds.” Advances in Experimental Medicine and Biology, 662:237-243 (2010). 11. Banaji M., Mallet A., Elwell C.E, Nicholls P., Tachtsidis I., Smith M., Cooper C.E. “Modelling of mitochondrial oxygen consumption and NIRS detection of cytochrome oxidase redox state.” Advances in Experimental Medicine and Biology, 662:285-291 (2010). 12. Papademetriou M.D., Tachtsidis I., Elliott M., Hoskote A., Elwell C.E. “Cerebral and somatic tissue oxygenation analysis in children supported on ECMO for cardiorespiratory failure.” Advances in Experimental Medicine and Biology, 662:447-453 (2010). 13. Leung T.S., Tachtsidis I., Tisdall M.M., Pritchard C., Smith M., and Elwell C.E. Reply to 'Comment on "Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler"' Physiological Measurement 30:L13-L14 (2009). 14. Tisdall M.M., Taylor C., Tachtsidis I., Leung T.S., Pritchard C., Elwell C.E., Smith M. “The effect on cerebral tissue oxygenation index of changes in the concentrations of inspired oxygen and end tidal carbon dioxide in healthy adult volunteers.” Anesthesia & Analgesia, 109(3):906-13 (2009). 15. *Tachtsidis I., Tisdall M.M., Leung T.S., Pritchard C., Cooper C.E., Smith M., Elwell C.E. “The relationship between brain tissue haemodynamics, oxygenation and metabolism in the healthy human adult brain during hyperoxia and hypercapnea.” Advances in Experimental Medicine and Biology, 645, 315-320, (2009). 16. *Tachtsidis I., Leung T.S., Chopra A., Koh P.H., Reid C.B., Elwell C.E. “False positives in functional near-infrared topography.” Advances in Experimental Medicine and Biology, 645, 307-314, (2009). 17. Leung T.S., Tachtsidis I., Tisdall M.M., Pritchard C., Smith M., and Elwell C.E. “Estimating a modified Grubb’s exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler.” Physiological Measurement 30, 1-12 (2009). 18. *Tachtsidis I., Kohl-Bareis M., Leung T. S., Gramer M., Tahir B., Cooper C. E., Elwell C.E., “A hybrid multi-distance phase and broadband spatially resolved algorithm for resolving absolute concentrations of chromophores in the near-infrared light spectrum: application on to dynamic phantoms.” Biomedical Topical Meetings (The Optical Society of America), BSuE76, Florida, USA (March 2008). 19. Leung T. S., Tachtsidis I., Tisdall M., Smith M., Pritchard C., Cooper C. E., Elwell C.E., “Investigating cross-talk in cytochrome c oxidase using near-infrared spectroscopy in a two layered model.” Biomedical Topical Meetings (The Optical Society of America), BSuE77, Florida, USA (March 2008). 20. *Tachtsidis I., Leung T.S., Tisdall M.M., Devendra P., Smith M., Delpy D.T., Elwell C.E. “Investigation of frontal cortex, motor cortex and systemic haemodynamic changes during anagram solving.” Advances in Experimental Medicine and Biology 614, 21-28 (2008). 21. *Tachtsidis I., Leung T.S., Devoto L., Delpy D.T., Elwell C.E. “Measurement of frontal lobe functional activation and related systemic effects: a near-infrared spectroscopy investigation.” Advances in Experimental Medicine and Biology 614, 397- 403 (2008). 22. *Tachtsidis I., Tisdall M., Delpy D.T., Smith M., Elwell C.E., “Measurement of cerebral tissue oxygenation in young healthy volunteers during acetazolamide provocation: a transcranial Doppler and near-infrared spectroscopy investigation.” Advances in Experimental Medicine and Biology 614, 389-396 (2008). 23. Tisdall M.M., Tachtsidis I., Leung T.S., Elwell C.E. and Smith M. “Changes in the attenuation of near-infrared spectra by the healthy adult brain during hypoxaemia cannot be accounted for solely by changes in the concentrations of oxy- and deoxy- haemoglobin.” Advances in Experimental Medicine and Biology 614, 217-225 (2008). 24. Leung T.S., Tisdall M.M., Tachtsidis I., Smith M., Delpy D.T., Elwell C.E. “Cerebral tissue oxygen saturation calculated using low frequency haemoglobin oscillations measured by near infrared spectroscopy in adult ventilated patients, Advances in Experimental Medicine and Biology 614, 235244 (2008). 25. Tisdall M.M., Tachtsidis I., Leung T.S., Elwell C.E., Smith M. “Normobaric hyperoxia increases cerebral aerobic metabolism after traumatic brain injury.” Journal of Neurosurgery, 109, 424-432 (2008). 26. Tisdall M.M., Tachtsidis I., Leung T.S., Elwell C.E. and Smith M. “Near infrared spectroscopic quantification of changes in the concentration of oxidized cytochrome oxidase in the healthy human brain during hypoxemia.” Journal of Biomedical Optics, 12(2):024002, (2007). 27. Leung T.S., Tachtsidis I., Tisdall M., Smith M., Delpy D.T., Elwell C.E. “Theoretical investigation of measuring cerebral blood flow using a bolus injection of the indocyanine green detected by nearinfrared spectroscopy in the adult human head.” Applied Optics, 46(10):1604-14, (2007). 28. *Tachtsidis I., Tisdall M.M., Leung T.S., Cooper C.E., Delpy D.T., Smith M., Elwell C.E. “Investigation of in-vivo measurement of cerebral cytochrome-c-oxidase redox changes using nearinfrared spectroscopy in patients with orthostatic hypotension.” Physiological Measurements, 28: 199211, (2007). 29. Rowley A.B., Payne S.J., Tachtsidis I., Ebden M.J., Whiteley J.P., Gavaghan D.J., Tarassenko L., Smith M., Elwell C.E. and Delpy D.T. “Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross-correlation.” Physiological Measurements, 28(2), (2007). 30. Hunt K., Tachtsidis I., Bleasdale-Barr K., Elwell C., Mathias C., Smith M., “Changes in Cerebral Oxygenation and Haemodynamics during Postural Blood Pressure Changes in Patients with Autonomic Failure” Physiological Measurements, 27(9):777-785, (2006). 31. Leung T.S., Tachtsidis I., Smith M., Delpy D.T., Elwell C.E. “Measurement of the absolute optical properties and cerebral blood volume of the adult human head with hybrid differential and spatially resolved spectroscopy” Physics In Medicine and Biology 51(3):703-17, (2006). 32. *Tachtsidis I., Leung T.S., Oliver C., Henty J.R., Jones H., Smith M., Delpy D.T., Elwell C.E. “Quantification of adult cerebral blood volume using tissue oxygenation index.” Advances in Experimental Medicine and Biology, 578: 237-243, (2006). 33. Leung T.S., Tachtsidis I., Oliver C., Henty J.R., Jones H., Smith M., Delpy D.T., Elwell C.E. “Investigation of apparent oxygen saturation from the pulsatile signals measured on adult heads using Near Infrared Spectroscopy.” Advances in Experimental Medicine and Biology, 578: 209-215, (2006). 34. *Tachtsidis I., Tisdall M., Leung T.S., Delpy D.T., Smith M., Elwell C.E., “Cerebral blood flow assessment with indocyanine green bolus transit detection by near-infrared spectroscopy before and after acetazolamide challenge in humans.” in Biomedical Optics 2006 Technical Digest (Optical Society of America, Washington, DC, 2006), ME67, (2006). 35. Leung T.S., Tachtsidis I., Tisdall M., Arridge S.R., Delpy D.T., Smith M., Elwell C.E., “Modelling of indocyanine green boluses with a finite element model of the adult human head and the Fick principle.” in Biomedical Optics 2006 Technical Digest (Optical Society of America, Washington, DC, 2006), MC6, (2006). 36. Tisdall M., Tachtsidis I., Elwell C.E., Smith M., “Changes in concentrations of oxidised cytochrome oxidase measured using both broadband and four wavelength near infrared spectroscopy reflect changes in oxygen delivery during hypoxaemia in healthy volunteers.” in Biomedical Optics 2006 Technical Digest (Optical Society of America, Washington, DC, 2006), ME66, (2006). 37. Banaji M., Tachtsidis I., Delpy D., Baigent S. “A physiological model of cerebral blood flow control." Mathematical Biosciences, 194(2):125-173, (2005). 38. *Tachtsidis I., Elwell C.E., Leung T.S., Bleasdale-Barr K., Hunt K., Toms N., Smith M., Mathias C.J., Delpy D.T. “Rate of change in cerebral oxygenation and blood pressure in response to passive changes in posture: a comparison between Pure Autonomic Failure patients and Controls.” Advances in Experimental Medicine and Biology, 566:187-193, (2005). 39. Wolff C.B., Checkley S.K., Bhageerutty G., Bhatt H., Johnston A., Collier D.J., Tachtsidis I., Garvie N., Rosenberg M.E., “Circulation time in man from lung to periphery as an indirect index of cardiac output.” Advances in Experimental Medicine and Biology, 566:311-6, (2005). 40. *Tachtsidis I., Elwell C.E., Leung T.S, Lee C.W., Smith M., Delpy D.T., “Investigation of cerebral haemodynamics by near infrared spectroscopy in young healthy volunteers reveals posture dependent spontaneous oscillations.” Physiological Measurement, 25(2):437-445, (2004). 41. *Tachtsidis I., Elwell C.E., Lee C.W., Leung T.S, Smith M., Delpy D.T. “Spectral characteristics of spontaneous oscillations in cerebral haemodynamics are posture dependent.” Advances in Experimental Medicine and Biology, 540:31-36, (2004). 42. *Tachtsidis I., Cooper C.E., McGown A.D., Makker H., Delpy D.T., Elwell C.E. “Changes in cerebral total haemoglobin volume and cytochrome oxidase redox state during deep apnoeas in patients with obstructive sleep apnoea.” Biomedical Topical Meetings on CD-ROM (The Optical Society of America, Washington, DC), WF6 (2004). 43. Leung T.S, Elwell C.E., Tachtsidis I., Henty J.R., Delpy D.T. “Measurement of optical properties in the adult human head with spatially resolved spectroscopy and changes of postures.” Advances in Experimental Medicine and Biology, 540:13-18, (2004). Awaiting Publication/Submitted 44. Ghosh A., Tachtsidis I., Kolyva C., Cooper C.E., Smith M., Elwell C.E. "Use of a Hybrid Optical Spectrometer for the Measurement of Changes in Oxidized Cytochrome c Oxidase Concentration and Tissue Scattering During Functional Activation." In Press, Advances in Experimental Medicine and Biology 45. Papademetriou M.D., Tachtsidis I., Banaji M., Elliott M.J., Hoskote A., Elwell C.E. “Optical Topography to measure variations in Regional Cerebral Oxygenation in an Infant supported on venoarterial Extra-Corporeal Membrane Oxygenation.” In Press, Advances in Experimental Medicine and Biology 46. Moroz T., Banaji M., Tisdall M., Cooper C.E., Elwell C.E., Tachtsidis I. “Development of a Model to Aid NIRS Data Interpretation: Results from a Hypercapnia Study in Healthy Adults.” In Press, Advances in Experimental Medicine and Biology 47. Kolyva C., Tachtsidis I., Ghosh A., Cooper C.E., Smith M., Elwell C.E. “Systematic investigation of changes in cerebral cytochrome c oxidase concentration during frontal lobe activation in healthy adults.” Submitted JBO Book Chapters 48. Tachtsidis I. “OTHER NEUROIMAGING METHODS – BRAIN OPTICAL IMAGING & MORE.” The Atlas of Epilepsies edited by Chrysostomos Panayiotopoulos, Publisher Springer ISBN 978-1-84882127-9, pp813-822 (2010) Conference Abstracts (1 page) – Refereed 49. Moroz T., Banaji M., Robertson N.J., Cooper C.E., Tachtsidis I. “Computational modelling of oxygen deprivation in the neonatal piglet brain.” International Conference on Systems Biology, Heidelberg, Germany, 2011 50. Zhu T., Ahmed J., Tachtsidis I., “Monitoring brain oxygenation and metabolism in the adult during frontal lobe functional activation using a novel seven wavelength near-infrared spectrometer.” Brain 2011, Barcelona, Spain, May 2011 51. Moroz T., Banaji M., C.E. Cooper, N. Robertson, Tachtsidis I. "Computational modelling of the piglet brain to simulate near infrared spectroscopy and magnetic resonance spectroscopy data collected during physiologic insults." Brain 2011, Barcelona, Spain, May 2011 52. Tachtsidis I., Bainbridge A., Faulkner S., Mahoney S., Price D., Thomas D., Cady E., Robertson N., Golay X. "Fusion of near-infrared and magnetic resonance spectroscopy delivers novel multimodal investigation of neonatal hypoxic-ischaemic brain injury.” Brain 2011, Barcelona, Spain, May 2011 53. Highton D.T., Ghosh A., Bal J., Tachtisidis I., Kolyva C., Elwell C.E., Smith M. “Near-infrared spectroscopy as a measure of vascular reactivity in brain injury.” Brain 2011, Barcelona, Spain, May 2011 54. Panovska-Griffiths J., Banaji M., Tachtsidis I., Moroz T., Cooper C.E., Elwell C.E. “The effect of hypocapnoea and hypercapnoea on cerebral haemodynamics, oxygenation and metabolism: combining modelling and experimental approaches.” Brain 2011, Barcelona, Spain, May 2011 55. Payne S.J., Mohammad J., Tisdall M.M., Tachtsidis I., “Effects of arterial blood gas levels on cerebral blood flow and oxygen transport.” Brain 2011, Barcelona, Spain, May 2011 56. Kirilina E., Jelzow A., Heine A., Niessing M., Jacobs A., Wabnitz H., Macdonald R., Bruehl R., Ittermann B., Tachtsidis I. “The physiological origin of task-evoked artifacts in functional Near Infrared Spectroscopy.” 17TH Annual Meeting of the Organisation on Human Brain Mapping, June 2011 57. E. Kirilina, A. Jelzow, R. Bruehl, A. Heine, M. Niessing, A. M. Jacobs, B. Ittermann, H. Wabnitz, R. Macdonald, and I. Tachtsidis "Physiological origin of systemic artifacts in functional near infrared spectroscopy as revealed by fMRI." ISMRM 2011, Montreal, Canada, May 2011 58. Bainbridge A., Tachtsidis I., Faulkner S., Mahoney S., Price D., Thomas D., Cady E., Robertson N., Golay X. “Combined 1H MRS and Near-Infrared Spectroscopy Measurements of Cerebral Blood Volume, Oxygenation, Cytochrome Oxidase, and Intracellular Metabolites During Perinatal HypoxiaIschaemia” ISMRM 2011, Montreal, Canada, May 2011 59. Jelzow A., Tachtsidis I., Kirilina E., Niessing M., Brühl R., Wabnitz H., Heine A., Ittermann B., Macdonald R. “Simultaneous measurement of time-domain fNIRS and physiological signals during a cognitive task.” SPIE/OSA European Conference in Biomedical Optics Munich, Germany, May 2011 60. Faulkner S., Bainbridge A., Tachtsidis I., Mahoney S., Price D., Thomas D., Cady E., Golay X., Robertson N. “Simultaneous 1H MRS and Near-Infrared Spectroscopy Measurements of Cerebral Blood Volume, Oxygenation, Cytochrome Oxidase, and Intracellular Metabolites During Perinatal Hypoxia-Ischemia” Annual meeting of PAS, Denver, USA, 2011 61. Powell E., Faulkner S., Tachtsidis I., Bainbridge A., Price D., Andorka C., Mahoney S., Cady E., Golay X., Robertson N. “Combined 1H magnetic resonance spectroscopy and near-infrared spectroscopy measurements of cerebral blood volume, oxygenation, cytochrome oxidase, and intracellular metabolites during perinatal hypoxia-ischaemia” Annual meeting of ESPR, Newcastle, UK, 2011 62. Papademetriou M.D., Tachtsidis I., Elliott M.J., Hoskote A., Elwell C.E. “Multichannel Cerebral Near Infra-Red Spectroscopy (NIRS) in neonates supported on ECMO” 6th World Congress on Pediatric Critical Care, Sydney, Australia. March 2011 63. Ikonomopoulos J, Liandris E, Andreadou M, Tachtsidis I, Gazouli M Applied nanotechnology for the detection of mycobacterial nucleic and antigenic targets. 31st Annual Congress of the European Society of Mycobacteriology (ESM 2010) July 4th-7th, 2010 in Bled, Slovenia. 64. Highton D., Ghosh A., Tachtsidis I., Kolyva C., Elwell C., Smith M. “A Comparison Between Pressure Reactivity Index, Mean Velocity Index, and Near Infrared Spectroscopy in Brain Injury.” J Neurosurg Anesthesiol 2010 vol. 22 (4) pp. 419-420 65. *Tachtsidis I., Pritchard C., Tisdall M., Leung T., Elwell C., Smith M. "Hypercapnea does not consistently increase the oxidation of cytochrome c oxidase in traumatic brain injury." Brain 09, Chicago, USA, (2009). 66. Pritchard C, Toma A, Tisdall M, Tachtsidis I, Leung T, Elwell C, Smith M. “Hypercapnia does not increase aerobic metabolism in the injured human brain.” JICS 10:63 (2009). 67. Papademetriou M.D., Tachtsidis I., Leung T.S., Elliott M.J., Elwell C.E., Hoskote A. “Cerebral and peripheral tissue oxygenation by near-infrared spectroscopy in children supported on ECMO for cardio-respiratory failure.” ESPNIC 2009, Verona, Italy (2009). 68. Iuculano T., Tachtsidis I., Hui-Koh P, Elwell C.E., Butterworth B. “Functional Optical Signal Analysis of Calculation and Language Laterality.” CNS, Chicago, USA (2009). 69. Pritchard C, Leung T, Tachtsidis I, Tisdall M, Elwell C, Smith M. “Comparison of cerebral oxygen extraction fraction measured using jugular venous oxygen saturation and near infrared spectroscopy.” J Neurosurg Anesthesiol 20: 303-4 (2008). 70. Pritchard C., Leung T. S., Tisdall M., Tachtsidis I., Elwell C.E., Smith M, “Non-invasive assessment of cerebral autoregulation using near-infrared spectroscopy.” Anesthesia and Analgesia 106: S116 (2008) 71. Smith M., Leung T., Tisdall M., Tachtsidis I., Elwell C., “Measurement of cerebral oxygen extraction fraction using near infrared spectroscopy in healthy adult volunteers.” Journal of Neurosurgical Anesthesiology; 19: 324 (2007). 72. *Tachtsidis I., Tisdall M., Leung T.S., Pritchard C., Smith M., Elwell C.E., “Hyperoxia and hypercapnea increase the concentration of oxidised cytochrome c oxidase in the healthy human adult brain.” Brain 07, Osaka, Japan, (2007). 73. Tisdall M., Tachtsidis I., Leung T.S., Elwell C.E., Smith M., “Changes in cerebral tissue oxygen saturation measured by near infrared spectroscopy do not only reflect changes in oxygenation.” J. Neurosurg. Anesthesiol.; 19: 152 (2007). 74. Tisdall M, Tachtsidis I, Elwell CE, Kitchen N, Smith M. “Near infrared spectroscopy can detect reduced cerebral oxygen utilisation during hypoxaemia in healthy volunteers.” Br J Neurosurg 20:444 (2006) 75. Tisdall M., Tachtsidis I., Leung T.S., Elwell C.E., Smith M., “Non-invasive measurement of changes in cerebral mitochondrial oxygenation in human volunteers.” Meeting of Society of Neurosurgical Anaesthesia and Critical Care, Chicago, Illinois, U.S.A. (October 2006). 76. *Tachtsidis I., M. Banaji, M. Tisdall, M. Smith, S. Baigent, C.E. Elwell, D.T. Delpy, “The Application of a Model of Human Brain Circulation to Head Trauma Patients: A Computational Systems Biology Approach.” Gordon Conference Oxford UK (August 2006). 77. Leung TS, Tachtsidis I, Tisdall M, Smith M, Elwell CE, Delpy DT. “Measurement of cerebral blood flow with indocyanine green and NIRS, before and after the administration of acetazolamide.” Br J Neurosurg 20:335 (2006). 78. Tisdall M, Tachtsidis I, Leung TS, Elwell CE, Smith M. “Non-invasive measurement of changes in cerebral mitochondrial oxygenation in human volunteers.” J Neurosurg Anesthesiol;18:299-300 (2006). 79. Taylor C., Coward L., Tachtsidis I., Tisdall M., Elwell C.E., Brown M., Smith M., “Measurement of Cerebral Tissue Oxygenation Using Near Infrared Spectroscopy (NIRS) in Stroke Patients.” Journal of Neurosurgical Anaesthesiology, 17(3):157-158, (July 2005) 80. *Tachtsidis I., Jones H., Oliver C., Delpy D.T., Smith M., Elwell C.E., “Investigation of the changes in cerebral tissue oxygenation measured with near infrared spectroscopy in response to moderate hypercapnia.” Journal of Cerebral Blood Flow & Metabolism, 25, S193, (2005) 81. Tisdall M, Tachtsidis I, Elwell CE, Smith M. “Non-invasive monitoring of carbon dioxide reactivity: spatially resolved near infrared spectroscopy and transcranial Doppler.” Eur J Anesth; 22:5-6 (2005). 82. Tisdall M., Tachtsidis I., Bleasdale-Barr K., Mathias C.J., Delpy D.T., Elwell C.E., Smith M., “Investigation of the cerebral haemoglobin and cytochrome signals using near infrared spectroscopy 83. 84. 85. 86. 87. 88. 89. during head up tilt in patients with orthostatic hypotension.” Journal of Cerebral Blood Flow & Metabolism, 25, S571, (2005) *Tachtsidis I., Leung T.S., Oliver C., Jones H., Elwell C.E., Smith M., “Non-invasive measurement of absolute cerebral blood volume in adults using a tissue oxygen index.” J Neurosurg Anesthesiol, 16: 372 (2004). *Tachtsidis I., Banaji M. “A computational model of the cerebral circulation: model predictions with experimental data during a CO2 challenge.” Proceedings of IPEM Annual Scientific Meeting in York (2004). Banaji M., Tachtsidis I. “A computational model of the cerebral circulation: model construction and theoretical considerations.” Proceedings of IPEM Annual Scientific Meeting in York (2004). Smith M., Tachtsidis I., Elwell C.E., Leung T.S., Delpy D.T., “Posture Dependence of Spontaneous Oscillations in Cerebral Haemodynamics.” Anesth. Analg. , 98: S140 (2004). Banaji M., Tachtsidis I., Delpy D., Baigent S. “A physiological model of the human brain circulation” Proceedings of IPEM meeting on the modelling of blood flow in cardiovascular disease in York (2003). Bleasdale-Barr K., Tachtsidis I., Hunt K., Toms N., Henty J.R., Elwell C.E., Delpy D.T., Smith M. and Mathias C.J. “Changes in Cerebral oxygen saturation on postural change in patients with autonomic failure and orthostatic hypotension and controls.” Clin Auton Res, 12:409-410, (2002). Hunt K., Tachtsidis I., Bleasdale-Barr K., Thoms N., Henty J., Elwell C., Mathias C., Smith M. “Changes in Cerebral Tissue Oxygenation during Postural Hypotension in Patients with Autonomic Failure” Journal of Neurosurgical Anaesthesiology, 14(4):347, (2002).