MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms. HST.583: Functional Magnetic Resonance Imaging: Data Acquisition and Analysis, Fall 2008 Harvard-MIT Division of Health Sciences and Technology Course Director: Dr. Randy Gollub. 2. T1, T2 and T2* Measurements Background To calculate T1 values of the tissue we will be using an inversion recovery turbo spin echo sequence. We will be sampling the magnetization as a function of the inversion time (TI). The observed signal intensity is given by the following equation: S(t) ∝ [1 − 2 exp(−TI / T1)] (1) To obtain the transverse relaxation time, T2, values in the brain a series of spin echo images will be acquired by stepping through a range of TEs. The image intensity is given by the following equation: S(t) ∝ exp(−TE / T 2) (2) T2star (T2*) is the time constant that describes the decay of the transverse magnetization including local magnetic field inhomogeneities. T2* is an important relaxation time for functional studies because it is related to the amount of deoxygenated hemoglobin present in the brain. To determine the T2* values in gray, white matter and CSF, we will be using a gradient echo sequence and the signal is described by: S(t) ∝ exp(−TE / T 2*) (3) Experiments In this exercise we will acquire and evaluate human data in order to characterize T1, T2 and T2* values in brain tissue compartments. Various sequences will be used with the imaging parameters manipulated so that they provide the appropriate contrast weightings. T1 measurements Acqusition: Total scan time: 5m 38sec A. Inversion Recovery Turbo Spin Echo (tse_IR) sequence with TR=3000ms, FOV=240x240, matrix=96x128, repeated for multiple inversion times TI=200, 300, 400, 500, 600, 700, 800, 1000, 1300, 1500, 1700, 2000, 2200 ms. 1. 2. 3. 4. Load all the images on the viewer. Draw ROIs in gray matter areas. Record the mean signal values in Table 1 for each inversion time and ROI. Repeat steps 1-3 for regions of white matter and CSF. Lab Question 6 : Draw the measured signal as a function of inversion time for each of the tissue compartments. Calculate the T1 for gray, white matter and CSF by fitting Eq. (1) to your data. Hint: you will need to use a nonlinear fitting function such as nlinfit in matlab to accomplish this. T2 measurements Acqusition: Total scan time: 9m 42sec B. SE sequence with TR=4000ms, FOV=220x220, matrix=192x192, 8 echo times in a range between 14.3ms and 114.4ms and inter-echo spacing 14.3 ms. 5. 6. 7. 8. Load all the images on the viewer. Draw ROIs in gray matter areas. Record the mean signal values in Table 2 for each echo time and ROI. Repeat steps 1-3 for regions of white matter and CSF. Lab Question 7 : Draw the measured signal as a function of echo time for each of the tissue compartments. Calculate the T2 for gray, white matter and CSF by fitting Eq. (2) to your data. T2* measurements Acqusition: Total scan time: 11sec C. 2D FLASH sequence with TR=100msec, FOV=256x256, matrix=128x128, and multi contrast with echo times TE=6, 10, 15, 20, 30, 50, 70, 80 msec. 9. Load all the images on the viewer. 10. Draw ROIs in gray matter areas. 11. Record the mean signal values in Table 3 for each echo time and ROI. 12. Repeat steps 1-3 for regions of white matter and CSF. Lab Question 8 : Draw the measured signal as a function of echo time for each of the tissue compartments. Calculate the T2* of gray and white matter and CSF by fitting Eq. (3) to your data. Lab Question 9 : According to your measurements how do T2 and T2* compare for the same tissue compartment? Did you expect these findings? Explain why. Table 1 – T1 Measurements TI (ms) 200 300 400 500 600 700 800 1000 1300 1500 1700 2000 2200 Gray White Matter Matter CSF Table 2 – T2 Measurements TE (ms) Gray White Matter Matter CSF 14.3 28.6 42.9 57.2 71.5 85.8 100.1 114.4 Table 3 – T2* Measurements TE (ms) 6 10 15 20 30 50 70 80 Gray White Matter Matter CSF 3. Distortion in EPI due to B0 Inhomogeneity Background The echo-planar image (EPI) is distorted due to local field gradients present in the head during imaging. Since the acquisition of k-space data is very asymmetric in EPI, with the readout direction points (kx) collected quickly and the phase encode steps (ky) relatively slowly, the distortion is essentially entirely in the y direction (phase encode direction). The relative distortion between the two directions can be estimated from the relative speed of the acquisition. In kx, at a typical readout BW (say 2.2kHz/pixel or 140kHz in frequency across the 64 pixel image), the dwell time (time between kx samples) is 7.1μs. The ky sampling rate is slower because of the zig-zag trajectory, and is about 64 times slower. This gives a sampling spacing of 64 * 7.1μs = 0.45ms. We call this .the "echo spacing", (esp), of the sequence, the time between gradient echos (acquisition of the kx=0 point). 1 The effective "bandwidth" in the phase encode direction is therefore across the esp image or 1/64*esp = 34.7Hz/pixel. Therefore a B0 shift which induces a 34.7Hz frequency shift will induce a shift in this region of 1pixel. The frequency shifts in the "bad susceptibility" regions of the brain are easily in the 100Hz range. Therefore, the principle metric of how distorted the EPI sequence will be is its effective echo-spacing. For conventional echo-planar imaging, this is basically limited by the gradient slew rate and amplitude. Using parallel acceleration such as SENSE or GRAPPA effectively decreases the esp by a factor of the acceleration factor, (i.e. 2 or 3 fold). Experiments In this lab we will acquire images with different effective esp and compare the distortion in the brain. Acquisition : 1) epi_esp730: voxel size = 3.1 x 3.1 x 3.1, Matrix size = 64x64, BW=1502Hz/px, ESP=0.73ms, effective esp =0.73ms 2) epi_esp460: voxel size = 3.1 x 3.1 x 3.1, Matrix size = 64x64, BW=2520Hz/px, ESP=0.46ms, effective esp =0.46ms 3) epi_esp480_grappa: voxel size = 3.1 x 3.1 x 3.1, Matrix size = 64x64, BW=2520Hz/px, ESP=0.48ms, effective esp =0.46ms Lab Question 10: Estimate the distortion in frontal lobes by measuring distance on the scanner to some reference feature. Plot the distortion in mm as a function of effective esp. SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\tse_IR1 TA: 0:26 Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements PAT: Off Voxel size: 1.9×1.9×5.0 mm Off Off On 1 50 % R0.7 A10.8 H12.2 T > C-10.3 R >> L 90.00 deg 0% 240 mm 75.0 % 5.0 mm 3000 ms 12 ms 1 1 None HEA;HEP Contrast MTC Magn. preparation TI Freeze suppressed tissue Flip angle Fat suppr. Fat sat. mode Water suppr. Restore magn. Off Slice-sel. IR 200 ms Off 180 deg None Strong None Off ------------------------------------------------------------------------------------ Resolution Base resolution Phase resolution Phase partial Fourier Trajectory Interpolation Short term Real 1 Each measurement 128 100 % Off Cartesian Off ------------------------------------------------------------------------------------ PAT mode Matrix Coil Mode None Auto (CP) ------------------------------------------------------------------------------------ Image Filter Distortion Corr. Prescan Normalize Normalize Geometry Multi-slice mode Series Off Off Off Off SIEMENS: tse Off Off Interleaved Interleaved ------------------------------------------------------------------------------------ Special sat. None ------------------------------------------------------------------------------------ System Body HEP HEA Off On On ------------------------------------------------------------------------------------ Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Save uncombined Coil Combine Mode Auto Coil Select Off single Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE Averages Concatenations Filter Coil elements Averaging mode Reconstruction Measurements Multiple series Raw filter Elliptical filter Off On Off On Off Off Rel. SNR: 1.00 REF H 0 mm S - C - T R >> L A >> P F >> H Off Adaptive Combine Default ------------------------------------------------------------------------------------ Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H Physio 1st Signal/Mode Tune up Off Off Off 337.166 V Auto Isocenter Transversal 0.00 deg 350 mm 263 mm 350 mm None ------------------------------------------------------------------------------------ Dark blood Off ------------------------------------------------------------------------------------ Resp. control Off Inline Subtract Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Off Off Off Off Off Off Off Off Off On Sequence Introduction Dimension Compensate T2 decay Reduce Motion Sens. Contrasts Bandwidth Flow comp. Allowed delay Echo spacing On 2D Off Off 1 130 Hz/Px No 0s 11.7 ms 1/+ SIEMENS MAGNETOM TrioTim syngo MR B15 ------------------------------------------------------------------------------------ Define Turbo factor Echo trains per slice RF pulse type Gradient mode Turbo factor 15 7 Normal Fast 2/+ SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\se_mc TA: 9:42 PAT: Off Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE 1 TE 2 TE 3 TE 4 TE 5 TE 6 TE 7 TE 8 Averages Concatenations Filter Coil elements Contrast MTC Magn. preparation Flip angle Fat suppr. Fat sat. mode Water suppr. Voxel size: 1.1×1.1×5.0 mm Off Off On Off single Resolution Base resolution Phase resolution Phase partial Fourier Interpolation 1 100 % R0.7 A10.8 H12.2 T > C-10.3 A >> P 0.00 deg 0 % 220 mm 100.0 % 5.0 mm 4000 ms 14.3 ms 28.6 ms 42.9 ms 57.2 ms 71.5 ms 85.8 ms 100.1 ms 114.4 ms 1 1 Raw filter HEA;HEP Off None 180 deg None Strong None Short term Magnitude 1 Each measurement 192 100 % 6/8 Off ------------------------------------------------------------------------------------ PAT mode Matrix Coil Mode None Auto (CP) ------------------------------------------------------------------------------------ Image Filter Geometry Multi-slice mode Series SIEMENS: se_mc Off Off Off On Weak 25 Off Interleaved Interleaved ------------------------------------------------------------------------------------ Special sat. System Body HEP HEA None Off On On ------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------ Averaging mode Reconstruction Measurements Multiple series Distortion Corr. Prescan Normalize Normalize Raw filter Intensity Slope Elliptical filter Off On Off On Off Off Rel. SNR: 1.00 Off Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Save uncombined Coil Combine Mode Auto Coil Select REF H 0 mm S - C - T R >> L A >> P F >> H Off Adaptive Combine Default ------------------------------------------------------------------------------------ Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H Physio 1st Signal/Mode Tune up Off Off Off 337.166 V Auto Isocenter Transversal 0.00 deg 350 mm 263 mm 350 mm None ------------------------------------------------------------------------------------ Dark blood Off Inline Subtract Liver registration Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Off Off Off Off Off Off Off Off Off Off On Sequence Introduction Contrasts Bandwidth Allowed delay On 8 202 Hz/Px 0 s ------------------------------------------------------------------------------------ RF pulse type 3/+ Normal SIEMENS MAGNETOM TrioTim syngo MR B15 Gradient mode Fast 4/+ SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\T2star_8echos TA: 0:11 Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements PAT: Off Voxel size: 2.0×2.0×5.0 mm Off single 1 20 % R0.7 A10.8 H12.2 T > C-10.3 A >> P 0.00 deg 0 % 256 mm 100.0 % 5.0 mm 100 ms 6.00 ms 10.00 ms 15.00 ms 20.00 ms 30.00 ms 50.00 ms 70.00 ms 80.00 ms 1 1 Raw filter HEA;HEP Contrast MTC Magn. preparation Flip angle Fat suppr. Water suppr. Off None 15 deg None None Long term Magnitude 1 Each measurement 128 100 % 6/8 Off ------------------------------------------------------------------------------------ PAT mode Matrix Coil Mode Saturation mode Special sat. Sequential Interleaved Standard None ------------------------------------------------------------------------------------ System Body HEP HEA None Auto (CP) Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Save uncombined Coil Combine Mode Auto Coil Select Off On On REF H 0 mm S - C - T R >> L A >> P F >> H Off Adaptive Combine Default ------------------------------------------------------------------------------------ Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H Physio 1st Signal/Mode Segments Tune up Off Off Off 337.166 V Auto Isocenter Transversal 0.00 deg 350 mm 263 mm 350 mm None 1 ------------------------------------------------------------------------------------ Dark blood Off ------------------------------------------------------------------------------------ Resp. control Inline Subtract Liver registration Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Off Off Off Off Off Off Off Off Off Off Off On ------------------------------------------------------------------------------------ Wash - In Wash - Out TTP ------------------------------------------------------------------------------------ Image Filter Distortion Corr. Off Off On Weak 25 Off ------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------ Resolution Base resolution Phase resolution Phase partial Fourier Interpolation Geometry Multi-slice mode Series SIEMENS: gre ------------------------------------------------------------------------------------ Off Off On Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE 1 TE 2 TE 3 TE 4 TE 5 TE 6 TE 7 TE 8 Averages Concatenations Filter Coil elements Averaging mode Reconstruction Measurements Multiple series Prescan Normalize Normalize Raw filter Intensity Slope Elliptical filter Off On Off On Off Off Rel. SNR: 1.00 Off Off 5/+ Off Off Off SIEMENS MAGNETOM TrioTim syngo MR B15 PEI MIP - time Sequence Introduction Dimension Phase stabilisation Asymmetric echo Contrasts Bandwidth 1 Bandwidth 2 Bandwidth 3 Bandwidth 4 Bandwidth 5 Bandwidth 6 Bandwidth 7 Bandwidth 8 Flow comp. 1 Flow comp. 2 Flow comp. 3 Flow comp. 4 Flow comp. 5 Flow comp. 6 Flow comp. 7 Flow comp. 8 Readout mode Allowed delay Off Off On 2D Off Off 8 300 Hz/Px 300 Hz/Px 300 Hz/Px 300 Hz/Px 300 Hz/Px 300 Hz/Px 300 Hz/Px 300 Hz/Px No No No No No No No No Bipolar 0 s ------------------------------------------------------------------------------------ RF pulse type Gradient mode Excitation RF spoiling Normal Fast Slice-sel. On 6/+ SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\epi_esp730 TA: 2.0 s PAT: Off Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements Voxel size: 3.1×3.1×3.1 mm Off On Off On Off Off Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Coil Combine Mode Auto Coil Select Off 90 deg Fat sat. ------------------------------------------------------------------------------------ Long term Magnitude 1 0 ms Off 64 100 % Off Off Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H None Auto (CP) BOLD GLM Statistics Dynamic t-maps Starting ignore meas Ignore after transition Model transition states Temp. highpass filter Threshold Paradigm size Meas Motion correction Spatial filter Off Off 0 0 Off Off 4.00 1 Baseline Off Off Sequence Introduction Bandwidth Free echo spacing Echo spacing Off 1502 Hz/Px Off 0.73 ms ------------------------------------------------------------------------------------ EPI factor RF pulse type Gradient mode 64 Normal Fast ------------------------------------------------------------------------------------ Dummy Scans Off Off On Off Off Interleaved Interleaved ------------------------------------------------------------------------------------ Special sat. R0.3 A11.0 F2.1 T > C-10.4 0.34 deg 200 mm 200 mm 45 mm None ------------------------------------------------------------------------------------ Geometry Multi-slice mode Series Standard Off Off Off 337.166 V Auto Physio 1st Signal/Mode ------------------------------------------------------------------------------------ Distortion Corr. Prescan Normalize Raw filter Elliptical filter Hamming FIX H 0 mm S - C - T R >> L A >> P F >> H Sum of Squares Default ------------------------------------------------------------------------------------ Contrast MTC Flip angle Fat suppr. PAT mode Matrix Coil Mode Off On On ------------------------------------------------------------------------------------ Off single 9 67 % R0.3 A11.0 F2.1 T > C-10.4 A >> P 0.34 deg 0% 200 mm 100.0 % 3.10 mm 2000 ms 30 ms 1 1 None HEA;HEP Resolution Base resolution Phase resolution Phase partial Fourier Interpolation USER: ep2d_bold_MGH_pro_tb System Body HEP HEA Off Off On Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE Averages Concatenations Filter Coil elements Averaging mode Reconstruction Measurements Delay in TR Multiple series Rel. SNR: 1.00 None 7/+ 0 SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\epi_esp460 TA: 2.0 s PAT: Off Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements Voxel size: 3.1×3.1×3.1 mm Off On Off On Off Off Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Coil Combine Mode Auto Coil Select Off 90 deg Fat sat. ------------------------------------------------------------------------------------ Long term Magnitude 1 0 ms Off 64 100 % Off Off Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H None Auto (CP) BOLD GLM Statistics Dynamic t-maps Starting ignore meas Ignore after transition Model transition states Temp. highpass filter Threshold Paradigm size Meas Motion correction Spatial filter Off Off 0 0 Off Off 4.00 1 Baseline Off Off Sequence Introduction Bandwidth Free echo spacing Echo spacing Off 2520 Hz/Px Off 0.46 ms ------------------------------------------------------------------------------------ EPI factor RF pulse type Gradient mode 64 Normal Fast ------------------------------------------------------------------------------------ Dummy Scans Off Off On Off Off Interleaved Interleaved ------------------------------------------------------------------------------------ Special sat. R0.3 A11.0 F2.1 T > C-12.5 0.34 deg 200 mm 200 mm 45 mm None ------------------------------------------------------------------------------------ Geometry Multi-slice mode Series Standard Off Off Off 337.166 V Auto Physio 1st Signal/Mode ------------------------------------------------------------------------------------ Distortion Corr. Prescan Normalize Raw filter Elliptical filter Hamming FIX H 0 mm S - C - T R >> L A >> P F >> H Sum of Squares Default ------------------------------------------------------------------------------------ Contrast MTC Flip angle Fat suppr. PAT mode Matrix Coil Mode Off On On ------------------------------------------------------------------------------------ Off single 9 67 % R0.3 A11.0 F2.1 T > C-12.5 A >> P 0.34 deg 0% 200 mm 100.0 % 3.10 mm 2000 ms 30 ms 1 1 None HEA;HEP Resolution Base resolution Phase resolution Phase partial Fourier Interpolation USER: ep2d_bold_MGH_pro_tb System Body HEP HEA Off Off On Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE Averages Concatenations Filter Coil elements Averaging mode Reconstruction Measurements Delay in TR Multiple series Rel. SNR: 1.00 None 8/+ 0 SIEMENS MAGNETOM TrioTim syngo MR B15 \\USER\INVESTIGATORS\HST_583\Physics2\epi_esp480_grappa2 TA: 8.0 s PAT: 2 Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements Voxel size: 3.1×3.1×3.1 mm Series Off On Off On Off Off System Body HEP HEA Off On On Positioning mode Table position Table position MSMA Sagittal Coronal Transversal Coil Combine Mode Auto Coil Select FIX H 0 mm S - C - T R >> L A >> P F >> H Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Orientation Rotation R >> L A >> P F >> H Standard Off Off Off 337.166 V Auto R0.3 A11.0 F2.1 T > C-12.5 0.34 deg 200 mm 200 mm 45 mm Physio 1st Signal/Mode None Long term Magnitude 1 0 ms Off BOLD GLM Statistics Dynamic t-maps Starting ignore meas Ignore after transition Model transition states Temp. highpass filter Threshold Paradigm size Meas Motion correction Spatial filter Off Off 0 0 Off Off 4.00 1 Baseline Off Off 64 100 % Off Off Sequence Introduction Bandwidth Free echo spacing Echo spacing Off 2520 Hz/Px Off 0.48 ms ------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------ GRAPPA 2 32 Auto (Triple) Separate ------------------------------------------------------------------------------------ EPI factor RF pulse type Gradient mode 64 Normal Fast ------------------------------------------------------------------------------------ Dummy Scans ------------------------------------------------------------------------------------ Geometry Multi-slice mode None ------------------------------------------------------------------------------------ Off 90 deg Fat sat. Distortion Corr. Prescan Normalize Raw filter Elliptical filter Hamming Interleaved ------------------------------------------------------------------------------------ Off single Contrast MTC Flip angle Fat suppr. PAT mode Accel. factor PE Ref. lines PE Matrix Coil Mode Reference scan mode Special sat. Off Off On 9 67 % R0.3 A11.0 F2.1 T > C-12.5 A >> P 0.34 deg 0% 200 mm 100.0 % 3.10 mm 2000 ms 30 ms 1 1 None HEA;HEP Resolution Base resolution Phase resolution Phase partial Fourier Interpolation USER: ep2d_bold_MGH_pro_tb ------------------------------------------------------------------------------------ Routine Slice group 1 Slices Dist. factor Position Orientation Phase enc. dir. Rotation Phase oversampling FoV read FoV phase Slice thickness TR TE Averages Concatenations Filter Coil elements Averaging mode Reconstruction Measurements Delay in TR Multiple series Rel. SNR: 1.00 Off Off On Off Off Interleaved 9/­ 0