Design Project Part A Solution i. [ ] [ ][ ] [ ] [ ][ ] [ ] [ ][ ] [ ] [ [ ] [ [ ] [ ] ] [ ][ ] [ ] ] [ ] [ ][ ] [ ] [ ][ ] [ ] ii. 1 0.9 0.8 Concentration 0.7 0.6 E S ES EI P I 0.5 0.4 0.3 0.2 0.1 0 0 0.1 0.2 0.3 0.4 0.5 Time 0.6 1 0.7 0.8 0.9 1 iii. Optimal rate parameters: For those of you who are curious, the data was generated using the following rate constants: Clearly, the fitting procedure does a remarkable job of estimating the original rate constants. 1 0.9 0.8 Concentration 0.7 0.6 E S ES EI P I 0.5 0.4 0.3 0.2 0.1 0 0 0.1 0.2 0.3 0.4 0.5 Time 0.6 2 0.7 0.8 0.9 1 MIT OpenCourseWare http://ocw.mit.edu 20.320 Analysis of Biomolecular and Cellular Systems Fall 2012 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.