http://www.dgemap.org/
Jano van Hemert
3 years EU-funded design study
Goal: design the organisational &
collaborative structures, ethical
framework, and molecular genetic &
informatics technologies necessary for a
new research infrastructure which will
accelerate an integrated European
approach to gene expression in early
human development
Jano van Hemert
www.dgemap.org
Consortium
National e-Science Centre
MRC Human Genetics Unit
University of Newcastle
Jano van Hemert
www.dgemap.org
4 work packages
Jano van Hemert
www.dgemap.org
Three major goals
1. Facilitate collaboration over
multiple laboratories
2. Improve ways for handling spatialtemporal data from gene
expression studies
3. Provide integration with other
technologies and databases to
help biologists advance their
studies
Jano van Hemert
www.dgemap.org
Laboratory process
Jano van Hemert
www.dgemap.org
From 2D sections to 3D models
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Jano van Hemert
www.dgemap.org
Framework:
Edinburgh Mouse Atlas
Space and Anatomy
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Jano van Hemert
www.dgemap.org
Space and Anatomy
anatomical name
Jano van Hemert
www.dgemap.org
Gene Expression Database
• Query: by both space and text...
Jano van Hemert
www.dgemap.org
emage: Query by space
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Jano van Hemert
www.dgemap.org
emage: Query by space
Jano van Hemert
www.dgemap.org
Silicon processes
Data mining
Human-mouse link
Visualisation
Jano van Hemert
Other data sources
(OMIM, GDX, …)
www.dgemap.org
The Developing Human e-Portal
Jano van Hemert
www.dgemap.org
Web services exist
Jano van Hemert
www.dgemap.org