Open Access Journals of PJS Group
Photo-induced Pyridine Substitution in cis-[Ru(bpy)2(py)2]Cl2: A Snapshot by Time-resolved
X-ray Solution Scattering
L. Salassa, E. Borfecchia, T. Ruiu, C. Garino, D. Gianolio, R. Gobetto, P.J. Sadler, M.
Cammarata, M. Wulff and C. Lamberti
Inorg. Chem. 2010, 49, 11240-11248.
EXAFS, DFT, light-induced nucleobase binding and cytotoxicity of the photoactive complex
cis-[Ru(bpy)2(CO)Cl]+
L. Salassa, T. Ruiu, C. Garino, A.M. Pizarro, F. Bardelli, D. Gianolio, A. Westendorf, P.J.
Bednarski, C. Lamberti, R. Gobetto, and P.J. Sadler
Organometallics 2010, 29, 6703-6710.
Functionalization of osmium arene anticancer complexes with (poly)arginine: effect on
cellular uptake, internalization and cytotoxicity
S.H. van Rijt, H. Kostrhunova, V. Brabec and P.J. Sadler
Bioconjug. Chem. 2011, 22, 218-226.
Metal Complexes as DNA Intercalators
H. Liu and P.J. Sadler
Acc. Chem. Res. 2011, 44, 349–359.
Organometallic Half-sandwich Iridium Anticancer Complexes
Z, Liu, A. Habtemariam, A. Pizarro, S. Fletcher, A. Kisova, O. Vrana, L. Salassa, P.
Bruijnincx, G. Clarkson, V. Brabec, P.J. Sadler
J. Med. Chem. 2011, 54, 3011-3026.
The Anticancer Drug Cisplatin Can Cross-link the Interdomain Zinc Site on Human Albumin
W. Hu, Q. Luo, K. Wu, X. Li, F. Wang, Y. Chen, X. Ma, J. Wang, J. Liu, S. Xiong, P.J.
Sadler
Chem. Comm. 2011, 47, 6006 - 6008.
[Highlighted: C&E News 89(20) 16 May 2011, p33; Chemistry World 8(6) June 2011, p26]
Differences in the Cellular Response and Signaling Pathways between Cisplatin and
Monodentate Organometallic RuII Antitumor Complexes Containing a Terphenyl Ligand
A. Kisova, Z. Lenka, A. Habtemariam, P.J. Sadler, V. Brabec, J. Kasparkova
Mol. Pharmaceutics 2011, 8, 949-957.
Anti-colorectal Cancer Activity of an Organometallic Osmium Arene Azopyridine Complex
S.D. Shnyder, Y. Fu, A. Habtemariam, S.H. van Rijt, P.A. Cooper, P.M. Loadman, P.J.
Sadler
MedChemComm 2011, 2, 666-668.
Insights into the Acid-Base Properties of PtIV-diazidodiam(m)ine Complexes from
Multinuclear NMR Spectroscopy
L. Ronconi, A.M. Pizarro, R.J. McQuitty, P.J. Sadler
Chem. Eur. J. 2011, 17, 12051-12059.
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Mass spectrometry evidence for cisplatin as a protein cross-linking reagent
H. Li, Huilin, Y. Zhao, H.A. Phillips, Y. Qi, T-Y. Lin, P.J. Sadler, P. O'Connor
Analytical Chem. 2011, 83, 5369–5376.
Contrasting Reactivity and Cancer Cell Cytotoxicity of Isoelectronic Organometallic
Iridium(III) Complexes
Z. Liu, L. Salassa, A. Habtemariam, A.M. Pizarro, G.J. Clarkson, P.J. Sadler
Inorg. Chem. 2011, 50, 5777-5783.
Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex
F. Barragán, P. López-Senín, L. Salassa, S. Betanzos-Lara, A. Habtemariam, V. Moreno, P.J.
Sadler, V. Marchán
J. Am. Chem. Soc. 2011, 133, 14098-14108.
Structure-Activity Relationships for Organometallic Osmium Arene Phenylazopyridine
Complexes with Potent Anticancer Activity
Y. Fu, A. Habtemariam, A.M.B.H. Basri, D. Braddick, G. Clarkson, P.J.Sadler
Dalton Trans. 2011, 40, 10553-10562.
Organometallic Iridium(III) Cyclopentadienyl Anticancer Complexes Containing C,NChelating Ligands
Z. Liu, A. Habtemariam, A.M. Pizarro, G.J. Clarkson, P.J. Sadler
Organometallics 2011, 30, 4702–4710
Reactions of an Organoruthenium Anticancer Complex with 2-Mercaptobenzanilide - a
Model for the Active-site Cysteine of Protein Tyrosine Phosphatase 1B
Y. Han, Q. Luo, X. Hao, X. Li, F. Wang, W. Hu, K. Wu, S. Lü, P.J. Sadler
Dalton Trans. 2011, 40, 11519–11529.
Probing Platinum Azido Complexes by 14N and 15N NMR Spectroscopy
N.J. Farrer, P. Gierth, P.J. Sadler
Chem. Eur. J. 2011, 17, 12059-12066.
DOI: 10.1002/chem.201101409
Use of Top-down and Bottom-up Fourier Transform Ion Cyclotron Resonance Mass
Spectrometry for Mapping Calmodulin Sites modified by Platinum Anticancer Drug
H. Li , T-Y, Lin , S.L. Van Orden , Y. Zhao , M.P. Barrow , A.M. Pizarro , Y. Qi , P.J.
Sadler , and P.B O'Connor
Anal. Chem. 2011, 83, 5369-5376.
Fibrillation of Transferrin
C. Booyjzsen, C. Scarff, B. Moreton, I. Portman, J. Scrivens, G. Costantini, P.J. Sadler
Biochim. Biophys. Acta, 2012, 1820, 427-439.
A molecular mechanism for modulating plasma Zn speciation by fatty acids
J. Lu, A.J. Stewart, D. Sleep, P.J. Sadler, T.J. T. Pinheiro, C.A. Blindauer
J. Am. Chem. Soc. 2012, 134, 1454–1457.
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Ferric ion hydr(oxo) clusters in the ‘Venus-Fly-Trap’ cleft of FbpA: Mössbauer, calorimetric
and mass spectrometric studies
A. Mukherjee, P.R. Bilton, L. Mackay, A. Janoschka, H. Zhu, D. Rea, P.R.R. Langridge-Smith, Dominic J.
Campopiano, Thomas Teschner, Alfred X. Trautwein, Volker Schünemann, Peter J. Sadler
J. Biol. Inorg. Chem. 2012, 17, 573-588.
Photoactivatable Organometallic Pyridyl Ruthenium(II) Arene Complexes
S. Betanzos-Lara, L. Salassa, A. Habtemariam, O. Nováková, A.M. Pizarro, G.J. Clarkson, B.
Liskova, V. Brabec, P.J. Sadler
Organometallics 2012, 31, 3466–3479.
Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium,
rhodium and iridium: biological relevance and synthetic strategies
N.P.E. Barry, P.J. Sadler
Chem. Soc. Rev. 2012, 41, 3264–3279
Interactions of DNA with a New Platinum(IV) Azide Dipyridine Complex Activated by UVA
and Visible Light. Relationship to Toxicity in Tumor Cells
J. Pracharova, L. Zerzankova, J. Stepankova, O. Novakova, N.J. Farrer, P.J. Sadler,
V. Brabec, J. Kasparkova
Chem. Res. Toxicol. 2012, 25, 1099-1111.
Designing organometallic compounds for catalysis and therapy
A.L. Noffke, A. Habtemariam, A.M. Pizarro, P.J. Sadler
Chem. Commun. 2012, 48, 5219-5246.
Combined theoretical and computational study of interstrand DNA guanine-guanine
cross-linking by trans-[Pt(pyridine)2] derived from the photoactivated prodrug
trans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]
H.-C, Tai, R. Brodbeck, J. Kasparkova, N.J. Farrer, V. Brabec, P.J.Sadler, R.J. Deeth
Inorg. Chem. 2012, 51, 6830-6841.
The contrasting Chemical Reactivity of Potent Isoelectronic Iminopyridine and Azopyridine
Osmium(II) Arene Anticancer Complexes
Y. Fu, M.J. Romero, A. Habtemariam, M.E. Snowden, L. Song, G.J. Clarkson, B. Qamar,
A.M. Pizarro, P.R. Unwin, P.J. Sadler
Chem. Sci. 2012, 3, 2485–2494.
Microfluidic integration of photonic crystal fibers for online photochemical reaction analysis
S. Unterkofler, R. McQuitty, T. Euser, N. Farrer, P.J. Sadler, P. Russell
Optics Lett. 2012, 37, 1952-1954.
Bipyrimidine Ruthenium(II) Arene Complexes: Structure, Reactivity and Cytotoxicity
S. Betanzos-Lara, O. Novakova, R.J. Deeth, A.M. Pizarro, G.J. Clarkson, Barbora Liskova, V.
Brabec, P.J. Sadler, A. Habtemariam
J. Biol. Inorg. Chem. 2012, 17, 1033-1051.
Design of Photoactivatable Metallodrugs: Selective and Rapid Light-induced Ligand
Dissociation from Half-Sandwich [Ru([9]aneS3)(N–N')(py)]2+ Complexes
G. Ragazzon, I. Bratsos, E. Alessio, L. Salassa, A. Habtemariam, R.J. McQuitty, G.J.
Clarkson, P.J. Sadler
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Inorg. Chim. Acta 2012, 393, 230-238.
(Bioinorganic Special Issue)
Allosteric Inhibition of Cobalt Binding to Albumin by Fatty Acids: Implications for the
Detection of Myocardial Ischemia
J. Lu, A.J. Stewart, P.J. Sadler, T.J.T. Pinheiro, C.A. Blindauer
J. Med. Chem. 2012, 55, 4425-4430.
Improved Catalytic Activity of Ruthenium-Arene Complexes in the Reduction of NAD+
J.J. Soldevila-Barreda, P.C.A. Bruijnincx, A. Habtemariam, G.J. Clarkson, R.J. Deeth, P.J.
Sadler
Organometallics 2012, 31, 5958-5967.
Resonant X-Ray Emission Spectroscopy Reveals d–d Ligand-Field States Involved in the
Self-Assembly of a Square-Planar Platinum Complex
C. Garino, E. Gallo, N. Smolentsev, P. Glatzel, R. Gobetto, C. Lamberti, P.J. Sadler, L.
Salassa
Phys. Chem. Chem. Phys. 2012, 14, 15278-15281
Somatostatin subtype 2 receptor-targeted metal-based anticancer complexes
F. Barragán, D. Carrion-Salip, I. Gómez-Pinto, A. González-Cantó, P.J. Sadler, R. de Llorens,
V. Moreno, C. González, A. Massaguer, V. Marchán
Bioconjugate Chem. 2012, 23, 1838-1855.
Tryptophan Switch for a Photoactivated Platinum Anticancer Complex
J.S. Butler, J.A. Woods, N.J. Farrer, M.E. Newton, P.J. Sadler
J. Am. Chem. Soc. 2012, 134, 16508-16511.
Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene
anticancer complexes
I. Romero-Canelón, A.M. Pizarro, A. Habtemariam, P.J. Sadler
Metallomics 2012, 4, 1271-1279.
Reduction of Quinones by NADH Catalyzed by Organoiridium Complexes.
Liu, Z.; Deeth, R. J.; Butler, J. S.; Habtemariam, A.; Newton, M. E.; Sadler, P. J. Angew.
Chem., Int. Ed. 2013, 52, 4194-4197.
Photoactivatable metal complexes: from theory to applications in biotechnology and
medicine Nichola A. Smith and Peter J. Sadler. Phil. Trans. R. Soc. A. 2013, DOI:
10.1098/rsta.2012.0519
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