Non-coding RNA, Epigenetic Memory, and the Environment Conference April 14-15, 2011 London, UK Organisers: Eric Miska and Abcam PROGRAMME April 14, 2011 09.00 – 09.50 09.50 – 10.00 10:00 – 10:35 10:35 – 11:10 11:10 – 11:40 11:40 – 11:50 11:50 – 12:10 12:10 – 12:30 12:30 – 12:50 12:50 – 13:50 13:50 – 14:10 14:10 – 14:45 14:45 – 15:05 15:05 – 15:35 15:35 – 16:10 16:10 – 16:45 16:45 – 18:45 Registration Welcome and Introductions Session 1 David Baulcombe (University of Cambridge, UK) RNA silencing and epigenetic memory in plants Craig Hunter (Harvard University, US) Biogenesis, transport, and function of extracellular RNA in C. elegans Coffee break Abarna Thiru, Business Development Manager A few words from Abcam Erica Gerace The Methyltransferase Activity of Clr4/Suv39h Triggers RNAi independently of Histone H3K9 Methylation Julie Ahringer Chromatin regulation in transcription and splicing Susannah Varmuza Recent acquisition of imprinted regulation in the rodent PcG gene Sfmbt2 by insertion of miRNA Lunch Session 2 Boyan Bonev microRNA-9 promotes regional diversity during vertebrate neural development Eric Miska (University of Cambridge, UK) Transgenerational epigenetic inheritance in C. elegans Antony Jose Two classes of silencing RNAs move between C. elegans tissues Tea/coffee break Alexei Aravin (Caltech, US) Small RNA pathways in germline Kazufumi Mochizuki (IMBA Vienna, Austria) RNA-directed elimination in tetrahymena Poster session and drinks reception April 15, 2011 09.00 – 09.40 09.40 – 10.00 10.00 – 10.20 10:20 – 10:40 10:40 – 11:00 11:00 – 11:30 11:30 – 12:05 12:05 – 12:25 12:25 – 13:00 13:00 – 14:00 14:00 – 14:20 14:20 – 14.55 14:55 – 15:15 15:15 – 15:50 15:50 – 16:25 16:25 – 16:35 16:35 Session 3 Emma Whitelaw (Queensland Institute for Medical Research, Australia) An ENU screen for modifiers of epigenetic reprogramming Alyson Ashe Inheritance of transgenerational silencing in C. elegans is associated with the presence of small RNAs Angelique Deleris Transgenerational genome-wide analyses of ibm1 and met1 mutants provide insights into the control and amplification of H3K9m2 deposition in Arabidopsis thaliana Jie Song A Polycomb-based switch underlying quantitative epigenetic memory Helen Rowe KAP1/TRIM28-induced de novo DNA methylation of IAPs: implications for epigenetic inheritance Coffee break Bill Kelly (Emory University, US) Transgenerational regulation of the germline epigenome in C. elegans Keijo Viiri The Polycomb protein Suz12 is an RNA binding protein Kevin Morris (The Scripps Research Institute, US) Non-coding RNAs; epigenetic regulators of gene transcription in human cells Lunch Session 4 Victoria Green Promoter architectures susceptible to small RNA-induced transcriptional gene silencing John Rinn (Harvard/MIT, US) Some missing LincRNAs in cellular differentiation Juan Pablo Couso Small open reading frames in putative long non-coding RNAs: hidden, abundant, functional Wolf Reik (Babraham Institute, UK) Epigenetic reprogramming in mammalian development Olivier Voinnet (University of Strasbourg, France) tbc Closing remarks Conference ends Last updated 16 March 2011