UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Table of Contents
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
1.
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
Chemical Product
Product Name: Sodium Citrate
Chemical name: Trisodium salt of 2-hydroxypropane-1,2,3,tricarboxylate
Synonyms: Sodium citrate dihydrate; Citric acid trisodium salt dihydrate; Sodium citrate
tribasic dihydrate; Trisodium citrate dihydrate; Citrosodine; 2-hydroxy-1,2,3propanetricarboxylic acid trisodium salt dihydrate
Chemical Formula:
Na3C6H5O7 · 2H2O
2.
Composition and Information on Ingredients
Composition:
100% sodium citrate
Sodium ion content typically 23 - 24%
Toxicological Data on Ingredients: Not applicable
3.
Hazards Identification
Potential Acute Health Effects: Irritation on contact with skin and eyes, or if ingested or
inhaled.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not applicable
MUTAGENIC EFFECTS: Not applicable
TERATOGENIC EFFECTS: Not applicable
DEVELOPMENTAL TOXICITY: Not applicable
4.
First Aid Measures
General measures:
Skin contact: Flush excess material off. Wash skin with soap and water. If irritation persists
seek medical attention.
Serious skin contact: Not applicable
Page 2 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
Eye contact: Flush with large amounts of cool running water for at least 15 minutes. Seek
medical attention as necessary.
Ingestion: Have patient drink several glasses of water. Get medical attention if large doses
were consumed.
Serious ingestion: Not applicable
Inhalation: For excessive inhalation remove to fresh air. If breathing is difficult seek
medical attention.
Serious inhalation: Not applicable
5.
Fire and Explosion Data
Flammability of the Product: Not applicable
Auto-Ignition Temperature: Not applicable
Flash points: Not applicable
Flammable limits: Not applicable
Products of Combustion: Hazardous decomposition products formed under fire conditions Carbon oxides
Fire Hazards in Presence of Various Substances: Not Applicable
Explosion Hazards in Presence of Various Substances: Not Applicable
Fire fighting media and Instructions: Use water spray, alcohol-resistant foam, dry
chemical or carbon dioxide. Wear self contained breathing apparatus for fire fighting if
necessary.
Special Remarks on Fire Hazards: Not applicable
Special Remarks on Explosion Hazards: Dust dispersed in air in sufficient concentrations,
and the presence of an ignition source is a potential dust explosion hazard.
Page 3 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
6.
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Spills: Clean up spills in a manner that does not disperse dust into the air by moistening with
water. Use non-sparking tools and equipment.
7.
Handling and Storage
Precautions: Keep away from heat, sources of ignition and any incompatibles such as
oxidising agents.
Storage: Store in tightly closed containers, in a cool, dry, well ventilated area, and away from
humidity (maximum 25°C and 50% relative humidity).
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Applicable
Engineering Controls: Not Applicable
Personal Protection: Avoid breathing dust by wearing an approved appropriate mask, avoid
contact with eyes by wearing safety glasses, and wear appropriate gloves to avoid skin
contact.
9.
Physical and Chemical Properties
Physical state and appearance: White granular solid
Odour: Not applicable
Taste: Not applicable
Molecular Weight: 258 – 294g
pH (5% solution/water): 7 - 9
Boiling Point: Decomposes at red heat
Melting Point: 150°C
Critical Temperature: Not Applicable
Specific Gravity (Water = 1): 1.97 920-1150 kg/m3
Vapour Pressure (mmHg): Not Applicable
Vapour Density: Not applicable
Page 4 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
Volatility: Not applicable
Odour Threshold: Not applicable
Water/Oil Distribution Coefficient: Not Applicable
Ionicity (in Water): Not Applicable
Dispersion Properties: Not Applicable
Solubility: 40 - 60% w/w
10.
Stability and Reactivity Data
Stability: Stable under ordinary conditions of use and storage; 25°C maximum and 50%
relative humidity. It deliquesces in moist air.
Corrosivity: Not applicable
Instability temperature: Not applicable
Conditions of Instability: Heat, flame, ignition sources, dusting and incompatibles.
Incompatibles: Strong oxidisers
Polymerization: Not applicable
11.
Toxicological Information
Toxicity to animals: Not applicable
Effects on humans:
Acute potential health effects: Irritation on contact with skin and eyes, or if ingested or
inhaled.
Chronic potential health effects:
MUTAGENIC EFFECTS: Not applicable
TERATOGENIC EFFECTS: Not applicable
DEVELOPMENTAL TOXICITY: Not applicable
Other information: Not Applicable
Page 5 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval
12.
Ecological Information
Ecotoxicity: Not applicable
13.
Disposal Considerations
Waste Disposal: What is not recycled must be handled as hazardous waste and sent to an
approved incinerator or disposed in an approved waste facility. Dissolve in water and dispose
with non-hazardous waste.
14.
References
- ADM. Material Safety Data Sheet; Sodium Citrate. [online]. 2009 [cited 2013 Nov 6].
Available
from:
URL:
http://www.adm.com/enUS/worldwide/australia/Documents/Sodium%20Citrate%20AU.pdf
-
Colonial Chemical Solutions, Inc. Material Safety Data Sheet; Sodium Citrate. [online].
2008
[cited
2013
Nov
6].
Available
from:
URL:
http://colonialchemicals.com/uploads/Products/Sodium%20Citrate/Sodium%20Citrate_
MSDS.pdf
-
Material Safety Data Sheet. [online]. 2011 [cited 2013 Nov 6]. Available from: URL:
http://proscitech.com.au/cataloguex/msds/c077.pdf
-
Material Safety Data Sheet; Sodium Citrate. [online]. 1996 [cited 2013 Nov 6].
Available from: URL: http://www.ce.siue.edu/safety/MSDS/107.pdf
15.
Appendices
Not applicable
16.
Revision History
Version Number
Amendments/ Reasons for change
01
Initial Release
Page 6 of 7
UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
SODIUM CITRATE
Page 7 of 7
Ref. No.
MSDS /PD/35_01
Valid for:
2 years from approval