UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
POTASSIUM DIHYDROGEN PHOSPHATE
Table of Contents
Valid for:
2 years from approval
Page
1. Chemical Product
2. Composition and Information on Ingredients
3. Hazards Identification
4. First Aid Measures
5. Fire and Explosion Data
6. Accidental Release Measures
7. Handling and Storage
8. Exposure Controls/ Personal Protection
9. Physical and Chemical Properties
10. Stability and Reactivity Data
11. Toxicological Information
12. Ecological Information
13. Disposal Considerations
14. References
15. Appendices
16. Revision History
Page 1 of 9 Ref. No.
MSDS /PD/7_01
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UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Chemical Product
1.
Product Name: Potassium dihydrogen phosphate
Chemical name: Potassium dihydrogen phosphate
Synonyms: Monopotassium phosphate, potassium dihydrogen phosphate, phosphoric acid,
monopotassium salt
Chemical Formula: KH2O4
2.
Composition and Information on Ingredients
Composition: Potassium phosphate monobasic 100% by weight
Toxicological Data on Ingredients: N/A
3.
Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin contact (irritant), eye contact
(irritant), ingestion and inhalation, and slightly hazardous in case of skin contact (permeator).
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: N/A
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: N/A
DEVELOPMENTAL TOXICITY: N/A. Repeated or prolonged exposure is not known to aggravate
medical condition.
Page 2 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
4.
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
First Aid Measures
General measures: N/A
Skin contact: In case of contact, immediately flush skin with plenty of water and cover the
irritated skin with an emollient. Remove any contaminated clothing and shoes, and wash
clothing with cold water, and thoroughly clean shoes before reuse. Seek medical attention.
Serious skin contact: Wash with a disinfectant soap and cover the contaminated skin with an
anti-bacterial cream. Seek medical attention.
Eye contact: Check for and remove any contact lenses. In case of contact, immediately flush
eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical
attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel, and never
give anything by mouth to an unconscious person. If large quantities of this material are
swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or
waistband.
Serious indigestion: N/A
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Seek medical attention.
Serious inhalation: N/A
Page 3 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
5.
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Fire and Explosion Data
Flammability of the Product: Non flammable.
Auto-Ignition Temperature: Not applicable.
Flash points: Not applicable.
Flammable limits: Not applicable.
Products of Combustion: N/A
Fire Hazards in Presence of Various Substances: Not applicable. Explosion Hazards in Presence of Various Substances:
- Risks of explosion of the product in presence of mechanical impact: N/A
- Risks of explosion of the product in presence of static discharge: N/A
Fire fighting media and Instructions: Not applicable.
Special Remarks on Fire Hazards: N/A
Special Remarks on Explosion Hazards: N/A
Page 4 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
6.
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Accidental Release Measures
NB: Wear appropriate protective equipment/clothing including gloves before removing
any spills.
Small spill: Use appropriate tools to place the spilled solid in a convenient waste disposal
container. Finish cleaning by spreading water on the contaminated surface and dispose of the
material according to local and regional authority requirements.
Large spill: Use a shovel to put the material into a convenient waste disposal container. Finish
cleaning by spreading water on the contaminated surface and allow the mixture to evacuate
through the sanitary system.
7.
Handling and Storage
Precautions: Do not ingest or breathe in dust, and wear suitable protective clothing. In case of
insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice
immediately and show the container or the label. Avoid contact with skin and eyes and keep
away from incompatibles such as alkalis.
Storage: Keep container tightly closed and store in a cool, well-ventilated area.
Page 5 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: N/A
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering
controls to keep airborne levels below recommended exposure limits. If user operations
generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below
the exposure limit.
Personal Protection: Splash goggles, lab coat, dust respirator, making sure to use an
approved/certified respirator or equivalent, and gloves.
9.
Physical and Chemical Properties
Physical state and appearance: White solid (Crystalline solid. Granular powder solid).
Odour: Odourless
Taste: N/A
Molecular Weight: 136.09 g/mole
pH (1% solution/water): 4.5 [Acidic.] in a 5% soln/water
Boiling Point: N/A
Melting Point: 253°C (487.4°F)
Critical Temperature: N/A
Specific Gravity (Water = 1): 2.34
Vapour Pressure (mmHg): Not applicable.
Vapour Density: N/A
Volatility: N/A
Odour Threshold: N/A
Water/Oil Distribution Coefficient: N/A
Ionicity (in Water): N/A
Dispersion Properties: See solubility in water.
Solubility: Soluble in cold water and insoluble in alcohol.
Page 6 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Stability and Reactivity Data
10.
Stability: The product is stable.
Corrosivity: Non-corrosive in presence of glass.
Instability temperature: N/A
Conditions of Instability: Incompatible materials.
Incompatibles: Non-corrosive in presence of glass.
Polymerization: Will not occur.
11.
Toxicological Information
Toxicity to animals: Acute dermal toxicity (LD50): >4640 mg/kg [Rabbit].
Effects on humans:
Acute potential health effects:
- Skin: May cause skin irritation. Risk of skin absorption is slight.
- Eye: Dust may cause eye irritation.
- Inhalation: Inhalation may cause respiratory tract irritation, coughing and choking.
- Ingestion: Ingestion of large amounts may cause nausea, vomiting, abdominal
discomfort (cramps) and diarrhoea. Also, symptoms of potassium poisoning may
occur, which may include slow heartbeat, peripheral vascular collapse with fall in
blood pressure, cardiac arrhythmias, heart block, accelerated breathing, and muscle
weakness, heaviness of the legs, flaccid paralysis, cold skin and gray pallor. May affect
behaviour (listlessness, mental confusion).
Chronic potential health effects: Dermatitis may develop from repeated or prolonged skin
contact.
MUTAGENIC EFFECTS: N/A
TERATOGENIC EFFECTS: N/A
DEVELOPMENTAL TOXICITY: N/A
Other information: Hazardous in case of skin contact (irritant), ingestion and inhalation, and
slightly hazardous in case of skin contact (permeator).
Page 7 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
12.
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Ecological Information
Ecotoxicity: N/A 13.
Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with local environmental control
regulations.
14.
References
-
Sciencelab.com. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online].
2005
[cited
2012
Oct
10].
Available
from:
URL:
http://www.sciencelab.com/msds.php?msdsId=9927235
-
Bakerbro.com. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online].
2006 [cited 2012 Oct 10]. Available from: URL:
http://www.bakerbro.com/pdf_library/Fertilizer/Innophos_Monopotassium_Phosphate_An
hydrous_MSDS.pdf
-
Cen.iitb.ac.in. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online]. 2010
[cited 2012 Oct 10]. Available from: URL:
http://www.cen.iitb.ac.in/cen/new%20msds/KH2PO4.pdf
-
Westliberty.edu. Material Safety Data Sheet; Potassium dihydrogen phosphate [Online].
2012 [cited 2012 Oct 10]. Available from: URL: http://www.westliberty.edu/health-andsafety/files/2012/08/potassium-dihydrogen-phosphate.pdf
Page 8 of 9 UNIVERSITY OF MALTA
FACULTY OF MEDICINE & SURGERY
PHARMACY DEPARTMENT
MATERIAL SAFETY
DATA SHEET
15.
POTASSIUM DIHYDROGEN PHOSPHATE
Ref. No.
MSDS /PD/7_01
Valid for:
2 years from approval
Appendices
N/A 16.
Revision History
Version Number Amendments/ Reasons for change
01
Initial Release
Page 9 of 9