College of Arts and Sciences American University Washington, D. C. Spring 2006 www.american.edu/cas AMERICAN UNIVERSITY SCIENCE EDITORIAL Mission Statement: SCIENCE ISSUES—You decide: Hurricanes and Global Warming In addition to the loss of life and property, last season’s hurricanes have brought renewed scrutiny of global warming. Most scientists maintain that global warming exists, but some are still unsure about what links there are, if any, between global warming and the increased force of hurricanes. A catalyst, as defined by scientists, facilitates chemical reactions by bringing together substances that might not interact in its absence. Similarly, Catalyst is one place where all the sciences come together to relay exciting scientific developments happening at AU in the AU community and beyond. According to the National Hurricane Center, a hurricane is “a non-frontal synoptic scale lowpressure system over tropical or sub-tropical waters with organized convection (i.e., thunderstorm activity) and definite cyclonic surface wind circulation.” Catalyst is a semi-annual magazine created to Scientists say that three conditions are necessary for a hurricane to take place: mission is to: serve students and faculty in the • continuing evaporation-condensation cycle of warm, humid ocean air sciences as a means to inspire, inform, and promote • patterns of wind characterized by converging winds at the surface and strong, uniform-speed winds at higher altitudes promote discourse and keep us up-to-date about how science at AU affects and inspires us all. Our discourse; share news and accomplishments of students and faculty; inform students of timely and valuable opportunities; raise the profile of the • a difference in air pressure (pressure gradient) between the surface and high altitude sciences at AU; and expose students outside of CAS Several recent studies have examined ocean temperatures and their role in the increased intensity of hurricanes. For example, a study conducted by Kevin Trenberth of the National Center for Atmospheric Research links stronger hurricanes to warmer seas and global warming caused by human beings. Trenberth also contends that global warming has raised sea levels and ocean temperatures. This has increased water vapor in the atmosphere and brought about storms, he said. to exciting science classes. Our success will be measured by how useful and informative you find this publication, so we want to hear from you! Editor: Mishri Someshwar Likewise, researchers at the Georgia Institute of Technology found that the number of Category Four and Five hurricanes worldwide has nearly doubled over the past 35 years, even though the total number of hurricanes has dropped since the 1990s. These researchers say that sea temperatures have risen by 0.5 to 1 degree Fahrenheit. But the link between human-induced global warming and more intense hurricanes is still unclear. ms1044a@american.edu Other scientists, however, dismiss the link between global warming and hurricane intensity and say the present hurricane surge is part of a 60- to 70-year cycle linked to natural causes. They say climate change due to human activity will not significantly affect hurricanes. Michael Menachem Faculty Advisor: Christopher Tudge ctudge@american.edu Senior Writer: So, is there a link between hurricanes and global warming? a) Definite link between hurricanes and global warming b) Possible link between hurricanes and global warming c) No link between hurricanes and global warming d) Insufficient data e) Global warming does not exist Catalyst is published semi-annually by the Please submit letters to the editor to ms1044a@american.edu. See letters to the editor on the inside back cover. College of Arts and Sciences American University, 4400 Massachusetts Avenue, NW Washington, DC. 20016 Catalyst is supported in part through generous donations from alumni and friends of the College of Arts and Sciences. www.american.edu/cas/catalyst If you wish to make a donation online, go to giving.american.edu/gift. Under Areas of Benefit, choose College of Arts and Sciences, then fill in the amount of your donation. At the Designation/In honor of window, key in: Catalyst magazine. Thank you. ON THE COVER Inspired by the film Scarface, the cover features AU psychology and premedical student Nilesh Tejura. Photo by Jeff Watts. I just received the latest issue of Catalyst. It’s an enjoyable magazine. Keep it up. Although your summary of the [intelligent design] controversy is wonderfully stated, it seems to me the final question missed the point. I might suggest that it’s not whether the two topics should be taught in school, but where. Creationism belongs in religion classes while evolution belongs in science. If creationism is taught at all it might be used as an example of its failure to meet the basic requirement of scientific examination. Regards, Ben Van Dyk CAP ’66 I think your question “What views on human origin do you feel should be taught in school?” is too vague. “What views on human origin do you feel should be taught in science class?” would be better. Then one could say that there is no place for a religion/creationism/intelligent design theory. This issue could have affected the curriculum here in Mississippi. Last year a bill was proposed to give equal time in our public school science classes to intelligent design. Thankfully, it did not go very far. Jim Dunne CAP ’95 (PhD) T esting the evolutionary hypothesis may involve taking samples. Thus, caution should be considered when “leaping to a conclusion” about its truthfulness, whether or not on all fours. In statistical hypothesis testing, for example, sample evidence either tends to support the null hypothesis or tends not to. What may be necessary (but not necessarily sufficient) to verify the truth or falsehood of a null hypothesis is to conduct a census with no error, although such a census may be impossible. For example, testing the hypothesis “There is an omnipresent God that created everything” may be outside the realm of scientific research: where’s the control? As asserted, at times, in qualitative research paradigm(s), science is a subset of research, not necessarily the other way round. Any hypothesis verification is subject to research constraints and assumptions. Constraints constrain and assumptions assume. Thus, hypothesis testing may be subject to error. I don’t know if evolution is true: I’ve never seen it. (I’ve never seen a purple cow, either.) Nevertheless, I believe everyone should continue to think more and more “outside the box.” We have a responsibility to better expose students to various research doctrines, scientific and otherwise. By doing so, perhaps their thinking “abilities” might evolve from, for example— believing that evolution is true because there are scientists who conclude it is, or believing that evolution is not true because there are people who don’t believe it—to, for example—comparing various points of view, synthesizing available information and beliefs, and forming conclusions. Is the glass half-empty or half-full? Who knows? But let us drink together. Whiting J. Wicker Math ’02 (PhD) SIGN UP FOR MONTHLY E-MAILS TO FIND OUT ABOUT CAS EVENTS AT AU. To sign up, send an e-mail to cas-mail@american.edu with the subject line: CAS EVENTS-Subscribe. SCIENCE ISSUES—YOU DECIDE: HURRICANES AND GLOBAL WARMING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Inside front cover SCIENCE STARS: Student Projects Affecting You! AU Student Participates in Hurricane Katrina Relief Effort . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Environmental science student Cary Shelton interns with Red Cross Profile: Psi Chi president Kimberly Bowen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Psychology student helps re-launch AU chapter of a psychology honors society Power Convergence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Math student Sarah Gourlie studies the convergence of complex power series The Genetics of Alcohol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Psychology student Pete Roma and chemistry student Jonathan Edwardsen research blood alcohol Black Holes, Photos, and NASA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Physics student Johanna Teske interns at NASA Saving the Big Cats . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Biology student Courtney Elkins participates in the National Zoo’s feline conservation program Annihilating Alien Species. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Environmental science student Lea Bonfiglio destroys invasive plant species The Virus Hunter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 Computer science student Erik Hochweller tracks the spread of computer viruses GETTING OUT OF DODGE: Students Take Science Out of D.C. Area . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 In a Country Far, Far Away Psychology and premedical student Nilesh Tejura volunteers in Indian hospitals PROFESSOR PROFILES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 James Girard: Chemistry professor testifies in lead poisoning case in Rhode Island Nancy Zeller and Karen Bushaw-Newton: Biology professors conduct cosmetics study WHERE ARE THEY NOW? Tracking Down Science Alumni . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 PIPING HOT: Scholarships, Internships, and Jobs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11 LETTERS: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Inside back cover Taking Science Out of D.C. Cary Shelton at the Red Cross building in Washington, D.C., wearing the traditional Red Cross vest. Photo by Alanna Bornstein. AU STUDENT PARTICIPATES IN HURRICANE KATRINA RELIEF EFFORT By Claire Maude, journalism ’08 THERE ARE MORE THAN 1,000 MILES BETWEEN Washington, D.C., and New Orleans. But that isn’t stopping Cary Shelton (ENVS ’06) from using her AU education to help in the Katrina relief effort. Shelton is a student in the new AU professional science master’s program, where she studies environmental science and assessment, and interns as a member of the Red Cross’s Disaster Services Team. “I’m doing mostly case work right now since I came in during Katrina,” Shelton said. “Basically, I sit down with an evacuee and write up a case . . . just basically listening to them—most of these people just need to talk to someone, and we provide that as well as helping them find shelter and health care and giving them some monetary assistance.” After the Katrina relief efforts slow down, Shelton says her work will focus more on other types of environmental crises. “[I] will be doing some disaster assessment in regard to fires,” Shelton said. “I hope to be able to do some more extensive training in the future to become a Disaster Action Team (DAT) member. I’m doing the internship for the entire semester and will probably stay on as a DAT member if I remain in the area.” The professional science master’s degree program (www.american.edu/psm) was introduced last year at AU. Throughout the twoyear course of study, Shelton will take 36 credit hours of classes, finish an internship, and work toward a capstone project on a practical problem in the field of environmental science. “The curriculum blends the scientific aspect and the business or policy aspect of the environmental field,” Shelton said. “The program is in its first years, and we were the first ones to come through. The people are Catalyst Spring 2006 2 great, they are helpful, and they have tried really hard to get us through a sudden and tough transition without any hassles.” In the program, Shelton has taken classes in everything from statistics to ethics. She is working with an advisor who will guide her through the process of completing the internship and her final internship report. That project could be anything from a research paper about her work with the Red Cross to a grant proposal or a newspaper article about the organization. After she graduates, Shelton hopes to work in the field of water quality assessment— though she says she doesn’t want to limit herself to that one area. “I may decide I really enjoy damage assessment and decide to pursue a career in that. I’m hoping to be able to leave this program with a sense of not just the scientific side but also some policy and business knowledge as well,” Shelton said. PROFILE: PSI CHI PRESIDENT KIMBERLY BOWEN By Michael Menachem, public communication ’04 KIMBERLY BOWEN (PSYC ’07) HELPED re-launch the AU chapter of the psychology honors society Psi Chi in spring 2005. Bowen, the chapter’s president, says that the organization is “a strong résumé builder and a great resource for getting references for jobs. Psi Chi gives $250,000 in grants each year for student research, and each member receives quarterly research journals,” she said. Bowen, who is originally from Santa Barbara, California, is also president of the Psychology Students Association, a student organization that overlaps with Psi Chi members and activities. She hopes to earn a PhD in clinical psychology and start her own practice. Her interest in psychology grew when working with her high school speech therapist’s autistic son. Learning disabilities, behavioral disorders, and counseling for families and children have always interested Bowen, so her special education minor seemed a logical fit. Bowen is doing her honors capstone project with Professor Bryan Fantie. Her yearlong independent study is on an aspect of evolutionary theory called the parental investment theory. This explains differences in mate selection and the ways in which humans and animals select their mate to produce the fittest offspring. “Females are looking for males who can provide for their offspring; they are looking for resourcefulness. Males are looking for females who can reproduce successfully and have healthy offspring,” Bowen said. Bowen emphasized that students who get involved outside the classroom and are members of Psi Chi have a number of advantages over other students. “The Psi Chi Journal of Undergraduate Research is great because it’s tough to be an undergraduate and get published otherwise,” she said. Psi Chi’s members must meet competitive eligibility requirements. Students must be at least second-semester sophomores maintaining at least a 3.0 cumulative GPA, in the top 35 percent of their class ranking, and have nine completed credits in psychology. Members pay a lifetime membership fee of $35. Bowen said that AU’s chapter conducts practice sessions and tests for the Graduate Record Examinations, and it works with the psychology department to organize graduate resource sessions. During its movie nights members discuss how psychology is reflected in popular culture and how issues in films apply to current findings and general misconceptions in public knowledge. Psi Chi is also working with Active Minds, AU’s mental health awareness organization, to cosponsor major speakers to address students, she said. Bowen urges psychology students to get involved on campus. “Even if people don’t know if they can qualify for Psi Chi, they can still get involved with the Psychology Students Association,” she said. For more information about Psi Chi, visit www.psichi.org. POWER CONVERGENCE By April Astor, journalism ’06 MANY PEOPLE WANT THEIR WORK TO BRING them power. SARAH GOURLIE (MATH ’06) isn’t any different. Over the summer of 2004, she studied the convergence of complex power series with Professor Dan Kalman. A power series is a series such as 1 + x + x2 + x3 + . . ., where you plug in a number for x. But it gets harder. The x’s Gourlie used in this formula were complex numbers. That means they have a real part, like an integer, and an imaginary part, like the “number” i (the square root of -1). So instead of x, she could use a number like 1+2i and study the effect that had on the power series. The series above has many variations depending on the complex number used. Gourlie looked at what happened when those power series were graphed in an unusual way. The graphs are geometric shapes where each term of the series corresponds to a line segment in the graph. Gourlie studied the convergence of the series using their graphs: convergent series give a path of segments that gets smaller and smaller and leads to a single point, whereas divergent series give paths that go to infinity. Catalyst Spring 2006 3 What is not well known, Gourlie said, is the variety of the pictures she was able to generate. “They’re all totally different and they all come from the same equation,” she said. “It’s not the convergence itself that is unusual so much as how they converge and what the graph looks like as the function is converging.” It is an interesting way to study the properties of functions, she said. Gourlie is continuing the research this semester as an honors capstone project. She is now considering variations on her earlier work by studying the effects of what she did and looking at their graphs. She is taking variations of the power series by changing the coefficients and looking at their convergence graphs. For example, where the earlier work focused on 1 + x + x2 + x3, etc. , her more recent work concerns sums like 1x + 2x2 + 3x3, etc. “I’m using more and more complex functions to put x’s into,” she said. Gourlie chose this type of research because it helps her be original within mathematics, which can sometimes be a struggle. “It’s a hump you have to get over between calculus and proof-based math,” she said. “There’s an originality hump and I think this research really helped me with that.” Gourlie plans to write a paper on her work. She has already presented some of her material at the Regional Conference of the Mathematical Association of America. She plans to continue to graduate school and hopes to become an acoustical engineer. A graphical representation of an infinite series in the complex plane Chemistry and psychology double major Jonathan Edwardsen injects a Psychology student Pete Roma ponders the genetic basis standard solution into the gas chromatograph to assure the accurate of alcohol abuse. Photo by Jason Baustin. calibration of the instrument. Photo by Mary-Kate McKenna. THE GENETICS OF ALCOHOL By Michael Menachem, public communication ’04 ACCORDING TO THE NATIONAL INSTITUTE ON Alcohol Abuse and Alcoholism (NIAAA), nearly 18 million American adults abuse alcohol or are alcohol-dependent, with millions more recreational and underage abusers. The estimated cost of alcohol-related problems in America is $185 billion per year. These problems intrigue scientists and are being investigated further on campus. Using selected rat strains, AU’s psychology and chemistry departments have recently conducted an interdisciplinary study on the genetics of alcohol’s effects. These rat strains (“Fischer” and “Lewis”) differ in their willingness to self-administer a variety of drugs. In a number of experiments, psychology professor Anthony Riley and graduate student Pete Roma (PSYC ’07) analyzed the behavioral reactions to alcohol in the two strains. Their data suggest that there are clear differences in the psychological reactions that different strains of rats had to alcohol. Roma said that abused drugs, such as alcohol, have several physiological and psychoactive effects that can be both rewarding and aversive for the user. Roma described these reactions further: “An important factor in the etiology of drug abuse is how rewarding or aversive an individual’s initial experiences with a drug are. If a drug is perceived as highly rewarding and minimally aversive, then subsequent use and abuse potential is high; conversely, if a drug is perceived as highly aversive and minimally rewarding, then abuse potential is low.” Given that the likelihood of continuing drug use is a function of the balance between these two effects, these scientists are interested in why the strains differ and whether this information illuminates the genetic basis of drug use and abuse. One obvious difference between the strains may be how they metabolize alcohol. To assess this, Riley and Roma needed to measure the blood alcohol levels. This is where the chemistry department entered the story. Professor James Girard and undergraduate JONATHAN EDWARDSEN (CHEM/PSYC ’07) used a variety of chemical assays to measure trace levels of chemicals (and drugs) in the body. Gas chromatography was used to determine these levels. In this procedure, after blood is injected into the gas chromatograph, a Catalyst Spring 2006 4 pre-column separates blood components from any alcohol that might be present. Different substances emerged from the gas chromatograph’s column at different retention times, separating different types of compounds. “The more volatile the compound, the faster it comes out of the column,” Edwardsen said. “Ethanol, methanol, propanol, and other compounds all come out at different times due to their vapor pressure.” Using this technique, chemists can determine the absolute concentration of alcohol in the blood of the two rat strains, allowing the psychologists to ascertain whether differences between the strains simply reflect these different blood alcohol levels. The psychologists have administered fixed doses of alcohol to both Fischer and Lewis rats and recorded blood alcohol levels at different times post injection— 15, 60, and finally, 180 minutes. Roma works with Professor Anthony Riley in the psychopharmacology laboratory, where the primary research focus is on animal models of genetic and environmental factors in the etiology of drug use and abuse. He is part of a PhD program called behavior, cognition, and neuroscience. Roma earned a dual BA in psychology and communication studies at West Chester University in Pennsylvania before his research training fellowship at the National Institutes of Health, where he studied biobehavioral development in nonhuman primates. Edwardsen hopes to do advanced analytical chemistry research or forensic chemistry for the FBI, the Secret Service, or another government agency. He has experience as an emergency medical technician and has observed a variety of people at different levels of intoxication; such experiences have provided him with a keen appreciation for how drugs affect people in everyday life. Roma said the interdepartmental collaboration is important because “the longterm goal of our [psychology department] partnership with the chemistry department is to strengthen our behavioral research by including biochemical data, such as circulating levels of drugs or stress hormones, and seeing how those data correlate with the behavioral effects we observe. This partnership also provides chemistry students opportunities to expand their technical repertoires into the realm of biobehavioral research.” BLACK HOLES, PHOTONS, AND NASA By Rebekah Moan, journalism ’06 ALTHOUGH BLACK HOLES ARE REGIONS OF space-time from which nothing can escape, not even light, what we know about them could change in the near future. JOHANNA TESKE (CAP ’08), who is interning at the National Aeronautics and Space Administration’s Goddard Space Flight Center, is working on just that. Teske, who is at Goddard through the D.C. Space Grant Consortium’s Academic Internship with NASA, said her mentor, Demos Kazanas, is “trying to describe a theory of black holes that doesn’t end in a singularity.” A singularity occurs when the laws of physics break down. In a black hole, she said, matter has infinite volume yet is infinitely small, and space-time folds in on itself. “Currently, the theory of black holes is kind of stuck since a singularity is reached and all the equations that could be used outside a black hole break down,” Teske said. She went on to confirm that a total information loss occurs. Teske said the research she is assisting in is important because “if we can help describe nonsingular black holes, then the whole idea of a black hole could change. Right now we know Catalyst Spring 2006 5 light and everything else goes into it and never escapes, but what happens to it?” So far Teske has mostly conducted background research to prepare for the nonsingularity research. She and another intern have mostly been brushing up on their classical mechanics and trying to figure out the Mathematica software so they can plot photon orbits in black holes. Teske said the most rewarding part of interning at Goddard so far has been figuring out how to “plot the orbit of a particle coming toward a black hole, but then getting shot out again.” By using the Mathematica software she can animate the equation and “see” it happen. “In the upcoming weeks we’re going to start digging into the real research aspect of the project, where the equations get messy and we don’t know what will happen,” she said The outcome of the research will bring scientists one step closer to understanding how black holes work and affect our universe and will help create a more elegant theory of black holes. Teske is very excited about this unique internship opportunity. “I actually pulled a jaw muscle from screaming when I found out I'd gotten the internship,” she said. “In my opinion, you really can't get an internship better than this one. What could top exploring the mysteries of our universe and getting paid for it?” SAVING THE BIG CATS ANNIHILATING ALIEN SPECIES By Natasha Malhotra, biology ’09 Kelly Chernin, journalism ’07 Courtney Elkins at the cheetah conservation station of the National Zoo, Smithsonian Institution. Photo by Benedikt Walter. COURTNEY ELKINS (BIO ’06) IS WORKING AT the Smithsonian Institution’s National Zoological Park in the field of assisted reproductive technologies. Elkins and a team of scientists in the Department of Reproductive Sciences within the veterinary hospital, led by Dr. Budhan Pukazhenthi, are investigating methods of sperm cryopreservation. “My research is focusing on adding antioxidants to domestic cat sperm prior to freezing to increase the viability of the sperm post-thaw,” Elkins said. Cryopreservation is a process in which a species’ sperm is collected and frozen in liquid nitrogen so that it may be used to produce offspring later. The downside of cryogenic freezing is that during thawing sperm motility and integrity suffer significant loss. The loss of sperm motility makes it difficult for the sperm to reach the egg, thereby decreasing the chances of fertilization. Loss of sperm membrane integrity decreases the likelihood of egg penetration. The team is focusing on feline sperm in particular because the big cats tend to mate less frequently in the wild and their chances of a successful pregnancy are incredibly low. Also, because of environmental stresses throughout their history, various feline species have lost genetic diversity within their gene pool. This automatically harms the quality of gametes produced by the species. “I am using the domestic cat as a model for the clouded leopard, a feline species native to Southeastern Asia,” Elkins said. Experimentally, Elkins is testing whether the percentage of viable sperm post-thaw will increase with the aid of antioxidants. In the lab Elkins adds antioxidants to the sperm before freezing and then tests to see whether the quality and the quantity of viable sperm have increased after thawing in comparison to postthaw sperm without antioxidants. “If my research is successful, it could have important implications for the conservation of endangered feline species,” Elkins said. Elkins is a recipient of the Hemlinge award and has received a full scholarship and stipend from American University to pursue her master’s degree and continue her research. Catalyst Spring 2006 6 FEW GRADUATE STUDENTS CAN SAY THEIR degree consists of locating and destroying alien species. Lea Bonfiglio (BIO ’06), a second-year master’s student in environmental science, may not be hunting down extraterrestrials, but she is helping to develop a program that rids the Sligo Creek area in Maryland of invasive, nonnative plant species. Many invasive plant species are vines that strangle the growth of native plants. With nothing to prevent their growth, invasive plants can become a problem. That’s why Bonfiglio and the group of local volunteers she works with are important. Bonfiglio has an internship at Friends of Sligo Creek, a local nonprofit group, on the Removing Invasive Plants Project (RIP), where she helps to coordinate community volunteers to remove invasive plants from the Sligo Creek area. “If you can pull it, pull it,” Bonfiglio tells her volunteers. If the plant cannot be pulled, they clip it. If it cannot be clipped, they saw it, and as a last resort they may use an herbicide. The goal is to reduce the invasive plant population growth rate annually. As an undergraduate, Bonfiglio attended Rodger Williams University in New England, where she studied marine biology. She also had a marine biology internship at the Mote Marine Aquarium in Florida. Although she was doing research, she was part of a working exhibit. The laboratory had glass walls so visitors could see the research process. “Kids and adults are both tappers,” Bonfiglio said of her distracting experience in the glass box. She later became interested in conservation, which led to her applying to AU’s master’s program in environmental science, as well as her internship at Sligo Creek, which she considers rewarding. “I have gained valuable outdoor work experience, which is important for environmental assessment,” Bonfiglio said. By removing the invasive plants and gaining a better understanding of why they grow, Bonfiglio will help sustain the natural habitat of the area while getting local residents involved. RIP has events every weekend and is always looking for volunteers. For more information, contact Jane Curtin at jane_curtin@yahoo.com or 301-565-2411. THE VIRUS HUNTER By Michael Lucibella, journalism ’08 ANYONE WHO HAS INTERNET ACCESS HAS caught a computer virus at some point. What’s not clearly understood is the structure of the channels a virus takes while making its way through a network. Enter Erik Hochweller (CAP ’06), a second-semester graduate student in the computer science program. For his master’s thesis, he plans to set up a program to track the spread of computer viruses through a simulated computer “arena.” Currently, he is working with computer science professor Michael Gray on an independent study in preparation for his thesis work. Hochweller had earlier found a paper written by an IBM researcher tracking the spread of viruses. However, in several areas Hochweller found that the paper “didn’t have realistic assumptions.” The problem in the paper was that each simulated computer had one of only two states, either infected or uninfected. The IBM simulation didn’t take into account a computer that might have an antivirus program installed and already be immune. Hochweller’s strategy is to improve on the methods in the IBM study by including this third state, coming up with a more realistic model to study the channels a virus might follow. To pull this off, Hochweller is preparing to set up a simulated network of computers. Starting with 10 simulated computers, he hopes to expand the model to much larger numbers, time and software permitting. Ultimately these computer models can be used to combat a virus’s proliferation. One idea is to try to preempt a virus by spreading a “cure” through the very same channels that the virus uses and neutralize it before an infection can set in. This is only a concept so far due to privacy concerns about disseminating files (in this case the cure) the same way the virus spreads. Right now Hochweller is laying the necessary groundwork for his project. He has already contacted the author of the IBM study to see whether any more research has been done on the subject and he hopes to continue the collaboration. Anyone who has Internet access has caught a computer virus at some point. Catalyst Spring 2006 7 IN A CO U N T R Y F A R , F A R A W A Y Nilesh Tejura, right center, with other volunteers in Bangalore, India By Mishri Someshwar, journalism ’07 LAST SUMMER NILESH TEJURA (PSYC ’07) got out of Dodge . . . and how. Tejura, who is also a premedical student, spent six weeks working as a medical camp volunteer in India. Tejura began his search in early January, and by April, he had found a suitable program: the Cosmic Volunteers, a nonprofit organization that helps citizens from developed countries find volunteer positions in the Third World. Tejura was set up with a host family for six weeks from June to mid-July in the southern Indian city of Bangalore. He was assigned to work with a dermatologist in hospitals and go to medical camps, where poor patients get free treatment. Once he arrived in Bangalore, Tejura arranged to work with more than one doctor. He wound up working at five different hospitals and with six different doctors, including a gynecologist; an ear, nose, and throat (ENT) surgeon; an anesthesiologist; and an orthopedic surgeon. Much of his work was observational, with the doctors explaining to him what they were doing. “The anesthesiologist worked in the ICU, so I was able to see doctors work on a patient with a heart attack. I also got to see case files of patients to learn about their conditions,” Tejura said. Some of these cases included organophosphorous poisoning, which is more prevalent in rural India, as it is spread through the use of pesticides, Tejura said. While working with the gynecologist, Tejura saw two caesarian sections, a hysterectomy, and the removal of a zygote from a fallopian tube. Throughout the surgeries, he was in full Catalyst Spring 2006 8 surgical gear—scrubs, masks, gloves, and hair covers. While working with the ENT surgeon, Tejura got to go to a medical camp, where he was the surgeon’s assistant. And while working with the dermatologist, Tejura took glucose screenings of blood samples and determined the patient’s blood pressure. Tejura said that the experience exposed him to a wide variety of cases and made him more comfortable with the hospital atmosphere. “If I can manage for six weeks in a hospital in a foreign country, I think I should do okay over here.” CHEMISTRY PROFESSOR TESTIFIES IN LEAD POISONING CASE By Mishri Someshwar, journalism ’07 PROFESSOR JAMES GIRARD TESTIFIED IN A Rhode Island trial in October and November 2005 about lead paint poisoning. Rhode Island’s attorney general sued eight lead paint manufacturers and the industry’s trade association on the grounds that they knew lead paint was poisonous but continued to market and sell it anyway. Paint manufacturers said that their paint wasn’t a public nuisance. If people took care of their homes, they contended, the deterioration of paint would not occur at such a drastic rate and therefore would not harm residents. Girard, who was selected for the case because he specializes in analytical chemistry, testified as an expert witness for the attorney general’s office that the deterioration of paint is a natural process that cannot be avoided through better care of homes. “It’s not just about peeling paint falling off the walls. There are hazards in the normal events of living in a house,” Girard said. Over the past year, Girard went to Rhode Island to prepare samples for his testimony. Along with an industrial hygienist, Girard collected lead paint samples off the walls of some Rhode Island houses. They used an x-ray machine to find the lead-painted areas on houses. Since lead paint was banned in 1977, many houses have been painted over with non-lead paint, leading to a mix of lead and non-lead paint in the samples. “For example, if there was 25 percent lead content in the lead paint, it could fall to 7 percent in paint dust because the lead paint is mixed in with the non-lead paint,” Girard said. Girard scraped the paint, ground the samples and evaluated the content. All of the samples were prepared in accordance with federal standards. Some were so small that they couldn’t be seen by the naked eye. Yet these small samples could contaminate an entire room. The largest sample, only a few milligrams in weight, could contaminate a 1,500-square-foot house. Girard also conducted several experiments to show that even raising and closing a window can generate dust that contains lead paint whose dispersal in the air will harm residents. This is often how children get lead poisoning, he added. The trial was ongoing at publication. BIOLOGY PROFESSORS CONDUCT COSMETICS STUDY By April Astor, journalism ’06 MOST OF US WOULDN’T LOCK LIPS WITH random people off the street. There are germs to worry about. So why use the lipstick samples at department stores? Professor Zeller in the biology lab, with more than 50 cosmetics lab samples in front of her. Photo by Karen Bushaw-Newton. Last summer, biology professors Nancy Zeller and Karen Bushaw-Newton wanted to find out what people really put on their face when they use these samples. Along with the General Biology II summer class, they analyzed bacteria in 38 makeup samples from seven different stores: Hecht’s, Nordstrom, Neiman Marcus, MAC, Sephora, CVS, and Target. They also used four control samples of previously unopened makeup. Their results showed significant bacterial contamination, and some 14 samples contained potential pathogens, meaning they could cause infections. “Using one of those sampler lipsticks would be like kissing a bunch of strangers,” said Zeller. The results coincided with other experiments similar to this, she said. The experiment started when WTTG-TV in Washington, D.C., asked Zeller and BushawNewton to do the study. After Zeller showed Catalyst Spring 2006 9 them the sterilization techniques, WTTG-TV reporters collected the makeup samples, using sterile containers, broth, and cotton swabs. The summer class cultured the samples on four different agar mediums: two nutrient agar plates, a sheep blood agar plate, and a MacConkeys agar plate. The different plates can be used to test for different bacteria. Nutrient agar is a very rich medium and many kinds of bacteria will grow on it. However, there are some bacteria that have very specific growth requirements and many of those are pathogens. They can be grown on the blood agar, which has a lot of the special nutrients. “The blood agar plates allow us to visualize bacteria that may have the ability to break down blood cells,” said Bushaw-Newton. Many pathogenic bacteria are able to break down blood, either partially or completely. Zeller and Bushaw-Newton observed bacterial growth that caused both partial and complete destruction of red blood cells. Complete destruction was seen on more than one plate, indicating potentially pathogenic bacteria on those plates. Zeller said that even when the stores sanitize the makeup after use, it is not always effective. “I would never use makeup samples; we were so grossed out,” she said. But she said to keep in mind that this is “just a snapshot.” In this experiment, none of the samples from Target had any bacterial growth and Hecht’s had some of the most extensive growth. But it is possible that Target had put out fresh samples that day and that the samples from Hecht’s were a day or two old. Zeller also noted that the study tested for bacteria but it was impossible to culture and test for viruses. Viruses, though not visualized on the plates, have the potential to be transferred from one person to another via the makeup counters, Bushaw-Newton said. Something as simple as sneezing might potentially contaminate any open makeup on the counter. The study culminated in a report on WTTGTV in Washington, D.C. WHERE ARE W?HERE ARE THEY NOW? HERE A RE T HEY W THEY? PSYCHOLOGY Dr. Charles Schindler By Kelly Moynihan, journalism ’08 Dr. Charles Schindler says that there are other factors besides the actual drug that can cause drug use to turn into drug addiction. “Just using a drug does not necessarily make someone a drug addict,” Schindler said. These insights were gained through his research at the National Institute of Drug Abuse (NIDA). Schindler received his master’s in experimental psychology from American University in ’78 and then went on to earn his doctorate in the same field in 1980. He now works at NIDA, where he is a senior investigator. “I find this work most rewarding because it draws heavily from my training in psychology that I received from AU,” said Schindler. At NIDA, Schindler investigates the behavioral and physiological effects of abused drugs, specifically cocaine and methamphetamines. These preclinical trials examine what leads to uncontrolled drug use to a stage which ultimately leads to addiction. “We have shown in a number of studies that environmental and past experiences can be responsible for that change from drug use to drug addiction,” he said. To further understand the cause of drug addiction, Schindler studies the effects of cocaine and methamphetamines on rats that are trained to push a lever to receive a dose of the drug. This method, called selfadministration, allows researchers to see the effects on the rats when they are given a pretreatment drug. The pretreatment drug is a drug being considered to treat abuse. “The goal is to find a pretreatment drug that reduces the self-administration of an abused drug without having additional unwanted effects,” Schindler said. Environmental stimuli are also investigated by training the rats to react to sound and light. A tone or light signals to the rats that they can push the lever to selfadminister their drug. If the stimuli are absent, pushing the lever will not give the rats a dose of the drug. By using different combinations of tone and light, researchers saw that the rats learned when their drug was unavailable and when it could be selfadministered. Schindler said, “We use this procedure to model uncontrolled drug-taking in humans and study various manipulations or pretreatment drugs that may alter this uncontrolled, or addiction-like, intake.” “These studies may be directly related to the human drug abuse situation because we know that environmental stimuli can greatly impact human drug abuse.” For humans, drug paraphernalia such as syringes and pipes and rooms where drugtaking occurred are stimuli which increase drug use. Addicts say exposure to these types of stimuli can trigger cravings for drugs. “By providing the addict with stimuli that are not associated with drug-taking, we may be able to reduce these cravings,” said Schindler. “Ultimately, the goal of the research is to contribute to an understanding of drug abuse in a way that will lead to more effective treatments.” AU DEGREE: MS IN EXPERIMENTAL PSYCHOLOGY 1978 Catalyst Spring 2006 10 PIPING HOT: CAREER CENTER For more information on internships and jobs, visit the Career Center’s Web site at www .american.edu/careercenter. You can set up an appointment with a career or internship advisor and search the Career Center’s job database. For more information on scholarship opportunities, visit the Office of Merit Awards Web page at www.american.edu/careercenter/ oma/awardlisting.html. Staff at the office can also help you prepare your application for any of the following scholarships. SCHOLARSHIPS DEPARTMENT OF HOMELAND SECURITY SCHOLARSHIPS The Department of Homeland Security has a scholarship program for undergraduate and graduate students. The annual scholarship is offered to students in the following disciplines: physical, mathematical, computer and information, life or social sciences, psychology, selected humanities, or engineering. Applicants must be U.S. citizens as of the application deadline. Applicants who attend college full time must be in their second year of college as of the application deadline. Part-time students must complete 45 to 60 credits to qualify. Minimum GPA required is 3.3, on a 4.0 scale. Applicants cannot simultaneously be a DHS scholar and participate in a co-op program. Applicants are ineligible if they have earned a bachelor’s degree as of the application deadline or plan to study abroad in fall 2006. Scholarship winners get $1,000 per month for nine months during the academic year and $5,000 for the 10-week summer internship and full tuition payment for two years. For more information, visit www.orau.gov/dhsed. AMERICAN CHEMICAL SOCIETY/GLAXO WELCOME SCHOLARS PROGRAM Applicants must be African-American, Hispanic/Latino, or American Indian, U.S. citizens or permanent residents, and must have demonstrated financial need and have a grade point average of 3.0 or higher. Applicants must be freshmen, sophomores, or juniors studying chemistry, biochemistry, or another chemically related field, such as environmental studies. Students planning on careers in medicine are not eligible. This program provides up to $3,000 per year and is renewable. For more information, visit www.acs .org/minorityaffairs/scholars.html. Contact: Robert Hughes, Manager, ACS Scholars Program, r_hughes@acs.org, 1800-227-5558, ext. 6250 (phone), 1155 16th St. NW, Washington, DC 20036. NIH UNDERGRADUATE SCHOLARSHIP PROGRAM Scholarship recipients receive up to $20,000 a year to cover the cost of tuition, educational expenses such as books and lab fees, and living expenses such as room and board. Scholarships are awarded for one year. Recipients may reapply for additional years. Applicants must be U.S. citizens or permanent residents who come from disadvantaged backgrounds. They must be enrolled or accepted for enrollment as a fulltime student at a qualified accredited institution and have a GPA of 3.5 or better or be in the top 5 percent of their class. For more information, visit http://ugsp .info.nih.gov. INTERNSHIPS NATIONAL NETWORK FOR ENVIRONMENTAL MANAGEMENT STUDIES FELLOWSHIP This Environmental Protection Agency program allows undergraduate and graduate students to perform research projects designed by the EPA. Projects are in the general areas of environmental policy, regulation, and law; environmental management and administration; environmental science; public relations and communications; and computer programming and development. Fellows are given a stipend paid in monthly installments throughout the duration of the research project. Undergraduates should be at least juniors and must have already completed four courses relating to the environmental field. Seniors graduating before the fellowship ends must be accepted into a relevant graduate program in order to apply. This program is open only to U.S. citizens or permanent residents. For more information visit www.epa.gov/ enviroed/students.html. Call 1-800-358-8769 Catalyst Spring 2006 11 or e-mail Steve Michener at steve.michener@ ttemi.com or Sheri Jojokian in EPA's Office of Environmental Education at jojokian.sheri@epa.gov. LANGLEY AEROSPACE RESEARCH SUMMER SCHOLARS This program provides funding for internships or postgraduate fellowships for computer science, math, and environmental science research. LARSS is a 10-week summer research experience sponsored by NASA to encourage students to further their education through research and exploration in aerospace-related fields. Students must be U.S. citizens at the time of application and be classified as a junior, senior, or first-year graduate student. They must have a cumulative GPA of 3.0. For more information visit http://edu.larc.nasa.gov/larss. NATIONAL WILDLIFE FEDERATION INTERNSHIPS The National Wildlife Federation's Campus Ecology Fellowship Program offers a nationally recognized opportunity for undergraduate and graduate students to pursue their vision of an ecologically sustainable future. Through tangible projects to make their campus green and environmental research, fellows gain practical experience in the conservation field and firsthand knowledge of the challenges and opportunities inherent in successful conservation efforts. Undergraduate juniors or seniors, recent graduates, and graduate students may apply. (Special attention will be given to those who can secure their own funding.) Students from all fields of study are encouraged to apply. Applicants are selected based on a variety of measures, including professional goals, course work, job experience, résumé and cover letter, GPA, and professional and academic references. Candidates should demonstrate commitment to and experience working with multicultural communities, environmental justice, and diversity. For more information, visit www.nwf.org/ campusEcology/dspInternships.cfm. NCSE INTERNSHIPS The National Council for Science and the Environment (NCSE) offers internships for students and recent graduates during the summer and the academic year. Preference is given to students or graduates of NCSE’s University Affiliate institutions. Interns will find opportunities to attend briefings, seminars, and conferences, as well as to make important contacts. Interns will be involved in a number of NCSE programs. They may assist in outreach to the academic, governmental, business, and civil society communities and are encouraged to attend events and meetings on Capitol Hill and elsewhere in D.C. Responsibilities may include planning for NCSE’s National Conference on Science, Policy and the Environment, working with the Council of Environmental Deans and Directors (CEDD) or National Commission on Science for Sustainable Forestry (NCSSF), and helping with the Earth Portal. Additionally, interns may work on Web site design, Web page development, electronic outreach (listserv, etc.), database management, LAN support, and Web research and content evaluation. Strong candidates will be particularly interested in working on fundraising and development issues. The internship offers hands-on learning about political processes, and science and the environment; participation in a significant national initiative; Washington, D.C., experience; connections with environmental scientists and decision makers; and a $1,200 stipend. Internships usually last for three months with an opportunity for extension and promotion. They require 40 hours per week, Monday to Friday. To apply, send a résumé (include service and volunteer activities), cover letter (include dates of availability and what interests you most about the internship), a two- to five-page writing sample relevant to the environment or policy, and the names, e-mail addresses, and phone numbers for two references. All applications should be submitted to Mary Shockley at mshockley@NCSEonline.org (e-mail submissions preferred), or Mary Shockley, National Council for Science and the Environment, 1707 H Street, NW, Suite 200, Washington, DC 20006. JOBS RESEARCH ASSISTANT I AT COVANCE INC. Analyzes samples and develops methodologies for various compounds and components in compliance with SOPs and regulatory agency guidelines. Duties include organizing and conducting routine analyses in compliance with applicable methods, protocols, SOPs, and regulatory agency guidelines; documenting work and laboratory records; setting up, operating, and performing routine and nonroutine maintenance on general equipment; providing input and participating in project meetings; performing QC review of data; informing study director, principal investigator, and management of any problems and deviations that may affect the integrity of the data and participating in corrective action of problems; and assisting in setting up and performing method development and validation of various analytes in a variety of matrices. Minimum qualifications are a BS or BA degree in science or related field and 1–2 years of previous laboratory experience, or an AAS degree and 3–4 years’ experience, or a high school degree and 5–6 years’ experience. Other requirements include familiarity with the use of standard laboratory equipment, experience with analytical instrumentation, and basic knowledge of computers and software programs. Apply online at www.covance.com/careers. RESEARCH ASSOCIATE III, MOLECULAR BIOLOGY AT THE INSTITUTE FOR GENOMIC RESEARCH (TIGR) The Institute for Genomic Research (TIGR), a trailblazer in the field of genomic research, is currently seeking a research associate in molecular biology. The research associate will join the Microbial Genotyping Group in TIGR’s Pathogen Functional Genomics Resource Center and will be involved in identifying and discovering novel polymorphisms at a global genomic scale. This position is responsible for participating in the current and future resequencing projects of the lab. The research associate will contribute in the wet lab project by processing genomic DNA samples for resequencing analysis and validating the SNPs and re-sequence data by alternate methods or technology. Catalyst Spring 2006 12 Requirements for the position include a bachelor’s degree in biology, biochemistry, molecular biology, or related field and a minimum of two years’ experience; or a master’s degree in biology, biochemistry, or molecular biology with a minimum of one year of experience. Hands-on laboratory experience, preferably in an independent project, is required, and the ability and desire to work on projects independently with minimum supervision. Applicants also must have a high level of initiative. This position also requires strong skills and demonstrated experience performing PCR, hybridizations and sequencing; the ability to evaluate data and help in the designing of experiments; and the ability to operate standard laboratory equipment such as balances, centrifuges, speed vacs, spectrophotometers, and autoclaves. TIGR offers an excellent working environment and a competitive benefits package. For more information about TIGR, please see the company’s Web site at www.tigr.org. To apply for this position, log on to www.tigr.org/career.