Integrated BSc Clinical Sciences Course Director Marsha Y Morgan UCL Institute for Liver & Digestive Health Royal Free Campus http://www.ucl.ac.uk/medicine/teaching/undergraduate Clinical Sciences IBSc Knowledge and understanding of clinical science applied to medicine • Interface between basic and clinical sciences • How basic research has contributed to the understanding of disease pathogenesis and influenced clinical practice Clinical Sciences IBSc • Core 0.5 unit 12.5% • Core 1.0 unit 25.0% • Core 1.5 units (project) 37.5% • Optional unit(s) : 25.0% – Optional 0.5 unit 12.5% – Optional 0.5 unit 12.5% or – Optional 1.0 unit 25% Core Clinical Transition 0.5 Course Unit Clinical Sciences IBSc CORE: Clinical Transition • New from 2012/13 • Designed to accommodate 2nd year students • Clinical knowledge/skills sufficient for course • More intensive instruction as needed Clinical Sciences IBSc CORE: Clinical Transition • Basic training – History taking – Examination – Clinical skills • Evening ward shifts Clinical Sciences IBSc CORE: Clinical Transition Anatomy/Physiology Pathology/Disease Interactive tutorials, ward visits, bedside teaching, interaction with patients Clinical Sciences IBSc Clinical Transitions: Assessment • Reflective Diary (20%) • Diagnostic pathway poster (30%) • Ethical debate (30%) • One 2 hour unseen written examination (20%) November/ December Core The Basics of Clinical Science 1 Course Unit Eugenics Helsinki Declaration & GCP Governance & Human Rights --political correctness Data Retrieval The Pharmaceutical Industry Complementary & Alternative Medicine Advanced Investigational Techniques The Bench to the Bedside Endocrinology Gastroenterology Hepatology Metabolic Nephrology Neurology O&G Oncology Respiratory/CVS Rheumatology Surgery/OLTx Clinical Sciences IBSc Basics of Clinical Science: Assessment • One 3 hour written examination 20% • One negligence project 35% • One sleuthing project (pairs) 45% November Alder Hey Beverley Allitt Bristol Shipman Fred West Peter Sutcliffe Ian Huntley Ian Brady King’s Cross Fire Aberfan Manchester Air Disaster Moorgate Crash Hillsborough Core Project 1.5 Course Units Clinical Sciences IBSc Projects • Clinically orientated • Laboratory/investigational techniques • Wide variety of projects available • Department of Medicine • O&G, ICH/GOS and Surgery Clinical Sciences IBSc Projects Blood alcohol (m g/100m l) Ethanol Pharmacokinetics in South Asians 90 80 70 60 50 40 30 20 10 0 0 15 30 45 60 90 120 Time (min) 150 180 210 240 Clinical Sciences IBSc Projects The EEG in Hepatic Encephalopathy Clinical Sciences IBSc Projects Biomarkers in Biliary Tract Cancer Glucose nucleic acids Fructose 1,6-P2 phospholipids amino acids Phosphoenolpyruvate ADP Oncoproteins M2-PK (Tetramer) M2-PK (Dimer) ATP Lactate Pyruvate Glutamine Clinical Sciences IBSc Projects Deaths in Scleroderma New treatments unmask hidden complications Clinical Sciences IBSc Projects Dengue virus and innate immunity Basis for vaccine development Clinical Sciences IBSc Projects Assessment • Written report: 65% • Presentation & viva: 15% • Supervisor’s report: 20% June Optional Modules Optional Extras 2 x 0.5 Course Units or 1 x 1.0 Course Unit Clinical Sciences IBSc Optional Courses • Selected from other BSc programmes • List of options provided • Free choice – no restrictions Clinical Sciences IBSc Examples of Optional 1.0 Unit Courses • Foetal and Neonatal Physiology • Neurodegenerative Diseases • Biochemistry of Health and Disease • Advanced Visual Neuroscience Clinical Sciences IBSc Examples of optional 0.5 Unit Courses • Disease in History • Cancer Biology • Sex, Genes and Evolution • Clocks, Sleep & Biological Time • Physiological Monitoring • History of Asian Medicine Clinical Sciences IBSc Optional Courses: Assessment • Variable • Majority have in course assessments • Majority have 3 hour written exams in May Clinical Sciences IBSc Successes • Over 70% students awarded 1st • PhDs: x 2 2008/9; x 4 2009/10; x 2 2010/11; x 1 2011/12 • Academic foundation programme success very high • Abstracts at national & international meetings • Several papers published or in press • Research prizes and travel fellowships Clinical Sciences IBSc Selection for this Course • Up to twelve students • First choice applicants: interactive open day • Pass second year examinations • No other prerequisites Clinical Sciences IBSc Why Chose this Course? • Challenging, innovative, flexible • Clinically orientated • Highly successful • Happy students