Full Name
Address
Maxim Bruckshaw Joseph
RRA54 Resident Tutor,
University of Warwick,
Coventry, CV7 4AL.
Email M.B.Joseph@warwick.ac.uk
07908 498 447 Telephone
Date of Birth 04/01/1985
(2008 – current) University of Warwick
Ph.D ‘Microfluidic devices for DNA and protein interaction studies’.
(2007 – 2008) University of Warwick
M.Sc. (Hons) MOAC; Mathematical Biology and Biophysical Chemistry (distinction)
(2003 – 2007) University of York
B.Sc. (Hons) Biochemistry (1 st class)
Sept. 2008 -
Current
Resident Tutor (Rootes residence), University of Warwick
Live-in postgraduate for facilitation of student welfare and discipline in University residences.
July 2005 -
July 2006
Smith&Nephew Research Centre (S&N RC), York
Year-in-industry placement within RC of major multinational medical products manufacturer.
Microfluidic analytical techniques in biology and biochemistry; particularly high throughput methods.
High order regulation of gene expression through promoter and regulatory module interactions.
Design and implementation of information pipelines for rapid analysis of experimental data.
Year-in-Industry: Developed a body of evidence to support the efficacy of a proposed improvement to an existing product, including primary tissue cult/ure, protein arrays, biochemical assays and literature reviews.
Final Year Project: Cloning and expression of Metal Transport Protein (MTP) chimeras. Work indicated contribution of previously disregarded subdomains of MTP proteins to metal ion selectivity.
MOAC miniprojects: 3 x 2 month placements in (Systems Biology, Electrochemistry and Neurosciences).
Ph.D.: Primary research findings: Created library of regulatory module mutants by two step LCR process using oligonucleotides optimised by a Matlab program written by myself; Cloned mutants into promoter-containing plasmid and assessed effect of mutants on expression of GFP by flow cytometry; Designed and made PDMS microfluidic chip (water-in-oil droplets) for high throughput generation of LCR substrate mixtures.
M. Joseph and G. Koentges, “Mutant library creation by parallel assembly of partially degenerate oligonucleotides using
OptiCut,”
In preparation .
R.P. Arasaradnam, L. Wedlake, H.J.N. Andreyev, N. Ouaret, M. Joseph, C.U. Nwokolo, K.D. Bardhan, and J.A. Covington,
“A novel measure for identifying patients at risk of gastrointestinal toxicity during pelvic radiotherapy?,”
In review .
R.P. Arasaradnam, N. Quraishi, I. Kyrou, C.U. Nwokolo, M. Joseph, S. Kumar, K.D. Bardhan, and C.J. A., “Insights into
‘fermentonomics’: evaluation of volatile organic compounds (VOCs) in human disease using an electronic ‘e-nose’,”
Journal of Medical Engineering & Technology , vol. 35, 2011, pp. 87-91.
James Covington (PhD supervisor, primary)
School of Engineering, University of Warwick, Coventry, CV4 7AL
Georgy Koentges (PhD supervisor, secondary)
Biological Sciences, University of Warwick, Coventry, CV4 7AL
Alison Rodgers (Course director)
MOAC DTC, University of Warwick, Coventry, CV4 7AL
J.A.Covington@warwick.ac.uk
G.Koentges@warwick.ac.uk
A.Rodger@warwick.ac.uk