THE SCRIPPS RESEARCH INSTITUTE I0666 NORTH TORREY PINES ROAD LA JOLLA. CALIFORNIA 92037 619 455-9tOO FAX TO3 Brad Fikes Oct. DATE 3 4, FROI*I: Sue Pondrom News Bureau Manager The Scripps Research Institute 1991 OF PAGES (Including DII'}IBER Cover): 5 PEONE: (519) ss4-8290 (519) 5s4-6961 FAX: URGENT DEIJIVERY WORI,D-RENOMIED BRAIN-RESEARCE TEINK TAT{K AIINOT'NCEs IIOVE FROII ROCKEFELLER T'DIIVERSITY TO rIIE SCRIPPS RESEARCU IIISTITUTE The Institute which Contacts 7370 for senior is following is for a news embargoed president, from the Neurosciences FOR REITEASEltOlilDAY, OCT. 7. more information the Neurosciences vice release are: Patricia (NSI); Institute The Scripps (2L2) 589- Molino, and Dr. Witliam Beers, (TSRI), Research Institute (619) 554-9792 In recognition Background: scientific disciplines were to ever be (NRP) was formed a practical, research understood, the L962. 1981, in questions, and neurobiology institutions research provided direction is Founda\$n, a publicly in 1988 was the a and maintain through supported brain approach connections the the functions NRP established The world. to NSI as fundamental of NSI Prograrn the research and with NRP in are universities Sponsorship Neurosciences not-for-profit between Research new program formed. around higher Neurosciences problem-oriented autonomous organizations and In barriers traditional had to be removed if informal, theoretical that and Research organization. The NeurosciencesInstitute of the NeurosciencesResearchProgram 1230York Avenue NewYork, N.Y 10021 n2570-8975 FOR RELEASE: MON., OCT.7 FOR INFORMATION: Patricia Molino Molino * Associates.Inc. 212-689-7370 NET]ROSCIENCES INSTITT]"TE PLANS MOVE TO SCRIPPS CAMPUS NEW YORK, N.Y., Oct. 7 -- The NeurosciencesInstitute (NSD, an independent scientific center at the forefront of researchon the brain, plans to move from the campusof The RockefellerUniversity in New York City to The ScrippsResearch Institute (TSRD in La Jolla, California. TSRI is the largestprivate biomedical researchinstitution in the countrv. J GeraldM. Edelman,M.D., Ph.D., director of the NSI, and RichardA. Lerner, M.D., presidentof TSRI, announcedthat a new building will be constructed especiallyfor the NSI on the TSRI campusbefore the current agreementwith The Rockefeller University expiresin June, 1994. "The new location will doublethe size of our current quartersand enhance our opportunities to tap the growing scientific and financial resourcesof the Pacific Rim," said Henry G. Walter, Jr., chairmanof the Board of the Neurosciences ResearchFoundation,the NSI's parent organization. He added, "'We thank Rockefeller University for its hospitality during our stay, and we look forward to continuing relationshipswith Rockefellerand with the Massachusetts Institute of Technology, our prior host institution." Understanding the brain through cooperative studies sporuored by the NeurosciencesResearchFoundation Institute-- 2 Neurosciences "We're honoredthat the prestigiousNeurosciencesInstitute should choose to relocateat The ScrippsResearchInstitute,"said CharlesC. Edwards,M.D., presidentand chief executiveofficer of ScrippsInstitutionsof Medicine and Science, the parent organizationof TSRI. "Not only will this move complement and broaden our scientific investigations,it representsa major acquisitionfor the West Coast." Dr. Lerner noted that "this is an extraordinaryopportunity for TSRI. The move will strengthenboth institutions." The NeurosciencesInstitute was formed to foster understandingof how the brain functions and to promote the developmentof theories that could spur brain research. As befits the most complex of objects(the brain has 50 billion cells and a million billion connectionsbetweenthem), the NSI aims to understandthe brain at many levels, from the molecular -- how chemicalinteractionsaffectsneurons-- to the behavioral -- how we learn or remember. Dr. Edelmatr,a Nobel Laureatein Medicine in 1972, explainsthe NSI's mission this way: "The vast technicaladvancesand experimentaldiscoveriesof the past two decadeshave createda unique opportunityfor major progressin understandingthe brain. But theoriesto integratethis information are needed." He noted that the specific aim of the NSI's researchprogram is to develop biologically-basedtheoriesof the brain becausethese "are more likely to explain brain functions than are theoriesderived from non-biologicalfields, such as computer sciences,neural nets or artificial intelligence." Neurosciences Institute-- 3 Much of the researchat the NSI is basedon Dr. Edelman'stheory, which is called "neural Darwinism" or "neuronalgroup selection." One implication of this theory is that every experiencewe have shapesand alters our brain in unique ways. These changesthen affect how we respondto future experiences. The theory attemptsto take into account what has been learned about the structure and function of the brain from a broad affay of disciplines,including neurophysiology, psychology, developmentalbiology and evolutionarystudies. Computer simulationsthat are basedon Dr. Edelman'stheory are now being designedand testedat the NSI. The simulations,carried out on NSI's supercomputers,take the form of "creatures"or automatathat learn from experience to categorizeobjects, respondto novelty in their environment,and even react in unpredictableways. Practicalapplicationsof thesedevelopmentspromise to result in revolutionary new usesof computers. NSI scientistsare also developingand testingtheoriesabout touch, vision and other brain functions, as well as abouthow connectionsin the brain are strengthenedor weakened. This work can be appliedto improve the diagnosisand treatmentof nervous systemdisorders,especiallythoseconcerningmemory. In addition to its major researchactivitiesin theoreticalneurobiology, the NSI hostsvisits by researchscholarswho use the time to plan experiments,write comprehensivereviews of current research,hold intensiveresearchworkshopsor study allied disciplinesfor new insights. Sinceits founding, more than 850 scientists from 24 cotntries have participatedin the NSI's programs. Institute- 4 Neurosciences Program,an international Reaearch The NSI is alsothe homeof the Nzurusciences in 1962at the eloctedcollegeof 36 leadingscientists,whiehwase$tablished InstitutEof Technotogyto prcnote theinterdiserplinarystudyof the Massachusetts brain. The Programmovedto The RockeftllerUniversitycampusin 1982whenthe NSI wasfoundedthere. Dr. Edelmanwill moveto TSRI to headthe newly-createdDepartmentof Neurobiology,which is indElendentof the NSI. He wi{ beJoinedin that department Ph.D. by his colleagueat The RockefellerUniversity,BnrceA. Cunninghaur, The ScrippsReseatchInstltuteie intornationallyrecognizedfor its basic biomedicalresearchin struchrralandmolesulf,rbiology, chemistryandimmunology. TSRI's innovativecross-disciplinary approachto manyscientificproblemshas is attracteda numberof notedresearchers.A strongprogfamin nzuropharmacology headedby Floyd Bloom,M,D.n a prominentneffosciensstknownfor his work on andbehavioralregulation. In addition,a new Celt Biology neuropeptides in luly andsiaffedby cell biologise recognizedfor their Departmentwas established work in determiningthe stnrchrre.function relationshipsof biologicallyimporant molecules.The new Departmentof NErrrobiolry inidativeis expectedto broadert andextendtheseinterdieciplinaryresearcharorizorls.