Product datasheet
Anti-ARMS2 antibody [EPR12924] ab179440
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Overview
Product name
Anti-ARMS2 antibody [EPR12924]
Description
Rabbit monoclonal [EPR12924] to ARMS2
Tested applications
WB
Species reactivity
Reacts with: Mouse, Rat
Predicted to work with: Human
Immunogen
Recombinant fragment within Human ARMS2. The exact sequence is proprietary.
Database link: P0C7Q2
Positive control
Mouse and Rat eyeball lysates.
General notes
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the
following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long
term. Avoid freeze / thaw cycle.
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 49% PBS, 0.05% BSA
Purity
Tissue culture supernatant
Clonality
Monoclonal
Clone number
EPR12924
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab179440 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
Abreviews
WB
Application notes
Notes
1/1000 - 1/10000. Predicted molecular weight: 11 kDa.
Is unsuitable for ICC/IF,IHC or IP.
Target
Relevance
ARMS2 is thought to play a role in diseases in the elderly. Mutations in this gene have been
associated with age-related macular degeneration (ARMD). ARMD is the most common cause
of irreversible vision loss. In most patients, the disease is manifest as ophthalmoscopically
visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal
pigment epithelium and within an elastin containing structure known as Bruch's membrane.
ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific
disease mechanisms that underlie the vast majority of cases are currently unknown. However,
studies have suggested that both genetic and environmental factors may be implicated.
Cellular localization
Cytoplasmic
Anti-ARMS2 antibody [EPR12924] images
All lanes : Anti-ARMS2 antibody
[EPR12924] (ab179440) at 1/1000 dilution
Lane 1 : Mouse eyeball lysate
Lane 2 : Rat eyeball lysate
Lysates/proteins at 10 µg per lane.
Predicted band size : 11 kDa
Western blot - Anti-ARMS2 [EPR12924] antibody
(ab179440)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
Response to your inquiry within 24 hours
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We investigate all quality concerns to ensure our products perform to the highest standards
If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise,
please visit http://www.abcam.com/abpromise or contact our technical team.
Terms and conditions
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Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
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