Product datasheet
Anti-5HT7 Receptor antibody [EPR6271] ab128892
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Overview
Product name
Anti-5HT7 Receptor antibody [EPR6271]
Description
Rabbit monoclonal [EPR6271] to 5HT7 Receptor
Tested applications
WB
Species reactivity
Reacts with: Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues in the extracellular domain of Human 5HT7
Receptor.
Positive control
U-87MG, SK-OV-3, and Caco 2 cell lysates.
General notes
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the
following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Dissociation constant (KD)
KD = 8.10 x 10 -12 M
Learn more about KD
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purity
Tissue culture supernatant
Clonality
Monoclonal
Clone number
EPR6271
Isotype
IgG
Applications
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Our Abpromise guarantee covers the use of ab128892 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
WB
Application notes
1/1000 - 1/10000. Predicted molecular weight: 54 kDa.
Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
Target
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic
hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this
receptor is mediated by G proteins that stimulate adenylate cyclase.
Tissue specificity
Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is
expressed at lower levels. Isoform D is a minor isoform in term of expression.
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular localization
Cell membrane.
Anti-5HT7 Receptor antibody [EPR6271] images
All lanes : Anti-5HT7 Receptor antibody
[EPR6271] (ab128892) at 1/1000 dilution
Lane 1 : U-87 MG cell lysate
Lane 2 : SK-OV-3 cell lysate
Lane 3 : Caco 2 cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
HRP-conjugated goat anti-rabbit at 1/2000
Western blot - Anti-5HT7 Receptor antibody
dilution
[EPR6271] (ab128892)
Predicted band size : 54 kDa
Equilibrium disassociation constant (KD)
Learn more about KD
Click here to learn more about KD
Other-Anti-5HT7 Receptor antibody [EPR6271]
(ab128892)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
Response to your inquiry within 24 hours
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We investigate all quality concerns to ensure our products perform to the highest standards
If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise,
please visit http://www.abcam.com/abpromise or contact our technical team.
Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
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