Product datasheet
Anti-VRL1 antibody ab150738
2 Images
Overview
Product name
Anti-VRL1 antibody
Description
Rabbit polyclonal to VRL1
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Tested applications
IHC-P
Species reactivity
Reacts with: Human
Predicted to work with: Chimpanzee, Orangutan
Immunogen
Synthetic peptide against 15 amino acids corresponding to an internal sequence of Human
VRL1 (Q9Y5S1 NCBI, NM_016113, NP_057197.2).
Epitope
Internal.
Positive control
Human prostate tissue and human skeletal muscle tissue.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C.
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab150738 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
IHC-P
Abreviews
Notes
Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval before
commencing with IHC staining protocol. Antigen retrieval requires Proteinase K
treatment.
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Target
Function
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be
regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce
physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not
activated by vanilloids and acidic pH.
Sequence similarities
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
Contains 6 ANK repeats.
Post-translational
modifications
N-glycosylated.
Phosphorylated by PKA.
Cellular localization
Cell membrane. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma
membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in
melanosome fractions from stage I to stage IV.
Anti-VRL1 antibody images
Immunohistochemical analysis of formalinfixed, paraffin-embedded Human prostate
tissue labelled with ab150738 at 5 µg/ml.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded sections) - Anti-VRL1 antibody
(ab150738)
Immunohistochemical analysis of formalinfixed, paraffin-embedded Human skeletal
muscle tissue labelled with ab150738 at 5
µg/ml.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded sections) - Anti-VRL1 antibody
(ab150738)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
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