Product datasheet
Anti-KCNK3 antibody [S374-48] - C-terminal (Biotin)
ab186366
Overview
Product name
Anti-KCNK3 antibody [S374-48] - C-terminal (Biotin)
Description
Mouse monoclonal [S374-48] to KCNK3 - C-terminal (Biotin)
Conjugation
Biotin
Specificity
ab186366 does not cross-react with TASK3.
Tested applications
ICC, IHC-P, IHC-Fr, WB
Species reactivity
Reacts with: Mouse, Rat
Immunogen
Fusion protein corresponding to Rat KCNK3 aa 251-411 (C terminal).
Database link: O54912
Positive control
Rat brain lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long
term. Avoid freeze / thaw cycle. Store In the Dark.
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Purity
Protein G purified
Clonality
Monoclonal
Clone number
S374-48
Isotype
IgG2b
Applications
Our Abpromise guarantee covers the use of ab186366 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
ICC
Abreviews
Notes
Use at an assay dependent concentration.
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Application
Abreviews
Notes
IHC-P
Use at an assay dependent concentration.
IHC-Fr
Use at an assay dependent concentration.
WB
1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 45
kDa).
Target
Function
pH-dependent, voltage-insensitive, background potassium channel protein. Rectification
direction results from potassium ion concentration on either side of the membrane. Acts as an
outward rectifier when external potassium concentration is low. When external potassium
concentration is high, current is inward.
Tissue specificity
Widespread expression in adult. Strongest expression in pancreas and placenta. Lower
expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
Involvement in disease
Pulmonary hypertension, primary, 4
Sequence similarities
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Cellular localization
Membrane.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Valid for 12 months from date of delivery
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Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
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