Product datasheet
Anti-RAB3GAP2 antibody ab182270
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Overview
Product name
Anti-RAB3GAP2 antibody
Description
Rabbit polyclonal to RAB3GAP2
Tested applications
WB
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog, Pig
Immunogen
Synthetic peptide within Human RAB3GAP2 aa 73-122 (internal sequence). The exact
sequence is proprietary.
Sequence:
SWLQDCVLSLSPTNDLMVIAREQKAVFLVPKWKYSDKGKEEMQFAVGWSG
Database link: Q9H2M9-2
Run BLAST with
Positive control
Run BLAST with
Human fetal liver lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long
term. Avoid freeze / thaw cycle.
Storage buffer
Constituents: 98% PBS, 2% Sucrose
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab182270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
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Application
Abreviews
WB
Notes
Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa.
2 isoforms of RAB3GAP2 exist. Isoform 1 at 150kDa and Isoform 2 is expected
at 23 kDa.
Target
Relevance
RAB3GAP2 is a regulatory subunit of a GTPase activating protein that has specificity for Rab3
subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated
exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically
converts active Rab3-GTP to the inactive form Rab3-GDP. It is required for normal eye and brain
development and may participate in neurodevelopmental processes such as proliferation,
migration and differentiation before synapse formation, and non-synaptic vesicular release of
neurotransmitters.
Cellular localization
Cytoplasmic. Note: In neurons, it is enriched in the synaptic soluble fraction.
Anti-RAB3GAP2 antibody images
Anti-RAB3GAP2 antibody (ab182270) at 1
µg/ml + Human fetal liver lysate at 10 µg
Predicted band size : 23 kDa
The band detected on this Western Blot is
isoform 2 of RAB3GAP2 expected at 23 kDa.
We currently have no data about the detection
of isoform 1, which would be expected at 150
kDa.
Western blot - Anti-RAB3GAP2 antibody
(ab182270)
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Terms and conditions
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