Product datasheet Anti-Prion protease resistant protein 27-30 antibody ab187555 3 Images Overview Product name Anti-Prion protease resistant protein 27-30 antibody Description Rabbit Polyclonal to Prion protease resistant protein 27-30 Tested applications WB, IHC-P Species reactivity Reacts with: Mouse, Rat, Human Predicted to work with: Sheep, Goat, Hamster, Chimpanzee, Mink (Mustela), Non Human Primates, Cynomolgus Monkey, Macaque Monkey, Rhesus monkey, Deer, Chinese Hamster, Orangutan Immunogen Recombinant full length protein corresponding to Human Prion protease resistant protein 27-30 aa 23-230. Database link: P04156 Positive control SKOV3, Mouse brain and Mouse kidney cell extracts. Properties Form Liquid Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Storage buffer pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol, 49% PBS Purity Immunogen affinity purified Clonality Polyclonal Isotype IgG Applications Our Abpromise guarantee covers the use of ab187555 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application WB Abreviews Notes 1/500 - 1/2000. Predicted molecular weight: 27 kDa. 1 Application Abreviews IHC-P Notes 1/50 - 1/200. Target Relevance The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. Cellular localization Cell Membrane; lipid-anchor; GPI-anchor Anti-Prion protease resistant protein 27-30 antibody images Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse lung tissue labelling Prion protease resistant protein 27-30 with ab187555 at 1/100. Magnification: 400x. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prion protease resistant protein 27-30 antibody (ab187555) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling Prion protease resistant protein 27-30 with ab187555 at 1/100. Magnification: 400x. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prion protease resistant protein 27-30 antibody (ab187555) 2 All lanes : Anti-Prion protease resistant protein 27-30 antibody (ab187555) at 1/500 dilution Lane 1 : SKOV3 cell extract Lane 2 : Mouse brain cell extract Lane 3 : Mouse kidney cell extract Western blot - Anti-Prion protease resistant protein 27-30 antibody (ab187555) Predicted band size : 27 kDa Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" Our Abpromise to you: Quality guaranteed and expert technical support Replacement or refund for products not performing as stated on the datasheet Valid for 12 months from date of delivery Response to your inquiry within 24 hours We provide support in Chinese, English, French, German, Japanese and Spanish Extensive multi-media technical resources to help you We investigate all quality concerns to ensure our products perform to the highest standards If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team. Terms and conditions Guarantee only valid for products bought direct from Abcam or one of our authorized distributors 3