Introduction ......................................................................................................... 2
Course aims, fees and curriculum ..................................................................... 3
Staff details and enrolment ................................................................................. 4
Timetable overview........................................................................................... 5-6
Personal Tutors and feedback ......................................................................... 6-7
Reading list ......................................................................................................... 8
Reseach seminars, networking and lockers .................................................... 10
Assesment guidelines ....................................................................................... 11
Student responsibilities .................................................................................... 13
Moodle and Portico ...................................................................................... 13-14
Taught modules ............................................................................................ 15-24
Research project........................................................................................... 25-26
General student information ........................................................................ 27-31
Term Dates ......................................................................................................... 32
The influence of 2-D and 3-D
surface structures on cell
behaviour. 2-D materials, e.g. cell
culture plastic (A) and 3-D
microporous tissue scaffolds (B),
have very different influences on
cell behaviour when compared to
3-D nano-structured environments,
such as ECM or nanofibrous
scaffolds (C). Jell G, Minelli C and
M. Stevens, 2009. Surface
structuring biomaterials.
Fundamentals of tissue
engineering and regenerative
medicine. U. Meyer, Ed. Springer
publishing Ltd.
MSc in Nanotechnology and Regenerative Medicine
Welcome to the MSc in Nanotechnology & Regenerative Medicine and the Division of
Surgery and Interventional Science (part of one of the most prestigious medical schools in
Europe). Whilst you will be based at the Royal Free, the Division also includes three other
London campuses at Bloomsbury, Whittington, and Stanmore. Within these departments
are world class research centres specialising in tissue repair, oncology, biomedical
engineering, nanotechnology, laser medicine, and anaesthetics, to name but a few. The
overriding aim of this division is to understand the causes of human disease and develop
innovative therapies and technology to improve the quality of life of the people around us.
Nanotechnology and regenerative medicine are rapidly expanding fields which have
potential to revolutionise medicine. This unique MSc aims to equip students with
fundamental knowledge in these interdisciplinary subjects, provide an overview of the
exciting applications of nanotechnology in regenerative medicine and develop the students
transferable research skills (e.g. project planning, organisation, communication skills and
critical analyse). An in-depth laboratory based research project is an integral component of
the course, whereby the MSc will provide an expert and supportive environment for
students to investigate cutting-edge projects and thereby open up opportunities for further
research and publications. Based within the Division of Surgery and Interventional Science
also ensures that this MSc retains a clinical focus and addresses real medical needs.
Indeed you will learn about the route of translation from research ideas into actual
products which can benefit patients. Students are strongly encouraged to interact with staff
and students within the Division (and UCL) to take advantage of their expertise and build a
network of contacts for your future career. This handbook gives a brief overview of the
MSc programme for 2015/16.
On behalf of all the staff and research students involved with this MSc we warmly welcome
you to the Division and hope you have an exciting and rewarding year with us.
Dr. Gavin Jell
MSc in Nanotechnology and Regenerative Medicine Programme Director
MSc course Code: TMSNANARGM01
Course aims
To equip students with fundamental knowledge in the interdisciplinary and rapidly
expanding fields of nanotechnology and regenerative medicine.
To provide an overview of the exciting clinical applications of nanotechnology in
regenerative medicine.
To understand the processes involved in the translation of research into commercial
To develop transferable scientific research skills.
To encourage interaction with staff members and the wider scientific community.
To enhance the career prospects of students
Module Title
1. Nanotechnology in Medicine (SURGGN01)
2. Applied Tissue Engineering (SURGGN06)
3. Biomaterials in Regenerative Medicine (SURGGN05)
4. Research Methodologies (ORTHG007)
5. Practical Regenerative Medicine & Bio-nanotechnology (SURGGN02)
6. Translation of Nanotechnology & Regenerative Medicine (SURGGN04) *
6. Stem Cells in Medicine (SURGGB04) *
7. Research Project (SURGGN99)
Total Credits
Curriculum Structure
The course can be completed in one year full time (180 credits) or over a maximum 5
years as part of flexible learning. Modules for 2015/16 are listed below.
An MSc will be awarded for satisfactory completion of 180 credits and a PG Certificate
awarded for the completion of 60 credits.
The enrolment slot for our course is as indicated on your offer letter. However as this before
the course start date! students can enrol up to the enrolment deadline of 4pm on Friday 16
October 2015 at the Student Centre, UCL main Quad, Gower Street, Bloomsbury (open
Mon-Fri, 10-4pm).
The Dean of Students (Academic) has indicated that he is not prepared to approve late or
retrospective enrolment or re-enrolment for any reason
UCL’s fee schedule, together with additional information about fees, can be found on the UCL
website @
A payment of 50% of your tuition fee must be made before or at enrolment to be fully enrolled,
alternatively a letter of sponsorship indicating who should be invoiced for your fees is required.
Students can pay in two equal instalments, the first before or at enrolment, the second by 1
February 2016. No charge is made for paying in instalments, and no more than two
instalments are permitted.
Specific enquiries relating to fees should be directed to: [email protected]
Also view the new students website is at:
Staff Contacts
M.Sc. Programme Director and Module lead Dr. Gavin Jell [email protected]
for SURGN06, SURGGN99, co-SURGGN04
M.Sc. Course Director
Dr. Marilena Loizidou [email protected]
(020 7794 0500 x 35575)
M.Sc. Course Director
Prof. Alexander Seifalian [email protected]
(020 7380 2901)
Course Tutor and SURGGN05 Module lead
Dr. Wenhui Song [email protected]
(020 7794 0500 ext. 36679)
Course Tutor and SURGGN02 Module lead
Dr. Brian Cousins [email protected]
Course Tutor and SURGGN01 Module lead
Dr. Kate Ricketts [email protected]
SURGGN04 Module lead
Dr. Amir Gander [email protected]
ORTHG007 Module lead
Dr Catherine Pendegrass [email protected]
Burns, Plastics and Reconstructive Surgery Dr. Deepak Kalaskar [email protected]
Programme Lead
MSc Teaching Administrator
Ms Julie Cheek [email protected]
Campus Administrator
Mrs Chau Chong [email protected]
Estates and Health & Safety Officer
Ms Rebecca Porter [email protected]
Library, Hampstead Campus
Issue Desk [email protected]
(Site Librarian – Betsy Anagnostelis)
Tel: 020 7794 0500 ext. 33202
Library, Bloomsbury Campus
Issue Desk [email protected]
Tel: 020 7679 7792
(Cruciform Building)
MSc Nanotechnology and Regenerative Medicine
An overview of the 2015/16 timetable
All lectures will take place on the 9th Floor of the Royal Free Hospital (main Seminar Room)
unless otherwise stated. Please note this is provisional and subject to change.
Week One Induction (5 October 2015)
MSc Induction
Library induction
13:30-15:30 Royal
Welcome Party
and lunch
Free Library
ORTHG007 ( Research Meth)*
Burns & Military
Club RFS
Plastic surgery**
Tissue Engineering
International Quiz
Black boxes = welcome events; Red boxes = Divisional/hospital events that you are invited to,
Purple boxes** = Modules that you can attend but that are not assessed.
Bloomsbury Open Lunch time lectures
*Lectures in Bloomsbury main campus
Term 1 (12 October – 18 December 2015)
Personal tutor
Workshops* /Translation**
ORTHG007 ( Research Meth)
Bloomsbury Campus
Burns & Military
Stem cells **
Club RFS
Plastic surgery**
Tissue Engineering
MSc Journal Club
Orange boxes = Course activities
*Personal tutor meetings – these are to be arranged by your tutor but a timetabled slot is available.
*Workshops will run for 4 weeks from the 12th October.
**The optional modules (Translation of Science/Stem cells) start on Monday 2nd and Thursday 5th November
2015 respectively.
** Purple boxes = Modules that you can attend but that are not assessed.
MSc Nanotechnology and Regenerative Medicine Overview Timetable – 2015/16
Term 2 (11 January – March 2016)
Practical’s (SURGGN02)
Practical’s (SURGGN02)
Stem cells
Club RFS
Tissue Engineering
MSc Journal Club*
Term 3 (March – July 2016)
Examination Period:
End of February – mid March 2016
Research project submission date: End of July 2016
Viva Exam will be conducted:
End of August/First week of September 2016
Personal Tutors
A Personal Tutor will be allocated to you within the first 4 weeks of the first term start date
If you have not been allocated a personal tutor or any issues arise within this time frame
you must contact the programme tutor (Gavin) or administrator (Julie).
A Personal Tutor is there to: Discuss any academic or personal problems.
 Someone to get to know and maintain regular contact.
 Readily accessible within the department.
 First contact with regard to any complaints or problems. Your tutor will decide whether
to refer to another member of Academic staff or what action should be taken.
 Establish a good relationship with students in order to provide support and
Tutorial groups
Tutorial groups will be held with your personal tutor (once a month for the first term and by
arrangement in the next two terms) to discuss academic work and progress. These
tutorials can be used to discuss a course topic which the students would like to revisit, they
could act as revision learning sessions or indeed any cover any other area the students
are interested in (related to Nanotechnology and Regenerative Medicine). These should
be student led discussions using the expertise and knowledge of the tutor. These tutorials
are timetabled for Monday afternoons once a month but will be dependent on tutor
Student Feedback
Student feedback is very important in delivering a course that meets students’ needs.
Therefore we strongly encourage feedback (both positive and negative). There are several
forums available to give feedback (staff/student committee and questionnaires). However,
direct feedback can be given at any time to any of the course tutors, administrator, or your
personal tutor. At the end of each module and at the end of the course you will also be
asked to complete a feedback questionnaire.
Staff / Student Consultative Committee
At the start of term students will be asked to select up to 3 student representatives. The
selected people will represent the Nanotechnology and Regenerative Medicine students’
views at the Divisional Staff/Student Consultative Committees (DSSCC) which will meet
once every term.
The representatives should be a conduit for your suggestions, complaints and general
comments. Representatives should provide a verbal report, to their student group, as
appropriate. Minutes of the meetings will be uploaded to Moodle for all students to
access. The dates for 2015/16 DSSCC meetings are to be arranged.
Suggested Reading
Due to the recent expansion of these fields, journal reviews and research papers are
excellent ways to explore these emerging fields. However, some books which you may find
useful are listed below (all available from the Royal Free Hospital Library)
Nanotechnology in Medicine (SURGGN01)
1. Nanotechnology: a gentle introduction to the next big idea - Ratner, Mark A., Ratner,
Daniel c2003
2. Nanotechnology - Schmid, Günter c20083. Quantum theory cannot hurt you: a guide to the universe - Chown, Marcus 2007
4. Nanotechnology for dummies - Boysen, Earl, Muir, Nancy 2011
5. Nanomaterials: inorganic and bioinorganic perspectives - Lukehart, Charles M.,
Scott, Robert A. c2008
6. Intelligent surfaces in biotechnology: scientific and engineering concepts, enabling
technologies, and translation to bio-oriented applications - Grandin, H. Michelle,
Textor, Marcus c2012 Preview
7. Principles of regenerative medicine - Atala, Anthony 2011 Online Resource
Applied tissue engineering (SURGGN06)
1. Principles of tissue engineering - Lanza, R. P., Langer, Robert S., Vacanti, Joseph,
NetLibrary, Inc 2007
2. Essentials of stem cell biology - Lanza, R. P. 2009
3. Fundamentals of tissue engineering and regenerative medicine - Meyer, Ulrich 2009
4. Intermittent hypoxia and human diseases - Xi, Lei, Serebrovskaya, Tatiana V. c2012
5. Principles of regenerative medicine - Atala, Anthony 2011
6. Online Resource
Applied Biomaterials (SURGGN05)
1. Biomaterials science: an introduction to materials in medicine - Ratner, B. D.
2. New materials and technologies for healthcare - Hench, L. L., Jones, Julian R., Fenn,
Michael B. c2012 (electronic resource)
3. Intelligent surfaces in biotechnology: scientific and engineering concepts, enabling
technologies, and translation to bio-oriented applications - Grandin, H. Michelle,
Textor, Marcus c2012
4. Principles of regenerative medicine - Atala, Anthony 2011 Online Resource
Practical Regenerative Medicine & Bio-nanotechnology (SURGGN02)
1. Culture of animal cells: a manual of basic technique and specialized applications Freshney, R. Ian c2010.
Translation of Science (SURGGN04) 5 items
1. The art & science of technology transfer - Speser, Phyllis L. c2006
2. Pharmaceutical biotechnology: fundamentals and applications - Crommelin, D. J. A.,
Sindelar, Robert D., Meibohm, Bernd c2008
3. The Financial Times guide to business start up 2013 - Williams, Sara 2012
4. Writing science: how to write papers that get cited and proposals that get funded Schimel, Joshua c2012
5. Successful scientific writing: a step-by-step guide for the biological and medical
sciences - Matthews, Janice R., Matthews, Robert W. 2007
Research Seminars, Networking and Facebook
In addition to the regular lectures students are encouraged to engage with the wider
regenerative medicine and nanotechnology community at UCL, London and the UK.
Regular seminars will be posted on the sites below and students are encouraged to join
these groups. A Facebook web page with friends of the MSc is available – please join and
contribute. This will hopefully become a tool for networking and communication..
London Centre for Nanotechnology
London Regenerative Medicine Network
Access to the Division and lockers
Each student will be allocated a Fob key to gain entrance to the Division of Surgery and
Interventional Science (9th floor of the Royal Free Hospital) and a locker within the same
location. A deposit of £10 will be paid by the students on allocation of the keys. Please
look after your keys, if you lose either key you will be charged £10 replacement cost. The
deposit will be returned at the end of the year, when you give back your keys. Please
contact Chau Chong ([email protected]) if you lose your keys.
Monday research lectures
In addition to your lectures, there are weekly research seminars which, in the first term
(lunch time 12:00-13:00pm), which you are expected to attend. Talks will be given by past
MSc students, PhD students and invited lecturers. These will be very useful opportunities
to learn about research in these fields and an excellent networking opportunity (drinks
Full details will be available on Moodle
Marking System
The marking system has evolved to ensure that marking is fair and just. The system
varies according to the work that has to be marked.
Course Assessment and Essays
It is not possible to mark these in a double blinded fashion, but in-course work will be
marked in a single blinded manner by two markers who will be unaware of the mark that
the other marker has assigned. These marks will then be averaged. Comments will be
written on the work handed back to you. The marks awarded and the comments made will
be agreed by both markers.
Marking of Exams
Your examination scripts will be identified by a unique code number, which UCL will
designate to each candidate. These scripts will be marked in a blind fashion by two
markers and an average mark calculated. Any large discrepancies between the two
separate marks will be discussed and a consensus reached. If a consensus is not
reached then this will be referred to the External Examiner. This code will only be broken
when all of the marks from the course assessment and the projects are assembled. For
this reason examination marks will not be given out prior to the end of the course.
Requirement for a Pass
To achieve a pass:
1) the overall mark, based on 180 credits, is 50% or greater
2) the mark for the dissertation is 50% or greater, and
3) Only one module marks will be condoned between 40-50%
Requirement for a Merit
To achieve a pass:
1) the overall mark, based on 180 credits, is 60% or greater
2) the mark for the dissertation is 60% or greater, and
3) there are no marks below 50%, no condoned marks, no re-sits, and all marks are
based on first attempts.
Requirement for a Distinction
1) the overall mark, based on 180 credits, is 70% or greater
2) the mark for the dissertation is 70% or greater, and
3) there are no marks below 50%, no condoned marks, no re-sits, and all marks are
based on first attempts.
Any module in which the student scores less than 50% can be retaken the following year.
Additional fees may be required for re-taking exams. Final marks will be decided at the
Nanotechnology & Regenerative Medicine MSc Board of Examiners meeting held in
September, UCL examinations will then ratify these marks and provide the final results on
Portico. Any marks received prior to this are provisional.
Submitting Coursework
Written work must be submitted via TurnItIn® within the MSc Moodle site, in addition two
paper copies of each essay must also be handed in to the designated person on the given
date by 4.00 p.m. or as agreed with the module organisers.
You will be given instruction on how to use TurnItIn® - depending upon the assignment - a
maximum of 10% copyright is condoned.
Late handing in of essays or projects will result in marks being deducted as follows:
Penalties for Late Submission of Coursework
Where coursework is not submitted by a published deadline, the following penalties will
A penalty of 5 percentage marks should be applied to coursework submitted the
calendar day after the deadline (calendar day 1).
A penalty of 15 percentage marks should be applied to coursework submitted on
calendar day 2 after the deadline through to calendar day 7.
A mark of zero should be recorded for coursework submitted on calendar day 8 after
the deadline through to the end of the second week of third term. Nevertheless, the
assessment will be considered to be complete provided the coursework contains
material than can be assessed.
Coursework submitted after the end of the second week of third term will not be
marked and the assessment will be incomplete.
Coursework submitted after solutions have been released will receive a mark of zero,
and may not be formally marked, even when the coursework was submitted within
seven calendar days of the deadline. Nevertheless, the assessment will be considered
to be complete provided the coursework contains material that can be assessed.
In the case of dissertations and project reports submitted more than seven calendar
f) days after the deadline, the mark will be recorded as zero but the assessment would
be considered to be complete.
Where there are Extenuating Circumstances that have been recognised by the Faculty
2. Extenuating Circumstances Panel, these penalties will not apply until the agreed
extension period has been exceeded.
In the case of coursework that is submitted late and is also over length, then the greater
3. of the two penalties shall apply. This includes research projects, dissertations and final
Should Tutors fail to return work promptly (within 4 weeks of receiving the essay); you
should inform the Staff / Student Committee Representatives so that it may be brought up
at the next Committee meeting.
Extra marks will be awarded to students who indicate they have read additional
information relating to the subject. However, this should be concise and relevant;
extraneous material will be ignored.
Should Tutors fail to return work promptly (within 4 weeks of receiving the essay); you
should inform the Staff / Student Committee Representatives so that it may be brought up
at the next Committee meeting.
Extra marks will be awarded to students who indicate they have read additional
information relating to the subject. However, this should be concise and relevant;
extraneous material will be ignored.
Timekeeping, Responsibilities and Dress
You should advise the Course Administrator, Course Tutor or the Module Organiser if you
are unable to attend a mandatory lecture. Their email addresses are listed on the Course
Organisation page. A minimum of 75% attendance is required for all compulsory
modules. Attendance below this amount (without prior consent from the course director)
will result in a possible annulment of your student visa (for overseas students) and you
may be prevented from sitting examinations. If you are unable to attend a lecture please
contact Julie Cheek.
Please attend all lectures on time. This is very important as staff are very busy, particularly
those who are clinicians who work to a very tight schedule and may not be able to delay or
postpone their lectures. Attendance sheets will only be available in the first 10 minutes of
a lecture and lateness will be counted as not attending a lecture (see above).
When not attending lectures (and once MSc projects have been allocated) you should be
working on your projects. If you are unable to come to work you should contact your
project supervisor. Project supervisors will report to the course tutors regarding student
Appropriate laboratory dress: For laboratory work legs or feet must be covered i.e. no
open-toed shoes or sandals should be worn. Laboratory coats will be provided. For cell
culture it is important to have good personal hygiene.
Moodle is UCL’s Electronic Learning Environment, and is used to access course material
on line. The web portal is: You will need your UCL email
address and password.
The MSc in Nanotechnology and Regenerative Medicine Moodle site will contain all the
information about the course (including a full course hand-book), lectures, coursework
deadlines, upcoming course events and changes to the time-table. Moodle will also be
used to send you emails about course updates. Coursework will also be submitted using
Moodle (TurnItin®). Students are also encouraged to use forums for self-directed learning.
Please make sure you regularly check the course Moodle site for timetable changes
and news as it is an important channel for information.
Portico: The UCL Student Information Service
PORTICO is the UCL Student Information System. Access to PORTICO is available via
the web portal You will need to logon using your UCL user-id and
password, which are issued to you once you have enrolled. The password is the same for
accessing UCL restricted web pages, UCL email and the Windows Terminal Service
(WTS). If you do not know them, you should contact the IS Helpdesk as soon as possible
( or tel. 020 7679 5000. Further IT guidance is available at:
In PORTICO you can:
 edit your own personal data e.g. update your home and term addresses, contact
numbers and other elements of your personal details;
 view data about courses/modules;
 view your results online
As a student you can take ownership of your own personal data by logging on to
Portico Helpdesk (Mon-Fri 10-4pm) can be contacted via [email protected] or tel. 020 7679 0637.
See ‘Documentation Links’ in on the Portico Home Page for instructions on module
registration or contact Julie for guidance.
Complaints Procedures
If you have a complaint to make about your experience at UCL, you should make every
effort to try to resolve the matter informally. You should first make your complaint known to
your Personal Tutor or with another member of staff whom you feel able to consult. In
cases where informal discussion fails to resolve the matter, you may wish to consider
making use of UCL's Centralised Complaints Procedure which is available on the following
The centralised complaints procedure does not apply in areas where a separate student
Grievance Procedure is already operating. The UCL Union also operates a separate
complaints procedure. Please see:
SURGGN01: Nanotechnology
Small, useful and very strange! This module provides an introduction to nanotechnology, and
how the shift from classical to nanoscale science brings with it huge potential for medical
Targeted drug delivery
Imaging and diagnosis
Tissue scaffold design
As we visit the quantum universe, we will see how nanoscale objects can be tuned for highly
specific, highly sensitive disease targeting. Students will see how such small scale technology
offers huge leaps in diagnostics and therapeutics, enabling us to break the boundary from
macroscale anatomy to nanoscale biologics. Anatomical imaging is transformed to functional
imaging; treatment becomes targeted. Students will receive a background in clinical imaging
modalities (MRI, x-ray CT) and cancer therapies (radiotherapy), and the current and future role of
nanotechnology in these fields.
Module Lead: Dr Kate Ricketts
Venue: Lectures will take place in the Jerry Kirk Seminar Room, within the Division of Surgery and
Interventional science on the 9th floor of the Royal Free every Thursday (13:00-15:00).
Credits: 15 credits, mandatory module
Methods of assessment: Coursework (20%) and unseen 2-hour written exam: (80%). This
consists of 3 questions (choice of 6).
Exam date: To be confirmed
Overview Timetable: SURGGN01: Every Thursday at 13:00-15:00
SURGGN02: Tissue culture and Bionanotechnology
A practical introduction to experimental
techniques required in tissue regeneration
and biomaterial-cell interactions. This
module will familiarise students with the
laboratory setting and develop good
experimental planning techniques and the
analysis IN
experimental results.
This SEM image of a bone resorbing cell
module will consist of lectures, workshops (osteoclast - pink) on bioactive glass.
and practical’s
E. Gentleman, Biomaterials (2010)
Module Lead: Dr Brian Cousins. 4 week module to run from 11 January 2016.
Venue: In laboratories and seminar rooms on the 9th floor of the Royal Free.
Credits: 15 credits, mandatory module
Course aim: To provide students with practical research skills in nanotechnology and
regenerative medicine, in addition to transferable skills in experiment planning and
Methods of assessment
1. Laboratory assessment (50%):
a. Lab skills (25%): Practical mark based on laboratory (cell culture) skills. A
detailed marking sheet (proforma) has been designed for above.
b. Written report (25%) – A report on the cellular behaviour on nanocomposite
scaffolds. The report will be double marked, according to an agreed
2. Written exam (50%) – This will be a two hour exam. The exam will consist of one
one-hour multiple choice questions and two half-hour questions on concepts and
problem solving. .
Exam date: To be confirmed
SURGGN02 Outline
Details to be confirmed but will start on 11/1/2016 for 4 weeks and sessions held every
Monday 9:00-12:00, Tuesday 14:00-18:00, Thursday 9:00-12:00 and Friday 09:00-12:00.
(This is subject to change but a final timetable will be confirmed during term 1)
L1 Histology and tissue structure
L2 Basic Cell culture + cell culture practical
L3 Cell analytical techniques
L4 Gene expression
L5 Basic immunology
L6 Immunological Techniques
L7 RNA interference
L8 Optical Microscopy/Electron Microscopy
L9 Review
P1 Laboratory orientations & basic cell culture
P2 Passaging cells - trypan blue counting and freezing down
P3 Gene expression
P4 Cell analytical techniques 1 - Seed polymers (10,00cells/cm2)
P5 Cell analytical techniques 2 - MTT & total DNA
P6 Material Characterisation
P7 Gold nanoparticle synthesis and characterisation
Workshops will run concurrently with practical’s (half of group in each)
W1 Basic lab skills - pipetting, measuring & solution workshop
W2 RT-PCR quantitative analysis (computer lab?)
W3 Experimental planning
W4 MTT and DNA result analysis
W5 Calculating nanoparticle number
W6 Revision
SURGGN06: Applied Tissue engineering
The course introduces students to the use of tissue
engineering as a strategy to replace or restore a level of
function to diseased or damaged tissue. Students will
learn about how direct cell behaviour e.g. stem cell
differentiation, though material design. World leading
scientists and surgeons will provide lectures on
engineering specific tissues and discuss future strategies
in scaffold design.
Jell G et. al (2010). Raman spectroscopy a tool for
tissue engineering. P. Matousek Ed. Springer
publishing Ltd.
Module Lead: Dr Gavin Jell
Venue: The lectures will take place in the Jerry Kirk Seminar Room, within the Division of
Surgery and Interventional science on the 9 th floor of the Royal Free at 14:00- 16:00 every
Credits: 15 credits, mandatory module
Course aims: To introduce students to the emerging technologies in the field of tissue
engineering, including; differing tissue engineering strategies, tissue scaffold design
Methods of assessment: Coursework 20% (write a scientific review article). Unseen 2hour written exam: (80%). This consists of 3 one-hour long questions (choice of 6).
Exam Date: To be confirmed
Overview Timetable: SURGGN06– Tissue Engineering every Friday at 2pm
Applied Tissue Engineering 1-3pm Fridays
Introduction - what is tissue engineering? GJ
How tissue regenerate: mimicking nature VM/GJ
Angiogenesis and hypoxia in Tissue Engineering GJ
Cell sources for tissue engineering GJ
Controlling scaffold degradation rate and growth factor delivery GJ
Deans prize (date to be confirmed)
Decellularised v Synthestic scaffolds for TE G/P
Cell response to mechanical stress/electrical stimuli NE
Student review presentations
Nerve tissue engineering JP
Tissue engineering for modelling disease ? TM
Cardiovascular tissue engineering (grafts and stents) AdM
Muscoskeletal Tissue Engineering 1: Bone GJ
Muscoskeletal Tissue Engineering 2: Cartilage SR?
Skin tissue engineering (VM/RBt)
Review and summary
SURGGN05: Biomaterials in Tissue Regeneration
An introduction to material properties, biomaterial design,
regenerative medicine. This module will provide students
with a basic understanding of biomaterial properties, an
understanding of material-cell interfaces and various
approaches to modify materials to promote desirable cell
responses (including nanoscale bio-functionalisation and
surface structuring)
Jell G et. al (2009). Surface structuring biomaterials. U.
Meyer, Ed. Springer publishing Ltd.
Venue: The lectures will take place in the Jerry Kirk Seminar Room, within the Division of
Surgery and Interventional science on the 9th floor of the Royal Free at 10:00 - 12:00 every
Module Lead: Dr Wenhui Song
Credits: 15 credits, mandatory module
Course aims: To develop students understanding of material properties, material
characterisation, the biological-material interface and how surface structuring can change
biological interactions.
Methods of assessment: Coursework (20%) and unseen 2-hour written exam: (80%).
This consists of 3 questions (choice of 6).
Exam Date:
To be confirmed
Time table: SURGGN05. Every Tuesday at 10:00-12:00
What are biomaterials? WS
Material Chemistry – what are materials? GJ
Materials in Medicine Material surface properties? GJ
Structure and physical properties of material - WS
Polymers (natural and artificial) - WS
Composites and nanocomposites – WS
Bioceramics and glasses - GJ
Metals (alloys stents – orthopaedic – dental) WS
Host response to biomaterials 1 (0-30min) - GJ
Cell : biomaterial
Host response to biomaterials 2 (30min-30 years) Coursework seminar: A case study of a biomaterial
11 Coursework seminar
Christmas break 15th December 2014 - 9th January 2015
Biomaterials fabrication from top-down to bottom up -WS
Review and summary
Physical (mechanical, thermal & topography) – WS
Biochemical (Raman, FTIR, MRI) – GJ
Micro-/nano scale topography (optical, SEM, TEM, AFM,
SIMS, XPS) Characterisation –DK
Lab workshop - WS/DK/BC/GJ/AdM
ORTHG007: Research Methodologies
A shared module teaching the basic transferable research
skills required for a successful research scientist. Topics
include scientific writing “critical thinking”, research
planning, statistics and presentation skills. Students should
develop a basic understanding of frequentist statistics and
improve their presentation/communication of research
ideas and data.
Venue: Whittington Hospital (Archway), Undergraduate Centre, Level 3, Highgate Wing,
unless stated otherwise in the timetable. Tuesday afternoons, 2-5pm, October-December.
Please refer to the ORTHG007 Moodle site as it will supersede information in this
Module Lead: Dr Catherine Pendegrass
Credits: 15 credits, mandatory module
Course aims: To present and give basic training of transferable research skills to
students, such as critical analysis and presentation skills. To give an overview and basic
training of statistical processes; this will enable students to incorporate statistics into
their individual research projects.
Methods of assessment: Course work is an integral part of the module. Although
coursework will not be allocated marks that count towards the official course assessment,
students are expected to attempt and complete work on time as part of their learning
experience, both for soft skills and statistics. The module is designed in such a way that
learning acquired from the didactic or interactive teaching is consolidated by further
exercises. Therefore students are expected to complete the coursework.
Exam: The module is assessed by a multiple choice exam and practical SPSS
statistics questions which lasts for 2 hours.
Provisional Date: 15 December 2015. The exact date will be confirmed by the module
NB: This module will provide invaluable skills for the rest of the course – including the
research project.
ORTHG007 Lecture Timetable
Tues. 6th Oct
Oct 2015
Catherine Pendegrass
Prof. Robert Brown
Welcome and An Introduction to Research Methodologies.
Dr Gavin Jell
Managing Bibliographic
information [P1].
Dr Gavin Jell and Course
Managing Bibliographic
information [P2].
(hands on tutorial on
reference manager).
Research Integrity.
Ideas, originality, technology
vs. science, scientific methods,
controls, testing, falsification,
and validation.
The use of scientific databases
Group 1 – Royal Free Library –
Telsa Room
Group 2 – Database Room,
Cruciform Library
Group 3 – Stanmore Library
Tues. 20th
Oct 2015
Dr Gavin Jell
Prof. Allan Hackshaw
Prof Robert Brown
Dr Rifat Hamoudi
Intro to Stats and SPSS
“Why are We Here?"
Prof. David Abraham
Research Enterprise.
Dr Rifat Hamoudi
Dr Rifat Hamoudi
Precision of Estimates
and Hypothesis Testing.
The Paired t-test.
Review of descriptive SPSS Exercise.
Crossing the Great Divide into Clinic: Lessons from
Regenerative Medicine.
The independent t-test Statistics Lecture
and one-way ANOVA.
Paired t-test and SPSS SPSS Exercise
Oct 2015
Tues 3rd Nov
Tues. 10th
Nov 2015
Norman Williams (NW) &
Chris Brew-Graves (CBG)
Prof Martin Birchall
Dr Rifat Hamoudi
Dr Rifat Hamoudi
Managing bibliographic
information AND –Critical
Sources of information / use of
search engines. What makes a
citations - Use of citation
managers. Why publish? the
peer-review process. What
makes a good/bad paper?
Critique of study design &
An Introduction to Epidemiology.
Scientific Research”
NW - Why and How.
CBG - Assessing Impact.
Paper: Scary or Simples
Examples of developing new
[laboratory] research. How it
happens and what its impact
can be.
Getting published: structure of
dissertations, papers, reviews,
grants, public dissemination.
Data & Descriptive Statistics.
Getting Data into SPSS.
Tech Transfer, Patents &
Collaborating with industry,
consultancy, confidentiality.
Statistics Lecture.
Nov 2015
Nov 2015
Prof. Alan Cottenden
“Mind the Gap!” (it's more
than the language and
the food).
Dr Rifat Hamoudi
Dr Anne
Vanhoestenberghe (AV)
& Dr Henry Lancashire
Dr Rifat Hamoudi
Correlation and linear
Categorical Data: The
Chi squared test, odds
logistic regression.
Career Sat Nav.
Dec 2015
Dec 2015
Dr Rifat Hamoudi
Dr Rifat Hamoudi
Dr Melanie Coathup
Dr Rifat Hamoudi
Dr Catherine Pendegrass
Common Issues in Data
Problem Solving
The Three
Working between contrasting
Biomedicine and Eng. &
Interdisciplinarity, Science-Tribes,
Specialities, Networking.
Statistics Lecture
Statistics Lecture
Navigating you way through
the academic system (AV)
The Fellowship Application
Process (HL)
Statistics Lecture.
SPSS Exercise.
How do we choose our animal
models for in vivo research.
The 3 R’s – what are they and
why are they important.
Student Stats Q&A
and viva
Coping with nerves :
design, Presentation
different audiences.
SURGGN04: Translation of Nanotechnology
nanotechnology and regenerative medicine – from
“bench to bedside”. Students will learn about:
Routes of translation.
The importance of IP
GMP- & conformity of assessment.
Avenues of investment
Demonstrate awareness of investment
avenues for commercialisation.
6. Ethical issues approval for clinical trials.
7. The economics in the translation of an idea
into a commercially available product.
Cellular uptake of functionalised nanoparticles (image by Dr. G. Jell)
Location: Jerry Kirk Seminar Room - Division of Surgery and Interventional science on
the 9th floor of the Royal Free. Module Lead: Dr Amir Gander
Credits: 15 credits, optional module
Brief description:
The aim is to provide students with the knowledge and tools to take novel nanotechnology
and regenerative medicine based products through to commercialisation and clinical
Methods of assessment:
The course will be assessed 100% by coursework. Students will prepare a grant, judge
these grants, prepare a business plan for the translation of a regenerative medicine
technology and then present this proposal to a panel of judges (Dragon’s Den style). The
proposal must show innovation, commercialization potential and a viable route to market.
Provisional time table: SURGGN04 – Translation of nanotechnology
Introduction - What is translational research/Routes to market
Company creation and health economics
Innovation and enterprise (making ideas happen)
Funding Science - Government, Charities and private
Intellectual Property
Regulation of Regenerative Medicine
Grant writing and costing
Dragons Den
SURGGB04: Stem cells in regenerative medicine
Stem cells hold the promise to impact human health. Their
innate ability to self-renew and unique developmental
capacity enables generation of unlimited numbers of
multiple types of differentiated progeny. These features
could be exploited to develop cellular therapies for the
repair or replacement of diseased and damaged tissues in
the clinic. This module will give students a broad
introduction to stem cell biology, progressing to cover in
more detail many of the distinct types of stem cell studied
in current stem cell research and their potential for use in
regenerative medicine and tissue engineering.
Figure: Schematic showing developmental potential of pluripotent stem cells. Light micrograph of induced pluripotent stem (iPS) cells in
culture on a feeder layer of mouse embryonic fibroblasts. Immunofluorescence micrograph depicting iPS-derived hepatocytes stained
for alpha-fetoprotein (FITC) and actin (PE).
Module organiser: Dr Ashleigh S. Boyd
Location: Jerry Kirk Seminar Room, Division of Surgery and Interventional Science, 9 th
Floor, Royal Free Hospital
Brief description: The syllabus will include a number of topics which will be important for
the application of stem cells in surgery including: basic stem cell biology, sources of stem
cells, methods to generate or isolate populations of stem cells, current regulations and
ethical considerations for the use of human stem cells and applications of stem cell based
therapies in the clinic.
Module aims: This module will act as a primer on stem cell biology and the potential
therapeutic application of stem cells in surgery. Students will learn about ongoing research
and applications currently available for patient care. The module will also address
important ethical and regulatory concerns for the use of stem cells and potential scientific
barriers to the use of stem cells in the clinic.
Upon completing this module students will have an understanding of the basics of stem
cell biology and the essential requirements for stem cell based therapies, pre and post
operatively and in surgery; knowledge of which may be utilized going forward to the
research project stage of the MSc.
Module assessment: The module will be assessed by an exam (MCQ and SEQs) lasting
2 hours (worth 100%).
Exam Date: To be confirmed
SURGGN99: Research Project
This module accounts for 50% of the final MSc mark and provides hands-on research
experience within a skilled and supportive environment. Students will complete a
regenerative or nanotechnology themed research project and will be encouraged to
publish their results in peer reviewed journals (if appropriate). Details of earlier MSc
research projects can be found online. 2014/2015 projects will be available in
Comparrison of bone nodules formed from stems cells and primary cells. E. Gentleman,
Jell G et. al (2009). Nat. Materials 8 , 763-70
Project Allocation
A booklet containing a summary of all the available projects will be given to you in
November. Students are expected to decide which projects interest them and contact the
relevant supervisors. A Project research day will occur (provisionally scheduled for the 10th
November 2014) where supervisors will present a summary of their projects and be
available for informal questions regarding the project. Students are expected to have
decided and started on their project before the end of the 1st term. Projects will be hosted
throughout UCL
During the research project module students will be expected to work full-time under the
guidance of their supervisor, organising, running and advancing their practical project
either working individually and / or liaising within a team.
Project Oral Presentations
Students will be asked to present their projects in the 2nd term to check progress, ensure
clear project aims are set and deliverables have been decided upon. In addition, students
will be expected to present their final results and conclusions to their peers and other
research staff within the department at the end of the year as part of their project Viva.
Project Thesis
Students will be required to write-up their research work as a thesis. This thesis is worth
80% of the project mark. The guidelines for the write up must be strictly adhered to and will
be posted on Moodle.
All students will be given a viva which will consist of a 10 minute presentation based on
your followed by a “thesis defence” this will be worth 20% of your final project mark. Viva’s
will take place on the 1st week in September – please make sure you are available.
It is impossible to mark projects in a double blinded fashion. All projects will be marked by
two examiners. Marking will be done independently and the average mark calculated after
marks from the two Internal Examiners have been obtained. If the marks vary by more
than 10% the examiners will agree on the final mark. Any discrepancies between these
marks will be referred to the External Examiner. The projects will be marked using a
standardized mark allocation sheets which can be found on Moodle.
Project Submission
Projects must be submitted using the TurnItIn®UK service at before
4.00 pm on the 29 July 2016.
In addition, two bound hard copies (blue cotton
binding) and one electronic copy must be submitted before 4.00 pm on the 29 July
2016. Your supervisor may also request a copy.
Students should write up their projects individually. Supervisors may read over the work
prior to handing in to give some feedback on content. However the thesis should be a true
reflection of the student’s own work and thoughts.
Project Extensions
A project extension may be allowed in extenuating circumstances. You must submit a
completed “Permission to Extend a Research Project Deadline” form (found on UCL
website or see Julie). Extensions will only be given in special circumstances and require
both the agreement of your supervisor and the course tutor (Gavin).
Extenuating Circumstances
All submissions regarding extenuating circumstances relating to coursework,
projects or examinations must be submitted to Julie Cheek.
Cases must be supported by documentary evidence such as a medical certificate, doctor’s
letter or other relevant evidence.1 Submission must be made either at the time of or as
soon as possible after the incidence of the circumstances concerned, and, in any case, no
later than seven days after the date of the assessment or examination affected. In very
exceptional circumstances, a case can be made by the Board of Examiners to the Chair or
Deputy Chair of the UCL Board of Examiners to take into consideration medical and/or
extenuating circumstances submitted after this deadline.
If you are not coping with your workload or have a personal problem that is affecting your
work please see your personal tutor at the earliest opportunity. The form can be
accessed and downloaded from Moodle or ask Julie.
UCL Student Administration and Information
Enrolment for new students
Enrolment for fresher’s will take on the main UCL Gower Street site in the Cloisters. Only
first year students will be required to enrol in person. Maps of the Bloomsbury
campus and the surrounding area are available at Guides will
be available within the Quad during the enrolment period to help with directions. The final
deadline for enrolment for the 2015/16 year is 4pm on 16 October 2015. We recommend
you arrange your formal enrolment at your earliest opportunity.
Full details about enrolment will be sent to all new students in early September. New
students from overseas who attend the Orientation Programme for International Students
will have the opportunity to enrol there.
Dyslexia Assessment and Support Centre
The UCL Dyslexia Assessment and Support Centre provides a free diagnostic assessment
service for UCL students. Current assessment reports are required when applying for the
DSA (Disabled Students' Allowance) and for special examination arrangements. Specialist
tutorial support for students with dyslexia is also available. If you require special
examination arrangements you need to contact Disability Services without delay to
arrange a formal assessment:
Access to Learning Fund and Student Hardship Fund
Details of the Access to Learning Fund and the UCL Student Hardship Fund is available to
help students who have made realistic provisions to fund their studies and have
experienced unforeseen financial hardship. Awards are made towards maintenance costs
only in the region of £1,000 in exceptional circumstances a larger award may be made.
Applicants may be students in any Faculty and in any year of their programme of study.
UCL Scholarships
For details of all other scholarships please see the online Student Handbook pages:
Data Protection Policy
Please refer to UCL Estates and Facilities: Data Protection on the following link:
Intellectual Property Rights
Please refer to the online Student Handbook pages on Intellectual Property Rights on the
following link:
Policy on Plagiarism
You should note that UCL has now signed up to use a sophisticated detection
system “TurnItIn®” to scan work for evidence of plagiarism, and the Department
intends to use this for assessed coursework. This system gives access to billions
of sources worldwide, including websites and journals, as well as work previously
submitted to the Department, UCL and other universities
UCL is subject to the University of London's General Regulations for Internal Students and
the policy detailed below has been drawn up in accordance with those Regulations.
Plagiarism is defined as the presentation of another person's thoughts or words or
artefacts or software as though they were a student's own.
Any quotation from the published or unpublished works of other persons must, therefore,
be clearly identified as such by being placed inside quotation marks, and students should
identify their sources as accurately and fully as possible.
A series of short quotations from several different sources, if not clearly identified as such,
constitutes Plagiarism just as much as does a single unacknowledged long quotation from
a single source. Equally, if a student summarises another person's ideas, judgments,
figures, diagrams or software, a reference to that person in the text must be made and the
work referred to must be included in the bibliography.
Recourse to the services of "ghost-writing" agencies (for example in the preparation of
essays or reports) or of outside word-processing agencies which offer
"correction/improvement of English" is strictly forbidden, and students who make use of
the services of such agencies render themselves liable for an academic penalty.
Some departments give specific advice about non-originality, plagiarism and the use of
materials by others, and students must make themselves aware of such departmental
guidelines and abide by them. For some assessments it is also illicit to reproduce material
which a student has used in other work/assessment for the course or programme
concerned. Students should make themselves aware of their department's rules on this
"self-plagiarism". If in doubt, students should consult their Personal Tutor or another
appropriate Tutor.
Failure to observe any of the provisions of this policy or of approved departmental
guidelines constitutes an examination offence under the UCL Regulations. Examination
offences will normally be treated as cheating or irregularities under the regulations for
proceedings in respect in respect of Examination Irregularities. Under these Regulations
students found to have committed an offence may be excluded from all further
examinations of the University and/or UCL.
UCL Union
UCLU Rights and Advice Office
Offer confidential advice on Immigration Rights; Grants; Loans; Financial Advice; Housing;
Council Tax; Legal Advice Sessions & much more.
Contact: Tel: 020-7679-2998
UCLU is based at: 15 Gordon Street, London, WC1H 0AY.
Student Welfare
We understand that undertaking a Master’s degree, living in London, finances and
worrying about your future can cause considerable stress. If you have any problems that
are affecting your wellbeing please discuss these with your personal tutor and/or contact
the UCL student councillors –
Welfare and support for International Students
Drop in advice centre for all students
Out of office hours try phoning Nightline, the confidential listening and support service for
students, by students.
Contact: 0207 6310101
Opening hours: 6.00pm-8.00am during term-time
Royal Free Campus Information
Sharing a modern building with the Royal Free Hospital, the Royal Free campus is situated
in attractive Hampstead, close to the heart of London. Most of the academic units based
at the Royal Free campus were previously part of the Royal Free Hospital School of
Medicine which, in August 1998, merged with UCL. The Royal Free Campus is now one of
UCL Medical School’s main teaching and research sites.
The University Department of Surgery is on the 9th Floor of the Royal Free Hospital.
Directions to UCL Royal Free Campus
Underground/Tube: Northern line
Coming from the south, take an Edgware branch train and get off at Belsize Park tube
station. Turn right out of the station up Haverstock Hill until you come to a pub named The
George; turn right after the pub down a small road called Rowland Hill Street; this road
bends to the right to the entrance to the Royal Free Hospital School of Medicine. From the
tube station to the entrance will take approximately 5 minutes to walk.
Overground/British Rail
Hampstead Heath, British Rail station is very close to the hospital and serves stations to
Richmond and Clapham Junction to the west and Stratford to the east.
24 Victoria Warren Street Station, Mornington Crescent Station, Camden Town Station,
Malden Road, South End Green (for Royal Free).
46 Kensal Rise Queens Park Station, Warwick Avenue Station, Maida Vale, St John's
Wood Station, Swiss Cottage Station, Hampstead Station, South End Green (for Royal
Free), Kentish Town, King's Cross Station.
168 South End Green Pond Street (for Royal Free), Belsize Park Station, Haverstock Hill,
Chalk Farm Station, Camden Town Station, Eversholt Street, Euston Station.
268 Finchley Road Swiss Cottage, Belsize Park, Royal Free Hospital, Hampstead Station,
Whitestone Pond, Golders Green.
C11 Archway Station Parliament Hill Fields, Gospel Oak, South End Green, Pond Street
(for Royal Free), Belsize Park Station, Swiss Cottage Station, Finchley Road Station, West
Hampstead, Cricklewood Station, North Cricklewood, Brent Cross.
By Car
There are a limited amount of car parking spaces in a two story car park entered from
Pond Street or some marked spaces in Rowland Hill Street. They are pay and display.
Accidents/ Safety:
Everyone is expected to act with due care and consideration for the safety of
themselves and others within the department. If you see anything that you consider
hazardous then please notify Steph Bogan or Chau Chong (general admin office)
immediately. The Safety Policy is displayed on the Notice board. All accidents or
injuries incurred on the premises must be reported to Steph Bogan or Chau Chong.
An accident form must be completed.
Emergency Contacts:
First Aid:
The department’s trained first aider: Steph Bogan or Chau Chong (general admin
office). There is a First Aid kit sited on the wall of the corridors next door to the
General Admin Office (Room 9/333).
You will need your UCL user name and password to
access UCL password protected sites.
Notice Boards:
Several notice boards are erected in the Department. Please look at these regularly as
notices of seminars; courses, College announcements, etc are also displayed on these
Out-of-Hours Access:
No student is allowed to work on “experimental laboratory bench-work” outside normal
working hours (Monday to Friday 9.00 – 18.00) unless DIRECTLY SUPERVISED.
For other activities such as library, writing up and computer work, a designated person
must be in the vicinity. Authorisation must be sought prior to working out-of-hours (i.e.
evenings and weekends).
Photocopying can be done in the library where a photocopying card can be purchased.
Please note that our insurance policy does not cover personal possessions of staff and
students, and in the unfortunate event anything is stolen or damaged, we are not
responsible for replacement as a department.
This covers the main queries you are likely to have, however please do not
hesitate to ask your course Tutor about anything else that is of concern to you.
College Terms: Academic Year 2015– 2016
First Term
Monday 28 September 2015 - Friday 18 December 2015
Second Term
Monday 11 January 2016 - Wednesday 23 March 2016
Third Term
Monday 25 April 2016 - Friday 10 June 2016
College Closures
CLOSE - Wednesday 23 December
2015 at 5.30 p.m
RE-OPEN - Monday 4 January 2016
CLOSE - Wednesday 23 March 2016 at
5.30 p.m.
RE-OPEN - Wednesday 30 March 2016
Bank Holidays
CLOSED - Monday 2 May 2016
CLOSED - Monday 30 May 2016
CLOSED - Monday 29 August 2016
PhD students Benyamin, Tina and Leila (who graduated from
the MSc in 2010 and have now completed or are submitting
their PhD within the Division of Surgery\)