MAJEKODUNMI O. FATOPE, PhD
Department of Chemistry, Sultan Qaboos University, Muscat, Oman
E-mail: majek@squ.edu.om
Personal Information
Place and date of birth:
Nationality:
Civil status:
Omu-Ekiti, November 13, 1952.
Nigerian.
Married with three children.
Academic Record
1. 1993-94: Postdoctoral Fulbright Research Scholar, Purdue University, W/Lafayette, Indiana, USA.
Advisor: Professor Jerry L. McLaughlin.
2. 1983-84: Postdoctoral Fogarty Research Scholar, The Ohio State University, Columbus, Ohio USA.
Advisor: Professor Heinz G. Floss.
3. 1976-1980: PhD University of Ibadan, Nigeria.
Thesis: Synthesis of potential antisickling and antiinflammatory agents related to 3,4-dihydro-2,2
dimethyl 2H-1-benzopyran-6-butyric acid, (DBA).
Advisor: Professor Joseph I. Okogun.
4. 1972-1975: BSc Chemistry (Second class upper division) University of Ibadan
Project: Attempted synthesis of an indole alkaloid.
Advisor: Professor Domingo A. Okorie.
5. 1970-1971: Higher School Certificate (A’ Level) Chemistry, Biology and Physics; and Subsidiary
Mathematics, St. Thomas Aquinas College, Akure, Nigeria.
6. 1965-1969: West African School Certificate (O’ Level) Division One, St. Joseph’s College, Ondo,
Nigeria.
Other Studies

Bioassay Techniques: Residential course on Bioassay Techniques for Detection and
Fractionation of Bioactive Natural Products, ICIPE, Nairobi, Kenya, 18 – 24th November 1990,
sponsored by the International Organization for Chemical Sciences in Development (IOCD)
and funded by the Commonwealth Foundation.
Employment Record
2011-14: Head Department of Chemistry, Sultan Qaboos University (SQU)
2012- Professor, SQU, Oman
2003-12: Associate Professor, Sultan Qaboos University Oman.
2003 - : Retired from service as a Professor at Bayero University Kano (BUK), Nigeria.
1997-03: Assistant Professor, SQU, Oman.
1997-03: Leave of Absence from BUK, Nigeria to SQU, Oman.
1994-: Professor BUK, Nigeria.
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Majek. O. Fatope
1994-95: Purdue University, West Lafayette, Indiana, USA (Fulbright Research Scholar)
1990-94: Reader, BUK, Nigeria.
1984-90: Senior Lecturer, BUK, Nigeria.
1983-84: The Ohio State University, Columbus, Ohio, USA, (Fogarty Research Scholar)
1981-84: Lecturer I, BUK, Nigeria.
1980-81: Lecturer II, BUK, Nigeria.
1975-76: National Youth Corps in Kano, Kano State; taught A’ level chemistry at the
College of Advanced Studies Kano, Nigeria.
1974: Research Scientist (Vacation employment, July-September) at the Nigerian
Tobacco Company Ibadan; analyzed cigarette brands for sugar and nicotine.
1973: Tax Assessment Assistant (Vacation employment, July-September) at the
Revenue Office, Onireke Ibadan Nigeria; conducted tax assessments.
Publication Record
1. BN Al-Sabahi, MO Fatope, MM Essa, S. Subash, SN Al-Busafi, FSN Al-Kusaibi, and T
Manivasagam, Pomegranate seed oil: Effect on 3-nitropropionic acid induced neurotoxicity in PC
12 cells and elucidation of unsaturated fatty acids composition, Nutritional Neuroscience (Impact
Factor 2.1), Accepted 2014. (Ahead of Print)
2. 2John R. Williams, Majekodunmi O. Fatope, Salma M. Z. Al-Kindy, Fakhr Eldin O. Suliman,
Salim H. Al-Saidi. Volatile Compounds of the Leaves and Flowers of Lavandula dhofarensis A. G.
Miller, SQU Journal for Science, 2013, 18, 33-40
3. A. Mann., K. Ibrahim, AO Oyewale, FO Amupitan, MO Fatope, JI Okogun Isolation and
elucidation of three triterpenoids and its antimycobacterial activity of Terminalia avicennioides
American Journal of Organic Chemistry 2012, 2 (2) : 14-20
4. A Mann, K Ibrahim, AO Oyewale, JO Amupitan, MO Fatope, JI Okogun Antimycobacterial
friedelane-terpenoid from the root bark of Terminalia avicennioides, American Journal of
Chemistry, 2011, 1, 52-55.
5. MO Fatope, GB Varma , NM Al-Azri, RA Marwah and RS Nair, Kaurane Diterpenoids from
Blepharispermum hirtum, Chemistry and Biodiversity, 2010, 7, 1862-1870.
6. AK Onifade, MO Fatope, ML Deadman, SMZ Al-Kindy, Nematicidal activity of Haplophyllum
tuberculatum and Plectranthus cylindraceus oils against Meloidogyne javanica, Biochemical
Systematics and Ecology, 2008, 36, 679-683.
7. MO Fatope, RGM Marwah, NB Al Hadhrami, AK Onifade, JR Williams, Identification of the
Chemotype of Ocimum forskolei and Ocimum basilicum by NMR Spectroscopy, Chemistry and
Biodiversity, 2008, 5, 2457-2463.
8. RG Marwah, MO Fatope, ML Deadman, JE Ochei, SH Al-Saidi, Antimicrobial activities and the
major components of the herb oil of Plectranthus cylindraceus, J. Applied Microbiol., 2007, 103,
1220-1226.
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Majek. O. Fatope
9. RG Marwah, MO Fatope, ML Deadman, YM Al-Baqbali and J Husband Musanahol: a new
aureonitol-related metabolite from a Chaetomium sp., Tetrahedron, 2007, 63, 8174-8180.
10. RG Marwah, MO Fatope, R Al Mahrooqi, GB Varma, H Al Abadi, Al- Burtamani, Antioxidant
capacity of some edible and wound healing plants in Oman, Food Chemistry, 2007, 101, 465-470.
11. GB Varma, MO Fatope, RG Marwah, ME Deadman, FK Al-Rawahi, Production of phenylacetic
acid derivatives and 4-epiradicinol in culture by Curvularia lunata, Phytochemistry, 2006, 67, 19251930.
12. MO Fatope, RG Marwah, AK Onifade, JE Ochei, YKS Al Mahroqi 13CNMR analysis and antifungal
and insecticidal activities of Oman dill herb oil, Pharmaceutical biology, 2006, 44, 44-49.
13. FEO Suliman, MO Fatope*, SH Al-Saidi, SMZ Al-Kindy, RG Marwah, Composition and
antimicrobial activity of the essential oil of Pluchea arabica from Oman. Flavour Fragr J. 2006, 21,
469-471. Impact factor 1.849 (2010).
14. SKS Al-Burtomani, MO Fatope, RG Marwah, AK Onifade, SH Al-Saidi, Chemical composition,
antibacterial and antifungal activities of the essential oil of Haplophyllum tuberculatum from Oman,
J. Ethnopharmacol., 2005, 96, 107-112. Impact factor 2.466 (2011).
15. OM Ameen, MO Fatope, LA Usman, SA Adebayo, Bioactive metabolites in improved cowpea
seeds, African Journal of Biotechnology, 2005, 4, 513-516.
16. MO Fatope, RS Nair, RG Marwah, HHS Al-Nadhiri, New sesquiterpenes from Pluchea arabica, J.
Nat. Prod., 2004, 67, 1925-1928.
17. MO Fatope, SKS Al-Burtomani, JO Ochei, AO Abdulnour, SMZ Al-Kindy, Y. Takeda, Muscanone:
a 3-O-(1”, 8’’, 14’’-trimethylhexadecanyl)naringenin from Commiphora wightii. Phytochemistry,
2003, 62, 1251-1255.
18. MO Fatope, SKS Al-Burtomani and Y Takeda, Monoacylglycerol and fatty acids of Punica
granatum seed oil, J. Agric. and Food Chemistry, 2002, 50, 357-360. Impact factor 2.816 (2010).
19. MO Fatope, L Salihu, SK Asante and Y Takeda, Larvicidal activity of extracts and triterpenoids
from Lantana camara. Pharmaceutical Biology, 2002 40, 564-567.
20. MO Fatope, Retigabine ASTA Medica, Current Opinion in Investigational Drugs Journal, 2001, 4,
93-98.
21. MO Fatope, Soretolide Laboratoires Biocodex, Current Opinion in Investigational Drugs Journal,
2001, 4, 824-827.
22. MO Fatope, SMZ Al-Kindy and AO Abdulnour, Natural products as pest, microbial disease and
tumor control agents, J. Scientific Research - Science and Technology, Special Review, 2000, 5571.
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Majek. O. Fatope
23. MO Fatope, OA Adoum, Y Takeda, C18 Acetylenic fatty acids of Ximenia americana with potential
pesticidal activity, J. Agric. and Food Chemistry, 2000, 48, 1872-1874.
24. MO Fatope, OA Adoum, Y Takeda, Oleanene Palmitate from Ximenia americana, Pharmaceutical
Biology, 2000, 38, 391-393.
25. AO Adoum, NT Dabo, MO Fatope, Bioactivities of some savanna plants in the brine shrimp
lethality test and in vitro antimicrobial assay, Int. J. Pharmacognosy, 1997, 35, 334-337.
26. MO Fatope, L Zeng, JE Ohayagha, JL McLaughlin*, New 19-acetoxyingol diterpenes from the
latex of Euphorbia poisonii (Euphorbiaceae), Bioorganic & Medicinal Chemistry, 1996, 4, 16791683.
27. MO Fatope, L Zeng, JE Ohayagha, G. Shi, J. L. McLaughlin*, Selectively cytotoxic diterpenes
from Euphorbia poisonii, J. Med. Chem., 1996, 39, 1005-1008.
28. MO Fatope, OT Audu, Y Takeda, L Zeng, G Shi, H Shimada, JL McLaughlin*, Bioactive entKaurene Diterpenoids from Annona senegalensis,” J. Nat. Prod. 1996, 59, 301-303.
29. AM Nuhu, FM Musa, MO Fatope, Pesticidal effects of extracts from Balanites aegyptica L,
Spectrum, 1995, 2, 82-88.
30. G Shi, D Alfonso, MO Fatope, L Zeng, Z-m Gu, G-x Zhao, K He, JM MacDougal, JL McLaughlin*,
Mucocin: A new annonaceous acetogenin bearing a tetrahydropyran ring, J. Am. Chem. Soc.,
1995, 117, 10409-10410.
31. MO Fatope, AM Nuhu, Y Takeda, Cowpea weevil bioassay: A simple pre-screen for plants with
grain protectant effects, Int. J. Pest Management, 1995, 41, 84-86.
32. MO Fatope Phytocompounds: Their bioassay and diversity, Discovery and Innovation, 1995, 7,
229-236.
33. MO Fatope, H Ibrahim, Y Takeda, Screening of higher plants reputed as pesticides using Brine
shrimp lethality assay, Int. J. of Pharmacognosy, 1993, 31, 250-254.
34. MO Fatope, A simple way to visualize stereochemical relationships in substituted cyclochexanes,
J. Sci. Teach. Assoc. Nig., 1991, 27, 135-137.
35. MO Fatope, Y Takeda*, et al. Cucurbitane Triterpenoids from Momordica charantia, J. Nat. Prod.
1990, 53, 1491-1497.
36. MO Fatope, MS Abdullahi, A facile synthesis of 2,2-dialkychroman-6-carboxaldehyde, J. Chem.
Soc. (Nig.), 1989, 14, 43-46.
37. MO Fatope, Y Takeda, New phenolic glucosides from Lawsonia inermis, J. Nat. Prod. 1988, 51,
725-729.
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Majek. O. Fatope
38. MO Fatope, Y Takeda, The constituents of the leaves of Ocimum basilicum, Planta Medica, 1988,
54, 190.
39. MO Fatope, DJ Abraham, Design synthesis and testing of potential anti-sickling agents 10. 2,2Dimethylchroman-6yl alkanoic acids, J. Med. Chem., 1987, 30, 1973-1977.
40. MO Fatope, AE Adeniyi, Enhanced methyation of sodium carboxylates in methyl ethyl ketone,
The effect of quaternary ammonium salts, Synth. Commun. 1985, 15, 307-310.
41. MO Fatope, TM Zydowsky, HG Floss, Oxidative Degradation of O6-Methyl guanine with Oxone, J.
Chem. Res. (S), 1984, 308-309.
42. JI Okogun, OM Olawore, EEU Ekong, MO Fatope, Meliacin (Limonoid) reactions: Photoreaction
of gedunin and khivorin derivatives, Bull. Chem. Soc. Nig., 1982, 7, 113-120.
43. MO Fatope, JI Okogun, A convenient solvent-specific synthesis of 4(4-acetoxy-3-methyl-but-2enyl)phenyl) butyric Acid, J. Chem. Soc. Perkin I, 1982, 1601-1603 (now published as J. Org. &
Biomol. Chem.)
44. MO Fatope, JI Okogun, Aluminum chloride catalyzed cyclialkylation of 1-(2-metho-xyphenyl)-3methylbut-2-ene, Bull. Soc. Chim. Belg., 1981, 90, 847-848.
45. MO Fatope* and SN Al-Busafi, Natural products in the prevention and treatment of invasive
human diseases In Natural products and their active compounds on disease prevention, M.
Mohamed Essa and E. Sukumar (Eds), Nova Science Publisher, Inc, ISBN: 978-1-62100-153-9
NY 2012, Chapter 9, 165-182.
https://www.novapublishers.com/catalog/product_info.php?products_id=28697&osCsid=)
Research Grant Record
 2010: Awarded SQU Internal Research Grant (IG/SCI/CHEM/11/02), USD 16,000.
Title: “Chemical composition, biocidal and antioxidant capacity of plants used in herbal skin care” (MO
Fatope - Principal Investigator; N Sherwani, S Al-Saidi and S Al-Butamani College of Science).
 2001-2006: Awarded His Majesty’s Strategic Research Grant (SR/CHEM/01/01), USD 500,000.
Title: “Bioactivity-driven chemical investigation of Omani biodiversity for medicinally and agronomically
valuable compounds: The development of Omani natural products” (MO Fatope* - Principal Investigator,
AO Abdulnour, SMZ Al-Kindy, JR Williams, FE Suliman, A Elshafie - Co-Investigators – College of
Science; M Deadman, Co-Investigator – College of Agriculture and Marine Sciences, and J. Ochei, CoInvestigator – College of Medicine).
 1999-2002: Awarded Sultan Qaboos University Research Grant (SCI/99/05), USD 13,000.
Title: Bioassay based discovery of antifungal and anti-bacterial agents” (MO Fatope - Principal
Investigator, AO Abdulnour, SMZ Al-Kindy, Co-Investigators – College of Science, J. Ochei, CoInvestigator – College of Medicine).

1997-2001: Awarded the International Foundation For Science (IFS) Research Grant (F/20182F), USD 12,000.
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Majek. O. Fatope
Title: Biomass-based management of the pests of cowpea and edible vegetables in sub-Saharan West
Africa” (MO Fatope - Principal Investigator).
 1993-1994: Awarded a Senior Fulbright Research Scholar Grant (18425).
Title: “The search for botanical pesticides for cowpea, millet and sorghum pests”
(MO Fatope, Research Sabbatical - Principal Investigator).

1992-1995: Awarded the International Foundation for Science (IFS) Research Grant (F/2018-1),
USD 7,000.
Title: Bioassay-directed identification of pesticides from plants,” (MO Fatope - Principal Investigator).
 1983-1984: Awarded the Fogarty International Research Fellowship (FO5TW03423).
Title: “Steric course of nucleic acid alkylation by chiral methyl” (MO Fatope Postdoctoral).
Intellectual property development
MO Fatope, AK Onifade, M Deadman, SMZ Al-Kindy. Nematicidal composition of essential oil and
method of preparation. GCC Patent Application No. GCC/P/2005/4410, 12th March 2005.
Research interest
My research specialization/expertise is medicinal chemistry (Design, synthesis, and testing of organic
compounds)/natural products, and I have been engaged in:

Bioassay-guided isolation and characterization of biologically active natural products (antiinfective, anti-cancer, anti-oxidant, crop protection agents and fragrant disinfectants) from plants.

Design, synthesis, testing and evaluation of small chemical entities derived from natural products
containing suitable pharmacophores for development as anti-sickling, anti-inflammatory and
anticonvulsant and crop protection agents

Bioassay-guided isolation and characterization of anti-infective from microorganisms gathered
from unusual environments.
Membership of professional bodies


Member, American Chemical Society, 1988 to the present
Affiliate member, The International Union of Pure and Applied Chemistry (IUPAC), 1987 to the
present.
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Majek. O. Fatope