Middle Tennessee State University Office of Intellectual Property and Commercialization

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Middle Tennessee State University

Office of Intellectual Property and Commercialization

Seeks partner to license

Label-free surface wave sensor for analysis of biomolecular interactions

This portable sensing device can analyze static binding in microarrays to a sensitivity of ~1.5 µ g/mL (4pg per 265 µ m spot) using a technology similar to that used in surface plasmon resonance sensors, but without the requirement for metal films or a flow configuration.

The multilayer sample platform is the size of a microscope slide, can be inexpensively mass-produced, and can be custom-prepared using any commercial microarrayer.

Exposure to a (multi)analyte solution, followed by rinsing and automatic 3-D scanning, is all that is required to get an image like the one above. The device is easy to use, suitable for research, and potentially for clinical applications.

Applications: Research and Commercial

DNA binding Clinical

Protein/Antibody immunosensing

Kinetics

Forensic/Homeland Security

Food Safety

Environmental

Advantages

Increased sensitivity

Decreased background interference

Detect trace amount of biological and chemical entities

Label-free

No fluorescent or radioactive labels

Decreased cross-reactivity

Less expensive

Inexpensive disposable sample substrate

A dry, pre-prepared array can be stored until needed

Versatile design

Tailored to your size range and sensitivity needs

Microarray-based sample prep

The Inventor

Dr. William Robertson is a Professor of Physics at Middle Tennessee State University. He earned his doctoral degree from Purdue University and has twenty years of experience in the area of surface EM waves and optics in academics, industry, and government laboratories.

Dr. Robertson works closely with an interdisciplinary group of biologists and chemists to develop this device and its applications.

For more information on licensing contact:

Middle Tennessee State University

Office of Intellectual Property and Commercialization

615-898-5005 email: research@mtsu.edu

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