Biology 111B: Unity of Life Fall 2015 Syllabus Instructor: Office: Office Phone: Email: Leslie Saucedo TH257F 879-2788 lsaucedo@pugetsound.edu Office Hours: Monday noon-1pm Tuesday 11:00-noon --or by appointment Texts: How Life Works, 1st ed., 2013, Morris et al. with Launchpad subscription: course URL: http://www.macmillanhighered.com/launchpad/morris1e/1850272 A Student Handbook for Writing in Biology, 4th ed., 2013, Knisely Course Description Biology 111 is an introductory level course that examines living organisms primarily at the molecular and cellular levels. Biology 111 is designed for students intending to major in biology or a related science and also fulfills the natural sciences core. Course Objectives I. To understand and apply five core concepts of biology: 1. Evolution: The diversity of life evolved over time via genetic alterations and selection of resultant phenotypes (from the protein to organismal level). 2. Structure and function: Structure reflects function (from molecules to organisms). 3. Information flow, exchange, and storage: Organisms interact with their environment through the context-dependent expression of the genetic information that they inherit (from cells to organisms). 4. Pathways and transformations of energy and matter: Biological systems grow and change by processes based upon chemical transformation pathways and are governed by thermodynamics. 5. Systems: a quantitative understanding of complex biological processes at multiple functional scales. II. To gain experience with scientific methodology. III. To communicate science in a clear and concise manner. IV. To develop analytical reasoning skills. V. To recognize the interplay between scientific advances and the broader community (individuals, government, corporations) Class Sessions Lecture section B meets M, W and F at 10am in TH395. Lecture topics and readings that complement each lecture are provided in the attached schedule. A brief read though the corresponding readings prior to lecture is HIGHLY recommended. Pay particular attention to the figures as they often present a concise, visual summary. You will find “Pre-Class Assignment” questions on Launchpad; they are “assigned” to help you know which material I will emphasize during lecture, though they will not count towards your class grade. A more careful reading following lecture will then allow you to focus on material that is more challenging for you. Again, on Launchpad you will find “Homework” questions assigned (but not graded) as an opportunity to self-assess your understanding. Lectures will include student participation in the form of questions posed to the students, group exercises and class discussions. Additionally, students are wholly encouraged to ask the instructor to clarify points that are unclear during the lecture. Labs The laboratory component of Biology 111 (held in HA251) is designed to accompany and extend subjects introduced in the lecture. Each student must be registered for a lab section of the course and attendance is mandatory. In EXTENUATING CIRCUMSTANCES ONLY, you may be able to attend a different lab section than for which you are registered, provided that you first seek approval of the instructor(s). Labs cannot be made up after the last lab section of the week has met (at which time the equipment/reagents are removed and the following week’s lab is set up). To improve the quality of your lab experience, come to lab prepared. Carefully read the lab exercise (and any associated readings) BEFORE coming to lab. Most of the lab exercises contain pre-lab questions that MUST BE COMPLETED AND SUBMITTED AT THE BEGINNING OF THE LAB SESSION. Late pre-lab questions will not be accepted. Preparing for labs in this manner is essential for establishing confidence and competence while performing lab activities. All lab exercises will include some form of written assignment designed to strengthen comprehension of lab topics and develop scientific writing skills. Quizzes and Exams There will be six short quizzes given over the course of the semester (see schedule). QUIZZES WILL BE GIVEN DURING THE FIRST TEN TO FIFTEEN MINUTES OF LECTURE. NO ADDITIONAL TIME FOR ARRIVING LATE WILL BE GIVEN. However, you will be able to drop your lowest quiz score (only 5 quizzes will contribute to your final grade). These short quizzes are designed to help the student identify any areas of weak comprehension before taking exams. Three “mid-term” exams (see schedule) will each be 50 minutes in length. Exams will consist of some objective (multiple choice, matching and completion) but primarily short answer questions (explanations, inference and application). The topics covered by each exam are indicated in the schedule and will include material from lectures, laboratory and readings. THERE WILL BE NO MAKE-UP OF EXAMS OR QUIZZES. Absence for a bona fide medical reason will require written evidence and MAY (OR MAY NOT) be considered in assigning the final grade. The final exam is scheduled for Friday, December 18th from 8:00-10am. This exam will include a section on material following the third “mid-term,” material from topics covered earlier in the course, and will require you to integrate the important concepts covered throughout the semester. THE FINAL EXAM MUST BE TAKEN AT THE SCHEDULED TIME. Readings How Life Works (1st ed., 2013, Morris et al.) is a comprehensive text designed for a year-long introductory biology course. It covers many more topics than Biology 111 and also occasionally goes into greater depth on some subjects that are discussed in lecture. This text and accompanying online study tools found on Launchpad at: http://www.macmillanhighered.com/launchpad/morris1e/1850272 should greatly assist in understanding information presented in lecture and lab as well as serve a valuable resource as you continue your studies in the biological sciences. Readings continued A Student Handbook for Writing in Biology (4th ed., 2013, Knisely) has been adopted by the biology department as a guide for writing papers in all biology courses. This handbook provides guidance for scientific writing and presentation (including construction of figures, tables, graphs and posters) required of this course and future biology courses. Academic honesty All assignments must be written individually. CHEATING, PLAGIARISM, AND OTHER FORMS OF ACADEMIC DISHONESTY WILL BE REPORTED AND RESULT IN ACADEMIC PENALTIES. You are responsible for understanding what constitutes academic honesty. Definitions and examples of academic dishonesty and the resultant penalties can be found in The Logger, the University’s academic handbook: http://www.pugetsound.edu/student-life/personal-safety/student-handbook/ Grading Final letter grades will be based on your total accumulated points at the end of the semester based on the following approximate percentages: 5 quizzes (2% each): 3 “mid-term” exams (15% each): final exam: laboratory: TOTAL: 10% 45% 20% 25% 100% Office of Student Accessibility and Accommodation If you have a physical, psychological, medical or learning disability that may impact your course work, please contact Peggy Perno, Director of the Office of Accessibility and Accommodation, 105 Howarth, 253-879-3395. She will determine with you what accommodations are necessary and appropriate. All information and documentation is confidential. Classroom Emergency Response Guidance !Please review university emergency preparedness and response procedures posted at www.pugetsound.edu/emergency/. There is a link on the university home page. Familiarize yourself with hall exit doors and the designated gathering area for your class and laboratory buildings. If building evacuation becomes necessary (e.g. earthquake), meet your instructor at the designated gathering area so she/he can account for your presence. Then wait for further instructions. Do not return to the building or classroom until advised by a university emergency response representative. If confronted by an act of violence, be prepared to make quick decisions to protect your safety. Flee the area by running away from the source of danger if you can safely do so. If this is not possible, shelter in place by securing classroom or lab doors and windows, closing blinds, and turning off room lights. Lie on the floor out of sight and away from windows and doors. Place cell phones or pagers on vibrate so that you can receive messages quietly. Wait for further instructions. TIPS FOR SUCCESS IN BIOLOGY 111 Attend class. Attending class is the easiest way to know what material you will be responsible for on quizzes and exams. In addition, it presents timely opportunities to identify and voice any questions that you may have about the material being covered. If you fail to make a class, I recommend borrowing notes from more than one peer. After looking them over carefully, meet with me during office hours for any needed clarification. As stated in the course syllabus, there is no “make up” for missing class on the day of a quiz or exam. Commit a substantial amount of time. Plan to devote 5-8 hours a week outside of class time to the course. Approximately half of this time should be dedicated to preparing for upcoming lectures/labs/quizzes/exams and half the time should be dedicated to reviewing past lectures/ labs/quizzes/exams. The week prior to an exam, you will probably need to devote an additional 5-8 hours to studying. It can help to set aside regular time slots in their schedule to stay on top of class. Get the most from assigned readings. Lecture: when reading the indicated material prior to lecture, pay attention to the “big picture” and any unfamiliar terminology. The Pre-Class Assignment tool on Launchpad is useful for gauging your level of reading comprehension. There is no need to invest a lot of time in studying the text prior to class—we may not cover all the material in lecture. More importantly, this first reading will help set up an intellectual foundation that should enable you to follow the lecture with relative ease. After class, go back over the reading; this time focusing more deeply on the material that was covered in lecture. The In-Class Assignment and LearningCurve Activities on Launchpad are valuable is assessing your understanding of the material as well and include some simple application problems. The Quick Check questions embedded in the text are especially useful in prompting you to use apply material to a new situation, using your own words (similar to what most quiz/test questions). Laboratory: read the exercise carefully prior to lab. Highlight anything that is unclear and be sure to consult your lab partner, instructor or IA before forging ahead in the lab exercise. Being wellprepared for lab is the best way to ensure that you achieve experimental success and finish the exercise in a timely manner. Take notes. You should actively be taking notes during lecture and the first few minutes of lab. Also, when taking lecture notes, leave a fair amount of space to one side (~1/3rd of the page). Look over your notes soon after lecture and highlight any areas that seem unclear. When you reread the text assigned to the lecture, add relevant information from the text to that extra space. Merging lecture notes with reading notes creates a great resource for studying for quizzes and exams. Work with a study group. Meeting with classmates on a regular basis to discuss course material is a great way to work through challenging topics. In addition, it is an excellent way to identify what material is most difficult for you to communicate. Most graded work in this class involves short answer responses. While achieving a strong comprehension of your notes and the text is a great foundation, you also need to be able to accurately convey your knowledge with words. Not feeling comfortable with the language of biology can be a big obstacle. Study groups are the perfect setting to get practice at “speaking biology.” Find a group of peers who are willing to carefully listen to one another and provide helpful feedback as course material is discussed. Additional resources. If you’re struggling, bring your questions and/or concerns to office hours (or make an appointment if your schedule conflicts). Attend the study session held before each exam. Meet with biology tutors at the Center for Writing, Learning and Teaching or through Phi Sigma (hours to be announced). Biology 111B: Unity of Life Fall 2015 Schedule Instructor: Leslie Saucedo Office: TH257F Phone: 879-2788 Email: lsaucedo@ups.edu Texts: How Life Works, 1st ed., 2013, Morris et al. with Launchpad subscription A Student Handbook for Writing in Biology, 4th ed., 2013, Knisely Date Lecture Topic Text (Morris) Lab Mon. 8-31 Introduction to Biology Ch. 1 Wed. 9-2 The Molecules of Life I pp. C1-1 to C1-3, 2-1 to 2-8 Cells and Tissues Fri. 9-4 The Molecules of Life II pp. 2-9 to 2-19 ________________________________________________________________________________________________________ Mon. 9-7 No Class (Labor Day) Wed. 9-9 Nucleic Acids/DNA structure pp. 3-1 to 3-10 No labs Fri. 9-11 Transcription pp. 3-10 to 3-18 _________________________________________________________________________________________________________ Mon. 9-14 Quiz I (material from 8-31 to 9-11), Protein Structure pp. 4-1 to 4-8 Wed. 9-16 Translation I pp. 4-8 to 4-15 Biofilms I Fri. 9-18 Translation II/Protein Evolution pp. 4-15 to 4-19 _________________________________________________________________________________________________________ Mon. 9-21 Lipids, Membranes and Cell Walls pp. 5-1 to 5-12 Wed. 9-23 Quiz II (material from 9-14 to 9-21), pp. 5-12 to 5-23 Membranes Cell Compartments Fri. 9-25 Writing Workshop I: Abstracts and hypotheses Knisely pp. 2-3, 9-27, 79-80 __________________________________________________________________________________________________________ Date Lecture Topic Text (Morris) Lab Mon. 9-28 Exam I (material from 8-31 to 9-23) Wed. 9-30 Capturing and Using Energy I pp. 6-1 to 6-10 Biofilms II Fri. 10-2 Capturing and Using Energy II pp. 6-10 to 6-15 _________________________________________________________________________________________________________ Mon. 10-5 Cellular Respiration I pp. 7-1 to 7-10 Wed. 10-7 Cellular Respiration II pp. 7-10 to 7-20 Cell Respiration Fri. 10-9 Quiz III (material from 9-30 to 10-7), Photosynthesis I pp. 8-1 to 8-8 _________________________________________________________________________________________________________ Mon. 10-12 Photosynthesis II p. 8-9 to 8-20 Wed. 10-14 Cellular Communication I pp. C2-2 to 2-4, pp. 9-1 to 9-8 Photosynthesis Fri. 10-16 Cellular Communication II pp. 9-8 to 9-16 _________________________________________________________________________________________________________ Mon. 10-19 No Class (fall break) Wed. 10-21 Cell Form and Function Ch. 10 No labs Fri. 10-23 Quiz IV (material from 10-14 to 10-21), Mitosis pp. 11-1 to11-7 _________________________________________________________________________________________________________ Mon. 10-26 Cell Cycle Regulation pp. 11-14 to 11-21 Mitosis Wed. 10-28 Exam II (material from 9-30 to 10-26) & Fri. 10-30 Writing Workshop II: Results & Discussion Knisely 55-59, 76-78 Human Genetics I _________________________________________________________________________________________________________ Mon. 11-2 Meiosis pp. 11-7 to 11-14 Meiosis Wed. 11-4 DNA Replication pp. C3-2 to 3-4, 12-1 to 12-10 & Fri. 11-6 Genomes Ch. 13 Human Genetics II ___________________________________________________________________________________________________________ Date Lecture Topic Text (Morris) Lab Mon. 11-9 DNA Mutation and Repair Ch. 14 Genotype Wed. 11-11 Quiz V (material from 11-2 to 11-9), Genetic Variation Ch. 15 to Fri. 11-13 Mendelian Inheritance I pp. 16-1 to 16-10 Phenotype I ___________________________________________________________________________________________________________ Mon. 11-16 Mendelian Inheritance II pp 16-11 to 16-18 Genotype Wed. 11-18 Beyond Mendel Ch. 17 to Fri. 11-20 In class genetics problems Phenotype II ___________________________________________________________________________________________________________ Mon. 11-23 Exam III (material from 10-30 through 11-20) Wed. 11-25 No Class (travel day) No Labs Fri. 11-27 No Class (Thanksgiving holiday) ___________________________________________________________________________________________________________ Mon. 11-30 Complex Genetics Ch. 18 Bioethics Wed. 12-2 Genetic and Epigenetic Regulation I pp. 19-1 to 19-10 & Fri. 12-4 Genetic and Epigenetic Regulation II pp. 19-10 to 19-22 Lab Practical ___________________________________________________________________________________________________________ Mon. 12-7 Quiz VI (material from 11-30 to 12-4), Development pp. 20-1 to 20-5, 20-11 to 20-13 No Labs Wed. 12-9 Course Summary Friday, December 18th FINAL EXAM (comprehensive) 8:00-10:00 AM