Berkeley Dav i s i rv i n e los angeles MerceD riversiDe s a n ta B a r B a r a s a n ta c r u z san Diego san Francisco l aw r e n c e B e r k e l e y l aw r e n c e l i v e r M o r e ucTechnologytransFer A n n u A l r e p o rt 2007 Table of Contents Technology Transfer Advisory Committee Message from the Director 2 3 Technology Transfer Activity and Financial Information Introduction Part 1: The Campus Portfolios Technology Transfer Activity Invention Reporting Patent Activity Licensing and Related Activity Technology Transfer Income Total Income from Licensing Royalty and Fee Income Payments to Joint Holders Income Associated with Patent/Legal Expenses Technology Transfer Direct Expenses Legal and Other Direct Expenses Income Distributions Inventor Shares General Fund Share Research Allocation Share Income After Mandatory Distributions 4 4 4 4 6 8 10 10 10 11 11 12 12 13 13 13 13 13 Part 2: The DOE Laboratory-Managed Portfolios Invention Disclosure, Patenting, and Licensing Activity Financial Results 18 18 19 Technology Transfer Organization at UC UC Technology Transfer on the Web 20 20 2007 Technology Transfer Advisory Committee General oversight of the UC Technology Transfer Program is under the purview of the Technology Transfer Advisory Committee (TTAC). This standing committee is chaired by the Executive Vice President, Academic and Health Affairs and meets periodically to advise the UC President on technology transfer policy and guide the direction of the overall program. Keith Alley Executive Vice Chancellor & Provost, UCM Kathryn Atchison Vice Provost of Intellectual Property & Industrial Relations, UCLA Alan B. Bennett Associate Vice Chancellor for Research, UCD Carol Berman Contracts & Grants Director, DANR, UCOP Beth Burnside Vice Chancellor for Research, UCB Lawrence B. Coleman Vice Provost for Research, UCOP Arthur B. Ellis Vice Chancellor for Research, UCSD Sherylle Mills Englander Director, Office of Technology & Industrial Alliances, UCSB Cheryl A. Fragiadakis Department Head, Technology Transfer, LBNL Warren M. Gold Professor, Medicine, UCSF W. Rory Hume Provost & Executive Vice President, Academic & Health Affairs, UCOP Susanne L. Huttner Associate Vice Provost, Research and Director, Industry-University Cooperative Research Program, UCOP Charles F. Louis Vice Chancellor for Research, UCR Duncan McBranch Division Leader, Technology Transfer, LANL Karena McKinley Director, Industrial Partnerships & Commercialization, LLNL Norman J. Oppenheimer Professor, Pharmaceutical Chemistry, UCSF David G. Schetter Assistant Vice Chancellor, Research & Technology Alliances, UCI Hans Schöllhammer Professor, Global Economics & Management, UCLA P. Martin Simpson University Counsel, UCOP William T. Tucker Executive Director, Research Administration & Technology Transfer, UCOP A. Eugene Washington Executive Vice Chancellor & Provost, UCSF Fiscal Year 2007 Office of the President Executive Vice President, Academic and Health Affairs Office of Technology Transfer 1111 Franklin Street, 5th Floor Oakland, CA 94607-5200 Message from the Director The University of California’s technology transfer program plays a vital role in supporting UC’s world-class research enterprise and in translating promising discoveries into new products and businesses to bolster California’s economy. To realize the potential of UC’s inventions, the technology transfer program engages in numerous activities ranging from patenting and licensing to building relationships with industry and providing leadership on behalf of academic technology transfer at the state and national levels. Key to UC’s ability to successfully undertake such a broad range of activities is the division of labor between the UCOP Office of Technology Transfer (OTT) that coordinates technology transfer activities across the system, and campusbased technology transfer offices that are now almost entirely responsible for the program’s core patenting and licensing activities. OTT reaches out to industry and the investment community to foster collaborations and to increase awareness of opportunities to commercialize UC inventions. In FY07, OTT hosted its most successful systemwide technology transfer forum to date, which focused on nanotechnology. We also advanced UC’s research enterprise through collaborations with local and state organizations, supporting entrepreneurship and technology transfer education across the system and promoting business start-ups based on UC inventions. On the national level, UC has played a vital role in the ongoing discussions on patent reform and the impact of the Bayh-Dole Act on innovation and economic development. OTT and campus officials testified before Congress and participated in committee discussions to draft legislative language that addresses major issues of importance to the non-profit community to best serve our university mission. The technology transfer program performed well in FY07, again showing increased activity over the prior year. New inventions disclosures increased by 7.9%, resulting in UC’s portfolio of active inventions increasing by 10.1% to 8,272. UC added 331 new US patents to our portfolio, a 22.6% increase over the number of US patents added in FY06. At year end, UC owned 3,425 US patents and 3,757 foreign patents. Systemwide, we entered into 209 new utility license agreements, an increase of 6.1% over the number of such licenses in FY06. Total licensing income (which excludes any dispute resolutions settlements) increased 6.3% to $116.9 million in FY07 continuing a steady trend of increases since FY03. Overall, the technology transfer program this year expanded its contribution to UC’s mission of education, research, and public service, not only in terms of increased innovation and realization of public benefits from UC research, but also in undertaking initiatives to increase awareness of the contribution of UC’s research to the prosperity of the California economy. Sincerely, William Tucker Executive Director, Research Administration and Technology Transfer TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios introduction Activity and financial information in this Annual Report is divided into two parts. The UC Campus Portfolio section (pp. 4–17) presents results related to the patenting and licensing of inventions for the ten-campus system for the fiscal year ending June 30, 2007. This portfolio of inventions was managed by the Office of Technology Transfer (OTT) within the Office of the President (UCOP) and by nine campus-based licensing offices. These include the Office of Technology Licensing at UC Berkeley, InnovationAccess at UC Davis, the Office of Technology Alliances at UC Irvine, the Office of Intellectual Property Administration at UC Los Angeles, the Office of Technology Commercialization at UC Riverside, Technology Transfer and Intellectual Property Services at UC San Diego, the Office of Technology Management at UC San Francisco, the Office of Technology and Industry Alliances at UC Santa Barbara, and the Office for Management of Intellectual Properties at UC Santa Cruz. The DOE Laboratory-Managed Portfolio section (pp. 18–19) provides activity and financial information related to technology transfer at the two Department of Energy (DOE) Laboratories managed by the University. Information on the Laboratories is reported separately because certain aspects of technology transfer are different at the Laboratories as compared with the rest of the University. Among these differences is the reporting period which covers the fiscal year ending September 30, 2007. Part 1: The campus Portfolios TechnologY TransFer acTiviTY InventIon RepoRtInG During the twelve-month period ending June 30, 2007, a total of 1,411 inventions were disclosed by faculty and researchers at the ten UC campuses; an increase of 7.9% over the number of inventions reported in FY06 (Exhibit 1). ExhibiT 1 InventIonS RepoRteD 1500 1400 1,411 1300 1200 1,308 FY05 FY06 1,196 1100 1000 1,304 1,027 900 800 FY03 FY04 FY07 Half of this increase is accounted for by UC Irvine, where newly reported inventions increased by 50 from 141 in FY06 to 191 in FY07. Other campuses with large gains over this period include UC Santa Barbara (from 94 to 129), UC San Diego (from 310 to 333), and UC Davis (from 158 to 180). The campus distribution of newly reported inventions for FY07 is shown in Exhibit 2. ExhibiT 2 InventIon DISCLoSUReS BY CAMpUS* Year Ended June 30, 2007 UCSF 142 UCB 133 As of June 30, 2007, the systemwide invention portfolio was comprised of 8,272 active inventions. The size of each campus invention portfolio is indicated in the exhibit below. ExhibiT 3 CAMpUS InventIon poRtFoLIoS* UCD 180 UCI 191 UCLA 267 UCM 12 UCR 31 UCSB 129 UCSC 16 UCSD 333 *Inventions having inventors from more than one campus are counted multiple times, once for each campus with an inventor. Year Ended June 30, 2007 UCB 924 UCD 875 UCI 708 UCLA 1,401 UCM 13 UCR 209 UCSB 572 UCSC 120 UCSD 2,180 UCSF 1,378 *Inventions associated with inventors from more than one campus are reported multiple times in this exhibit. TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios pAtent ACtIvItY The University of California has received more patents than any other university in the world. A patent is a form of intellectual property protection granted by the US or a foreign government that gives the patent holder the right to exclude others from making, using, or selling the patented invention for a defined period of time, generally twenty years from the date the patent application is first filed. Both US and foreign patent rights often must be pursued for an invention in order to maximize the likelihood of successful commercialization. Systemwide patent activity for FY07 is presented in Exhibit 4. Acquiring adequate patent coverage for all aspects of a new technology may require more than one patent filing for a given invention. Such secondary filings frequently lead to the issuance of multiple patents related to a single initial invention. Often, several years will elapse between a filing and patent issuance. The number of first filings declined 9.8% compared to 714 in FY06, while the number of secondary filings increased 20.0% from 470 in FY06. Foreign patents issued declined by 35.0% from 586 in FY06. Exhibit 5 shows the number of US patents issued to the University in the past five years. ExhibiT 4 ExhibiT 5 pAtent ACtIvItY* US pAtentS ISSUeD to UC Year Ended June 30, 2007 U.S. Applications Filed First Filings Secondary Filings Total 350 644 564 1,208 300 First Foreign Filings* 315 200 US Patents Issued 331 150 Foreign Patents Issued 381 100 *An invention is counted only one time in the first foreign filings category regardless of the number of countries in which foreign patent protection is sought. 323 270 250 331 310 270 50 0 FY03 FY04 FY05 FY06 FY07 At the end of FY07, there were 3,425 US and 3,757 foreign patents in the systemwide portfolio (Exhibit 6). The total number of foreign-filed patents continues to increase relative to total number of US-filed patents, having first overtaken the total number of US-filed patents in FY06. This trend may be an indication of the increasingly global nature of technology licensing. The number of US patents in each campus portfolio is presented in Exhibit 7. Because of the substantial lag time between invention disclosure/ filing and patent issuance, UC Merced, which received its first invention disclosure in FY06, has not yet had a patent issued for its inventions. 2000 Year Ended June 30, 2007 562 UCD 394 UCI 220 UCLA 498 UCM 0 UCR 82 ExhibiT 6 UCSB 302 totAL UC pAtent poRtFoLIo UCSC 61 UCSD 566 UCSF 755 3500 2500 CAMpUS US pAtent poRtFoLIoS* UCB 4000 3,757 3,692 3,275 3000 ExhibiT 7 3,024 2,753 3,168 3,316 3,425 * Patents associated with inventors from more than one campus are reported multiple times in this exhibit. 2,837 2,364 1500 1000 500 0 FY03 U.S. FY04 FY05 FY06 FY07 Foreign TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios LICenSInG AnD ReLAteD ACtIvItY A license agreement grants a licensee access to a University invention in exchange for the licensee’s commitment to further develop and commercialize the invention. Utility licenses generally cover useful processes, machines, manufactured items, or compositions of matter protected by utility patents and are likely to be licensed exclusively. In contrast, plant licenses cover sexually and asexually reproduced plant varieties and most are licensed non-exclusively to multiple growers and distributors worldwide. The provisions of the license define the rights and responsibilities of the two parties. In the typical utility license agreement, the licensee is granted access to an early stage invention that is protected by a University patent. In exchange, the licensee makes a commitment to commercialize the invention and to pay the University agreed-upon fees, including reimbursement of patent expenses and royalty payments when products reach the marketplace. The specific terms of the agreement are determined through a complex negotiation process. Prior to the execution of a license, certain shorter-term agreements are sometimes executed. A secrecy agreement is used in conjunction with marketing and affords a potential licensee access to confidential information that assists the company in determining if it has an interest in pursuing a license for a given technology. In FY07, the University entered into 768 secrecy agreements. A letter agreement generally is used to confirm a company’s intent to negotiate a license and often commits a company to pay certain fees or patent costs while negotiations are underway. Option agreements are similar in scope to license agreements and protect a licensee’s interest in an invention while more in-depth technical or marketing research is performed. In FY07, UC entered into 440 licenses and related technology transfer agreements. As indicated in Exhibit 8, these included 209 utility license agreements, 73 plant license agreements, 22 option agreements, and 136 letter agreements. ExhibiT 8 LICenSInG ACtIvItY Year Ended June 30, 2007 Agreements Executed Letters Options Utility Licenses Plant Licenses 136 22 209 73 Total Active Licenses Utility Licenses Plant Licenses 1,315 504 At the close of the fiscal year, the systemwide portfolio totaled 1,819 licenses, an increase of 3.9% over the total at the close of FY06. In managing these agreements, the University must collect monies when due and monitor progress to ensure that the licensees exercise due diligence in developing inventions toward commercial application. ExhibiT 9 totAL UtILItY LICenSeS 1400 1,315 1200 1,114 1000 800 902 1,200 983 600 400 ExhibiT 11 200 totAL UtILItY LICenSeS BY CAMpUS* Year Ended June 30, 2007 0 FY03 FY04 FY05 FY06 FY07 ExhibiT 10 totAL pLAnt LICenSeS 600 550 400 454 473 504 488 200 0 UC continues to work with our licensees around the world to explore opportunities for gaining intellectual property protection and commercializing selected strawberry and other plant cultivars in countries where such intellectual property rights have not previously been available. In regard to the distribution of plant licenses among the campuses, the Davis campus has 383 plant licenses in its portfolio, Riverside has 120, and Berkeley has 1. Exhibit 11 shows the number of utility license agreements associated with each campus. FY03 FY04 FY05 FY06 FY07 UCB 257 UCD 100 UCI 79 UCLA 189 UCM 1 UCR 19 UCSB 43 UCSC 10 UCSD 305 UCSF 356 *Licenses associated with inventions that have inventors from more than one campus are reported multiple times in this exhibit. Exhibits 9 and 10 show the five year trend in the size of the portfolio of UC utility and plant licenses. Each year some agreements expire or are terminated. In general, the total number of active utility agreements has continued to rise due to increasing licensing activity throughout the system. In the plant area, a wide variety of fruits, vegetables and grasses were the subject of 504 agreements. TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios TechnologY TransFer income totAL InCoMe FRoM LICenSInG Total income from licensing—the income the University receives from its technology agreements with industry—was $116.9 million in FY07 (Exhibit 12). This FY07 total licensing income represents a 6.3% increase from FY06 if one excludes the $100 million received in FY06 for settlement of the bovine growth hormone litigation. There are two components of total licensing income. The royalty and fee income component includes: agreement issue fees, maintenance fees, and other “milestone” payments received on specific dates or at specific points in the product development process. These payments encourage companies to diligently pursue product commercialization. Generally, earned royalties account for the largest portion of royalty and fee income and are received once products and processes using University inventions reach the marketplace. Reimbursements, the second component of total licensing income, represent the recovery of patent and legal expenses. increased its contribution by $1.2 million (37.3%). While the contributions shown in Exhibit 13 only involve income arising from University inventions, in FY07 UC Santa Barbara also received $1.3 million from licenses involving donated patents covering non-University inventions. ExhibiT 13 totAL LICenSInG InCoMe BY CAMpUS* Year Ended June 30, 2007 (Thousands) ExhibiT 12 totAL LICenSInG InCoMe* $109.6 $93.2 16.7 16.5 $81.3 13.9 92.9 93.5 14.3 79.3 100 80 60 $110.0 $116.9 19.3 97.6 67.0 20 FY03 FY04 FY05 FY06 FY07 Patent/legal reimbursement revenue Royalty & fee income * The total licensing income reported for FY06 ($110 million) does not include the upfront payment of $100 million from the settlement of litigation involving bovine growth hormone. Exhibit 13 shows the amount each campus contributed to FY07 total licensing income. For the first time our newest campus, UC Merced, contributed to this income. UC Los Angeles increased its contribution by $3.2 million (14.4%) over its FY06 contribution, while UC Santa Barbara 0 UCD $9,217 UCI $6,716 UCLA $25,294 UCM $59 UCR $1,408 UCSB $4,590 UCSC $440 UCSD $25,696 UCSF $33,226 $2,852 * Total licensing income consists of two components: royalty and fee income and patent/legal reimbursements. ** Revenues primarily from a portfolio of OTT-managed DOE Laboratory inventions, most disclosed prior to the establishment of the Laboratory-based licensing offices. RoYALtY AnD Fee InCoMe 40 0 $7,388 Other** (Millions) $120 UCB Royalty and fee income in FY07 was $97.6 million. This income derived from 1,592 inventions. As compared with FY06, royalties and fees increased by $4.1 million when excluding a $100 million litigation settlement received in FY06. In FY07, $1,167,318 was realized from the sale of equity previously acquired under 8 license agreements. As a result of these transactions and the execution of 13 licenses in FY07 that included equity as a partial consideration, at the end of the fiscal year the University held equity related to technology transfer activities in 92 companies. Income from the top five commercialized UC inventions (i.e. inventions that had reached the marketplace and were generating royalty and fee income) contributed $47.7 million in FY07, accounting for 48.9% of total royalty and fee income (Exhibit 14). The top twenty-five inventions collectively accounted for $73.9 million or 75.7% of total royalties and fees. Inventions appearing on this list for the first time include Albion Strawberry, Bovine Growth Hormone, Comparative Genomic Hybridization, Efficient GaN-based LEDs, and Genomic Microarrays. ExhibiT 14 UC top-eARnInG InventIonS* Year Ended June 30, 2007 (Thousands) invention (campus, Year disclosed) Hepatitis-B Vaccine (SF, 1979 and 1981) $14,656 Treatment of Intracranial Aneurysms (LA, 1989) $11,122 Egf Receptor Antibodies (SD, 1983) $8,700 Interstitial Cystitis Therapy (SD, 1980) $7,160 Bovine Growth Hormone (SF, 1980) $6,083 Subtotal (top Five Inventions) $47,721 Biodegradable Implant Coils (LA, 1998) $4,071 Dynamic Skin Cooling Device (IR, 1993) $3,231 Camarosa Strawberry (DA, 1992) $1,942 Chromosome Painting (LLNL, 1985) $1,715 Nicotine Patch (LA, 1984) $1,653 Energy Transfer Primers (BK, 1994) $1,451 Firefly Luciferase (SD, 1984) $1,413 Genomic Microarrays (SF, 1995) $1,176 Feline AIDS Virus Diagnostic (DA, 1986) $1,174 Comparative Genomic Hybridization (SF, 1992) $1,154 Aids for Learning Disabled (SF, 1994) $1,094 Liposome Storage Method (DA, 1984) $1,077 Ventana Strawberry (DA, 2001) $828 Laser/Water Atomic Microscope (SB, 1989) $752 Fluorescent Dyes-Calcium (BK, 1984) $736 Albion Strawberry (DA, 2004) $708 Cochlear Implants (SF, 1979) $672 Universal Oligonucleotide Spacer (BK, 1996) $544 Magnetic Resonance Imaging (SF, 1976) $403 Efficient GaN-based LEDs (SB, 2004) $400 Total income (Top 25 inventions) $73,915 Total income (all inventions) $97,594 % of Total from Top 5 inventions 48.9% % of Total from Top 25 inventions 75.7% *This list is limited to revenue-generating inventions that have been commercialized. pAYMentS to JoInt HoLDeRS When an invention results from collaboration between UC and non-UC researchers, multiple entities may become joint holders of the invention-related patents. In these instances, UC often negotiates interinstitutional agreements to establish which entity will manage patenting and licensing. In FY07, 272 of 1,411 new disclosures (19.3%) included non-UC inventors and 61 new interinstitutional agreements were signed, a 23.8% decrease over FY06. In FY07, $4.8 million was redistributed to other entities for inventions covered by interinstitutional and other income-sharing agreements. For financial reporting purposes, these monies are treated as an offset to income. As is seen in Exhibit 15, these redistributions have been declining in recent years when one excludes the $7.9 million payment in FY06 and $0.5 million payment in FY07 for settlement of litigation involving bovine growth hormone. ExhibiT 15 pAYMentS to JoInt HoLDeRS* (Millions) $10 8 6 $5.9 $5.0 $5.4 $5.6 $4.3 4 2 0 FY03 FY04 FY05 FY06 FY07 * The payments to joint holders reported in this exhibit for FY06 ($5.6 million) and FY07 ($4.3 million) do not include payments of $7.9 million in FY06 and $0.5 million in FY07 for the settlement of litigation involving bovine growth hormone. InCoMe ASSoCIAteD wItH pAtent/LeGAL expenSeS Because inventions are highly technical, the University uses specialized outside attorneys to draft and secure patent protection both in the U.S. and abroad. Obtaining a licensee’s commitment to reimburse these costs is a high priority objective of license negotiations, and reimbursements, therefore, are considered to be part of total licensing revenue. In FY07, the University received $19.3 million in licensing income from patent/legal expense reimbursements. TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios TechnologY TransFer exPenses LeGAL AnD otHeR DIReCt expenSeS Legal and other direct expenses totaled $35.1 million in FY07 (Exhibit 16). Most technology transfer legal expenses are associated with patent prosecution defined as payments to outside counsel for drafting patent applications as well as other costs for securing and maintaining patent protection for University inventions. The extent of reimbursement of legal and other direct expenses is a negotiated term of a license agreement and not all agreements commit the licensee to reimburse the University for these costs. In FY07, reimbursements of legal expenses totaled $19.3 million, resulting in net legal expenses of $15.8 million (Exhibit 16). Exhibit 17 provides a breakdown of FY07 net legal expenses (i.e., legal expenses after reimbursements) by category. Patent prosecution activities accounted for $10.6 million of the $15.8 million in net legal expenditures. Interference and infringement activities, which accounted for 55% of net legal expenses in FY06, declined to 29% in FY07. The relatively large interference and infringement percentage in FY06 reflects expenses associated with the settlement of infringement litigation involving bovine growth hormone. ExhibiT 17 net LeGAL expenSeS Year Ended June 30, 2007 Legal Defense 1% Other 2% ExhibiT 16 Interference & Infringement 29% LeGAL expenSeS* (Millions) $40 $35.1 $34.4 30 $27.9 $28.7 Patent Prosecution 68% $26.9 20 10 $13.6 $14.8 $17.7 $15.8 $10.4 0 FY03 FY04 FY05 FY06 FY07 Gross legal expenses Net legal expenses * The gross and net legal expenses reported for FY06 do not include $16.2 million in legal expenses for the settlement of litigation involving bovine growth hormone. It is anticipated that University licensing personnel will continue to be successful in negotiating reimbursement of a substantial amount of patent costs. Nonetheless, it is expected that there will continue to be significant legal expenses associated with patenting and litigation as the technology transfer program matures, patent activities continue to accelerate, and relationships with inventors, sponsors and licensees become increasingly complex. income disTriBUTions InventoR SHAReS The income derived from royalties and fees, less the sum of payments to joint holders and less net legal and direct expenses, is distributed in various shares as required under University and campus policies. In FY07, income distributions totaled $77.0 million, distributed as shown in Exhibit 18. ExhibiT 18 InCoMe DIStRIBUtIonS* (Millions) $80 60 40 $69.8 $59.4 $47.5 $77.6 $77.0 33.0 30.0 31.0 25.5 11.0 32.4 25.3 3.6 8.2 28.2 31.3 35.6 20 0 0.5** FY03 10.1 0.4** FY04 0.4** FY05 12.6 0.7** FY06 10.0 1.4** FY07 Income after mandatory distributions Inventor shares **Research allocation share General fund share * The distributions reported for FY06 do not include a general fund distribution of $10.5 million, inventor share distributions of $29.1 million, nor income after mandatory distributions of $36.2 million related to the settlement of litigation involving bovine growth hormone. The University Patent Policy grants inventors the right to receive a portion of net income accruing to individual inventions. In FY07, 1,638 inventors received a total of $35.6 million. Under current policy, inventors receive 35% of net invention income. Inventor shares are calculated based on invention income and expense activity through the close of the prior fiscal year. Thus, most of the inventor shares distributed in FY07 were calculated based on invention financial activity through June 30, 2006. Trends related to the amount of inventor share payments are reflected in Exhibit 18. GeneRAL FUnD SHARe The portion of University technology transfer income allocated to the UC General Fund totaled $10.0 million in FY07 (Exhibit 18, above). The General Fund share is equal to 25% of the amount remaining after deducting payments to joint holders, net expenses, and inventor share payments from royalty and fee income. ReSeARCH ALLoCAtIon SHARe The current Patent Policy requires that 15% of net royalty and fee income from each invention be designated for research-related purposes on the inventor’s campus or Laboratory. These monies are used in accordance with plans developed at each campus and Laboratory. The research allocation, which is computed based on inventions disclosed on or after October 1, 1997, totaled $1.4 million in FY07 (Exhibit 18). InCoMe AFteR MAnDAtoRY DIStRIBUtIonS All income derived from royalties and fees remaining after deductions for payments to joint holders, net legal and direct expenses, and other distributions, is distributed to the campuses subject to certain other campus-specific debits and credits for patent-related activities (not shown). This category combines expenditures that in prior Annual Reports were reported separately as “Operating Expense” and “Campus Share” distributions. Income after mandatory distributions totaled $30.0 million in FY07 (Exhibit 18). TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios ExhibiT 19 SYSteMwIDe teCHnoLoGY tRAnSFeR ACtIvItY FY03 – FY07* Year Ended June 30, 2007 Fiscal Year comparisons FY03 FY04 FY05 FY06 FY07 % change (FY06-FY07) Invention Disclosure Inventions Reported Total Invention Portfolio 1,027 5,948 1,196 6,618 1,304 7,395 1,308 7,513 1,411 8,272 7.9% 10.1% Patent Prosecution US Applications Filed First Filings Secondary Filings Total US Patents Issued Total Active US Patents 490 384 874 323 2,753 515 450 965 270 3,024 601 429 1,030 310 3,275 714 470 1,184 270 3,316 644 564 1,208 331 3,425 -9.8% 20.0% 2.0% 22.6% 3.3% 230 2,364 243 2,837 284 3,168 361 3,692 315 3,757 -12.7% 1.8% 21 131 56 32 145 81 22 186 57 29 197 115 22 209 73 -24.1% 6.1% -36.5% 62 902 454 53 983 473 52 1,114 488 61 1,200 550 69 1,315 504 13.1% 9.6% -8.4% First Foreign Filings Total Active Foreign Patents Licensing Agreements Issued Options Utility Licenses Plant Licenses Total Active Agreements Options Utility Licenses Plant Licenses Exhibit 19 only reports activity governed by the UC Patent Policy. It does not include copyright and material transfer agreement activity that also is carried out by campus-based technology transfer offices *Activity related to the invention portfolio managed by the nine campus-based licensing offices and OTT on behalf of the ten UC campuses. Activity related to a small number of DOE Laboratory inventions managed at OTT also is reflected in these figures. See pp. 18-19 for activity pertaining to the operation of the DOE Laboratorybased technology transfer offices. ExhibiT 20 SYSteMwIDe FInAnCIAL ACtIvItY FY03-FY07 Year Ended June 30, 2007 (Thousands) Fiscal Year comparisons FY03 FY04 FY05 FY06 FY07 % change (FY06-FY07) Income from Royalties and Fees Less: Payments to Joint Holders Adjusted Gross Income (A) $67,019 (5,854) 61,165 $79,265 (4,990) 74,275 $92,902 (5,403) 87,499 $193,500 (13,464) 180,036 $97,594 (4,798) 92,796 -50% -64% -48% Legal and Other Direct Expenses Less: Reimbursements Net Legal Expenses (B) (27,929) 14,300 (13,629) (28,761) 13,916 (14,845) (34,393) 16,707 (17,686) (43,136) 16,545 (26,591) (35,087) 19,292 (15,795) -19% 17% -41% Income Available for Distribution (A+B) 47,536 59,430 69,813 153,445 77,001 -50% Income Distributions Inventor Shares (C) Research Allocation Share (D) General Fund Share (E) Income After Mandatory Distributions (F) Total Income Distributions (C+D+E+F) 32,357 534 3,608 11,037 47,536 25,310 359 8,214 25,547 59,430 28,228 422 10,138 31,025 69,813 60,471 722 23,078 69,174 153,445 35,562 1,380 10,045 30,014 77,001 -41% 91% -56% -57% -50% Exhibit 20 only reports financial activity governed by the UC Patent Policy. Campus-based technology transfer offices also generate income through copyright licenses, material transfer agreements and through research support committed in conjunction with technology transfer activities. This income is not included in this report. TechnologY TransFer acTiviTY and Financial inFormaTion Part 1: The Systemwide/Campus Portfolios ExhibiT 21 FY07 CAMpUS teCHnoLoGY tRAnSFeR ACtIvItY Year Ended June 30, 2007 UcB Ucd Uci Ucla Ucm Ucr UcsB invention disclosure Inventions Reported Total Invention Portfolio 133 924 180 875 191 708 267 1,401 12 13 31 209 Patent Prosecution US Applications Filed First Filings Secondary Filings Total US Patents Issued Total Active US Patents 60 62 122 53 562 80 54 134 45 394 89 66 155 30 220 129 164 293 42 498 3 1 4 0 0 34 401 30 522 24 331 87 529 3 44 0 3 13 62 2 11 0 17 257 1 7 100 383 4 79 0 First Foreign Filings Total Active Foreign Patents licensing Agreements Issued Options Utility Licenses Plant Licenses Total Active Agreements Options Utility Licenses Plant Licenses Ucsc Ucsd UcsF 129 572 16 120 333 2,180 142 1,378 22 5 27 10 82 81 75 156 25 302 4 15 19 9 61 142 65 207 64 566 43 68 111 62 755 1 0 6 119 43 83 2 12 60 764 33 1,008 3 40 0 0 0 0 4 5 11 6 12 0 0 0 0 2 56 0 0 35 0 11 189 0 0 1 0 6 19 120 12 43 0 1 10 0 6 305 0 8 356 0 Exhibit 21 only reports activity governed by the UC Patent Policy. It does not include copyright and material transfer agreement activity which also is carried out by campus-based technology transfer offices. Note: A number of inventions involve inventors from multiple UC campuses. Activity statistics for these inventions are reported multiple times, once for each campus involved. Thus, for any given measure of activity, the sum of individual campus numbers may be greater than the systemwide totals reported elsewhere in this report. ExhibiT 22 FY07 CAMpUS FInAnCIAL ACtIvItY* Year Ended June 30, 2007 (Thousands) Income from Royalties and Fees Less: Payments to Joint Holders Adjusted Gross Income (A) Legal and Other Direct Expenses Less: Reimbursements Net Legal Expenses (B) Income Available for Distribution (A+B) UcB Ucd Uci Ucla Ucm Ucr UcsB Ucsc $5,056 $8,090 $5,191 (23) (9) (110) 5,033 8,081 (3,528) (3,103) Ucsd UcsF $20,911 $50 $762 $2,951 $100 (15) 0 (12) (4) (1) (119) (4,505) 5,081 20,896 50 750 2,947 99 21,303 25,905 (2,487) (9,847) (33) (804) (2,044) (279) (6,542) (5,552) $21,423 $30,410 2,332 1,127 1,525 4,383 9 646 1,639 340 4,273 2,816 (1,195) (1,976) (962) (5,464) (24) (159) (405) 61 (2,268) (2,736) 3,838 6,105 4,119 15,432 26 591 2,542 160 19,035 23,169 1,763 3,227 3,432 6,911 0 313 769 18 8,587 9,904 Income Distributions Inventor Shares (C) Research Allocation Share (D) 55 87 93 102 0 6 94 6 743 194 519 720 172 2,127 7 70 443 35 2,612 3,316 Income After Mandatory Distributions (F) 1,501 2,071 422 6,292 19 203 1,236 101 7,093 9,755 Total Income Distributions (C+D+E+F) 6,105 4,119 15,432 26 591 2,542 160 19,035 23,169 General Fund Share (E) 3,838 *Exhibit 22 only reports financial activity governed by the UC Patent Policy. Campus-based technology transfer offices also generate income through copyright licenses and material transfer that are not covered by the UC Patent Policy. This income is not included in this report. TechnologY TransFer acTiviTY and Financial inFormaTion Part 2: The DOE Laboratory-managed Portfolios Part 2: The doe laboratory-managed Portfolios Background Since 1988, technology transfer for the UC-managed U.S. Department of Energy (DOE) Laboratories has been under the purview of Laboratory-based offices. In this fiscal year, we will be reporting on technology transfer activity at Lawrence Berkeley National Laboratory (LBNL) and Lawrence Livermore National Laboratory (LLNL). The technology transfer program at Los Alamos National Laboratory (LANL) will not be covered this year as LANL is no longer under direct UC management. The licensing function at the Laboratories is managed within the context of larger departments responsible for fostering a variety of partnerships with industry: LBNL’s Technology Transfer Office and LLNL’s Industrial Partnerships and Commercialization Office. In addition to patent licensing, these offices direct substantial resources toward the licensing of software and the negotiation of Cooperative Research and Development Agreements (CRADAs), technical assistance and other agreements with industry. Although these DOE Laboratory offices manage most Laboratory inventions, OTT oversees a small portfolio of Laboratory inventions. Most of these cases have coinventors from the UC campuses. Certain aspects of technology transfer processes differ at the DOE offices as compared with OTT and the campuses. For example, after an invention is disclosed and a determination is made to pursue a license, there are some cases where the laboratory may be able to elect title to an invention on behalf of the University under the federal Bayh-Dole legislation, just as a campus does. In other cases, however, there must be a special request to DOE to enable The Regents to retain or be assigned title to the invention. Requests to assert copyright in software also must be made to DOE. In addition, whereas OTT and campus offices contract with attorneys at outside law firms for all of their patent prosecution activity, the Laboratories manage most US patent filings internally through their own legal departments and contract out only for selected matters, particularly foreign prosecution. In addition, the fiscal year at the Laboratory offices ends September 30th in contrast to the June 30th end date for the fiscal year at OTT and the campus offices. Information in this section pertains to the activities of the technology transfer offices of the Laboratories unless noted otherwise. InventIon DISCLoSURe, pAtentInG, AnD LICenSInG ACtIvItY In FY07, DOE Laboratory researchers disclosed 287 inventions and filed a total of 165 US patent applications. 87 US patents issued on DOE inventions. The Laboratories completed 25 new options and licenses for patentable inventions and tangible research products (TRPs) in FY07, bringing the total number of active license and option agreements to 169 at the close of the fiscal year (Exhibit 23). Licensing of other types of intellectual property (e.g., copyrighted software) also represents a significant additional element of current licensing activity. FInAnCIAL ReSULtS ExhibiT 23 pAtentInG AnD LICenSInG ACtIvItY: Doe LABoRAtoRY oFFICeS Year Ended Sept. 30, 2007 lBnl llnl Total 126 161 287 67 7 74 64 27 91 131 34 165 25 29 62 28 87 57 201 2 3 480 5 15 681 7 18 8 61 8 92 16 153 Disclosure and Prosecution* Inventions Reported US Applications Filed First Filings Secondary Filings Total US Patents Issued First Foreign Filings Marketing and Licensing New Agreements Issued Secrecy Option License Total Active Agreements Option License The DOE Laboratory-managed portfolios generated a total of $7.8 million in income during FY07, an increase of 10.6% over the prior year (excluding LANL). Patent income for the Labs increased 12.1% as compared with FY06, while copyright income increased by 1.1% (Exhibit 24). Information on DOE Laboratory patenting and licensing expenses is not provided in this report. Patent expenses are allowable costs under the University’s current contract with DOE and are not readily separable from other expenses of the legal departments. Similarly, operating expenses related to the licensing function are not readily separable from other expenses of the technology transfer departments. Finally, income generated by the DOE Laboratories is not subject to the General Fund share assessment. Inventor share payments of $2.7 million included $275 thousand paid to authors of software. These payments were based on financial activity through September 30, 2007. ExhibiT 24 FInAnCIAL ACtIvItY: Doe LABoRAtoRY oFFICeS* Year ended September 30, 2007 (Thousands) FISCAL YeAR CoMpARISonS (excluding LANL) Disclosure and Prosecution* Inventions Reported US Applications Filed First Filings Secondary Filings Total US Patents Issued First Foreign Filings Marketing and Licensing New Agreements Issued Secrecy Option License Total Active Agreements Option License FY06 FY07 %change 238 287 21% 113 59 172 131 34 165 16% -42% -4% 98 41 87 57 -11% 39% 192 3 23 681 7 18 255% 133% -22% 9 152 16 153 78% 1% Income from Royalties and Fees Patents and TRPs Copyrights/Software Total lBnl llnl Total $2,502 $716 $3,218 $4,358 $231 $4,589 $6,860 $947 $7,807 $796 $169 $965 $1,619 $106 $1,725 $2,415 $275 $2,690 Inventor /Author Shares Paid Patents and TRPs Copyrights/Software Total FISCAL YeAR CoMpARISonS (excluding LANL) (Thousands) Patents and TRPs Copyrights/Software Total Inventor/Author Shares Paid Inv./Aut. Shares Paid (copy./soft.) Total FY06 FY07 %change $6,121 $936 $7,057 $6,860 $947 $7,807 12% 1% 11% $2,152 $263 $2,415 $2,415 $275 $2,690 12% 5% 11% *In addition to income reported in this table, the OTT-managed DOE portfolio collectively generated $2,518,226 in FY07 royalty and fee income, including $404,993 for LBNL and $2,113,233 for LLNL inventions. TechnologY TransFer organizaTion aT Uc The UC Technology Transfer program operates under a model of distributed responsibilities and authorities that balances activities carried out at the central Office of Technology Transfer (OTT) with those at the individual UC campuses and UC-managed DOE Laboratories. Under this approach, campuses and Laboratories develop and shape technology licensing programs to fit their unique needs as put forth in memoranda of understanding negotiated with the UC Office of the President (UCOP). In all instances, OTT retains responsibility for certain functions, such as policy development and guidance, legal oversight, legislative review, information management, and a variety of other services in support of the overall program. Internet links to UC OTT, campus and Laboratory-based technology transfer offices are provided below. UC technology transfer on the web UC Office of the President: Office of Technology Transfer (OTT) http://www.ucop.edu/ott UC Berkeley: Office of Intellectual Property & Industry Research Alliances (IPIRA) http://ipira.berkeley.edu UC Davis: UC Davis InnovationAccess http://www.innovationaccess.ucdavis.edu UC Irvine: Office of Technology Alliances (OTA) http://www.ota.uci.edu UC Los Angeles: Office of Intellectual Property & Industry Sponsored Research (OIP-ISR) http://www.research.ucla.edu/oipa UC Merced: Office of Technology Transfer (OTT) http://research.ucmerced.edu UC Riverside: Office of Technology Commercialization (OTC) http://www.ora.ucr.edu/ip UC Santa Barbara: Office of Technology & Industry Alliances (TIA) http://research.ucsb.edu/tech_transfer UC Santa Cruz: Office for Management of Intellectual Property (OMIP) http://research.ucsc.edu/intel_prop.html UC San Diego: Technology Transfer & Intellectual Property Services (TechTIPS) http://invent.ucsd.edu UC San Francisco: Office of Technology Management (OTM) http://www.otm.ucsf.edu Lawrence Berkeley National Laboratory: Technology Transfer Department (TTD) http://www.lbl.gov/Tech-Transfer Lawrence Livermore National Laboratory: Industrial Partnerships Office (IPO) https://ipo.llnl.gov/ Industry-University Cooperative Research Program (IUCRP) http://ucdiscoverygrant.org 0 university of california office of technolgy transfer 1111 Franklin street, 5th Floor oakland, ca 94607-5200