MSC MED IC INA L N ATURA L PR OD U C TS A N D PH YTOC H EMISTRY Programme Handbook 2015/2016 Disclaimer Every effort has been made to ensure that the information in this Handbook is correct at the time of going to press (September 2015). UCL reserves the right to make amendments to the information contained in this Handbook as a result of unforeseen events or circumstances beyond UCL's control or if deemed reasonably necessary by UCL. This handbook is deemed to be the definitive version of information for all students on this taught programme of study. In the event that amendments are made, UCL shall take reasonable steps to notify students as soon as possible. 11/09/2015. Version 1 1 Table of Contents 1. General Information................................................................................................... 5 PROGRAMME HANDBOOK ........................................................................................................ 5 1.2 PROGRAMME STAFF ........................................................................................................ 6 Programme Team ............................................................................................................................ 6 Programme Director ........................................................................................................................ 6 Deputy Programme Director ........................................................................................................... 6 Academic Staff ................................................................................................................................. 6 1.3 PROGRAMME ADMINISTRATION ..................................................................................... 7 2. Programme Information ............................................................................................. 9 2.1 2.2 2.3 2.4 2.5 2.6 3. PROGRAMME DETAILS..................................................................................................... 9 THE MSc MEDICINAL NATURAL PRODUCTS AND PHYTOCHEMISTRY PROGRAMME ...........10 MASTER’S LEVEL DESCRIPTORS .......................................................................................10 PROGRAMME STRUCTURE ..............................................................................................11 LEARNING AND TEACHING METHODS .............................................................................13 CAREER RELEVANCE AND EMPLOYABILITY .......................................................................13 Modules....................................................................................................................15 3.1 MODULE CHOICE ............................................................................................................15 3.2 MODULE OUTLINES ........................................................................................................15 PHAYG019 MEDICINAL NATURAL PRODUCTS .......................................................................... 16 PHAYG024 ANALYTICAL TECHNIQUES IN PHYTOCHEMISTRY ................................................... 18 PHAYG026 NATURAL PRODUCT DISCOVERY ............................................................................ 20 PHAYG035 BIODIVERSITY AND MEDICINES .............................................................................. 22 4. Research Project .......................................................................................................24 4.1 5. OVERVIEW .....................................................................................................................24 Assessment and Regulations ....................................................................................25 5.1 PROGRAMME REGULATIONS ..........................................................................................25 Coursework.................................................................................................................................... 25 Examinations ................................................................................................................................. 25 Resits ................................................................................................. Error! Bookmark not defined. Final Degree Mark ............................................................................. Error! Bookmark not defined. Merit .................................................................................................. Error! Bookmark not defined. Distinction.......................................................................................... Error! Bookmark not defined. 5.2 ASSESSMENT ..................................................................................................................26 PHAYG019 MEDICINAL NATURAL PRODUCTS .......................................................................... 26 PHAYG024 ANALYTICAL TECHNIQUES IN PHYTOCHEMISTRY ................................................... 27 PHAYG026 NATURAL PRODUCT DISCOVERY ............................................................................ 27 PHAYG035 BIODIVERSITY AND MEDICINES .............................................................................. 27 5.3 SCHEME OF AWARD .......................................................................................................29 PHAYG019 Medicinal Natural Products (30 credits)................................................................ 29 PHAYG024 Analytical Techniques in Phytochemistry (30 credits) .......................................... 29 PHAYG026 Natural Product Discovery (30 credits) ................................................................. 29 PHAYG035 Biodiversity and Medicines (30 credits) ................................................................ 29 2 PHAYGX96 Dissertation (60 credits) ......................................................................................... 30 Exit Awards .................................................................................................................................... 30 3 Welcome from the Programme Team Welcome to UCL School of Pharmacy and congratulations on gaining a place to study here on the MSc in Medicinal Natural Products and Phytochemistry (formerly MSc in Pharmacognosy). Pharmacognosy in the UCL School of Pharmacy has a prestigious and continuous tradition dating back to 1843, when Prof Pereira FRS started his teaching on Materia medica. He was followed by many more pharmacognosists who exerted a great influence in the discipline, including Prof Wallis, Prof Fairbairn, Prof Phillipson, and Prof Evans. Prof Heinrich, Prof Gibbons, Dr Prieto-Garcia, Dr Min Yang and Dr Stapleton form the core academic staff contributing to its design, coordination and delivery. This also benefits from the input of worldwide recognised experts including Prof Simmons (Director of Jodrell Laboratories at Kew Gardens) and Prof Houghton (Emeritus Prof at King’s College) among many others. The programme aims to deliver a modern, broad vision of herbal medicines and natural products with therapeutic uses by using a blended and dynamic learning approach. Our limited places ensure that our candidates enjoy continuous and close tuition. Full time, 4months research projects guarantee the acquisition of the necessary scientific skills to further your education in a PhD programme or to work in the industry. Completing an MSc in 12 months is a challenge, particularly for international students who are studying in a foreign language. Moving to a new country, leaving behind family and friends can be overwhelming. Good time management and practising and improving your English will help you cope with the demands of the programme, as will forming friendships with your fellow students. The relationships you build over the next year, especially those with the School itself, will last a lifetime and we are sure that you will always look back on your time with us with fond memories. Do read this handbook carefully and keep it for reference throughout the year. Your tutors at the School are here to mentor and to support you, so if you have any problems or queries do come and talk to one of us. We wish you good luck with your studies and look forward to getting to know you over the coming year. Dr Jose M. Prieto-Garcia Dr Min Yang Programme Director Deputy Programme Director 4 1. General Information PROGRAMME HANDBOOK This Programme Handbook provides an introduction to the programme and contains the key information you need about the programme of study. Amongst other things, this handbook covers the curriculum, teaching and learning, administrative procedures, key personnel and assessment. This handbook should be read in conjunction with the School Student Handbook which provides information about School staff, academic regulations and policies and administrative procedures. The Handbook is relevant to you throughout your studies. There will inevitably be some changes during your time with us, possibly in relation to the teaching staff, programme content and assessment patterns and we shall keep you informed of any important changes. However, you should make sure that you keep up to date by reading our communications, checking the notice boards, reading your emails and browsing Moodle and the School and UCL Websites. More detailed information on UCL procedures and policies in relation to students can be found on the UCL website at the following link: http://www.ucl.ac.uk/current-students. You can also find important on the School website here: www.ucl.ac.uk/pharmacy/currentstudents. Students are expected to be fully aware of procedures but, if in any doubt, please enquire at the Student and Academic Support Office (known as the School Office – SASO). We hope you find this handbook useful. It is revised every year to include new information and to make it easier to use. If you have any comments about the handbook or suggestions for improving the information provided, please forward your comments to the School Office (SASO) (email sop.saso@ucl.ac.uk). 5 1.2 PROGRAMME STAFF Programme Team Most academic members of the Pharmaceutical and Biological Chemistry staff contribute to the MSc in Pharmacognosy. Programme Director Dr Jose Prieto-Garcia Room: 201d Tel: 020 7753 5841 Email: j.prieto@ucl.ac.uk Deputy Programme Director Dr Min Yang Room: 439a Tel: 020 7753 5913 Email: m.yang@ucl.ac.uk Academic Staff Name Role Dr Jose M. Prieto-Garcia Programme Director, Lecturer in Pharmacognosy Prof Simon Gibbons Professor of Medicinal Phytochemistry and Head of Department, Deputy Programme Director Prof Michael Heinrich Head of Centre for Pharmacognosy & Phytotherapy Prof Peter Houghton Emeritus Professor of Pharmacognosy, King’s College London Dr Paul Stapleton RCUK Fellow Prof Monique Simmonds Head of Biological Interactions Group, Royal Botanic Gardens Kew Prof Klara Valko Senior Investigator, GlaxoSmithKline Dr Mike Munday Academic Director of Studies and Senior Lecturer Dr Werner Knöss Head of Department, Federal Institute for Drugs and Medical Devices, Germany 6 Name Role Dr Linda Anderson Principal Pharmacist, Medicines and Healthcare Regulatory Authority (MHRA) Dr Colin Wright Reader in Pharmacognosy, Bradford University Dr Min Yang Lecturer in Pharmaceutical & Biological Chemistry Dr Gary Parkinson Lecturer in Structural Chemistry Dr Rosemary Smyth Teaching and Research Assistant Dr. Denzil Philips CEO Denzil Philips International Dr Ivo Pischel Visiting Senior Lecturer Dr Rocio Alarcon Manager of the Lamoe centre, Ecuadorian Amazon. Dr Sarah Edwards Research Fellow Dr Geoff Wells Lecturer in Medicinal Chemistry Dr Rajindra Puri Senior Lecturer in Environmental Anthropology, Director of Learning and Teaching; Director of the CBCD, University of Kent 1.3 PROGRAMME ADMINISTRATION The School Office (SASO) is the main administrative hub for your programme of study and is located in Room G11, Brunswick Square. Opening Hours and Contact Information Hours: 09.00 to 17.00 (Monday-Friday) Location: Room G11, Brunswick Square Tel/Fax: +44 (0) 20 7753 5831 Fax: +44 (0) 20 7753 5829 E-mail: sop.pharmacy@ucl.ac.uk You may also need to visit the UCL Student Centre on some occasions and further information can be found here: http://www.ucl.ac.uk/current-students/student-centre 7 Postgraduate Programmes Manager Dr. Smyth provides general support on academic and welfare matters for students on the fulltime postgraduate programmes at the School (MSc and MRes). Dr Rosemary Smyth Room: 432 Tel: 020 7753 5950 Email: r.smyth@ucl.ac.uk END OF SECTION 1 8 2. Programme Information 2.1 PROGRAMME DETAILS Award: MSc Medicinal Natural Products and Phytochemistry Awarded by: University College London Department: Pharmaceutical and Biological Chemistry Length and Mode: 1 year full-time Credits: 180 credits at Level 7 ECTS: 72 ECTS Programme Director: Dr Jose M. Prieto-Garcia Deputy Programme Director: Dr Min Yang Teaching site UCL School of Pharmacy 29/39 Brunswick Square London WC1N 1AX UK Tel: 020 7753 5800 Fax: 020 7753 5829 9 2.2 THE MSC MEDICINAL NATURAL PRODUCTS AND PHYTOCHEMISTRY PROGRAMME The MSc in Medicinal Natural Products and Phytochemistry is a 12 month full-time taught postgraduate programme intended for those who wish to prepare for PhD-level research in natural product science or to pursue a career in the phytopharmaceutical industry or a government regulatory body. The programme is designed for students wishing to pursue a natural sciences oriented career in research and development in the herbal, phytopharmaceutical or (health) food sector as well as in drug discovery. Other opportunities exist in the context of regulatory requirements and the media/consumer support. 2.3 MASTER’S LEVEL DESCRIPTORS Master’s level awards are set at Level 7 of the Framework for Higher Education Qualifications in England, Wales and Northern Ireland (FHEQ) published by the Quality Assurance Agency for Higher Education (QAA). Descriptors for the Level 7 qualification are in two parts – (1) what each student must demonstrate in order to gain the award, and (2) the wider abilities that the typical student is expected to develop. The MSc degree is awarded to students who have demonstrated: 1. Systematic understanding of knowledge and skills required in the application of pharmaceutical care. 2. Critical awareness of current problems and/or new insights in pharmacy practice. 3. Comprehensive understanding of techniques applied to advanced scholarship in pharmaceutics, which include problem solving skills, evaluation, research methods and data analysis. 4. Originality in the application of knowledge, together with a practical understanding of how established techniques of research and enquiry are used to create and interpret knowledge in pharmaceutics. 5. Conceptual understanding that enables the student to: Evaluate critically current research and advanced scholarship in the discipline, and Evaluate methodologies and develop critiques of them and, where appropriate, to propose new hypotheses. 10 Typically, holders of the MSc degree will be able to: 1. Deal with complex issues both systemically and creatively, make sound judgments in the absence of complete data, and communicate their conclusions clearly to specialist and non-specialist audiences; 2. Demonstrate self-direction and originality in tackling and solving problems, and act autonomously in planning and implementing tasks at a professional or equivalent level; 3. Continue to advance their knowledge and understanding through continuing professional development, and 4. Develop new skills to an advanced level in pharmaceutics. and will have: 5. The qualities and transferable skills necessary for employment requiring: The exercise of initiative and personal responsibility; decision-making in complex and unpredictable situations, and 2.4 The independent learning ability required for continuing professional development. PROGRAMME STRUCTURE The MSc programme comprises two main components: (1) four full time taught modules (30 credits each) and (2) a full time, 4 months research project (60 credits worth). The taught modules are assessed by a combination of coursework and written examination. Students take two modules in the first term and a further two modules in the second term, followed by a substantial research project in the final term. The first term will cover in depth the basis for the medicinal use of natural products (Module 1 PHAYG019 Medicinal Natural Products) and the analytical methods for their quality control (Module 2: PHAYG024 Analytical Techniques in Phytochemistry). The second term will cover the Pharmacognosy discipline in further depth with lectures on how to interpret, design and apply analytical and bioassay methods for the bioguided isolation natural products (Module 3: PHAYG026 Natural Product Discovery) how to interpret, design and apply ethnopharmaceutical studies of plants and the philosophy behind their uses in traditional systems of medicines and their place in the developing global phytopharmaceutical industry Module 4: PHAYG035 Biodiversity and Medicines). The last term is dedicated full time to the research dissertation (PHAYGX96). 11 MSc in Medicinal Natural Products and Phytochemistry First term Second term (Oct-Dec) (Jan-Apr) Medicinal Natural Products Analytical Techniques in Phytochemistry PHAYG019 PHAYG024 30 credits 30 credits Natural Product Discovery Biodiversity and Medicines PHAYG026 PHAYG035 30 credits 30 credits 12 Third term (May-Aug) Research Project & Dissertation PHAYGX96 60 credits 2.5 LEARNING AND TEACHING METHODS Teaching is via Lectures (theoretical & practical), participation at workshops, seminars and forums, and visits to external companies. Self-directed learning is allocated as many hours as contact hours with the staff. It is supported by our (1) virtual learning system which provides with all teaching materials in electronic form (2) library services providing an extensive range of textbooks and access to electronic journals together with guidance on how to use scientific software. The course is assessed by marked assignments (essays, videos, and multimedia presentations), research projects, dissertations and past exam papers. You receive feedback on all your assessed work, with particular emphasis being given to the development of skills through the period of each module. Some lectures and seminars in the first term are shared with the MSc in Drug Discovery and fourth year students on the Master of Pharmacy degree. This is because the material is highly relevant and pertinent to the course. The teaching in the second term will be more specialised and there will be a heavy input by World recognised experts in Natural Products from the Royal Botanic Gardens at Kew, King’s College London and the Universities of Bradford and Reading. 2.6 CAREER RELEVANCE AND EMPLOYABILITY Completing this degree course will equip you with a set of key transferable skills which will be relevant for the workplace as well as providing you with a base of postgraduate level science knowledge and understanding. You will learn to critically evaluate current research and advanced scholarship within Pharmacognosy, as well as evaluating research methodologies. You will learn to deal with complex issues and make sound judgments and decisions in complex and unpredictable situations. You will learn to communicate information and conclusions to specialist scientific audiences, work effectively as part of a team, and demonstrate self-direction and originality in tackling and solving problems and act autonomously in planning and implementing tasks at a professional level. 13 The nature of this qualification will develop your independent learning skills, such as critical reading, as well as enhancing your ICT skills for both literature searching and managing information and strengthening your communication skills with others in both professional and academic contexts. Having this qualification coupled with practical experience could open up career opportunities in various scientific and medical research fields in the public and private sectors, for example, in the pharmaceutical companies, medical research, universities, commercial laboratories and independent healthcare providers. END OF SECTION 2 14 3. Modules 3.1 MODULE CHOICE All of the modules for the MSc in Medicinal Natural Products and Phytochemistry are compulsory so students are not required to choose modules. Term 1 – 2 core modules PHAYG019 Medicinal Natural Products 30 credits PHAYG024 Analytical Techniques in Phytochemistry 30 credits Term 2 – 2 core modules PHAYG026 Natural Product Discovery 30 credits PHAYG035 Biodiversity and Medicines 30 credits Term 2 & 3 – core research module: PHAYGX96 Dissertation - MSc Medicinal Natural Products and Phytochemistry 3.2 60 credits MODULE OUTLINES You will receive more detailed Module outlines at the start of the module and the content may be slightly different to the information published here. This is because staff are constantly updating their teaching in light of developments in current research and new thinking. 15 First Term PHAYG019 MEDICINAL NATURAL PRODUCTS Module Leader(s): Dr Jose Prieto-Garcia and Prof Michael Heinrich Learning Outcomes The student will gain a critical knowledge of the theoretical background and current application of the main Analytical Techniques used in Modern Phytochemistry for the study of crude drugs and extracts Topics 1. Traditional Herbal Medicinal Products (THMPs) a. Background of the European Directive b. Quality, Safety, Efficacy c. Current Role in the healthcare system 2. Homeopathic products a. Regulation b. Quality, Safety, Efficacy c. Current Role in the healthcare system 3. Food Supplements and Nutraceuticals a. Regulation b. Quality, Safety, Efficacy c. Their role in health 4. The use of medicinal natural products by different cultures a. An introduction to Ethnopharmacology b. Traditional Chinese Medicine c. Ayurveda d. Western Phytotherapy e. The role of CAM in modern healthcare systems 5. Clinical and Recreational Use of Natural Products a. Medicinal Natural Products from microorganisms b. Anticancer Natural Products from Plants c. Natural drugs of abuse and ‘legal highs’ 16 Teaching and Learning Strategy Lectures Theoretical Lectures will take place in a lecture theatre. Invited speakers of Worldwide recognised prestige such as Prof Monique Simmons (Kew Gardens), Prof Werner Knoess (European Medicines Agency) and Dr Linda Anderson (MHRA-British medicines agency) among others will join the teaching staff. Multimedia-Forum Discussion of some topics take place after watching carefully selected films and videos. Self Directed Learning A case study of the use of medicinal natural products by patients will be allocated to groups of students. You will present your results in public at the end of the module. 17 PHAYG024 ANALYTICAL TECHNIQUES IN PHYTOCHEMISTRY Module Leader(s): Dr Jose Garcia-Prieto Learning Outcomes The student will gain a critical knowledge of the theoretical background and current application of the main Analytical Techniques used in Modern Phytochemistry for the study of crude drugs and extracts, including: 1. Pharmacopoeial Methods a. Macroscopy b. Microscopy c. Ashes, Water content, Insoluble matter 2. Extraction procedures a. Liquid extraction from solid plant materials b. Liquid-Liquid extraction (partition) c. Steam distillation 3. Colorimetric Analysis a. Qualitative b. Quantitative 4. Thin Layer Chromatography (TLC) a. Classic TLC b. High Performance TLC 5. Instrumental Chromatography a. High Performance Liquid Chromatography b. Gas Chromatography 6. Mass Spectrometry a. Small molecules b. Macromolecules 7. Electrophoresis 8. X-Ray diffraction 9. Nuclear Magnetic Resonance 10. Descriptive Phytochemistry a. Phenolic substances b. Alkaloids c. Terpenes d. Microbial secondary metabolites 18 Teaching and Learning Strategy Lectures Theoretical Lectures will take place in a big lecture theater together with MSc Drug Discovery students (MADD module). Practical lectures About 50% of this module takes place in our new brand teaching laboratories. You will receive a Laboratory notebook where to record your experiments. Workshops They will take place usually in small seminar rooms and are attended only by MSc in MNP&P students Self Directed Learning A number of student-lead seminars will cover Descriptive Phytochemistry, namely the description and structure of the main Natural Products classes. 19 Second Term PHAYG026 NATURAL PRODUCT DISCOVERY Module Leader(s): Dr Jose Garcia-Prieto and Dr Paul Stapleton Learning Outcomes The student will gain a critical knowledge of the theoretical background and current application of the main Chemical and Biological Techniques used to discover new drugs from natural products. Topics 1. Methods in Natural Product Drug Discovery a. Extraction, separation methods (isolation) and structure elucidation b. Chemical diversity and its importance c. Industrial approach to natural drug discovery d. Assay (target) selection, project teams, dereplication e. Natural product libraries and other approaches f. Case studies – examples of drugs from natural sources 2. Elucidation of Natural Products a. Mono- and bi-dimensional NMR techniques 3. Semi synthesis of natural products 4. Fundamentals on the design of biological assays a. The Scientific method b. Design of Experimental Protocols c. Basic statistical concepts d. In vitro vs. In vivo assays 5. Major drivers for natural products research a. Antioxidants i. Generalities: radical scavenging and lipoperoxidation ii. Practical: the DPPH assay b. Cytotoxicity i. Generalities: Apoptosis and necrosis ii. Practical: Cell culture techniques c. Neurodegeneration i. Generalities: Alzheimer and Parkinson disease ii. Practical: Acetylcholinesterase inhibitors d. Antibiotics i. Generalities: antimicrobials ii. Practical: MICs 20 Teaching and Learning Strategy Lectures Theoretical Lectures will take place in a small lecture theatre together with MRes students. Practical lectures They will give you hands on experience in a range of bioassays and takes place in our new brand teaching laboratories. You will receive a Laboratory notebook where to record your experiments. Workshops They will take place usually in small seminar rooms and are attended only by MSc in MNP&P and MRes students Self directed learning A number of scientific papers seminars covering aspects of this module will be critically reviewed. 21 PHAYG035 BIODIVERSITY AND MEDICINES Module Leader(s): Dr Jose Garcia-Prieto and Prof Michael Heinrich Learning Outcomes The student will gain a critical knowledge of the theoretical background and current application of the main Chemical and Biological Techniques used to discover new drugs from natural products. Topics 1. Biodiversity, Conservation and Ethnopharmacology: The Fundamental Challenges 2. a. Generalities some theoretical considerations b. Drugs from Natural sources – Extracts as ‘actives’ c. Travelling people – migration and the changing needs in ethnopharmacology d. Value chains – new research needs in medicinal plant research e. Risk of herbal medicines in a changing environment f. How to communicate in ethnopharmacology: writing a scientific paper Qualitative and quantitative methods in Ethnopharmacology 3. New Medicines-based Traditional Knowledge: Indigenous and Intelectual Property Rights from an Ethnopharmacological perspective a. Generalities b. The Convention on Biodiversity (CBD) 4. Ethnobiology a. Generalities b. Visits and activities in Allotments and Gardens 5. Exploitation and Protection of the Biodiversity a. The CBD b. Regulation of borderline medicinal products 6. Botanical Gardens: repositories of the biodiversity 7. A walk through the Rainforest a. Tropical Plants as a source of medicines: The case Curare and Atracurium b. Conservation and ethnobotany in the Amazon: The case of Yasuni Park c. Tropical Fungi as a source of medicines: Visit to Hypha Discovery 22 Teaching and Learning Strategy Super Learning days Each topic is developed in Thematic days including two-super learning days with students at the University of Kent, one super learning day at Kew Gardens, one super learning day on the rainforest at the school of pharmacy. Self-directed learning An ethnopharmacological paper will be critically reviewed. A monograph for a medicinal plant will be written. Visits Urban ethnobiology (Allotments in Canterbury) Monographies in The Mecklenburg garden Visit plus lecture in the Chelsea Physic garden Visit plus lecture in the Royal Botanical gardens at Kew Visit plus lecture at Hypha Discovery, a natural products drug discovery company. END OF SECTION 3 23 4. Research Project 4.1 OVERVIEW PHAYGX96 Dissertation – MSc Medicinal Natural Products and Phytochemistry Module Leader(s): Dr Jose Garcia-Prieto and Prof Simon Gibbons A major component of the MSc in Medicinal Natural Products and Phytochemistry course is the research project. Projects will be assigned in December and will be supervised by an academic member of staff from the School who has a research interest in natural product science. This will cover a number of diverse topics ranging from isolation of bioactive products, natural product synthesis, analysis of natural products and herbal medicinal product use in the community. The projects will be undertaken in the laboratory of a member of staff between May and August inclusive. Students are expected to develop their own research ideas and experimental series in discussion with their supervisor and complete a comprehensive literature review to supplement their work. Results will be written up and submitted as a dissertation and presented in an oral presentation at the end of the year in the first week of September. END OF SECTION 4 24 5. Assessment and Regulations 5.1 PROGRAMME REGULATIONS The full Programme Regulations for Taught Postgraduate Programmes can be found on the UCL website at the link below. Students must also read the information contained in the School Student Handbook. We have included a brief summary of the main regulations in this handbook; however students must read the regulations in full. http://www.ucl.ac.uk/ras/acd_regs Coursework Students must complete a number of formative and summative assignments. Formative assignments give feedback to students on their performance but do not count towards final marks (however, it may still be a requirement to complete these). Marks for summative assignments do count towards the final mark for each module. The minimum pass mark is 50%. Examinations Students will normally take written examinations for term 1 modules in January and written examinations for term 2 modules in April-June. Resit examinations are normally held in the last week of August or the first week of September and will be of the same format and duration as term 1 and 2 examinations. The minimum pass mark for examinations is 50%. Overall module marks Your overall mark for each module will be made up of your coursework and exam marks. Most modules are assessed by 33% coursework and 67% examination. Aggregation To pass a module you must obtain overall at least 50%, including a coursework mark of 50% at minimum. If you achieve between 40% and 50% in your exam and your overall module mark calculates at over 50% then you are permitted to pass the module. Resits The regulations permit students a first opportunity at an assessment and one resit opportunity only (at the discretion of the Board of Examiners). No further opportunities are permitted. The higher of the marks achieved at the first attempt and the re-sit attempt will apply. Students cannot resit modules which they have passed. 25 Condoning Please refer to the Post Graduate Taught Academic Regulations, Section 3 (3.2.4) https://www.ucl.ac.uk/srs/academic-regulations Final Degree Mark The overall pass mark for the award of the MSc is 50%. The final degree mark is calculated on the average module marks weighted according to the number of credits they carry. The Master’s degree is worth 180 credits in total so a 30 credit module would contribute 30/180 to the final mark. Criteria for the Award of Pass, Merit and Distinction Please refer to the Post Graduate Taught Academic Regulations, Section 2 (2.10.6) https://www.ucl.ac.uk/srs/academic-regulations 5.2 ASSESSMENT First term PHAYG019 MEDICINAL NATURAL PRODUCTS Formative assessment A series of MCQs will challenge your understanding of the lectures received. This will not contribute to the final mark of the module but you need to pass with 80%. Student presentations of a Case-Study Your performance and self-directed study related with descriptive phytochemistry will be assessed by means of your presentation of a class of secondary metabolites. Student presentations of a poster Your performance and self-directed study related with the potential and limitations of promising medicinal natural products will be assessed by means of your presentation of a topic of your choice in the form of poster. Unseen Paper Your performance in an unseen paper covering ALL materials imparted in the lectures during the module. 26 PHAYG024 ANALYTICAL TECHNIQUES IN PHYTOCHEMISTRY Formative assessment A series of MCQs will help you understanding of the practicals and lectures received. You can take the MCQs as many times as you need until scoring over 80%. This will not contribute to the final mark of the module though. Laboratory Notebook Your performance and self-directed study related with practical lectures will be assessed by means of your laboratory notebook. Student-Lead Seminars Your performance and self-directed study related with descriptive phytochemistry will be assessed by means of your presentation of a class of secondary metabolites Unseen Paper Your performance in an unseen paper covering ALL materials imparted or self-studied during the module. PHAYG026 NATURAL PRODUCT DISCOVERY Formative assessment A series of workshops will guide you on how to apply different analytical techniques to the isolation and structural elucidation of small natural drugs. Laboratory Notebook Your performance and self-directed study related with practical lectures will be assessed by means of your laboratory notebook. Coursework Your performance at the critical review of carefully selected scientific papers will be assessed. Unseen Paper Your performance in an unseen paper covering ALL materials imparted or self-studied during the module. PHAYG035 BIODIVERSITY AND MEDICINES Formative assessment A series of workshops and outdoor activities will guide you on how to apply different ethnobotanical methods. 27 Coursework Your performance at the critical review of a scientific papers and the writing of a monograph will be assessed. Unseen Paper Your performance in an unseen paper covering ALL materials imparted or self-studied during the module. 28 5.3 SCHEME OF AWARD The Scheme of Award sets out the individual assessment components and their relative weighting. Students will be subject to the scheme of award in effect at the time they start the programme. The MSc is worth 180 credits. It is comprised of 120 credits of taught modules and a 60 credit dissertation. The MSc in Medicinal Natural Products and Phytochemistry comprises the following weighted assessment components: PHAYG019 Medicinal Natural Products (30 credits) Assessment Component Weighting Coursework 33% Unseen 3 hour written examination 67% PHAYG024 Analytical Techniques in Phytochemistry (30 credits) Assessment Component Weighting Coursework 33% Unseen 3 hour written examination 67% PHAYG026 Natural Product Discovery (30 credits) Assessment Component Weighting Coursework 33% Unseen 2 hour written examination 67% PHAYG035 Biodiversity and Medicines (30 credits) Assessment Component Weighting Coursework 33% Unseen 2 hour written examination 67% 29 PHAYGX96 Dissertation (60 credits) Assessment Component Weighting Presentation 10% Dissertation 90% Exit Awards Credits Award name: MSc 180 MSc in Medicinal Natural Products and Phytochemistry Postgraduate Diploma 120 PG Dip Medicinal Natural Products and Phytochemistry Postgraduate Certificate 60 PG Cert Medicinal Natural Products and Phytochemistry END OF SECTION 5 30 Appendix 1: Calendar The MSc is a full-time, twelve-month programme. Students should not plan any activities to interfere with the 9:00am – 5:00pm schedule, Monday – Friday for the entirety of the programme. Event Date Induction Week 28 September 2015 Term 1 Starts 28 September 2015 Classes start 05/10/2015 Term Ends 18 December 2015 Term 2 Starts 11 January 2016 Examination Period 11 – 15 January 2016 Term 2 Ends 24 March 2016 Term 3 Starts 25 April 2016 Examination Period April - June 2016 Research Project Starts The day after your last exam paper Term 3 Ends 31 August 2016 Deadline for Project Submission 2 September 2016 Resit Examination Period Late August/Early September 2016 Important Notes 1. UCL School of Pharmacy reserves the right to change these dates if necessary. The School will inform students of any changes. 2. Students must ensure that they are available to attend all classes throughout the terms. 3. Students on full-time Taught Master’s programmes study for a full calendar year. Therefore students are expected to study beyond the end of the third term to prepare their dissertation in time for submission in September. 31