Product datasheet
Anti-UGT2B4 antibody - N-terminal ab156229
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Overview
Product name
Anti-UGT2B4 antibody - N-terminal
Description
Rabbit polyclonal to UGT2B4 - N-terminal
Tested applications
WB
Species reactivity
Reacts with: Human
Immunogen
Synthetic peptide conjugated to KLH, corresponding to region within N terminal amino acids 6896 of Human UGT2B4 (UniProt ID: P06133).
Positive control
MDA-MB453 cell line lysates.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 99% PBS
Purity
Immunogen affinity purified
Purification notes
ab156229 is purified through a protein A column, followed by peptide affinity purification.
Clonality
Polyclonal
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab156229 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
WB
Abreviews
Notes
1/100 - 1/500. Predicted molecular weight: 61 kDa.
Target
Relevance
The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and
enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by
transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups.
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They have been subdivided into two families, UGT1 and UGT2, based on the evolutionary
divergence of their genes. The enzymes of the UGT1A family play an important role in the
metabolism of dietary constituents, phenols, and therapeutic drugs, and also the glucuronidation
of bilirubin and iodothyronines. The enzymes of the UGT2B family are involved in the metabolism
of bile acids, phenol derivatives, catecholestrogens and steroids. Although it is widely
recognized that the liver is the major site of glucuronidation, it is now clear that UGT enzymes are
also found in extra-hepatic tissues.
Cellular localization
Microsome
Anti-UGT2B4 antibody - N-terminal images
Anti-UGT2B4 antibody - N-terminal
(ab156229) at 1/100 dilution + MDA-MB453
cell line lysates at 35 µg
Predicted band size : 61 kDa
Western blot - Anti-UGT2B4 antibody - N-terminal
(ab156229)
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