Supplementary Information for
Single-cell enabled comparative genomics of a deep ocean SAR11 bathytype
J. Cameron Thrash1,2,*, Ben Temperton1, Brandon K. Swan3, Zachary C. Landry1, Tanja
Woyke4, Edward F. DeLong5, Ramunas Stepanauskas3 and Stephan J. Giovannoni1
1. Department of Microbiology, Oregon State University, Corvallis, OR 97331
2. Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, 70803
3. Bigelow Laboratory for Ocean Sciences, East Boothbay, ME 04544
4. DOE Joint Genome Institute, Walnut Creek, CA 94598
5. Departments of Civil & Environmental Engineering and Biological Engineering,
Massachusetts Institute of Technology, Cambridge, MA 02139
*To whom correspondence should be addressed: thrashc@lsu.edu
Supplementary information contains:
Supplementary Text
Supplementary Methods
Supplementary Figures S1-15
Supplementary Table_S1_F.xlsx
Additional supporting text files, including scripts, supporting text files and fasta files, and SAG
genome data, are available on the Giovannoni Lab website at:
http://giovannonilab.science.oregonstate.edu/publications
Page 1 of 21
Supplementary Text
Basic comparative genomics results
Table S1 details the results of our comparative genomics analysis using categorization of the
1764 orthologous clusters (OCs) found in the SAGs according to other SAR11 membership:
those unique to a given SAG (unique), those shared by 2-4 SAGs but not by any other SAR11
genomes (shared Ic), those shared by all isolates and 1-3 SAGs (possible core), and those
shared in all SAGs and all isolates (true core). All other distributions were not categorized. Each
gene categorization and OC membership is cataloged in Table S1 and displayed in order along
each scaffold in Figure S15. The incomplete nature of the SAGs makes it impossible to rule out
the presence of an ortholog in the source cell and given the high percentage of conserved core
genes among distantly related pure culture strains (Grote et al., 2012), possible core orthologs
were so termed because their presence in all isolate genomes and at least one SAG made
these the most likely candidates for missing orthologs in the remaining SAGs. There were 172
true core (10%) and 480 possible core (27%) OCs. The 544 SAG-specific clusters contained
400 unique (23%) and 144 shared Ic (8%) clusters, and 568 OCs (32%) had some other shared
distribution among SAGs and pure-culture genomes.
Negative data with regards to previously reported deep-ocean characteristics
Many characteristics previously associated with deep ocean microorganisms, whether obtained
from cultivated strains (Lauro and Bartlett, 2008, Nagata et al., 2010, Simonato et al., 2006)(and
references therein) or from cultivation-independent analyses (Konstantinidis et al., 2009), were
either not observed in the subclade Ic genomes, or were present, but shared with surface
genomes. We examined amino acid substitution patterns among orthologs shared between the
SAGs and the surface genomes (Konstantinidis et al., 2009) (Figs. 6, S10). While the overall
magnitude of the substitution differences was small, the general trend was for relative increases
in cysteine, isoleucine, lysine, asparagine, arginine and tryptophan in the predicted subclade Ic
protein sequences at the expense of alanine, aspartatic acid, glutamic acid, methionine,
glutamine, threonine and valine. These trends mostly held true when comparing amino acid
substitutions with biochemically similar or different residues (+ and - results in blast output,
respectively). The exceptions were in the cases of cysteine and asparagine, which showed
relative increases only when examining different and similar amino acid substitutions,
respectively (Fig. S12). Increased arginine and tryptophan residues were reported in a 4000 m
sample from station ALOHA (Konstantinidis et al., 2009), yet many of the other depthassociated trends observed in that whole-community metagenome study were opposite our
Page 2 of 21
more targeted SAR11 taxon analysis, for example, histidine and alanine were more frequently
substituted in the surface strains compared to the SAGs, and the reverse was true for isoleucine
and lysine.
We identified no unique genes for polyunsaturated fatty acid synthesis, no unique
duplications in ATPases or cytochrome c oxidases, and no unique genes for complex polymer
utilization, such as pullulan, chitin, or cellulose. AAA240-E13 had a unique predicted
xylanase/chitin deacetylase, however an OC with the same annotation was found in the isolate
genomes (Table S1). In spite of their isolation from the ALOHA OMZ and considerable
recruitment of metagenomic sequences from the heart of the ETSP OMZ at 200 m, the SAGs
did not encode a high affinity cbb3-type cytochrome c oxidase, nor any genes for alternative
terminal electron accepting processes, such as nitrate reductases. The SAG 16S rRNA genes
didn’t have insertions associated with some piezophilic strains (Lauro et al., 2007) (Fig. S16).
There were no unique tonB-type transporters, or ompH/L genes, and none of the SAGs had
genes for the Strickland reaction other than thioredoxin, thioredoxin reductase, and a translation
elongation factor (these three genes were not unique to the SAGs). The SAGs had putative cold
shock protein genes and copies of the groE/L genes, but these were not unique to the Ic clade.
AAA240-E13 and AAA288-E13 had a unique pulJ type II secretion component, but many of the
surface strains had pillin and type II secretion genes. AAA288-N07 contained an intact aerobic
carbon monoxide dehydrogenase (CODH) gene cluster, but this was shared with HIMB5 and
HIMB114. Unlike the SAR324 and Arctic96-BD19 SAGs reported by (Swan et al., 2011), none
of the SAR11 SAGs contained unique autotrophy pathways. Finally, unlike the results of
(Konstantinidis et al., 2009), the SAGs showed no significant increases transposable elements
compared to the surface SAR11s (Table S1).
Additional observations based on relative abundance of genes in metagenomic datasets
Qualitative assessment of additional clusters showed several additional genes of interest that,
although were not statistically more abundant in deep samples compared to surface samples,
nevertheless had considerable recruitment at depth compared to surface samples (Table S1).
Among the additional genes highly abundant at depth that were also conserved among SAR11
genomes outside of the Ic subclade were predicted ABC-type amino acid transporters, TRAP
transporters, glutamate and glutamine synthases, FeS cluster assembly genes, sec and twin
arginine protein translocases, the coxL CODH subunit, subunits of the hetertetrameric sarcosine
oxidase (Yilmaz et al., 2011), thioredoxin reductase, and ferrodoxin (Table S1). The unique
xylanase/chitin deacetylase in AAA240-E13 (2236673789) was more abundant in deep water
Page 3 of 21
samples, however, the copy of this gene shared with other SAGs and the isolate genomes
(2236673495) was also among the most abundant genes in surface samples (Table S1).
Ribosomal
proteins
and
respiratory
proteins
such
as
cytochromes,
NADPH:quinone
oxidoreductase, and F0F1-type ATP synthases were also highly abundant in deep samples,
usually with much lower abundance in surface samples, indicating that these highly conserved
SAR11 genes probably have enough nucleotide divergence to serve as clade-specific markers.
There were also a number of highly conserved (possible or true core) hypothetical genes that
showed high abundance with depth.
Additional phage information
The SAGs shared genes with other SAR11 genomes that had at least partial homology to
Pelagiphage genes. Whole genome BLAST of the four recently sequenced Pelagiphage
genomes (Zhao et al., 2013) against the SAGs indicated significant hits > 100bp from two of
the Pelagiphage, HTVC008M and HTVC019P, to true core and possible core genes such as
NAD synthetase, peroxiredoxin, and ribonuclotide reductase, as well as flexible genome genes
such as that encoding a small heat shock protein, ribosomal protein S21, and hypothetical
proteins (Table S1).
Supplementary methods
Single-cell separation/ MDA
Water samples for single cell analyses were collected from the mesopelagic (770m) using
Niskin bottles during Hawaii Ocean Time-series (HOT) Cruise 215, station ALOHA (22°45ʹ′N,
158°00ʹ′W; 9 September 2009). Replicate, 1 mL aliquots of water were cryopreserved with 6%
glycine betaine (Sigma) and stored at −80ºC (Cleland et al., 2004).
Prior to cell sorting, samples with prokaryote cell abundances above 5x105 mL-1 were diluted
10x with filter-sterilized field samples and pre-screened through a 70 µm mesh-size cell strainer
(BD). For heterotrophic prokaryote detection, diluted subsamples (1-3 mL) were incubated for
10-120 min with SYTO-9 DNA stain (5 µM; Invitrogen). Cell sorting was performed with a
MoFlo™ (Beckman Coulter) flow cytometer using a 488 nm argon laser for excitation, a 70 µm
nozzle orifice and a CyClone™ robotic arm for droplet deposition into microplates. The
cytometer was triggered on side scatter. The “purify 1 drop” mode was used for maximal sort
purity. Prokaryote cells were separated from eukaryotes, viruses, and detritus based on SYTO-9
fluorescence (proxy to nucleic acid content) and light side scatter (proxy to particle size)(del
Giorgio et al., 1996). Synechococcus cells were excluded, based on their autofluorescence
Page 4 of 21
signal. Target cells were deposited into 384-well plates containing 600 nL per well of 1x TE and
stored at −80ºC until further processing. Of the 384 wells, 315 were dedicated for single cells,
66 were used as negative controls (no droplet deposited) and 3 received 10 cells each (positive
controls).
Cells were lysed and their DNA was denatured using cold KOH (Raghunathan et al., 2005).
Genomic DNA from the lysed cells was amplified using multiple displacement amplification
(MDA) (Dean et al., 2002, Raghunathan et al., 2005) in 10 µL final volume. The MDA reactions
contained 2 U/µL Repliphi polymerase (Epicentre), 1x reaction buffer (Epicentre), 0.4 mM each
dNTP (Epicentre), 2 mM DTT (Epicentre), 50 mM phosphorylated random hexamers (IDT) and
1 µM SYTO-9 (Invitrogen) (all final concentration). The MDA reactions were run at 30°C for 1216 h, then inactivated by a 15 min incubation at 65°C. Amplified genomic DNA was stored at 80°C until further processing. We refer to the MDA products originating from individual cells as
single amplified genomes (SAGs).
Prior to cell sorting, the instrument and the workspace were decontaminated for DNA as
previously described (Stepanauskas and Sieracki, 2007). High molecular weight DNA
contaminants were removed from all MDA reagents by a UV treatment in Stratalinker
(Stratagene). An empirical optimization of the UV exposure was performed to remove all
detectable contaminants without inactivating the reaction. Cell sorting and MDA setup were
performed in a HEPA-filtered environment. As a quality control, the kinetics of all MDA reactions
was monitored by measuring the SYTO-9 fluorescence using FLUOstar Omega (BMG). The
critical point (Cp) was determined for each MDA reaction as the time required to produce half of
the maximal fluorescence. The Cp is inversely correlated to the amount of DNA template
(Zhang et al., 2006). The Cp values were significantly lower in 1-cell wells compared to 0-cell
wells in all microplates for which MDA kinetics was monitored (p<0.001; Wilcoxon Two Sample
Test).
MDA products were diluted 50-fold in TE buffer and 500 nL aliquots of diluted MDA product
served as the template DNA in 5 µL final volume real-time PCR screens. All PCR reactions
were performed using LightCycler 480 SYBR Green I Master Mix (Roche) and the Roche
LightCycler® 480 II real-time thermal cycler. PCR amplification of SSU rRNA and metabolic
genes from SAGs was done using primers and conditions listed in Table S1. Forward
(5´−GTAAAACGACGGCCAGT−3´) and
reverse
(5´−CAGGAAACAGCTATGACC−3´) M13
sequencing primers were added to the 5´ ends of each target primer pair to aid direct
sequencing of PCR products. All PCR reactions were run for 40 cycles at the appropriate
annealing temperature, followed by melting curve analysis performed as follows: 95°C for 5 s,
Page 5 of 21
52°C for 1 min, and a continuous temperature ramp (0.11°C/s) from 52 to 97°C. Real-time PCR
kinetics and amplicon melting curves served as proxies for detecting SAGs positive for target
genes. New, 20 µL PCR reactions were set up for all PCR-positive SAGs and amplicons were
sequenced from both ends using Sanger technology by Beckman Coulter Genomics.
Single cell sorting, whole genome amplification, real-time PCR screens and PCR product
sequence
analyses
were
performed
at
the
Bigelow
Single
Cell
Genomics
Center
(www.bigelow.org/scgc).
Selection based on MDA reaction kinetics
Four SAGs in the Ic subclade were picked to cover the total depth of branching observed in the
16S phylogeny, and selected based on MDA reaction kinetics to improve the possibility of more
complete genome recovery. The kinetics of all MDA reactions was monitored by measuring the
SYTO-9 fluorescence using a FLUOstar Omega (BMG) plate reader. The MDA critical point
(Cp) was determined for each reaction as the time required to produce half of the maximal
fluorescence. The Cp value is inversely correlated to the amount of DNA template (Zhang et al.,
2006).
Sequencing/Assembly/Annotation
Draft genomes were generated at the DOE Joint genome Institute (JGI) using the Illumina
technology (Béjà et al., 2002). Illumina standard shotgun libraries were constructed and
sequenced using the Illumina HiSeq 2000 platform. All general aspects of library construction
and sequencing performed at the JGI can be found at http://www.jgi.doe.gov. All raw Illumina
sequence data was passed through DUK, a filtering program developed at JGI, which removes
known Illumina sequencing and library preparation artifacts (unpublished). The following steps
were then performed for assembly: 1) filtered Illumina reads were assembled using Velvet v.
1.1.04 (Stein et al., 1996), 2) 1–3 kbp simulated paired end reads were created from Velvet
contigs using wgsim (http://github.com/lh3/wgsim), 3) Illumina reads were assembled with
simulated read pairs using Allpaths–LG v. r41043 (Hsiao et al., 2005). Parameters for assembly
steps were: 1) Velvet: 63 -shortPaired and velvetg: -very clean yes -export -Filtered yes -min
contig lgth 500 -scaffolding no -cov cutoff 10, 2) wgsim: -e 0 -1 100 -2 100 -r 0 -R 0 -X 0, 3)
Allpaths: -LG PrepareAllpathsInputs: PHRED 64=1 PLOIDY=1 FRAG COVERAGE=125 JUMP
COVERAGE=25 LONG JUMP COV=50, RunAllpathsLG: THREADS=8 RUN=std shredpairs
TARGETS=standard VAPI WARN ONLY=True OVERWRITE=True.
Page 6 of 21
Each raw sequence data set was screened against all finished bacterial and archaeal
genome sequences (downloaded from NCBI) and the human genome to identify potential
contamination in the sample. Reads were mapped against reference genomes with bwa version
0.5.9 (Philippot, 2002) using default parameters (96% identity threshold). None of the libraries
showed significant contamination. Additionally, gene sequences of the final assemblies were
compared against the GenBank nr database by BLASTX and taxonomically classified using
MEGAN (Beaumont et al., 2002). Genes were identified using Prodigal (Hyatt et al., 2010). The
predicted CDSs were translated and used to search the National Center for Biotechnology
Information (NCBI) nonredundant database (nr), UniProt, TIGRFam, Pfam, KEGG, COG, and
InterPro databases. The tRNAScan-SE tool (Hacker and Kaper, 2000) was used to find tRNA
genes, whereas ribosomal RNA genes were found by searches against models of the ribosomal
RNA genes built from SILVA (Pruesse et al., 2007). Other non–coding RNAs such as the RNA
components of the protein secretion complex and the RNase P were identified by searching
genomes for the corresponding Rfam profiles using INFERNAL (Makarova et al., 1999).
Additional gene prediction analysis and manual functional annotation was performed within the
Integrated Microbial Genomes (IMG) (Markowitz et al., 2008) platform developed by the Joint
Genome Institute, Walnut Creek, CA, USA (http://img.jgi.doe.gov).
Orthology with other SAR11s
SAG orthologs were determined using the automated phylogenomics pipeline Hal (Robbertse et
al., 2011) combined with several curation steps. Protein-coding fastas for 8 pure-culture SAR11
genomes were obtained from IMG (https://img.jgi.doe.gov). Initial orthologous clusters were
established by all vs. all BLASTP and subsequent Markov clustering (MCL) at the inflation
parameter (I) 1.5, consistently with our previous work (Grote et al., 2012). These clusters were
then filtered for genes with ≥ 30% difference to the median gene length of the cluster, similarly
to (Grote et al., 2012), using cluster_size_filter.pl iteratively until clusters no longer split.
Because of the fragmentary nature of the SAGs, genes from these genomes were not subjected
to the same size filter, as it has been shown that highly incomplete genomes contain large
numbers of partial open reading frames (ORFs) (Klassen and Currie, 2012). A separate
evaluation of orthologs, based on synteny, was conducted using the methods of (Yelton et al.,
2011). Syntenic genes from all pairwise comparisons were coalesced into clusters using
synteny_clustering.py, and these clusters were compared with those from the Hal pipeline using
cluster_comparison.py. In cases where the syntenic clusters contained additional genes to
those in the Hal clusters, the cluster assignment based on synteny was used. Hypothetical
Page 7 of 21
proteins associated with extraneous, unused scaffolds from HTCC1002 (scaffolds 3-5) (Grote et
al., 2012) were manually removed. Finally, orthologous clusters for single-copy housekeeping
genes were manually inspected to ensure no erroneous mis-assignment during these
automated steps. As part of the Hal pipeline, cluster data is output in the form of a heatmap.
This heatmap was manually curated to reflect the changes to the original clustering based on
our filters. This heat map can be queried to establish numbers of shared orthologs between
different genomes. Table S1 and Figure S15 display five gene categories: 1) orthologs unique to
an individual SAG (unique), 2) orthologs shared among SAGs but not other SAR11 strains
(shared Ic), 3) orthologs shared among all pure culture SAR11 genomes and between one and
three SAGs (potential core), 4) orthologs shared among all SAR11 pure culture genomes and all
SAGs (true core), 5) everything else. Note that many clusters contain more than one gene from
a given genome. These may be considered paralogs for the purposes of this analysis, the same
as in (Grote et al., 2012), and paralogs were ignored for the purposes of counting shared
orthologs across clusters. However, caution should be used in interpreting duplicate genes
within clusters for two reasons: 1) due to the incomplete nature of the SAGs and the potential
abundance of partial or split ORFs across multiple scaffolds, duplicate genes from SAGs in a
given cluster may not reflect “real” duplicates, and 2) given the clustering is the result of a
partially automated pipeline and not hand-curated for each genome, the possibility remains that
clusters may be artificially concatenated due to the inflation parameter selected for Markov
Clustering.
Post-assembly SAG scaffold QC
Amplification of genomes from single cells increases the risk of contaminant DNA being
included in the downstream genome sequencing and subsequent assembly compared to
traditional sequencing of microbial genomes using billions-trillions of chromosomal copies.
Although pre- and post-amplification QC has very high success with decreasing such
contamination, sequenced SAG scaffolds were evaluated for possible cases of contamination
using BLASTN, tetramer analysis, and manual inspection all scaffolds smaller than 1000bp for
regions of low predicted ORF density. BLASTN of each scaffold was performed against the nr
database with default settings. Scaffolds were flagged for further evaluation if they contained
BLASTN hits with > 500bp alignment length to non-alphaproteobacteria, or if all BLASTN hits
were to non-alphaproteobacteria. Tetramer analysis of each scaffold was carried out using a
sliding window of 2000bp and a 200bp step. Principal Components Analysis (PCA) was carried
out on the results to identify outlying scaffolds/regions of scaffolds, and these were flagged for
Page 8 of 21
further evaluation. Those scaffolds flagged from the BLASTN and tetramer analyses were
manually inspected for gene conservation among the other SAR11 strains. Those containing
genes conserved in other strains were ruled out as contaminants. Finally all scaffolds smaller
than 1000bp were manually inspected for predicted ORF density. The streamlined nature of
SAR11 genomes results in very small non-coding regions throughout the genome, so scaffolds
were visually screened based on coding density. All flagged scaffolds resulting from these
analyses are identified in Table S1. However, it should be noted that a scaffold with BLASTN
hits to non-alphaproteobacteria or outlying tetramer scores is not sufficient to identify
contamination as these may simply reflect hypervariable regions within the SAG and/or
instances of horizontal gene transfer. Therefore, scaffolds flagged as possible contaminants are
to be treated with caution.
Circos plot
Circos plots were generated using Circos version 0.62-1. Scaffolds for each SAG were placed in
order of size from largest to smallest. IMG annotations and OC designations were used as the
base categorizations for the plot. GC content for each gene is represented as displayed in IMG.
Links files were produced using a custom python script to organize segment duplications by OC
designations using previously created tab-delimited files. The python script, Circos configuration
files, and input data are available upon request.
Estimated genome completion
SAG genome completion was evaluated based on 599 single-copy genes present in all eight
pure-culture SAR11 genomes. Overall SAG genome completion percentage was based on the
percentage of these genes found in the SAGs (Table S1).
AAI vs. 16S identity
Average amino acid identity was calculated with the scripts/methods of (Yelton et al., 2011).
Pairwise 16S rRNA gene identity was calculated with megablast using default settings. All data
is available in Table S1. The heatplot of AAI vs. 16S was made in R.
COG distribution
The barplot (Fig. 4) and boxplot (Fig. S9) of the COG distribution among SAR11 genomes was
built using data supplied by IMG (Table S1) with R.
Page 9 of 21
Amino acid distribution
Amino acid substitution pattern analysis was performed as described in Konstantinidis et al.
2009 (Konstantinidis et al., 2009). Briefly, the fasta file for each HAL cluster was used as a
BLASTP query against a database containing non-redundant proteins from 8 surface SAR11
strains and 4 SAGs from 770m at ALOHA. Alignments with an expect value of less than 1 x 1020
were discarded. For remaining alignments, the number of similar amino acid substitutions,
different amino acid substitutions and gaps was calculated between all surface strain proteins
and SAG proteins. The fold-change in abundance of each amino acid between surface strain
proteins and SAG proteins was calculated. All analyses are available in the IPython notebook
‘Calculating amino acid changes.ipynb’.
Intergenic spacer analysis
Intergenic spacer regions are provided as part of the IMG annotation process. Sizes and
statistics for each set of intergenic regions were calculated using the fasta_length_counter.pl
script. Distribution of intergenic regions was examined in R with histograms and box plots, and
R was also used to run the Wilcoxon rank sum analysis:
> wilcox.test(hist$surface,histr$Ic,paired=FALSE,conf.int=TRUE,conf.level=0.95)
All analyses only included non-zero intergenic regions calculated by IMG.
Transposable elements
Transposable elements were assessed using the sequences collected by Brian Haas of the
Broad
Institute
for
the
program
TransposonPSI
(http://transposonpsi.sourceforge.net).
Sequences from this library (1537) were searched against a database of SAR11 genomes (see
metagenomic reciprocal best blast, below) using tblastn on default settings.
Deep water adaptation genes
Genes identified as potential deep ocean adaptations were searched for by inspection of the
SAG annotations, inspection of KEGG pathways on IMG, and BLASTP of homologs for the
various features against the SAR11 genomes. The fasta file containing these homologs is
available in Supplemental Information. The presence of 16S rRNA gene insertions was tested
by aligning all SAR11 16S sequences with those of known piezophiles carrying the insertions
(Lauro et al., 2007) using MUSCLE (Edgar, 2004), and manually inspecting the alignment.
CRISPR region analysis and cas gene search
Page 10 of 21
CRISPRs are annotated by IMG using the CRISPR recognition tool and PILER (see
http://img.jgi.doe.gov for more details). The designated AAA240-E13 CRISPR region was
further analyzed by examining reciprocal best BLAST hits (see “Metagenomics,” below) to those
coordinates (scaffold 14, bases 24207-26268). Sequences were identified as having recruited to
the corresponding coordinates of the single-scaffold AA240-E13 genome (Table S1) by use of
metagenome_index.pl. To build the local recruitment plot in Figure 7, these sequences were
aligned to the intergenic/CRISPR region with BLASTN with low-complexity filtering disabled.
Additionally, the entire region was searched against the IMG v400 custom protein database with
BLASTX on default settings to identify potential protein-coding regions. HMMs developed for a
wide range of cas protein families were developed by Haft et al. (Haft et al., 2005) and
Makarova et al. (Makarova et al., 2011), and made available through TIGRFAM
(http://www.jcvi.org/cgi-bin/tigrfams/index.cgi). Each of the 46 HMMs from Haft et al. Table 1
and the 32 additional HMMs from Makarova et al. Table S4 were searched against the proteincoding sequences from all four SAGs using hmmsearch (part of the HMMER3 package (Eddy,
2011)) on default settings. Only 8 HMMs returned any hits to the SAGs. Of those, only three had
hits in AAA240-E13. TIGR00372 had hits to hypothetical proteins in orthologous cluster
15001317. TIGR01587 had hits to type II DNA helicases conserved in all sequenced SAR11
genomes. TIGR03117 had hits to a RecG-like helicase, also conserved in all SAR11 genomes.
The remaining HMMs with hits in SAR11 had low scores and small alignment regions. All
positive search results are provided with our additional files.
Phylogenetics
SAG 16S rRNA gene sequences were combined with those of SAR11 strains in previously
established subclades (Grote et al., 2012, Morris et al., 2005, Vergin et al., 2013)
(SAG_reference.fasta). Sequences were aligned with MUSCLE (Edgar, 2004) using default
settings and the tree was created with RAxML (Stamatakis et al., 2008). Thirty seven
alphaproteobacterial and two outgroup 16S rRNA sequences were aligned with the subclade Ic
clone sequence from (Vergin et al., 2013) and those of the sequenced Ic SAGs. AAA240-E13
had two partial 16S rRNA gene fragments after assembly, and the larger of the two was used.
Alignments were performed with MUSCLE using default settings (Edgar, 2004), poorly aligned
positions were removed with Gblocks (Castresana, 2000) using the following settings:
–b1=(seqs/2)+1 –b2=(seqs/2)+1 –b3=seqs/2 –b4=2 –b5=h
The final tree was computed using RAxML (Stamatakis, 2006) using the following settings:
raxmlHPC-PTHREADS -x 1234 -T 4 -f a -m GTRGAMMA -\# 1000
Page 11 of 21
The phylogenomic tree of SAR11 strains was calculated as part of the Hal pipeline (Robbertse
et al., 2011, Thrash et al., 2011), in this case, using liberal Gblocks settings, maximumlikelihood (RAxML), and 10% allowed missing data, which resulted in a concatenated alignment
of 322 protein-coding genes (84,355 sites).
Because of the small length of the proteorhodopsin gene and difficulty with the
alignments using MUSCLE (data not shown), the combined, iterative alignment/phylogeny
program HandAlign was utilized for the proteorhodopsin phylogeny (Westesson et al., 2012).
Homologs were selected based on a BLASTP of the proteorhodopsin orthologs (cluster
1500536) in SAR11 against the IMG v350 protein gene database using default settings. Large
gene homologs were removed using the cluster_size_filter.pl script:
$ perl ~/scripts/cluster_size_filter.pl rhodopsin.tab 70 130
Eukaryotic
rhodopsin
homologs
were
removed
manually
as
well
as
those
from
HTCC2255/HTCC2999 as these constituted potential contaminants. The tree was calculated
using the following commands:
$ handalign clean_rhodopsins3.faa --hmmoc-root hmmoc -l 255 -ts 2000 -af
clean_rhodopsins3.trace.stk -ub > clean_rhodopsins3.MAP.stk
$ stocktree.pl clean_rhodopsins3.MAP.stk > clean_rhodopsins3.MAP.newick
Based on the results of (Grote et al., 2012), we knew distinction of the sarcosine
dehydrogenase (sardh) and dimethylglycine dehydrogenase (dmgdh) from within the same OC
(cluster 150013) required phylogenetic analysis. This was done using the bash script
protPipeline3, which automates a phylogenetic pipeline including alignment with MUSCLE
(Edgar, 2004), Gblocks editing of poorly aligned sites (Castresana, 2000), ProtTest amino acid
substitution modeling (Abascal et al., 2005), and maximum-likelihood tree construction using
RAxML (Stamatakis, 2006). The clusters formed based on the tree were designated
1500013.f.ok (dmgdh), 150013.f1.ok, 1500013.f2.ok, and 1500013.f3.ok (sardh).
All unaligned fasta files for each of the single gene trees and the super alignment and
model file for the concatenated protein tree provided in Supplemental Information. All tree labels
were manipulated using the Newick utilities (Junier and Zdobnov, 2010).
Metagenomics
Seven samples were collected at the BATS site (31° 40’ N, 64° 10’ W) during August 19, 2002
(0, 40, 80, 120, 160, 200, and 250 m). To collect the microbial biomass, ~ 70 L of seawater was
filtered through 0.2-µm polyethersulfone membranes (Supor, Pall, East Hills, NY, USA) using
McLane Research Laboratories, Inc. (East Falmouth, MA) in situ water transfer systems and
Page 12 of 21
membranes were stored at -80°C until further processing. Nucleic acids were extracted and
purified as described (Morris et al., 2005). Library construction and shotgun sequencing were
performed using a first-generation GS-FLX protocol (454 Life Sciences), yielding average read
lengths of 226 bp. BATS metagenomes and corresponding geochemical metadata are available
on CAMERA (http://camera.calit2.net) under the project ID CAM_PROJ_BATS. Data was also
analyzed from 454 metagenomic sequences collected from Station ALOHA (Shi et al., 2011),
the ETSP OMZ (Stewart et al., 2012), Puerto Rico Trench (Eloe et al., 2011a), the Sea of
Marmara (Quaiser et al., 2010), and the Matapan-Vavilov Deep in the Mediterranean Sea
(Smedile et al., 2013). All 454 metagenomic datasets were quality trimmed using lucy v1.2
(http://sourceforge.net/projects/lucy/) using a minimum good sequence length of 100bp and
default
error
settings.
Trimmed
reads
were
dereplicated
using
CD-HIT-454
v4.6.1
(https://code.google.com/p/cdhit/) with the following parameters: (-c 1.00 –n 8). Sanger
sequences from ALOHA (Konstantinidis et al., 2009), and the GOS (Rusch et al., 2007, Venter
et al., 2004), were also subjected to the reciprocal best blast protocol, below, but without
normalization due to their difference in read size. GOS sequences were first separated
according to sample, and individual databases were created for each; samples with
FILTER_MIN > 0.22 µm were excluded, as well as a single sample MOVE858 where
FILTER_MAX was 0.22 µm. GOS surface sequences from Antarctica and the Southern Ocean
(Brown et al., 2012) (Table S1) were dereplicated as above, but without quality trimming (no
fastq files were available). For these samples, all available size fractions were combined for
each sample. These were also excluded from gene centric normalization.
Comparative recruitment of metagenomic sequences was completed using a reciprocal
best BLAST (rbb). A total of 12 SAR11 genomes were included in the rbb- eight pure culture
genomes (HTCC1062, HTCC1002, HTCC9565, HTCC7211, HIMB5, HIMB114, IMCC9063,
HIMB59), and the four SAR11 SAGs. All incomplete SAR11 genome sequences were artificially
concatenated in the order presented by IMG, with a string of nine “N” at each scaffold break for
later identification of boundaries. The concatenated SAR11 genome sequences were searched
against each metagenome database with BLASTN on default settings. All hits to SAR11
genomes were then searched against the entire IMG database (v400), which had been
customized to contain only these 12 SAR11 genome sequences (others have been completed
and deposited since this analysis began) using BLASTN on default settings except –
max_target_seqs, set to 100000000, to allow for inclusion of all possible hits. Amino acid and
nucleotide versions of this database, IMG v400 custom, were used in the average genome size
and relative abundance calculations, respectively, below. Best hits from the second BLASTN
Page 13 of 21
(reciprocal best hits- rbh) to the 12 SAR11 sequences were plotted with fragment_recruiter.r.
Localization of each rbh to each gene in the SAR11 genomes was completed using the script
metagenome_index.pl. Gene coordinates were established for each genome fasta using the
gene coordinate workflow available in Supplemental Information. The gene coordinates for the
concatenated SAGs is recorded in Table S1 under the tabs Start Coord (single) and End Coord
(single). For relative abundance estimates of SAR11 in a given dataset, each set of 454
metagenomic sequences by sample was searched against the entire IMG v400 custom genome
database using megablast with default settings. Best hits were then counted as either SAR11like or non SAR11-like, based on whether they recruited to any of the 12 SAR11 genomes or
not, respectively.
Investigating enrichment of SAR11 gene clusters at depth in metagenomic samples
A
complete
description
of
methods
can
be
found
in
the
supplementary
file
‘Statistical_analyses.pdf’. This document was generated with a runnable Sweave script, which is
available on the Giovannoni GitHub repository (git@github.com:giovannoni-lab/bathytype.git).
Briefly, metagenomes were classified as ‘surface’ (<200m) or ‘deep’ (≥200m) and the
abundance of gene clusters as determined by reciprocal best-BLAST (see above) in each
dataset was calculated. To identify statistically significant differences in gene cluster abundance
between deep and surface samples, the R package DESeq (Anders & Huber, 2010) was used
to correctly account for over-dispersion typically associated with gene abundances in high
throughput sequencing studies. To validate the a posteriori classification of ‘deep’ and ‘surface’
samples, blind estimation of dispersion followed by clustering analysis of samples was
performed. This analysis showed the MATA, MARM, PRT and CHOMZ.800 samples did not
cluster correctly with other ‘deep’ samples. Therefore, DESeq analysis was performed both
against the complete dataset and a subset with samples MATA, MARM, PRT and CHOMZ.800
removed.
Investigating SAR11 Ic subclade abundance as a function of temperature
A
complete
description
of
methods
can
be
found
in
the
supplementary
file
‘Statistical_analyses.pdf’. This document was generated with a runnable Sweave script, which is
available on the Giovannoni GitHub repository (git@github.com:giovannoni-lab/bathytype.git).
To determine if increased SAR11 Ic abundance at depth was a result of an adaptation to lower
temperatures, SAR11 Ic abundance and total SAR11 abundance was calculated in 91 GOS
samples by reciprocal best-BLAST (see above). Negative binomial regression GLM analysis
Page 14 of 21
was then applied to the data, using the total SAR11 counts as an offset. As the data consisted
of different sequencing types (Sanger and 454), the sequencing type was included as a factor in
the model. Model terms were sequentially dropped to test each term for significance.
Sequencing type was shown to not be a significant regression factor and so was dropped from
the model. The resultant model was then compared to the null model and the Nagelkerke
coefficient of determination (Nagelkerke, 1991) was calculated.
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Supplementary Figures
Figure S1. Maximum-likelihood tree of 16S rRNA genes for the SAR11-type SAGs used for
initial selection of SAGs for genome sequencing. Outgroup is R. prowazekii; bootstrap values
(n=100) are indicated at the nodes; scale bar indicates 0.3 changes per position.
Figure S2. Recruitment plots of reciprocal best hit metagenomic sequences for Station ALOHA,
by genome. Colors indicate depth. Y-axes: % identity; x-axes, genome length.
Figure S3. Recruitment plots of reciprocal best hit metagenomic sequences for the Eastern
Tropical South Pacific Oxygen Minimum Zone, by genome. Colors indicate depth. Y-axes: %
identity; x-axes, genome length.
Figure S4. Recruitment plots of reciprocal best hit metagenomic sequences for BATS, by
genome. Colors indicate depth. Y-axes: % identity; x-axes, genome length.
Figure S5. Recruitment plots of reciprocal best hit metagenomic sequences for the Puerto Rico
Trench, by genome. Y-axes: % identity; x-axes, genome length.
Figure S6. Recruitment plots of reciprocal best hit metagenomic sequences for the Sea of
Marmara, by genome. Y-axes: % identity; x-axes, genome length.
Figure S7. Recruitment plots of reciprocal best hit metagenomic sequences for the MatapanVavilov Deep, by genome. Y-axes: % identity; x-axes, genome length.
Figure S8. Recruitment plots of reciprocal best hit Sanger sequenced metagenomic sequences
for Station ALOHA at 4000 m, by genome. Y-axes: % identity; x-axes, genome length.
Figure S9. Boxplot of COG distributions between surface (red) and subclade Ic genomes (“sag”,
blue). Boxes indicate the upper and lower quartile, with the median as a black bar, error bars
indicate adjacent values, and open circles indicate outside values. Orange boxes highlight COG
categories with non-overlapping distributions.
Figure S10. Relative abundance of amino acids based on their classification as similar or
different amino acid substitutions.
Page 19 of 21
Figure S11. Analysis of intergenic space. Distributions of intergenic spaces are plotted in
histograms for A) all surface genomes and B) all Ic genomes, with an x-axis limit of 1000. Box
plots of the same data, C) including outliers and D) excluding outliers to more easily view the
median values. Wilcoxon rank sum results are reported in C.
Figure S12. Putative partial pathway for purine degradation in subclade Ic (taken from KEGG).
Enzymes for each transition are labeled, along with the corresponding OC from this analysis,
and colored according to the key. The uncolored S-allantoin amidohydrolase indicates no
matching annotations in any of the genomes. Gene organization on AAA240-E13 is depicted in
the upper right. Note that the xanthine dehydrogenase clustered with the aerobic carbon
monoxide dehydrogenase large subunit genes (Table S1), but we expect this was because they
are part of a larger molybdenum hydroxylase family (Dobbek et al., 1999), and not true
orthologs in this case. Although present in AAA288-E13 and AAA288-N07, the adenosine
deaminase was missing in AAA240-E13 and therefore not included in the gene neighborhoods.
Figure S13. Relative abundance of orthologous clusters (OCs) by depth and location according
to number of reciprocal best blast hits in that sample. Each heat plot contains all OCs found in
the pan-genome (x-axis) of the 12 genomes analyzed (y-axis). Colors (blue to white to red)
indicate increasing relative abundance, according to each plot-specific scale. Relative
abundance of OCs for each genome was used to calculate Bray-Curtis dissimilarities and
hierarchically clustered using unweighted pair group method with arithmetic mean (UPGMA). All
descendent links below a cluster node k share a color if k is the first node below the cut
threshold of 0.7 × maximum cluster difference (default matplotlib/MATLAB behavior for
dendrograms). Red boxes highlight samples where the sublclade Ic SAGs grouped together
hierarchically based on gene recruitment patterns. ALOHA- Station ALOHA, ESTP OMZEastern Subtropical Pacific Oxygen Minimum Zone, BATS- Bermuda Atlantic Time-series Study
site, MARM- Sea of Marmara, PRT- Puerto Rico Trench, MATA- Matapan-Vavilov Deep.
Figure S14. Bayesian phylogenetic analysis of proteorhodopsin sequences using HandAlign.
SAR11 proteorhodopsins are highlighted in red, along with subclade designations. Scale bar
indicates changes per position.
Page 20 of 21
Figure S15. Circos plot of SAG genomes, arranged by scaffold length in descending order.
Outer ring: GC content. Center ring: scaffolds proportionate to size. Inner ring: predicted genes
colored according to OC category: blue- true core; green- potential core; orange- shared Ic; redunique Ic; black- rRNA/tRNA; uncolored- remaining distributions. Additionally, shared Ic clusters
are connected by lines of the same color.
Figure S16. MUSCLE alignment of the 16S rRNA gene for genome-sequenced SAR11 strains,
including the SAGs, as well as sequences with known insertions from (Eloe et al., 2011b, Lauro
et al., 2007) for comparison.
Supplementary Table
Table
S1.
Excel
spreadsheet
(Table_S1_F.xlsx)
of
the
comparative
genomics
metagenomics data for the SAR11 subclade Ic SAGs.
Page 21 of 21
and
Figure S1
ref. sequences w/out cultured representatives
genome-sequenced representatives
SAGs selected for sequencing
Maine
Mediteranean
Surface
Mesopelagic
Subclade Ia
Subclade Ib
“Subclade Ic”
Subclade II
Subclade IIIa
0.3
Subclade V
Figure S2
Figure S3
Figure S4
Figure S5
Figure S6
Figure S7
Station ALOHA 4000m Sanger shotgun sequences
90
60
70
80
70
80
90
90
80
70
AAA288−N07
100
AAA288−G21
100
100
AAA288−E13
60
60
70
80
90
100
AAA240−E13
60
Figure S8
955384
637000375_HTCC1062
638371090_HTCC1002
2503290285_HTCC9565
2503290180_HTCC7211
80
70
60
60
60
70
70
80
90
100
90
90
80
90
80
70
60
100
911028
100
813817
100
1402975
1456888
2503985354_HIMB5b
2503290182_HIMB114
2505679264_IMCC9063
2503985355_HIMB59b
80
60
60
1237371
4000m rev
70
80
70
70
60
4000m fwd
90
100
90
90
80
90
80
70
60
1343202
100
1279701
100
1323004
100
1308759
1284727
1410127
E.sag
E.surface
G.sag
G.surface
D.sag
D.surface
N.sag
N.surface
M.sag
M.surface
B.sag
B.surface
H.sag
H.surface
Z.sag
Z.surface
V.sag
V.surface
C.sag
C.surface
S.sag
S.surface
R.sag
R.surface
P.sag
P.surface
U.sag
U.surface
I.sag
I.surface
F.sag
F.surface
O.sag
O.surface
L.sag
L.surface
Q.sag
Q.surface
T.sag
T.surface
K.sag
K.surface
J.sag
J.surface
0
5
10
Percentage of genes
15
Figure S9
B
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
Met
Asn
Pro
Gln
Arg
Ser
Thr
Val
Trp
X
Tyr
gap
More in the surface
Similar a.a. substitutions
More in the SAGs
More in the surface
A
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
Met
Asn
Pro
Gln
Arg
Ser
Thr
Val
Trp
X
Tyr
gap
More in the SAGs
Figure S10
Different a.a. substitutions
Figure S11
A
B
SAR11 Ic intergenic sizes
100
80
0
0
20
50
40
60
intergenic length
150
100
intergenic length
200
120
250
140
surface SAR11 intergenic sizes
0
200
400
600
800
0
200
Frequency
600
800
Frequency
D
SAR11 intergenic spacer distribution
SAR11 intergenic spacer distribution (no outliers)
250
C
400
200
150
100
length
2000
50
1000
0
length
3000
Wilcoxon rank sum results
W = 4905338
p-value = 4.506e-06
95% confidence interval:
-7.000018 -2.999993
difference in location
(surface vs. Ic):
-5.000034
surface
Ic
surface
Ic
Figure S12
Allantoicase
Xanthine
Xanthine
dehydrogenase
1500887
1500965
Putative urate
catabolism protein
Ureidoglycolate
hydrolase
AAA240-E13 Scaffold 7
OHCU
decarboxylase
Urate
Putative urate
catabolism protein ?
15001376
Cytosine/uracil/thiamine/allantoin
permeases
Xanthine
dehydrogenase SSU
Xanthine
dehydrogenase
Cytosine/adenosine
deaminase
AAA240-E13 Scaffold 13
5-hydroxyisourate
OHCU
Hydroxyisourate hydrolase
15001369
subclade Ic only
subclade Ic and other SAR11
OHCU
15001217
S-allantoin
Allantoate
2-oxo-4-hydroxy-4-carboxy5-ureidoimidazoline
OR
5-hydroxy-2-oxo-4-ureido2,5-dihydro-1H-imidazole5-carboxylate
OHCU decarboxylase
S-allantoin amidohydrolase
Hydroxyisourate
hydrolase
Allantoicase
15001375
Ureidoglycolate hydrolase
Ureidoglycolate
Urea
15001374
NH3 + CO2
_41246
_DSM M_7
_H-43 _DS
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psin_M
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rhodo
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rhod
Ftrac_
643_
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64978
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952
6464
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CC
Figure S15
Figure S16
Alignment: /Users/jozenn/Documents/Giovannoni Lab/Projects/SAGs/Results/16S_tree_for_ms/piezo16s_cln_al.fna
Seaview [blocks=10 fontsize=6 LETTER] on Tue Jan 8 09:20:25 2013
1
---------------------------------------------------------------------------------------CCCT
------CCCT
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ACTTTAATTG
----------------------------------------------------------------------------------------------------------------------------------TAACTT
-------------------------------------------------------------------------
---------------------------------------------------------------------------------TAGAGTTTGA
TAGAGTTTGA
----------------------GTTTGA
-------AAA
-----------GAGTTTGA
----GTTTGA
--GAGTTTGA
--GAGTTTGA
--GAGTTTGA
----GTTTGA
----GTTTGA
--GAGTTTGA
----GTTTGA
--GAGTTTGA
--GAGTTTGA
--GAGTTTGA
--GAGTTTGA
--GAGTTTGA
-------------------------------------------TGA
AAGAGTTTGA
----------TGAGTTTGA
----------------------------AGAGTTTGA
-------------------------------------------------------AGAGTTTGA
-AGAGTTTGA
GAGAGTTTGA
-AGAGTTTGA
----------AGAGTTTGA
-------------------AGAGTTTGA
----------AGAGTTTGA
---------------------------------------------------------------------------------TCATGGCTCA
TCATGGCTCA
------------------TCATGGCTCA
TCATGGCTCA
---------TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
------------------------------------TCCTGGCTCA
TCATGGCTCA
---------TCCTGGCTCA
----GGCTCA
-----------ATGGCTCA
TCCTGGCTCA
-----------ATGGCTCA
--ATGGCTCA
--ATGGCTCA
-----------ATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
TCATGGCTCA
-----GCTCA
TCATGGCTCA
------------------TCATGGCTCA
--ATGGCTCA
TCATGGCTCA
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
--TTGAACGC
GATTGAACGC
GATTGAACGC
----GAACGC
---------GATTGAACGC
GATTGAACGC
---------GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
GATTGAACGC
------------------------------------GATTGAACGC
GATTGAACGC
---------C
GGACGAACGC
GAACGAACGC
--ACGAACGC
GAACGAACGC
GAACGTACGC
-AACGTACGC
GAACGTACGC
GAACGTACGC
GAACGTACGC
---------GAACGTACGC
GAACGTACGC
GAACGTACGC
GAACGTACGC
GAACGTACGC
GGACGTACGC
GAACGTACGC
-AACGTACGC
-AACGTACGC
GAATGTACGC
GAACGTACGC
GAACGTACGC
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
----GGCAGG
TGGCGGCAGG
TGGCGGCAGG
---CGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
TGGCGGCAGG
------------------------------------TGGCGGCAGG
TGGCGGCAGG
TGGCGGCATG
TGGCGGCATG
TGGCGGCACG
TGGCGGCAGG
TTGCTGCATG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
---------TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACTGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
TGGCGGCACG
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CTTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
--TTACACAT
---------------------------CCTAACACAT
CCTAACACAT
C-TAATACAT
CCTAATACAT
CCTAACACAT
CCTAACACAT
CTTTATACAT
CTT-ATACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
---------CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CGTTATACAT
CCTTATACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
CCTAACACAT
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
-------------------------GAG
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
---------GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAA
GCAAGTCGAG
GCAAGTCGAG
GCAAGTCGAG
CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACA-CGGTAACATCGGTAACA-CGGTAACA-CGGTAACA-CGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGTAACAGCGGAAACG-------------------CGGAAACAGCGGAAACAGCGGAAACAGCGCTTTAATT
CGCTTTAATT
C--------CG-------CGAAGGCCCC--------CG----CAGC--------C--------C-----------------C--------C--------C--------C--------C--------C--------C--------C--------C--------C--------C--------C---------
------GAGA
------GAGA
------GAGA
------GAGA
------GAGA
------GAGA
------GAGA
------GAGA
------GAGA
------GAAC
------TAAA
------GAGA
------GAGA
------GAAT
------GAAT
------GAAT
------GGAT
------GAAT
------GAAG
------GAAT
------GAAG
------GAAT
------GAAT
------GAAT
------GAAT
------GAAT
------GAAT
------GAAT
------GAAT
------GAAT
------AAGA
------------------------GAAG
------GAAG
------GAAG
TCACCGGGTG
TCACCGGGTG
---------------------------------GCAG
---------------GAAG
------GAAG
------GAAG
---------------GAAG
------GAAG
------GAAG
------GAAG
------GAAG
------GAAG
------GAAG
------GCAG
------GCAG
------GAGG
------GGGG
------GAGG
-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGCCTAGCTTGCGTAGCTTGCGTAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGCGAAGCTTGCT
-TAGCTTGCAAAGCTTGCT
-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGC-TAGCTTGCATAGCTTGC-------------------GTGCTTGC-GTGCTTGC-GTGCTTGCCTTGCACCCCTTGCACCC---GCTT---CGCCTT---TAGCTTGCT
-TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA------------TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA---TAGCAA---TACTTG---TAGCAA---TAGCAA---
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TA-TCTGCTG
TAGTTTGATG
TAGTTTGATG
TACTTTGCTG
TACTTTGCTG
TAATTCGCTG
TAATTTGCTG
TAATTCGCTG
TAATTCGCTG
TAATTCGCTG
TTCTTTGCTG
TAATTTGCTG
TTCTTTGCTG
TAATTTGCTG
TAATTTGCTG
TAATTCGCTG
TAATTCGCTG
TAATTTGCTG
TAATTTGCTG
TAATTTGCTG
TAATTTGCTG
TAATTCGCTG
TATTCTGGCG
------------------ACCTTTGCTG
ACCTTTGCTG
ACCTTTGCTG
ATCGAAGTTA
ATCGAAGTTA
TCCTTCGGGA
-------CGG
AGGTGTCCT--------TA
--------TA
--------TA
--------TA
--------TA
-----------------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
--------TA
111
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGTGGCG
ACGAGTGGCG
ACGAGTGGCG
ACGAGTGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
ACGAGCGGCG
TCGAGCGGCG
------------------TCGAGCGGCG
TCGAGCGGCG
TCGAGCGGCG
AGGAGTGGCG
AGGAGTGGCG
AGGAGCGGCG
GCGAGCGGCG
--TAGTGGCG
CTGAGTGGCA
CTGAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
---------CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTTAGTGGCA
CTGAGTGGCA
CTGAGTGGCA
CCTAGCGGCA
CCTAGCGGCA
CCTAGCGGCA
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
----GGTGAG
-ACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTTAG
GACGGGTTAG
CACGGGTGAG
GACGGGTGAG
AACGGGTGAG
AACGGGTGAG
AACGGGTGAG
GACGGGTGAG
---------GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGAG
GACGGGTGCG
GACGGGTGCG
GACGGGTGCG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCTTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCCTGG
TAATGCTTGG
TAATGCCTAG
TAATGCCTAG
TAATGCCTAG
TAATGCCTAG
TAATGCCTAG
TAACACGTGG
TAACACGTGG
TAACGCGTGG
TAACGCGTGG
TAACACGTGG
TATAATGTGG
TATAATGTGG
TAATATGTGG
TAATATGTGG
TAATATGTGG
---------TAACATGTAG
TAACATGTAG
TAACATGTGG
TAACATGTGG
TAACATGTGG
TAACATGTAG
TAACATGTGG
TAACATGTGG
TAACATGTGG
TAACATGTGG
TAACATGTGG
TAACATGTGG
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATATGCC
G-AATCTGCC
G-GAACTGCC
G-GAACTGCC
G-GAACTGCC
G-GAACTGCC
G-GAACTGCC
GTAACCTGCC
GTAACCTGCC
G-AACATACC
G-AACGTGCC
G-AACATACC
G-AATCTGCC
G-AATCTGCC
G-AATCTGCC
G-AATCTGCC
G-TATCTACC
---------G-TATCTGCC
G-TATCTGCC
G-TATCTACC
G-TATCTACC
G-TATCTACC
G-TATCTTCC
G-TATCTTCC
G-AATCTGCC
G-AATCTGCC
G-AATCTGCC
G-AATCTGCC
G-AATCTGCC
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTATGGTGGG
TTGGAGTGGG
TTGGAGTGGG
TTAACGTGGG
TTAACGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TTAGTGTGGG
TAGTCGAGGG
CAGTCGAAGG
CAGTCGAGGG
CAGTCGAGGG
CAGTCGAGGG
CAGTCGAGGG
CATAAGAGGG
CATAAGAGGG
CATCACTAAG
CAGATCTACG
TCATAGTACG
TTTTGGTTTG
TTTTGGTTTG
CTTCGGTCTG
CTTCGGTCTG
TTTCGGTCTG
---------CTTTGGCCTG
CTTTGGCCTG
CTTTGGCCTG
CTTTGGCCTG
CTTTGGCCTG
CTTTGGTGAG
CTTTGGTGAG
TTGTGGTTCA
TTGTGGTTCA
TTTTGGTTCG
TTTTGGTTCG
TTTTGGTTCG
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGACAACAGT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGATAACTAT
GGACAACAGT
GGATAACAGT
GGATAACAGT
GGATAACAGT
GGATAACAGT
GGATAACAGT
GGATAACATT
GGATAACATT
GAATAGCCTC
GAATAGCCAC
GAATAACTGC
GAATAACTCG
GAATAACACG
GAATAACACG
GAATAACATG
GAATAACATG
---------GAATAACACG
GAATAACACG
GAATAACACG
GAATAACACG
GAATAACACG
GAATGACACG
GAATAACACG
GGACAACATT
GGACAACATT
GAACAACATG
GAACAACATG
GAATAACACG
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAT
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
TGGAAACGAC
CGGAAACGGA
CGGAAACGGA
GGGAAACTGA
TGGAAACGGT
GGGAAACTGT
GGGAAACTTG
GGGAAACTTG
AGGAAACTTG
AGGAAACTTA
GGGAAACTTA
---------AGGAAACTTG
AGGAAACTTG
AGGAAACTTG
AGGAAACTTG
AGGAAACTTG
AGGAAACTTG
AGGAAACTTG
GGGAAACCGA
GGGAAACCGA
GGGAAACCTG
GGGAAACCTG
GGGAAACCTG
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
AGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
GAGTAATACC
GAGTAATACC
AGCTAATACC
AGCTAATACC
TGCTAATACC
CGCTAATACC
TGCTAATACC
TGCTAATACC
---------TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACC
TGCTAATACT
TGCTAATACT
TGCTAATACC
TGCTAATACC
TGCTAATACC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTG
G-ATAACGTG
GCATAATGTC
GCATAATGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAATGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATAACGTC
GCATACGACC
GCATACGCTGCATACGCCC
GCATACGCCC
GCATACGCCC
GCATACGCCC
GCATATTTCT
GCATATTTCT
TTATACGCCC
GTATACGCCC
GTATATT--GGATAAGCCC
GAATAAGCCC
GGATAAGCCT
GGATAAGCCT
GGATAAGCCT
---------AGATAAGTCT
GGATAAGTCT
GGATAAGTCT
GGATAAGTCT
GGATAAGTCT
TCATAAGTCT
TCATAAGTCT
GGATAAGCCC
GGATAAGCCC
GGATAAGTCC
GGATAAGTCC
GGATAAGTCC
T--------T--------T--------T--------T--------T--------T--------T--------T--------CTT--TTTGT
CTT--TTTGT
T--------T--------TTTG-TTCAT
T--------T--------CTTG-TTCAT
T--------CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
CTTG-TTCAT
T--------T--------T-----------------T--------T--------T--------T--------AATCGTCTCC
AATCGTCTCC
T--------T-----------------TTAC-----TTAC-----TTAC-----TTAC-----TTAC--------------TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----TTAC-----T--------TTAC------
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
AGTGAAAAGT
AGTGAAAAGT
------ACGG
------ACGG
TACGAGCGGG
------TCGG
------TCGG
TACGAGCGGG
------TCGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
TACGAGCGGG
------TCGG
------TCGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
------ACGG
TGACGAATGG
TGACGAATGG
------TCGG
------TCGG
------------------G
---------G
---------A
---------A
---------A
------------------G
---------G
---------G
---------G
---------G
---------G
---------G
---------G
---------G
---------G
------AACG
---------G
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
221
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGGGG
ACCAAAGCAG
ACCAAAGCAG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
ACCAAAGAGG
GTGAAAGGGG
GGGAAAGGAG
GGGAAAGGAG
GGGAAAGGAG
GGGAAAGGAG
GGGAAAGGAG
AAGAAAGGTG
AAGAAAGGTG
GGGAAAG--GGGAAAG---CCAGAAATG
GGGAAAG--GGGAAAG--GGGAAAG--GGGAAAG--GGGAAAG-----------GAGAAAG--GAGAAAG--GAGAAAG--GAGAAAG--GAGAAAG--GAGAAAG--GAGAAAG--GGGAAAG--GGGAAAG--GAGAAAG--GAGAAAG--GAGAAAG---
GGGA-----T
GGGA-----T
GGGA-----T
GGGA-----T
GGGA-----T
GGGA----TT
GGGA----TT
GGGA----TT
GGGA----TT
GGGA-----T
GGGA-----T
GGGA-----C
GGGA-----C
GGGA-----A
GGGA-----C
GGGA-----C
GGGA-----A
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GGGA-----C
GCC------T
GGGA-----GGGACGCGCT
GGGACGCGTT
GGGACGCGCT
GGGACGCGTT
G--------G--------------------------GGAA-----------------------T
---------C
---------C
---------C
---------------------------------------------C
------------------C
---------C
------------------T
---------------------------T
CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----TCTTGTTTTT
CTTC-----CTTC-----CCTTGTTTTT
CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----CTTC-----TTTC-----TTTC-----TTTT-----TTTC-----CTTC-----CTTC--------------------------------CTTT-----TTTA-----TTTA-----TTTA-----TTTA--------------CTTT-----CTTT-----CTTT-----TTTA-----CTTT-----TTTA-----TTTA-----TTTT-----TTTA--------------TTTT-----TTTA------
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
CGAAACAGGG
--------GG
--------GG
CGAAATGGGG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
--------GG
------TTGA
---------G
---CAATGTG
----GAAGTG
---CGAAGTG
----GAAGTG
--------------------------------------------AG
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
-ACCTCTCGC
-ACCTCTCGC
-ACCTCTCGC
-ACCTCTCGC
-ACCTCTCGC
AACCTCTCGC
AACCTCTCGC
AACCTCTCGC
AACCTCTCGC
-ACCTCCCGC
-ACCTCTCGC
-GCCTTGCGC
-GCCTTGCGC
-TCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-TCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTTTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
-GCCTCTCGC
AAGCTCTCGC
CGCCTTTCGC
CGCCTTTCGC
CGCCTTTCGC
CGCCTTTCGC
CGCCTTTCGC
-GGCTACCGC
-GGCTACCGC
-ATTTATCGG
-ATTTATCGG
-ATTTATCGC
----ATGCGC
------ACGC
-----TGCTC
-----TGCTC
-----TGCTC
-------------ATGCAC
----ATGCAC
----ATGCAC
-----TGCAC
----ATGCAC
-----TGCGC
-----TGCGC
-----AATGC
------ATGC
-ATTTATCGC
-----AATGC
------ATGC
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
CATTTGATTA
TTCTTGATTA
CTCTTGATCA
GTTTAGAGTA
GTTTAGAGTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GCTAAGATTA
GACTAGATGA
GATTGGATGT
GATTGGATGT
GATTGGATGT
GATTGGATGT
GATTGGATGT
TTATGGATGG
TTATGGATGG
TGATGGATTG
ATTTGGATCG
TATGAGATTG
CGAAAGATGA
CGAAAGATGA
CGATGGATGA
CGATTGATGA
CGATAGATGA
---------CATTGGATGA
CATTGGATGA
CAATGGATGA
CATTGGATGA
CATTGGATGA
CGAAGGATGA
CAATGGATGA
CATAAGATGA
CATAAGATGA
CGAAAGATGA
CAAAAGATGA
CAAAAGATGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGA
GCCCAAGTGG
GCCCAAGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAGGTGG
GCCCAAGTGG
ACCTAGGTGG
ACCTAGGTGG
ACCTAGGTGG
ACCTAGGTGG
ACCTAGGTGG
ACCCGCGGCG
ACCCGCGGCG
GCCCGCGTAA
GCCCGCGTTA
GCCCGCGCAA
GCCCGCACTT
GCCCGCACTT
GTCCACACTT
GCCCACACTT
GTCCACACTT
---------GCCTGCACTT
GCCTGCACTT
GCCCGCACTT
GCCCGCACTT
GCCCGCACTT
GCCTGCACTT
GCCCGCACTT
GCCCGCATTT
GCCCGCATTT
GCCCGCACTA
GCCCGCATTT
GCCCGCATTT
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTTG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
GATTAGCTAG
TATTAGCTAG
TATTAGCTAG
GATTAGATAG
GATTAGGTAG
GATTAGCTTG
GATTAGCTCG
GATTAGCTAG
GATTAGTTAG
GATTAGTTAG
GATTAGTTAG
---------GATTAGTTTG
GATTAGTTTG
GATTAGTTTG
GATTAGTTTG
GATTAGTTTG
GATTAGTTTG
GATTAGTTTG
GATTAGTTAG
GATTAGTTAG
GATTAGCTTG
GATTAGCTTG
GATTAGTTTG
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTAAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGGGGT
TTGGTGGGGT
TTGGTAAGGT
TTGGTGAGGT
TTGGTAAGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTGAGGT
---------TTGGTGGGGT
TTGGTGGGGT
TTGGTAGGGT
TTGGTAGGGT
TTGGTAGGGT
TTGGTGGGGT
TTGGTGGGGT
TTGGTGAGGT
TTGGTGAGGT
TTGGTAAGGT
TTGGTGAGGT
TTGGTGAGGT
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AATGGCTCAC
AAAGGCTTAC
AAAGGCTTAC
AATGGCTTAC
AATGGCTTAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAAGGCTCAC
AAGAGCTCAC
AATGGCTTAC
AATGGCTTAC
AATGGCTTAC
AATGGCTTAC
AATGGCTTAC
AATGGCTCAC
AATGGCTCAC
AACGGCCTAC
AACGGCCTAC
AACGGCTTAC
AATGGCTCAC
AAAAGCTTAC
AAAAGCTCAC
AATAGCTCAC
AATAGCTCAC
---------AATAGCCTAC
AATGGCCTAC
AATGGCCTAC
AATGGCCTAC
AATGGCCTAC
AATGGCCTAC
AATGGCCTGC
AATGGCTCAC
AATGGCTCAC
AAAAGCTTAC
AAAAGCTCAC
AATGGCTCAC
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCAACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGACG
CAAGGCGATG
CAAGGCGATG
CAAGTCGACG
CAAGCCTACG
CAAGGCTCCG
CAAGGCAACA
CAAGGCAATG
CAAGACAATG
CAAGACAATG
CAAGACAATG
---------CAAGACTATG
CAAGACTGTG
CAAGACTATG
CAAGACTATG
CAAGACTATG
CAAGACTTTG
CAAGACTTTG
CAAGACAATG
CAAGACAATG
CAAGGCTACG
CAAGGCTATA
CAAGACTACA
331
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCTCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATCCCTAGCT
ATACGTAGCC
ATACGTAGCC
ATCTTTAGCT
ATCTATAGCT
ATCTTTAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
---------ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCTATAGCT
ATCAATAGCT
ATCAATAGCT
ATCAATAGCT
ATCTATAGCT
ATCAATAGCT
ATCAATAGCT
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TTTGAGA
GG-TCTTAGA
GG-TCTTAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GG-TCTGAGA
GA-CCTGAGA
GACCCTGAGA
GG-TTTGAGA
GG-TTTTAGA
GG-TTTGAGA
GT-TCTTAGA
GT-TCTTAGA
GA-TTTGAGA
GA-TTTGAGA
GA-TTTGAGA
---------GA-TTTGAGA
GA-TTTGAGA
GA-TTTGAGA
GA-TTTGAGA
GA-TTTGAGA
GA-TCTGAGA
GA-TCTGAGA
GA-TCTGAGA
GA-TCTGAGA
GA-TTTGAGA
GA-TTTGAGA
GA-TTTGAGA
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGACCAG
GGATGACCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGGTGATCGG
GGGTGATCGG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGAAGACCAT
GGAAGACCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
---------GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
GGATGATCAG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGA
CCACACTGGG
CCACACTGGG
CAACACTGGG
CAACACTGGG
CCACACTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
---------CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACATTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
CCACACTGGG
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
---------ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGACAC
ACTGAGATAC
ACTGAGATAC
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGTCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
---------GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
GGCCCAAACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
GGCCCAGACT
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGGG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCCAGGGGGG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
---------CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
CCTACGGGAG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTAG
GCAGCAGTAG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTAG
GCAGCAGTAA
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
---------GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTAG
GCAGCAGTAG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GCAGCAGTGG
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATATTGC
GGAATCTTCC
GGAATCTTCC
GGAATCTTAG
GGAATCTTGG
GGAATATTGG
GGAATCTTTC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
---------GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GAAACATTGC
GGAATATTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
GGAATCTTGC
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGAGG
ACAATGGAGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGAGG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
ACAATGGGCG
GCAATGGACG
GCAATGGACG
ACAATGGGCG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGGG
ACAATGGGAG
ACAATGGGGG
ACAATGGGGG
---------ACAATGGAGG
ACAATGGAGG
ACAATGGAGG
ACAATGGAGG
ACAATGGAGG
ACAATGGAGG
GCAATGGAGG
ACAATGGAGG
ACAATGGAGG
ACAATGGAGG
ACAATGGGCG
ACAATGGGCG
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAAGCCTGAT
AAACTCTGAT
AAACTCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACTCTGAT
CAAGCCTGAT
CAAGCCTGAT
CAAGCCTGAT
CAAGCCTGAT
CAAGCCTGAT
AAAGTCTGAC
AAAGTCTGAC
CAAGCCTGAT
CAACCCTGAT
AAACCCTGAT
AAACCCTGAT
AAACCCTGAT
CAATCCTGAT
AAACCCTGAT
AAACCCTGAT
---------AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAACTCTGAT
AAAGCCTGAT
AAAGCCTGAT
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
441
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGT
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATAC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GCAGCCATGC
GGAGCAATGC
GGAGCAATGC
CTAGCGATGC
CCAGCCATGC
CCAGCAATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
---------GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGGGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
GCAGCGATGC
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTATG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGTGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
AGCGTGAGTG
CCCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
---------CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
CGCGTGAGTG
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCT
AA-GAAGGCT
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGTT
AA-GAAGGTT
AT-GAAGGTC
AA-GAAGGCC
AC-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
---------AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AAGGAAGGCC
AA-GAAGGAC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
AA-GAAGGCC
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTAGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGGTTGT
TTCGGATCGT
TTCGGATCGT
TTAGGATCGT
CTAGGGTCGT
TTAGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
CTTGGGTTGT
CTTGGGTTGT
TTTGGGTTGT
---------CTTGGGTTGT
CTTGGGTTGT
CTTGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
TTCGGGTTGT
CTTGGGTTGT
TTTGGGTTGT
TTTGGGTTGT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGTACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAGCACTTT
AAAACTCTGT
AAAACTCTGT
AAAGCTCTTT
AAAACTCTTT
AAAACTCTTT
AAAACTCTTT
AAAACTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAACTCTTT
---------AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
AAAGCTCTTT
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGTTGTGAG
CAGCGAGGAG
CAGCGAGGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGTCGTGAG
CAGCGAGGAG
CAGCGAGGAG
CAGCGAGGAG
CAGCGAGGAG
CAGCGAGGAG
CAGCGAGGAG
TGTTAGAGAA
TGTTAGAGAA
CGCCAGGGAT
CGCCTGTGAT
CATCGGTGAG
CGTGGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGAGGAA
---------CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
CGTCGGGGAA
TGTAGGGGAA
TGTAGGGGAA
TGTCGGGAAA
TGTCGGGAAA
TGTCGGGAAA
GAA-AGGAGT
GAA-AGGAGT
GAA-AGGAGT
GAA-AGGAGT
GAA-AGGAGT
GAA-AGGGGT
GAA-AGGGGT
GAA-AGGGGT
GAA-AGGGGT
GAA-AGGTGG
GAA-AGGTGG
GAA-AGGGTA
GAA-AGGGTA
GAA-GGGTAT
GAA-GGGTGT
GAA-GGGTGT
GAA-GACATT
GAA-GACATT
GAA-GGGTGT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-GATTAT
GAA-AGGTAG
GAA-AGGTTG
GAA-AGGTTG
GAA-AGGTTG
GAA-AGGTTG
GAA-AGGTTG
GAACAAGGAT
GAACAAGGAT
GAT-AA---GAT-AA---GAT-AA---GAA-AA---GAA-AA---GAA-AA---GAA-AA---GAA-AA------------GAA-AA---GAA-AA---GAA-AA---GAA-AA---GAA-AA---GAA-AA---GAA-AA---GAT-AA---GAT-AA---GAT-AA---GAT-AA---GAT-AA----
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
TGATTTAATA
ACGTTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
GTAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
ACAGTTAATA
TAAATTAATA
TATGTTAATA
TAGTTTAATA
TAGTTTAATA
TAGTTTAATA
TAGTTTAATA
GAGAGTAACT
GAGAGTAACT
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
GCTGCATTCT
AATCATCACT
AACGTTCACT
ACTGCTATCT
ACTGCTATCT
GCTGCATGCC
GCTGCATGCC
GCTGCATGCC
GCTGCAGTGT
GCTGCAGTGT
GCTGCATGCC
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
GCTGTGTGAT
CTTTGCTACT
AACTACAGCT
AACTACAGCT
AACTACAGCT
AACTATAGCT
AACTACAGCT
GCT-CATCCC
GCT-CATCCC
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAA
GTGACGTTAG
GTGACGTTAG
GTGACGTTAC
GTGACGTTAC
TTGACGTTAG
TTGACGTTAG
TTGACGTTCG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAG
TTGACGTTAA
TTGACGTTAG
GTGACGTTAC
GTGACGTTAC
GTGACG-TAC
ATGACGTTAC
GTGACGTTAC
GTGACGTTAC
CTGACGGTAT
CTGACGGTAT
-TGACAGTAC
-TGACAGTAG
-TGACAGTAG
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
----------TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
-TGACTGTAC
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
CAACAGAAGA
TCGCAGAAGA
TCGCAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
CGACAGAAGA
TCGCAGAAGA
TCGCAGAAGA
TCGCAGAAGA
TCGCATAAGA
TCGCAGAAGA
TCGCAGAAGA
CTAACCAAAA
CTAACCAGAA
CTGGTAAAGA
CAGGTAAAGA
CCGAAGAAGA
CCCAATAAGA
CCGAATAAGA
CCGAATAAGA
CCGAATAAGA
TCGAATAAGA
---------CCGAATAAGA
CCGAATAAGA
CCGAATAAGA
CCGAATAAGA
CCGAATAAGA
CCGAATAAGA
CCCAATAAGA
CCTAAGAATA
CCTAAGAATA
CCGAAGAATA
CCGAAGAATA
CCGAAGAATA
551
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
AGCACCGGCT
G---CCGGAT
AGCCACGGCT
AGCCCCGGCT
AACCCCGGCT
AGGACCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
---------AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGYT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AGGTCCGGCT
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTCCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTACGTGC
AACTACGTGC
AACTCCGTGC
AACTCCGTGC
AATTCCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
---------AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
AACTTCGTGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
---------CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
CAGCAGCCGC
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGT
GGTAATACGT
GGTAATACGG
GGTAATACGG
GGTAATACGG
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
---------GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGTAATACGA
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCGAG
AGGGTGCAAG
GGGGTGCHAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
GGGGTGCAAG
AGGTGGCAAG
AGGTGGCAAG
AGGGGGCTAG
AGGGGGTTAG
AAGGTCCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
---------AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
AGGGACCTAG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTACATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGTTA-ATCG
CGT---GCCG
CGTTG-TCCG
CGTTG-TTCG
CGTTG-TTCG
CGTTG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
---------CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAG-TTCG
CGTAA-TTCG
CGTAG-TTCG
CGTAG-TTCG
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACTGG
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAAT--CT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GA-TTATT-G
GATTTAT--G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
---------GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GAATTACT-G
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAACAG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTA--AG
GGCGTA--AG
GGCGTAA-AG
GGCGTA--AG
GGCGTAA-AG
GGCGTA--AG
GGCGTA--AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
---------GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCTTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
GGCGTAA-AG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGTTCGTAGG
CGCGCGTA-G
CGCGCGTAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGCATGCAGG
CGTACGCAGG
CGTACGCAGG
CGTACGCAGG
CGTACGCAGG
CGTACGCAGG
CGAGCGCAGG
CGAGCGCAGG
CGTACGTAGG
CGCACGTAGG
CGCATGTAGG
AGCTCGTAGG
AGCTCGTAGG
AGCTCGTAGG
AGCACGTAGG
AGCACGTAGG
---------AGTTCGTAGG
AGTTCGTAGG
AGTTCGTAGG
AGTTCGTAGG
AGTTCGTAGG
AGTTCGTAGG
AGTTCGTAGG
CGCGCGTAGG
CGCGCGTAGG
CGCGCGTAGG
AGTATGTAGG
AGTATGTAGG
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTCTATTA
CGGTTATTTA
CGGTTATTTA
TGGTTAATTA
TGGTT--ATT
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTCTGTTA
CGGTTTGTTA
CGGTTTGTTCGGTTTGTTCGGTTTGTTA
CGGTTTGTTA
CGGTTTGTTA
CGGTTCTTTA
CGGTTCTTTA
CCGATTGGAA
CGGATTAGAA
CGGAACAAAA
TGGTTAAAAA
TGGTTAAAAA
TGGTTAGAAA
TGGTTAAAAA
TGGTTAAAAA
---------TGGTTGAAAA
TGGTTGAAAA
TGGTTGAAAA
TGGTTGAAAA
TGGTTGAAAA
TGGTTAAAAA
TGGTTAAAAA
CCGTTGAGTT
CCGTTGAGTT
CGGTTAAGTA
CGGCTAGATA
TGGTTAGATA
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGTCAGATGT
AGTCAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCGAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGCAAGATGT
AGTCTGATGT
AGTCTGATGT
AGTAGGGGGT
AGTTAGAGGT
AGTTAGAAGT
AGTTGATGGT
AGTTGATGGT
AGTTGGTGGT
AGTTGGTGGT
AGTTGGTGGT
---------AGTTGGTGGT
AGTTAGTGGT
AGTTGGTGGT
AGTTGGTGGT
AGTTGGTGGT
AGTTGGTGGT
AGTTGGTGGT
AGTTAATTGT
AGTTAATTGT
AGTTAATTGT
AGTTAATTGT
AGTTAATTGT
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
661
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCAAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCAG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCGG
GAAAGCCCCG
GAAAGCCCCG
GAAAGCCCCG
GAAAGCCCCG
GAAAGCCCCG
GAAAGCCCCG
GAAAGCCCCC
GAAAGCCCCC
GAAATCCCAG
GAAATCCCGG
GAAATCCCTG
GAAATCCCAA
GAAATCCCAA
GAAATCCCAA
GAAATCCCAG
GAAATCCCAG
---------GAAATCCCAG
GAAATCCCAG
GAAATCCCAG
GAAATCCCAG
GAAATCCCAG
GAAATCCCAG
GAAATCCCAG
GAAATCCCAA
GAAATCCCAA
GAAAGCCCAA
GAAAGCCCAA
GAAAGCCCAA
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
-GCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTCAACCG
GGCTCAACCG
GGCTTAACCC
GGCTCAACCC
GGCTCAACCT
GGCTCAACCT
GGCTCAACCT
GGCTTAACCT
AGCTTAACTC
AGCTTAACTC
---------AGCTTAACTC
AGCTTAACTC
AGCTTAACTC
AGCTTAACTC
AGCTTAACTC
AGCTTAACTC
AGCTTAACTC
AGCTTAACTT
AGCTTAACTT
AGCTCAACTT
AGCTTAACTT
AGCTTAACTT
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
TGGAACTGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
CGGAACCGCA
GGGAACTGCA
GGGAATTGCA
GGGAATTGCA
GGGAATTGCA
GGGAATTGCA
GGGAATTGCA
GGGAGGGTCA
GGGAGGGTCA
TGGAACTGCC
CGGAACTGCC
AGGAATTGCT
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
---------TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCC
TGGAACTGCA
TGGAACTGCA
TGGAATTGCA
TGGAACTGCA
TGGAATTGCA
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTGAAACTG
TTTGAAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTCGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTTTGAACTG
TTGGAAACTG
TTGGAAACTG
TCCTAAACTA
TTTAAAACTA
TTTAAAACTT
ATCAAAACTG
ATCAAAACTT
GCCAAAACTT
ATCAAAACTT
ATCAAAACTT
---------ATCAAAACTT
ATTAAAACTT
ATCAAAACTT
ATCAAAACTT
ATCAAAACTT
ATCAAAACTT
ATCAAAACTT
ATTAAAACTG
ATTAAAACTG
ATTAAAACTA
ATTAAAACTA
ATTAAAACTA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GTAGACTAGA
GGTAACTAGA
GGTAACTAGA
GTTGACTAGA
GTTGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAGACTAGA
GCAAACTAGA
GCAAACTAGA
GCAAACTAGA
GCAAACTAGA
GCAAACTAGA
GCAAACTAGA
GAGAACTTGA
GAGAACTTGA
ACAGTCTAGA
CTAGTCTAGA
TTGTTCTGGA
TTTAGCTAGA
TTTAGCTAGA
TTTGACTAGA
TTTAGCTAGA
TTTAGCTAGA
---------TTCAGCTGGA
TTCAGCTAGA
TTCAGCTAGA
TTCAGCTAGA
TTCAGCTAGA
TTTAGCTAGA
TTTAGCTAGA
CTCGACTAGA
CTCGACTAGA
TTTAGCTAGA
TTTAGCTAGA
TTTAGCTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTAGA
GTACTGTA-A
GTACTGTA-A
GT-TTGTAGA
GTTTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTTCTTGAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTCTTGTAGA
GTGCAGAAGA
GTGCAGAAGA
GTTCGAGAGA
GTTCGAGAGA
ATTCAGGAGA
GTGTGATAGA
GTGTGATAGA
GTATGATAGA
GTATGATAGA
GTGTGATAGA
--------GA
GTTTGATAGA
GTATGATAGA
GTATGATAGA
GTATGATAGA
GTATGATAGA
GTATGATAGA
GTATGATAGA
GTTTGATAGA
GTTTGATAGA
GTTTATCAGA
GTATGATAGA
GTATGATAGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTGGA
GGGTGGTAGA
GGGTGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGTGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGGGGGTAGA
GGAGAGTGGA
GGAGAGTGGA
GGTGAGTGGA
GGTGAGTGGA
GGAAAATGGA
GGAAAGTGGA
GGTAAGCGGA
GGAAAGTGGA
GGAAAGTAGA
GGAAAGTAGA
GGAAAGTAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCAGA
GGAAAGCGGA
GGAAAGCGGA
GGAAAGCGGA
GGAAAGCGGA
GGAAAGCGGA
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
ATTTCCAGTG
AT-TCCAGTG
ATTTCCAGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTTCAGGTG
ATTCCACGTG
ATTCCACGTG
ATTCCAAGTG
ATTCCGAGTG
ATTTCCAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATTTCTAGTG
ATACATAGTG
ATACATAGTG
ATACATAGTG
ATACATAGTG
ATACATAGTG
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGCGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAKAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
TAGAGGTGAA
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAG
ATGCGTAGAT
ATGCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTCGTAGAT
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAAGGA
ATTGGAWGGA
ATTGGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATCTGAAGGA
ATGTGGAGGA
ATGTGGAGGA
ATTTGGAGGA
ATTCGGAGGA
ATTGGAAGGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTAGAAAGA
ATTATGTAGA
ATTATGTAGA
ATTATGTAGA
ATTATGTAGA
ATTATGTAGA
771
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
ACATCAGTGG
NCATCAGTGG
ACATCAGTGG
ATACCAGTGG
ATACCAGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCAGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ATACCGGTGG
ACACCAGTGG
ACACCAGTGG
ACACCAGTGG
ACACCAGTGG
ACACCAGTGG
ACACCAAAAG
ACACCAAATG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
ATACCAATTG
GTACCAATTG
ACACCAGTTG
ACACCAGTTG
ACACCAGTTG
ACACCAGTTG
ACACCAGTTG
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAA-GCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAA-GCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGAC
CGAAGGCGAC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGAT
CGAAGGCAAC
CGAAGGCAAC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCAGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CGAAGGCGGC
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CACCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CACCTGGCAA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
CCCCTGGACA
TCTCTGGTCT
TCTCTGGTCT
TCACTGGCTC
TCACTGGCTC
TTTCTGGACT
TTTCTGGATC
TTACTGGGTC
TTTCTGGATC
TTTCTGGATC
TTTCTAGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGATC
TTTCTGGGAT
TTTCTGGATC
TTTCTGGATC
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
GATACTGACG
AAGACTGACA
AAGACTGACA
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
GTAACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
AAGACTGACG
GTAACTGACG
GTAACTGACG
GATACTGACG
GATACTGACG
GATATTGACG
ACTACTGACA
ACTACTGACA
ATTACTGACA
ATTACTGACA
ATTACTGACA
ATTACTGACA
AATACTGACA
ATTACTGACA
ATTACTGACA
ATTACTGACA
ATTACTGACA
ATTACTGACG
ATNACTGACG
AACACTGACG
AACACTGACG
AACACTGACG
ATTACTGACG
ATTACTGACG
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CTGGAGGAAC
CT-GAGGCGC
CT-GAGGCGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-CAGATGC
CT-GAGGTAC
CT-GAGGTAC
CT-GAGGTAC
CT-GAGGTAC
CT-GAGGTAC
CT-GAGGCTC
CT-GAGGCTC
CT-GAGGTAC
CT-GAGGTGC
CT-GAGATGC
CT-GAGGAGC
CT-GAGGAGC
CT-GAGGAGC
CT-GAGGTGC
CT-GAGGTGC
CT-GAGGTGC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGAAC
CT-GAGGCGC
CT-GAGGCGC
CT-GAGGTGC
CT-GAGATAC
CT-GAGATAC
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAAGGCG-T
GAAG-GCG-T
GAAG-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCGCT
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GCG-T
GAAA-GTG-T
GAAG-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GCA-T
GAAA-GTA-T
GAAA-GTA-T
GAAA-GTA-T
GAAA-GTA-T
GAAA-GTA-T
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCGAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGTAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGGAGCAAA
GGGTAGCAAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCAAA
GGGTAGCAAA
GGGTAGCGAA
GGGTAGCGAA
GGGTAGCGAA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CGGGATTAGA
CGGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CGGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CAGGA-TAGA
CAGGATTAGA
CAGGATTAGA
CAGGATTAGA
CGGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
GAGGATTAGA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCCGGTA
TACCCCGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCCGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCTGGTA
TACCCCGGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
TACCCTCGTA
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCACGGC
GGTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-GC
-GTCCAC-AC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-GC
-GTCCAT-AC
-GTCCAT-AC
-GTCCAT-AC
-GTCCAT-AC
-GTCCAT-AC
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
AGTAAACGAT
AGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGT-AACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
AGTAAACGAT
TGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CGTAAACGAT
CATAAACGAT
CATAAACGAT
CGTAAACGAT
CATAAACGAT
TGTAAACGAT
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
881
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
-GTCAACTAG
GGTCAACTAG
-GTCTATTAG
-GTCTATTAG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTTG
-GTCTACTCG
-GTCTACTCG
-GTCTACTCG
-GTCTACTCG
-GTCTACTCG
-GTCTACTCG
-GAGTGCTAA
-GAGTGCTAA
-GAATGCCAG
-GAATGCCAG
-GGGTGCTAG
-GTGTGCTAG
-GTGTGCTAG
-GTGTGCTAG
-GTGTGCTAG
-GTGTGCTAG
-GTGTGCTAG
-GTGTGTTAG
-GTGTGTTAG
-GTGTGTTAG
-GTGTGTTAG
-GTGTGTTAG
-GTGTGTTAG
-GTGTGTTAG
-GATTGCTAG
-GATTGCTAA
-GATTGTTAG
-GATTATTAA
-GATTATTAG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTTGTGG
CCGTTCGTGG
CCGTTCGTGG
AAGTTTGTGG
AAGTTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
AAGGTTGTGG
GAGTTTGGTT
GAATTTGGTG
GAATTTGGTG
GAATTTGGTG
GAATTTGGTG
GAATTTGGTG
GTGTTGGAGG
GTGTTGGAGG
TCGTTGGATA
TCGTCGGGTA
TCGTC---GG
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ACGTTGGAAA
ATGTTGGAAA
GATGTTGGAA
ATGTTGGAAA
ATG--TGGGG
ATG--TGGGG
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
ACTTGA-TCC
CTATAT-GCC
CTATA--TCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCCTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GCC
CCTTGA-GAA
TCTTGA-ACA
TCTTGA-ACA
TCTTGA-ACA
TCTTGA-ACA
TCTTGA-ACA
GTTTCC-GCC
GTTTCCGCCC
GCATG--CTA
GTATA--CTA
ACTT---TTG
TTTA---TCT
TATA---TTT
TTTA---ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
TTT----ATT
ATTTA--TTT
TTT----ATT
AATTA--TTT
AATTA--TTT
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGAGTGGCG
GTGGGTTTCA
GTGGGTTTCA
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
GTGGCTTTCG
CTGGGCTCTT
CTGGGTTCCC
CTGGGTTCCC
CTGGGTTCCC
CTGGGTTCCC
CTGGGTTCCC
TTCAGTGCTG
TTCAGTGCTG
TTCAGTGACA
TTCGGTGACA
TTCGGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTGTCG
TTCAGTATCG
TCAAGTATCG
TTCAGTATCA
CTCTGTATTA
CTCTGTATCA
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
AAGCTAACGC
AAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
GAGCTAACGC
AAGCTAACGC
AAGCTAACGC
AAGCTAACGC
AAGCTAACGC
AAGCTAACGC
AAGCTAACGC
CAGCTAACGC
CAGCTAACGC
CACCTAACGG
CACCTAACGG
TAGCTAACGC
CAGCAAAAGC
CAGCGAAAGC
CAGCAAAAGC
CAGCGAAAGC
CAGCAAAAGC
CAGCAAAAGC
CAGCGAAAGC
CAGGGAAACC
CAGGGAAACC
CAGGGAAACC
CAGGGAAACC
CAGCGAA-AN
CAGCGAAAGC
CAGCTAACGC
CAGCTAACGC
CAGCTAACGC
TAGCTAACGC
CAGCTAACGC
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGTTGA
ACTAAGT-GA
ATTAAATAGA
ATTAAATAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
GTTAAGTAGA
ATTAAGTAGA
ATTAAGTAGA
ATTAAGTAGA
ATTAAGTAGA
ATTAAGTAGA
ATTAAGTAGA
ATTAAGCACT
ATTAAGCACT
ATTAAGCATT
ATTAAGCATT
GTTAAGCACC
GTTAAGCACA
ATTAAGCACA
GTTAAGCACA
GTTAAGCACA
ATTAAGCACA
GTTAAGCACA
GATAAACACA
GATAAACACA
GATAAACACA
GATAAACACA
GATAAACACA
ATTAAACACA
ATTAAACACA
ATTAAGCAAT
ATTAAGCAAA
GTTAAACAAT
GTTAAATAAT
GTTAAATAAT
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
TCCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
-CCGCCTGGG
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGGCC
GAGTACGACC
GAGTACGACC
GAGTACGGTC
GAGTACGGTC
GAGTACGGTC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GAGTACGACC
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTGA
GCAAGGTTGA
GCAAGATTAA
GCAAGATTAA
GCAAGATTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAG-TTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
GCAAGGTTAA
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAAGG
AACTCAAAGG
AACTCAAAGG
AACTCAAAGG
AACTCAAATA
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AACTCAAATG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
AATTGACGGG
991
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GG-CCCGCAC
GG-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
GGACCCGCAC
GA-CCCGCAC
GA-CCCSCAC
GA-CCCGCAC
GA-CCCGCAC
GA-CCCGCAC
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGCAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGTAGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
AAGCGGTGGA
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGCT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
GCATGTGGTT
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGATG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGACG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
TAATTCGAAG
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-AA
CAACGCG-CA
CAACGCG-CA
CAACGCG-AA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCG-CA
ATACGCGCCA
CTACGCG-CA
CAACGCG-CA
CAACGCG-CA
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTT--GAACCTTACC
GGACCTTACC
KAACCTTACC
GAACCTTACC
GAACCTTACC
GAACCTTACC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
ATCCCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
TACTCTTGAC
AGGTCTTGAC
AGGTCTTGAC
AACCCTTGAC
AACCCTTGAC
AGCGTTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
AACACTTGAC
--CACTTGAC
AACACTTGAC
AACCCTTGAC
AACCCTTGAC
AACACTTGAC
AACCCTTGAC
AACCCTTGAC
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCTCA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCAGA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCACA
A---TCCTTT
A---TCCTTT
ATA-CTTGTC
A---TCCTGT
A---TGGGAA
ATG-TTCGTC
ATG-TTCGTC
ATGTTTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TTCGTC
ATG-TCTGTC
ATG-TCTGTC
ATG-TCTGTC
ATG-TTTGTC
ATG-TTCGTC
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGAGACTA
GAAGCCAGTA
GAAGAGACTA
GAATCACCTA
GAATCACCTA
GAAGTTACCA
GAAGTTACCA
GAAGTTACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAAGAGACCA
GAATCTGGTA
GAATTCGCTA
GAATTCGCTA
GAATTTGCTA
GAATTCGCTA
GAATTCGCTA
GACAATCCTA
GACAATCCTA
GCGGTGACCA
GCTACATTCA
GTGCCGGTTA
GCGAGACCAA
GCGAGCCTAA
GCGACTTCAA
GCGACTTTAA
GCGACTTTAA
GCGACTTTAA
GCGACTTTAA
GCGACTCTAA
GCGACTCTAA
GCGACTCTAA
GCGACTCTAA
GCGACTCTAA
GCGACTCTAA
GCGAGTTTAG
GCGAGTTTAG
GCGGATTCCA
GCGAAACTAA
GCGAGACTAA
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TAGAC
GAGA-TACAS
GAGA-TAGAC
GAGA-TAGAT
GAGA-TAGAT
GAGA-TGGTT
GAGA-TGGTT
GAGA-TGGTT
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TGGAC
GAGA-TACCT
GAGA-TAGCT
GAGA-TAGCT
GAGA-TAGCT
GAGA-TAGCT
GAGA-TAGCT
GAGA-TAGGA
GAGA-TAGGA
GAGA-TGGAC
GAGA-TGAAT
CAGAATGGTA
GAGA-GTGGT
GAGATTAGGC
GAGATTGAAGAGATTAAAGAGATTGAAGAGATTAAAGAGATTAAAG
GAGATTAGAG
GAGATTAGAG
GAGATTAGAG
GAGATTAGAGAGATTAGAGAGATTAGAGAAACTAGAC
GAAACTAGAC
GAGA-TGGAT
GAGATTAGTT
GAAATTAGTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
GCGTGCCTTC
TTGTGCCTTC
GAGTGCCTTC
GAGTGCCTTC
TCGTGCCTTC
TCGTGCCTTC
TCGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
TTGTGCCTTC
CAGTGCCTTC
TAGTGCCTTC
TAGTGCCTTC
TAGTGCCTTC
TAGTGCCTTC
TAGTGCCTTC
CTTTCCCTTC
CTTTCCCTTC
----ACCTTC
GGTTCCTTTC
----ATCTTC
TTCTTCATTT
TTTTCAGTTC
----GTCTTC
----GTCTTC
----GTCTTC
----GTCTTC
TTTTCGGTTC
TTTTCGGTTC
TTTTCGGTTC
TTTTCGGTTC
----GTTTTC
----GTTTTC
----GTTTTC
TTTTCGGTTC
TTTTCGGTTC
T----CCTTC
TCTTCAGTTC
T-----CTTC
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
640698396_C_psychrerythraea_34H
640698404_C_psychrerythraea_34H
640698412_C_psychrerythraea_34H
640698493_C_psychrerythraea_34H
640698426_C_psychrerythraea_34H
640698400_C_psychrerythraea_34H
640698408_C_psychrerythraea_34H
640698416_C_psychrerythraea_34H
640698390_C_psychrerythraea_34H
DQ027051.1_Colwellia_sp_MT41
DQ027052.1_Colwellia_sp_KT27
DQ027056.1_Psychromonas_sp_CNPT3
DQ027057.1_Psychromonas_sp_HS11
640705772_P_profundum_SS9
DQ027054.1_P_profundum_3TCK
DQ027055.1_P_profundum_1230sf1
640705946_P_profundum_SS9
640705754_P_profundum_SS9
640705856_P_profundum_SS9
640705924_P_profundum_SS9
640705919_P_profundum_SS9
640705763_P_profundum_SS9
640705741_P_profundum_SS9
640705850_P_profundum_SS9
640705738_P_profundum_SS9
640705907_P_profundum_SS9
640705913_P_profundum_SS9
640705910_P_profundum_SS9
640705881_P_profundum_SS9
640705884_P_profundum_SS9
DQ027053.1_Moritella_sp_PE36
DQ027059.1_Shewanella_sp_PT48
DQ027060.1_Shewanella_sp_PT64
641466167_P_profundum_SS9
DQ027058.1_Shewanella_sp_KT99
641463346_P_profundum_SS9
DQ027061.1_Carnobacterium_sp_AT7
DQ027062.1_Carnobacterium_sp_AT12
JF303756.1_Rhodobacterales_PRT1
639101207_P_profundum_3TCK
2504111167_HIMB59b
U75256.1_SAR211g2
AF353214.1_Arctic95B-1g2
2236674967_AAA288-E13
2236446051_AAA288-G21
2236452142_AAA288-N07
2236674298_AAA240-E13
2504109332_HIMB5b
2503352260_HTCC7211
2503364240_HTCC9565
640708248_HTCC1062
642513240_HTCC1002
X52172.1_SAR11g1b
U75649.1_SAR193g1b
Z99997.1_LD12
AB154304.1_S9D-28fresh
2503356127_HIMB114
2505687060_IMCC9063
U70686.1_OM155g3
1101
640698396_C_psychrerythraea_34H
GG-------G
640698404_C_psychrerythraea_34H
GG-------G
640698412_C_psychrerythraea_34H
GG-------G
640698493_C_psychrerythraea_34H
GG-------G
640698426_C_psychrerythraea_34H
GG-------G
640698400_C_psychrerythraea_34H
GG-------G
640698408_C_psychrerythraea_34H
GG-------G
640698416_C_psychrerythraea_34H
GG-------G
640698390_C_psychrerythraea_34H
GG-------G
DQ027051.1_Colwellia_sp_MT41
GG-------G
DQ027052.1_Colwellia_sp_KT27
GG-------G
DQ027056.1_Psychromonas_sp_CNPT3
GG-------G
DQ027057.1_Psychromonas_sp_HS11
GG-------G
640705772_P_profundum_SS9
GG-------G
DQ027054.1_P_profundum_3TCK
GG-------G
DQ027055.1_P_profundum_1230sf1
GG-------G
640705946_P_profundum_SS9
GG-------G
640705754_P_profundum_SS9
GG-------G
640705856_P_profundum_SS9
GG-------G
640705924_P_profundum_SS9
GG-------G
640705919_P_profundum_SS9
GG-------G
640705763_P_profundum_SS9
GG-------G
640705741_P_profundum_SS9
GG-------G
640705850_P_profundum_SS9
GG-------G
640705738_P_profundum_SS9
GG-------G
640705907_P_profundum_SS9
GG-------G
640705913_P_profundum_SS9
GG-------G
640705910_P_profundum_SS9
GG-------G
640705881_P_profundum_SS9
GG-------G
640705884_P_profundum_SS9
GG-------G
DQ027053.1_Moritella_sp_PE36
GG-------G
DQ027059.1_Shewanella_sp_PT48
GG-------G
DQ027060.1_Shewanella_sp_PT64
GG-------G
641466167_P_profundum_SS9
GG-------G
DQ027058.1_Shewanella_sp_KT99
GG-------G
641463346_P_profundum_SS9
GG-------G
DQ027061.1_Carnobacterium_sp_AT7
GG-------G
DQ027062.1_Carnobacterium_sp_AT12 GG-------G
JF303756.1_Rhodobacterales_PRT1
AGCTAGGCTG
639101207_P_profundum_3TCK
GG-------G
2504111167_HIMB59b
AGTTCGGCTG
U75256.1_SAR211g2
AGTTGGGCGA
AF353214.1_Arctic95B-1g2
GGCTGGACGA
2236674967_AAA288-E13
AGTTTGGCTG
2236446051_AAA288-G21
GGTTCGGCCG
2236452142_AAA288-N07
GGTTCGGCCG
2236674298_AAA240-E13
GGTTCGGCCG
2504109332_HIMB5b
GGCCGGACGA
2503352260_HTCC7211
GGCCGGACGA
2503364240_HTCC9565
GGCCGGACGA
640708248_HTCC1062
GGCCGGACGA
642513240_HTCC1002
GGTTTGGCCG
X52172.1_SAR11g1b
GGTTCGGCCG
U75649.1_SAR193g1b
GGTTCGGCCG
Z99997.1_LD12
GGCCGGACAG
AB154304.1_S9D-28fresh
GGCCGGACAG
2503356127_HIMB114
GGTTCGGCCG
2505687060_IMCC9063
GGCTGGACAA
U70686.1_OM155g3
GGTTCGGCCG
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTCTGTGA
AACTGAGTGA
AACTCTGTGA
AACTCTGAGA
AACTCTGAGA
AACTGTGAGA
AACTCTGAGA
AACTCTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
AACTGTGAGA
GACAAAGTGA
GACAAAGTGA
GACG-AGATA
GACGCAGTGA
GCTTCCGC-A
AAC------A
AAC------A
GACG-AAACA
GACG-AAACA
GACG-AAACA
GACG-AAACA
AAC------A
AAC------A
AAC------A
AAC------A
GACG-AAACA
GACG-AAACA
GACG-AAACA
AAC------A
AAC------A
GACA-GAACA
AAC------A
GACG-AAACA
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGATGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGGTGC
CAGGTGGTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
CAGGTGCTGC
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGTTGTCG
ATGGTTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
ATGGCTGTCG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TCAGCTCGTG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
CTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TTGTGAAATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TCGTGAGATG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTCGGTTAAG
TTCGGTTAAG
TTGGGTTAAG
TTGGGGTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TTGGGTTAAG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAGCG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCGGCAACG
TCCGGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCACAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
TCCCGCAACG
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCA
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCACAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
AGCGCAACCC
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
CTATCCTTAT
TTATCCTTAC
TTATCCTTAC
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTGT
TTATCCTTAT
TTATCCTTAT
TTATCCTTAT
TTATCCTTAT
TTATCCTTAT
TTATCCTTAT
CTATTATTAG
CTATTATTAG
ACGTCCTTAG
ACATCCCTAG
TTATCGTTAG
CTACGTTTAG
CTACTTTTAG
TTACTTTTAG
TTACTTTTAG
TTACTTTCAG
TTACTTTTAG
TCACTTTTAG
TCACTTTTAG
TCACTTTTAG
TCACTTTTAG
TCACTTTTAG
TCACTTTTAG
TCACTTTTAG
CTACTTTTAG
CTACTTTTAG
CTACTTCTAG
CTACTTTTAG
CTACTTTTAG
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGC
TTGCCAGCGG
TTGCCAGCGG
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCAC
TTGCCAGCATTGCCAGCATTGCCAGCAG
TTGCCAGCATTACTAACATTACTAACATTGCCACCATTGACACCATTGCCATCATTGCCACCATTGCCATCATTGCCATCATTGCCATCATTGCCATCATTGCCATCATTGCCATCATTGCCATCATTGCCATCATTGCCATCAG
TTGCCATCAG
TTGCCATCAG
TTGCCATCAG
TTGCCATCAG
1211
640698396_C_psychrerythraea_34H
GTTATG-GCG
640698404_C_psychrerythraea_34H
GTTATG-GCG
640698412_C_psychrerythraea_34H
GTTATG-GCG
640698493_C_psychrerythraea_34H
GTTATG-GCG
640698426_C_psychrerythraea_34H
GTTATG-GCG
640698400_C_psychrerythraea_34H
GTTATG-GCG
640698408_C_psychrerythraea_34H
GTTATG-GCG
640698416_C_psychrerythraea_34H
GTTATG-GCG
640698390_C_psychrerythraea_34H
GTTATG-GCG
DQ027051.1_Colwellia_sp_MT41
GTTATG-GCG
DQ027052.1_Colwellia_sp_KT27
GTTATG-GCG
DQ027056.1_Psychromonas_sp_CNPT3
GTCATG-CCG
DQ027057.1_Psychromonas_sp_HS11
GTCATG-CCG
640705772_P_profundum_SS9
GTCATG-GTG
DQ027054.1_P_profundum_3TCK
GTAATG-GTG
DQ027055.1_P_profundum_1230sf1
GTAATG-GTG
640705946_P_profundum_SS9
GTAATG-GTG
640705754_P_profundum_SS9
GTCATG-GTG
640705856_P_profundum_SS9
GTAATG-GTG
640705924_P_profundum_SS9
GTCATGAGTG
640705919_P_profundum_SS9
GTCATG-GTG
640705763_P_profundum_SS9
GTCATG-GTG
640705741_P_profundum_SS9
GTCATG-GTG
640705850_P_profundum_SS9
GTCATG-GTG
640705738_P_profundum_SS9
GTCATG-GTG
640705907_P_profundum_SS9
GTCATG-GTG
640705913_P_profundum_SS9
GTCATG-GTG
640705910_P_profundum_SS9
GTCATG-GTG
640705881_P_profundum_SS9
GTCATG-GTG
640705884_P_profundum_SS9
GTCATG-GTG
DQ027053.1_Moritella_sp_PE36
GTAATG-GTG
DQ027059.1_Shewanella_sp_PT48
GTAATG-GTG
DQ027060.1_Shewanella_sp_PT64
GTAATG-GTG
641466167_P_profundum_SS9
GTAATG-GTG
DQ027058.1_Shewanella_sp_KT99
GTAATG-GTG
641463346_P_profundum_SS9
GTAATG-GTG
DQ027061.1_Carnobacterium_sp_AT7
-TTCAG-TTG
DQ027062.1_Carnobacterium_sp_AT12 -TTCAG-TTG
JF303756.1_Rhodobacterales_PRT1
GTTAAG-CTG
639101207_P_profundum_3TCK
GTTCGG-CTG
2504111167_HIMB59b
GTTCGG-CTG
U75256.1_SAR211g2
-TTTAG-TTG
AF353214.1_Arctic95B-1g2
-TTTAG-TTG
2236674967_AAA288-E13
-TTTAG-TTG
2236446051_AAA288-G21
-TTTAG-TTG
2236452142_AAA288-N07
-TTTAG-TTG
2236674298_AAA240-E13
-TTTAG-TTG
2504109332_HIMB5b
-TTAAG-TTG
2503352260_HTCC7211
-TTAAG-TTG
2503364240_HTCC9565
-TTAAG-TTG
640708248_HTCC1062
-TTAAG-TTG
642513240_HTCC1002
-TTAAG-TTG
X52172.1_SAR11g1b
-TTTAG-TTG
U75649.1_SAR193g1b
-TTCAG-TTG
Z99997.1_LD12
GTCATG-CTG
AB154304.1_S9D-28fresh
GTCATG-CTG
2503356127_HIMB114
GTTAAG-CTG
2505687060_IMCC9063
GTTATG-CTG
U70686.1_OM155g3
GTTAAG-CTG
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTCT-A
GGAACTTT-A
GGAACTTT-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCC-A
GGAACTCT-A
GGAACTTT-A
GGAACTTT-A
GGAACTTT-A
GGAACTTT-A
GGAACTTT-A
GGCACTCT-A
GGCACTCT-A
GGCACTCT-A
GGCACTCT-A
AGGACTCT-A
AGCACTCT-A
GGCACTTT-A
AGCACTCT-G
GGCACTCT-G
AGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCT-G
GGCACTCTGA
GGCACTCT-G
GGCACTCT-G
GGCACTCT-A
GGCACTCT-A
GGCACTCT-A
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
AGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACGGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
AGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GGGAGACTGC
GTGAGACTGC
GTGAGACTGC
GGGAGACTGC
TGGAAACTGC
GCGAAACTGC
AGAAGACTCC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAAGAACTGC
AAGTAACTGC
AAAGAACTGC
AAAGAACTGC
GTAGGACTGC
ATAGAACTGC
ATAGAACTGC
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
TGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAA
CGGTGATAAG
CCGTGATAAG
CGGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CAGTGATAAG
CTGTGATAAG
CTGTGATAAA
CTGTGATAAA
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CCGGAGGAAG
CGGGAGGAAG
CCGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CTGGAGGAAG
CAGGAGGAAG
CAGGAGGAAG
CAGGAGGAAG
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGTCGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGACGA
GTGGGGATGA
GTGGGGATGA
GTGTGGATGA
GTGTGGATGA
GTGGGGATGA
NCGGGGATGA
GTGGGGATGA
GTGGGGATTA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGGGGATGA
GTGTGGCTGG
GCGAGGATGA
GTGGGGATGA
GTGGGGATGA
GTTGGGATGA
GTGGGGATGA
GTGGGGATGA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGATA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAGTCA
CGTCAAATCA
CGTCAAATCA
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
---------CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
CGTCAAGTCC
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATCGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGCCCCT
TCATGCCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
---------TCATGGCCCT
TCATGGGCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TCATGGCCCT
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGGGATGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TACGAGTAGG
TATGACCTGG
TATGACCTGG
TACGGGTTGG
TACGGGTTGG
TACACGCTGG
TACGTGTTGG
TATGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
TACGTGTTGG
---------TACGTGTTGG
TACGGGTTGG
TACGGGTTGG
TACGTGTTGG
TACGGGTTGG
TACGGGTTGG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
---------GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
GCTACACACG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
---------TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
TGCTACAATG
1321
640698396_C_psychrerythraea_34H
GCAGGTACAG
640698404_C_psychrerythraea_34H
GCAGGTACAG
640698412_C_psychrerythraea_34H
GCAGGTACAG
640698493_C_psychrerythraea_34H
GCAGGTACAG
640698426_C_psychrerythraea_34H
GCAGGTACAG
640698400_C_psychrerythraea_34H
GCAGGTACAG
640698408_C_psychrerythraea_34H
GCAGGTACAG
640698416_C_psychrerythraea_34H
GCAGGTACAG
640698390_C_psychrerythraea_34H
GCAGGTACAG
DQ027051.1_Colwellia_sp_MT41
GCAGGTACAG
DQ027052.1_Colwellia_sp_KT27
GCAAGTACAG
DQ027056.1_Psychromonas_sp_CNPT3
GCAGATACAA
DQ027057.1_Psychromonas_sp_HS11
GCAGATACAA
640705772_P_profundum_SS9
GCGTATACAG
DQ027054.1_P_profundum_3TCK
GCGTATACAG
DQ027055.1_P_profundum_1230sf1
GCGTATACAG
640705946_P_profundum_SS9
GCGTATACAG
640705754_P_profundum_SS9
GCGTATACAG
640705856_P_profundum_SS9
GCGTATACAG
640705924_P_profundum_SS9
GCGTATACAG
640705919_P_profundum_SS9
GCGTATACAG
640705763_P_profundum_SS9
GCGTATACAG
640705741_P_profundum_SS9
GCGTATACAG
640705850_P_profundum_SS9
GCGTATACAG
640705738_P_profundum_SS9
GCGTATACAG
640705907_P_profundum_SS9
GCGTATACAG
640705913_P_profundum_SS9
GCGTATACAG
640705910_P_profundum_SS9
GCGTATACAG
640705881_P_profundum_SS9
GCGTATACAG
640705884_P_profundum_SS9
GCGTATACAG
DQ027053.1_Moritella_sp_PE36
GCGCATACAA
DQ027059.1_Shewanella_sp_PT48
GTCGGTACAG
DQ027060.1_Shewanella_sp_PT64
GTCGGTACAG
641466167_P_profundum_SS9
GTCGGTACAG
DQ027058.1_Shewanella_sp_KT99
GTCGGTACAG
641463346_P_profundum_SS9
GTCGGTACAG
DQ027061.1_Carnobacterium_sp_AT7
GATGGTACAA
DQ027062.1_Carnobacterium_sp_AT12 GATGGTACAA
JF303756.1_Rhodobacterales_PRT1
GCAGTGACAG
639101207_P_profundum_3TCK
GCATCTACAG
2504111167_HIMB59b
GTAACTACAA
U75256.1_SAR211g2
GCATTTACAA
AF353214.1_Arctic95B-1g2
GTACTTACAA
2236674967_AAA288-E13
GCACTCACAA
2236446051_AAA288-G21
GCATTTACAA
2236452142_AAA288-N07
GCACTCACAA
2236674298_AAA240-E13
GCACTCACAA
2504109332_HIMB5b
GTATCTACAA
2503352260_HTCC7211
GTATCTACAA
2503364240_HTCC9565
GCATCTACAA
640708248_HTCC1062
GCATCTACAA
642513240_HTCC1002
GCATCTACAA
X52172.1_SAR11g1b
---------U75649.1_SAR193g1b
GCATTTACAA
Z99997.1_LD12
GTAGTGACAA
AB154304.1_S9D-28fresh
GTAGTGACAA
2503356127_HIMB114
GCAGTGACAA
2505687060_IMCC9063
GTAGGTACAG
U70686.1_OM155g3
GTAAGTACAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCAGCAA
AGGGCTGCAA
AGGGCTGCAA
AGGGTTGCTA
AGGGTTGCTA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCCA
AGGGCTGCAA
AGGGTCGCAA
AGGGTCGCAA
AGGGTTGCAA
AGGGTTGCAA
AGGGTTGCAA
CGAGTCGCAA
CGAGTCGCAA
TGGGTT---TGGGTT---CGGGACGCAA
TGAGACGCAA
TGGGAAGCAA
TAGGAAGCAA
TAGGAAGCAA
TAGGAAGCGA
TGGGAAGCAA
CAGGAAGCAA
CAGGAAGCGA
CAGGAAGCAA
CAGGAAGCAA
CAGGAAGCAA
---------TAGGAAGCAA
TGAGATGCAA
TGAGATGCAA
TGAGATGCTA
TGAGATGCCG
TGAGATGCCG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
TACCGCGAGG
ACCTGCGAGG
ACCTGCGAGG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCGATG
ACCAGCAATG
CGCCGCGAGG
CGCCGCGAGG
CGCCGCGAGG
CGCCGCGAGG
CGCCGCGAGG
GGTCGCGAGG
GGTCGCGAGG
------------------TACCGCGAGG
AGAGGCAACT
AGAGGCGACT
AGATGTGAGT
GATGGCGACA
AGAGGCGACT
AGAGGTGACT
GACGGCGACG
AACTGCGAAG
AACGGCAACG
AACGGCAACG
AACGGCAACG
---------GATGGCGACA
AGTGGCGACG
GGTGGCGACG
AACGGCGACG
AGCAGCGATG
AACAGCGATG
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
TGGAGCGAAT
GTATGCGAAT
GTATGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTGAGCGAAT
GTAAGCGAAT
TCAAGCTAAT
TCAAGCTAAT
TCAAGCTAAT
TCAAGCTAAT
TCAAGCTAAT
CCAAGCTAAT
CCAAGCTAAT
-------AAT
-------AAT
TGGAGCAAAT
CTAAGCCAAT
CCTAGCCAAT
CTAAGCAAAT
TCAAGCAAAT
CTAAGCAAAT
CTAAGCAAAT
TCAAGCAAAT
TTAAGCAAAT
TTAAGCAAAT
TTAAGCAAAT
TTAAGCAAAT
---------TCAAGCAAAT
CTAAGCTAAA
CTAAGCTAAA
TTAAGCTAAA
CTTAGCTAAA
TTTAGCCAAA
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACGAAGC
CCCACAAAGC
CTCATAAAGT
CTCATAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCACAAAGT
CCCATAAAGT
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CCCACAAAGC
CTCTTAAAGC
CTCTTAAAGC
CCC-TAAAAA
CCC-CAAAAG
CCC-CAAAAG
CTCACAAA-T
CCC-TAAAAT
CCTAAAAAACCTAAAAAAA
CTTAAAAAACCTAAAAAACCT-TAAAAG
CCC-TAAAAG
CCCGAAAAGCCCGAAAAGCCCGAAAAG---------CCTAAAAAGCTCA-AAAAT
CTCA-AAAAT
CTCA-AAAAC
CTC-CAAAAC
CTCA-AAAAC
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
TTGTCGTAGT
CTGTCGTAGT
TTGTCGTAGT
CTGTCGTAGT
CTGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
ACGTCGTAGT
GCGTCGTAGT
CGGTCGTAGT
CGGTCGTAGT
CGGTCGTAGT
CGGTCGTAGT
CGGTCGTAGT
CATTCTCAGT
CATTCTCAGT
CTGTCTCAGT
ATGTCTCAGT
TTATCTCAGT
ATGCCTCAGT
GTACCTCAGT
GTGCCTCAGT
ATGCCTCAGT
GTGCCTCAGT
GTGCCTCAGT
ATACCTCAGT
ATACCTCAGT
ATGCCTCAGT
ATGCCTCAGT
ATGCCTCAGT
---------ATGCCTCAGT
CTACCTCAGT
CTACCTCAGT
CTGCCTCAGT
CTACCTCAGT
TTACCTCAGT
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATTGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATTGGG
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
CCGGATCGGA
TCGGATTGCA
TCGGATTGCA
TCGGATTGGG
TCGGATTGTC
TCGGATTGCA
TCGGATTGTA
TCGGATTGTA
TCGGATTGTA
TCGGATTGTA
TCGGATTGTA
TCGGATTGTA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
---------TCGGATTGTA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
TCGGATTGCA
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GTCTGCAACT
GGCTGCAACT
GGCTGCAACT
GTCTGCAACT
GTCTGCAACT
CTCTGCAACT
CTCTNCAACT
CTCTGTAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
---------CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CTCTGCAACT
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCATG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACCCCATG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGACTCCGTG
CGCCTGCATG
CGCCTGCATG
CGACCCCATG
CGACGGCATG
CGAGTGCATG
CGAGTACATG
CGAGTACATG
CGAGTACATG
CGAGTACATG
CGAGTACATG
CGAGTACATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
---------CGAGTACATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
CGAGTGCATG
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTTGGAAT
AAGTTGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTGGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGTCGGAAT
AAGCCGGAAT
AAGCCGGAAT
AAGTTGGAAT
AAGTCGGAAT
AAGTTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
---------AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
AAGCTGGAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TGCTAGTAAT
TACTAGTAAT
TACTAGTAAT
TACTAGTAAT
TACTAGTAAT
TACTAGTAAT
---------TACTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
CGCTAGTAAT
1431
640698396_C_psychrerythraea_34H
CGTAGATCAG
640698404_C_psychrerythraea_34H
CGTAGATCAG
640698412_C_psychrerythraea_34H
CGTAGATCAG
640698493_C_psychrerythraea_34H
CGTAGATCAG
640698426_C_psychrerythraea_34H
CGTAGATCAG
640698400_C_psychrerythraea_34H
CGTAGATCAG
640698408_C_psychrerythraea_34H
CGTAGATCAG
640698416_C_psychrerythraea_34H
CGTAGATCAG
640698390_C_psychrerythraea_34H
CGTAGATCAG
DQ027051.1_Colwellia_sp_MT41
CGTGGATCAG
DQ027052.1_Colwellia_sp_KT27
CGTGGATCAG
DQ027056.1_Psychromonas_sp_CNPT3
CGTGGATCAG
DQ027057.1_Psychromonas_sp_HS11
CGTGGATCAG
640705772_P_profundum_SS9
CGTGAATCAG
DQ027054.1_P_profundum_3TCK
CGTGAATCAG
DQ027055.1_P_profundum_1230sf1
CGTGAATCAG
640705946_P_profundum_SS9
CGTGAATCAG
640705754_P_profundum_SS9
CGTGAATCAG
640705856_P_profundum_SS9
CGTGAATCAG
640705924_P_profundum_SS9
CGTGAATCAG
640705919_P_profundum_SS9
CGTGAATCAG
640705763_P_profundum_SS9
CGTGAATCAG
640705741_P_profundum_SS9
CGTGAATCAG
640705850_P_profundum_SS9
CGTGAATCAG
640705738_P_profundum_SS9
CGTGAATCAG
640705907_P_profundum_SS9
CGTGAATCAG
640705913_P_profundum_SS9
CGTGAATCAG
640705910_P_profundum_SS9
CGTGAATCAG
640705881_P_profundum_SS9
CGTGAATCAG
640705884_P_profundum_SS9
CGTGAATCAG
DQ027053.1_Moritella_sp_PE36
CGTGAATCAG
DQ027059.1_Shewanella_sp_PT48
CGTGAATCAG
DQ027060.1_Shewanella_sp_PT64
CGTGAATCAG
641466167_P_profundum_SS9
CGTGAATCAG
DQ027058.1_Shewanella_sp_KT99
CGTGAATCAG
641463346_P_profundum_SS9
CGTGAATCAG
DQ027061.1_Carnobacterium_sp_AT7
CGCGGATCAG
DQ027062.1_Carnobacterium_sp_AT12 CGCGGATCAG
JF303756.1_Rhodobacterales_PRT1
CGCGTAACAG
639101207_P_profundum_3TCK
CGCGTAACAG
2504111167_HIMB59b
CGCGGATCAG
U75256.1_SAR211g2
CGCGGATCAG
AF353214.1_Arctic95B-1g2
CGCGGATCAG
2236674967_AAA288-E13
CGCGGATCAG
2236446051_AAA288-G21
CGCGGATCAG
2236452142_AAA288-N07
CGCGGATCAG
2236674298_AAA240-E13
CGCGGATCAG
2504109332_HIMB5b
CGTGGATCAG
2503352260_HTCC7211
CGTGGATCAG
2503364240_HTCC9565
CGTGGATCAG
640708248_HTCC1062
CGTGGATCAG
642513240_HTCC1002
CGTGGATCAG
X52172.1_SAR11g1b
---------U75649.1_SAR193g1b
CGCGGATCAG
Z99997.1_LD12
CGTAGATCAG
AB154304.1_S9D-28fresh
CGTAGATCAG
2503356127_HIMB114
CGCTCATCAG
2505687060_IMCC9063
CGTGGATCAG
U70686.1_OM155g3
CGTGGATCAG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AATGCTACGG
AACGCCACGG
AATGCCACGG
AATGCCACGG
AATGCCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
AATGTCACGG
CACGCCGCGG
CACGCCGCGG
CATGACGCGG
CATGACGCGG
CATGCCGCGG
CGCGCCGCGG
CGCGCCGCGG
CGCGCCGCGG
CGCGCCGCGG
CGCGCCGCGG
CGCGCCGCGG
CGTGCCACGG
CGTGCCACGG
CGTGCCACGG
CGTGCCACGG
CGTGCCACGG
---------CGCGCCGCGG
CGTGCTACGG
CGTGCTACGG
CGCGGAGCGG
CGTGCCACGG
CGTGC-----
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATGCGTT
TGAATGCGTT
TGAATGCGTT
TGAATGCGTT
TGAATGCGTT
---------TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
TGAATACGTT
----------
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGCCTT
CCCGGGCCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
---------CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
CCCGGGTCTT
----------
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
---------GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
GTACACACCG
----------
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCACCA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
---------CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
CCCGTCA-CA
----------
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCACGAGAGT
CCACGAGAGT
CCATGGGAGT
CCATGGGAGT
CCATGAGAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
CCATGGGAGT
---------CCATGGGAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAGT
CCATGGAAAT
----------
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGATGCAAA
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
GGGCTGCACC
TTGTAACACC
TTGTAACACC
TGGGTCTACC
TGGTTCTACC
TGGTTTTATC
TGGTTACACC
TGGTTACACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
---------TGGTTCTACC
TGGTTCTACC
TGGTTCTACC
TGGTTTTACC
TGGATTTACC
----------
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTGGC
-AGAAGTCAT
-AGAAGTCAT
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTCAT
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-AGAAGTAGA
-CGAAGTCGG
-CGAAGTCGG
-CGAAGGCAG
-CGACGGCCG
-TTAAGTCAG
-TGAAGGCAA
-TTAAGGCAA
-TTAAG----TTAAG----TTAAG-------------TTAAG----TTAAGGCAA
-TTAAGGCAA
-TTAAGGCAA
-TTAAGGCAA
----------TTAAGGCAA
TTAAAGCAGA
TTAAAGCAGA
-TTAAGGCAT
TTAAGGCAAA
----------
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGTTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TAGCTTAA-TAGCTTAACC
TAGCTTAACC
TAGCTTAACC
TGAGGTAACC
TGAGGTAACC
TGCGCCAACC
TGCGCTAACTGC------AACATAAAAC
-AGCTTATAC
---------------------------------------------GGTTTTAAAC
GGTTTTAAAC
GGTTTTAAAC
GGTTTTAAAC
---------GGTTTAAAAC
TTGCT-AACC
TTGCTAACCGTCACTAACC
T------------------
CC-------CC-------CC-------CC-------CT-------CC-------CC-------CC-------CT-------TT-------TT-------TT-------TT-------CCGATCTTTT
TT-------TT-------TT-------TT-------CCGATCTTTT
TT-------TT-------CCGATCTTTT
CCGATTTTTT
TT-------TT-------TT-------TT-------TT-------TT-------TT-------TT-------CT----------------CT-------CT-------CT-------CT-------CT-------TC-------------------------TT-------CT----------------------------------------------------CC-------CC-------CC-------CC----------------CC-------GC----------------CT--------------------------
1541
640698396_C_psychrerythraea_34H
------TCGG
640698404_C_psychrerythraea_34H
------TCGG
640698412_C_psychrerythraea_34H
------TCGG
640698493_C_psychrerythraea_34H
------TCGG
640698426_C_psychrerythraea_34H
------TCGG
640698400_C_psychrerythraea_34H
------TCGG
640698408_C_psychrerythraea_34H
------TCGG
640698416_C_psychrerythraea_34H
------TCGG
640698390_C_psychrerythraea_34H
------TCGG
DQ027051.1_Colwellia_sp_MT41
--------CG
DQ027052.1_Colwellia_sp_KT27
--------CG
DQ027056.1_Psychromonas_sp_CNPT3
------TCGG
DQ027057.1_Psychromonas_sp_HS11
------TCGG
640705772_P_profundum_SS9
AGGAGAAAGG
DQ027054.1_P_profundum_3TCK
--------CG
DQ027055.1_P_profundum_1230sf1
--------CG
640705946_P_profundum_SS9
--------CG
640705754_P_profundum_SS9
--------CG
640705856_P_profundum_SS9
AGGAGAAAGG
640705924_P_profundum_SS9
--------CG
640705919_P_profundum_SS9
--------CG
640705763_P_profundum_SS9
AGGAGAAAGG
640705741_P_profundum_SS9
AGGAAAAAGG
640705850_P_profundum_SS9
--------CG
640705738_P_profundum_SS9
--------CG
640705907_P_profundum_SS9
--------CG
640705913_P_profundum_SS9
--------CG
640705910_P_profundum_SS9
--------CG
640705881_P_profundum_SS9
--------CG
640705884_P_profundum_SS9
--------CG
DQ027053.1_Moritella_sp_PE36
--------CG
DQ027059.1_Shewanella_sp_PT48
------TCGG
DQ027060.1_Shewanella_sp_PT64
---------641466167_P_profundum_SS9
------TCGG
DQ027058.1_Shewanella_sp_KT99
------TCGG
641463346_P_profundum_SS9
------TCGG
DQ027061.1_Carnobacterium_sp_AT7
------TTTG
DQ027062.1_Carnobacterium_sp_AT12 ---------JF303756.1_Rhodobacterales_PRT1
-----GCAAG
639101207_P_profundum_3TCK
---------2504111167_HIMB59b
---------U75256.1_SAR211g2
---------AF353214.1_Arctic95B-1g2
---------2236674967_AAA288-E13
---------2236446051_AAA288-G21
---------2236452142_AAA288-N07
---------2236674298_AAA240-E13
---------2504109332_HIMB5b
---------2503352260_HTCC7211
---------2503364240_HTCC9565
---------640708248_HTCC1062
---------642513240_HTCC1002
---------X52172.1_SAR11g1b
---------U75649.1_SAR193g1b
---------Z99997.1_LD12
---------A
AB154304.1_S9D-28fresh
-------GCA
2503356127_HIMB114
-------CGG
2505687060_IMCC9063
---------U70686.1_OM155g3
----------
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAGGACGGT
GGAT-----GGATGGCGAT
GGAGGGCGTT
GGAGGGCGTT
G--------GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGAT
GGAGGGCGTT
---------GGAGGGCGTT
GGAGGGCGTT
GGAGGGCGTT
GGAG-----C
---------AGGAGGCAGC
---------------------------T
---------T
------------------------------------------------------T
---------T
---------T
---------T
-----------------TT
AGGAGGCGTT
AGGAGGCGTT
GAAGTGCGTG
-------------------
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
C-ACCACTTT
---------G-ACCACGGT
T-ACCACGGT
T-ACCACGGT
---------T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
G-ACCAC--------------------T-ACCACGGT
T-ACCACGGT
T-ACCACGGT
CAGCCGC-----------TGACCACGGT
------------------TGACTACGGT
TGACTACGGT
---------------------------------------------TGACCACGGT
TGACCACGGT
TGACCACGGT
TGACCACGGT
---------GAACTACGGT
TGACCAAGGT
TGACCAAGGT
--ACCACGGT
-------------------
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
GTGTTTCATG
---------GT-------GTGGTTCATG
GTGGTTCATG
---------GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
---------------------------GTGGTTCATG
GTGGTTCATG
GTGGTTCATG
------------TTT---GGGTTCAGCG
------------------ACGATCAGCG
ACGATCAGCA
---------------------------------------------ATAGTCAGCG
ATAGTCAGCG
ATAGTCAGCG
ATAGTCAGCG
---------ATAGTCAGCG
ATAGTCAGCA
ATAGTCAGCG
ATGATCGGCG
-------------------
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
------------------ACTGGGGTGA
ACTGGGGTGA
---------ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
---------------------------ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
-CTAAGGTG---------ACTGGGGTGA
------------------ACTGGGGTGA
ACTGGGGTG------------------------GCAA
-TTAAGGCAA
---------ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
ACTGGGGTGA
---------ACTGGGGTGA
ACTGGGGTGACTGGGGTGA
ACTGGGGTGA
-------------------
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
------------------AGTCGTAACA
AGTCGTAACA
---------AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
---------------------------AGTCGTAACA
AGTCGTA--AGTCGTAACA
---------------------------------------------AGTCGTAACA
----------------GCA
-------GCA
AG-------AG--------------GCA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
AGTCGTAACA
---------AGTCGTAACA
----------------ACA
AGTCGTAACA
-------------------
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCCT
AGGTAACCGT
AGGTAACCGT
------------------AGGTAGCCCT
AGGTAAACCT
---------AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
AGGTAGCCCT
---------------------------AGGTAGCCCT
---------AGGTAGCCCT
---------------------------------------------AGGTAGCCGT
---------AAG------AAG------------------------AGG------AGGTAGCCGT
AGGTAGCCGT
AGGTAGCCGT
AGGTAGCCGT
---------AGGTAGCCGT
---------AGGTAACCGT
AGGTAGCCGT
-------------------
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AAAGGG---AAAGGG---------------------AGGGGAACCT
------------------AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
---------------------------AGGGGAACCT
---------AGGGGAACCT
---------------------------------------------AGGGGAA-CT
------------------------------------------------------AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
AGGGGAACCT
---------AGGGGAACCT
---------AGGGGAACCT
AGGGGAACCT
-------------------
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
GGGGTTGGAT
------------------------------------GGGGCTGGAT
------------------GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
GGGGCTGGAT
---------------------------GGGGCTGGAT
---------GGGGCTGGAT
--GGACAGAT
------------------------------------GCGGTTGGAT
------------------------------------------------------GCGGCTGGAT
GCGGCTGGAT
GCGGCTGGAT
GCGGCTGGAT
---------GCGGTTGGAT
---------GCGGTTGGAT
GCGGCTGGAT
-------------------
CACCTCC--CACCTCC--CACCTCC--CACCTCC--CACCTCC--CACCTCC--CACCTCC--CACCTCC--CACCTCC--------------------------------------CACCTCCTTA
------------------CACCTCCT-CACCTCCTTA
CACCTCCT-CACCTCCT-CACCTCCT-CACCTCCTTA
CACCTCCTTA
CACCTCCT-CACCTCCTTA
CACCTCCT-CACCTCCT-CACCTCCT-CACCTCCT-CACCTCCT----------------------------CACCTCCTTA
---------CACCTCCTTA
---------------------------------------------CACCTCCTTA
------------------------------------------------------TACCT----TACCT----TACCTCCTTTACCTCCTTT
---------CACCTCCTTA
---------CACCTCCTTA
TACCT-----------------------
------------------------------------------------------------------------------------------------------------------------------------CCTA----CCTA------------------------------------------------------------CT--------------CCTAA
-------------