I. ASCRC General Education Form
Group
Group XI: Natural Sciences
Dept/Program
Course #
Pharmacy
Course Title
Prerequisite
Use and Abuse of Drugs
Credits
none
110, Section 1
110, Section 80
3
II. Endorsement/Approvals
Complete the form and obtain signatures before submitting to Faculty Senate Office
Please type / print name Signature
Instructor
David Freeman
Keith Parker
Phone / Email
x4772
Date
9/24/08
david.freeman@umontana.edu
Program Chair
Richard Bridges
Dean
David Forbes
III. Description and purpose of the course: General Education courses must be introductory
and foundational. They must emphasize breadth, context, and connectedness; and relate course
content to students’ future lives: See Preamble:
http://www.umt.edu/facultysenate/gened/GEPreamble_final.htm
The purpose of the course is to provide students with knowledge of some of the general
principles of chemistry, biochemistry and physiology that are relevant to the actions of drugs.
In addition, students learn personal and societal aspects of drug use and misuse, and become
acquainted with common terminology. These are achieved with the following course content:
1. Basic social/psychological reasons for substance abuse
2. Current methodologies for preventing and treatment of substance abuse
3. Basic physiological and biochemical theories of substance addiction and
dependence
4. Fundamentals of the nervous system at the biochemical, tissue, and organ level
5. Basic physiological and biochemical principles of drug action
6. The history, actions, side effects, mechanism of action, and toxicity of drugs that
are commonly abused and other popular medications.
IV. Criteria: Briefly explain how this course meets the criteria for the group. See:
http://www.umt.edu/facultysenate/ASCRCx/Adocuments/GE_Criteria5-1-08.htm
1. Courses explore a discipline in the natural
sciences and demonstrate how the scientific
method is used within the discipline to draw
scientific conclusions.
This course emphasizes four natural science
disciplines (i.e., physiology, pharmacology,
chemistry, and neuroscience), at a basic
level needed to understand the actions of
drugs. Students are presented with
evidence that supports the proposed
mechanisms involved in drug action, and
how chemical, biochemical, and
physiological principles are involved in drug
discovery, development, and evaluation.
2. Courses address the concept of analytic
uncertainty and the rigorous process required
to take an idea to a hypothesis and then to a
validated scientific theory.
Uncertainty in measuring drug effectiveness
is explored by presenting strategies for
designing clinical trials that help assess the
many therapeutic and toxic effects of drugs,
and other undefined, nonspecific actions
(e.g., placebo effects). Historical coverage
from lectures and the textbook give students
a perspective on the scientific process used
in drug discovery (e.g., application of
receptor theory) and underlying mechanisms
(e.g., observations from diseases).
V. Student Learning Goals: Briefly explain how this course will meet the applicable learning
goals. See: http://www.umt.edu/facultysenate/ASCRCx/Adocuments/GE_Criteria5-1-08.htm
1. understand the general principles
associated with the discipline(s) studied;
The basic principles of physiology,
pharmacology, neuroscience, and
chemistry are presented near the beginning
of course and then appropriately applied
throughout the remainder of the course
when covering different categories of drugs.
2. understand the methodology and activities
scientists use to gather, validate and interpret
data related to natural processes;
Techniques used in drug development (e.g.,
dose-response curves) and methodologies
used in clinical trials are taught.
3. detect patterns, draw conclusions, develop
conjectures and hypotheses, and test them by
appropriate means and experiments;
Receptor theory of agonists and
antagonists are presented which allow
students to predict the effects of drugs.
Properties and patterns in the chemical
structures of drugs are used to understand
the primary effects, and body distribution or
elimination of drugs.
Presenting scientific observations of the
effects of drugs on disease states and the
development of receptor theory give
students an appreciation for how
hypothesizing, logic, testing and observing
play a role in drug discovery.
General limitations in drug measurement
techniques and data, and idiosyncratic
biological responses (e.g., body
compensation) are presented.
4. understand how scientific laws and
theories are verified by quantitative
measurement, scientific observation, and
logical/critical reasoning;
5. understand the means by which analytic
uncertainty is quantified and expressed in the
natural sciences.
VII. Syllabus: Paste syllabus below or attach and send digital copy with form. ⇓ The syllabus
should clearly describe how the above criteria are satisfied. For assistance on syllabus
preparation see: http://teaching.berkeley.edu/bgd/syllabus.html
Attached
*Please note: As an instructor of a general education course, you will be expected to provide
sample assessment items and corresponding responses to the Assessment Advisory Committee.
PHARMACY 110
Autumn 2008
USE & ABUSE OF DRUGS
Time & Place
Mon, Wed, Fri @ 2:10–3:00 pm, SB 169
Course Coordinators
David Freeman
david.freeman@umontana.edu
Keith Parker
Office: SB 308; e-mail:
Office: SB 271; e-mail: keith.parker@umontana.edu
Course Instructors
Katie George
kathleen.george@umontana.edu
John Gerdes
Fernando Cardozo-Pelaez
Sandra Wells
sandra.wells@umontana.edu
Office: SB 481; email:
Office: SB 478; e-mail: john.gerdes@umontana.edu
Office: SB 244; e-mail: fernando.cardozo@umontana.edu
Office: SB 285C; e-mail:
Text Drugs, Society and Human Behavior, Ksir, Hart & Ray, 12th edition
Students will be expected to access course materials from Blackboard and the text publisher’s web site.
This course satisfies 3 credits of General Education Requirements in the Natural Sciences Perspective.
Date
Instr. Chap.
M 8/25
kp
1
Overview
W 8/27
kp
“
kp
F 8/29
Social Problem
W 9/3
kp
& Regulation
F 9/5
kp
“
M 9/8
df
System
W 9/10
df
“
F 9/12
df
“
M 9/15
df
Drugs
W 9/17
df
F 9/19
df
”
M 9/22
kp
W 9/24
F 9/26
fc
Topic
Drug Use: An
1
“
2
Drug Use as a
3
Drug Products
3
4
Nervous
4
“
4
5
5
5
11
1-4
6
“
Exams: The course has 4 mid-semester exams and a
comprehensive final. The course grade will be based on a
student’s best three mid-semester exams and the final. All
exams must be taken on the scheduled days and times.
All students must take the final.
Grading:
• The course is graded on a curve.
• The plus/minus grading system will be used.
• Graded in-class assignments may be given.
Date
“
Actions of
“
Caffeine
EXAM 1
Stimulants
M 9/29
fc
6
Stimulants
W 10/1
fc
6 Methamphetamine
video
F 10/3
kp
7
Depressants
M 10/6
kp
7
Depressants
W 10/8
kp
8
Drugs for
Mental Disoreders
F 10/10
kp
8
“
“
M 10/13
df
13
Opiates
W 10/15
5-7,11
EXAM 2
F 10/17 df
13 Opiates
Instr. Chap.
M 10/20 jg
W 10/22 jg
F 10/24 fc
M 10/27
W 10/29
Drugs
F 10/31
M 11/3
W 11/5 sw
F 11/7
M 11/10
W 11/12
F 11/14
M 11/17
Supplements
W 11/19 df
F 11/21
M 11/24 kp
M 12/1
Abuse
W 12/3
F 12/5
Abuse
14
14
15
fc
kg
kg
sw
Topic
Hallucinogens
“
Marijuana & Hashish
15
“
16 Performance Enhancing
16
9
9
sw
sw
sw
df
9
“
10 Tobacco
8,13-16 EXAM 3
10
Tobacco
12 OTC’s & Dietary
12
kp
kp
kp
“
Alcohol
“
17
“
Oral Contraceptives
“
Preventing Substance
9,10,12 EXAM 4
18 Treating Substance
and Course
Evaluation
W 12/10
1-18
FINAL
1:10-3:10 PM
COMPREHENSIVE
Students are responsible for picking up exam results to
verify grading of exams. Any discrepancies must be
reported to the course coordinator within ten days after
the exam scores are posted. Grade reports are
distributed in the 3rd floor lobby of the Skaggs
building, near room 374.
Students seeking General Education Credit for the
course must register for a traditional (letter) grade.
For each exam, please bring:
• Scantron Wide Form F-288 from the bookstore,
• #2 pencils with good erasers,
• UM ID Card
Attendance
• Class attendance is strongly encouraged but is not required. However, you will be
responsible for all material presented in class, including changes made to the syllabus
or exam schedule.
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•
•
•
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Using the Web in this course
Instructor Materials
The course instructors will place PowerPoint, Word, and other instructional materials
on UM BlackBoard.
Students are encouraged to copy these materials, if they are available, and bring them
to class.
If you have copies of the materials, then you can listen to the lecture and add additional
notes as necessary.
Accessing Blackboard
Click the Blackboard Login icon under Quick Links on the UM Homepage
Login using your UM Username and Password. Login help is accessible from the
Blackboard Login page.
Textbook Web Materials
Access the McGraw-Hill site for the 12th editions is at www.mhhe.com/ksir11e
Useful information under Student Edition: By Chapter
General Education and Learning Outcomes
• The primary purpose of this course is for you to gain an understanding of the actions of
drugs of abuse.
• This is achieved by the following learning outcomes. Students will understand:
• Basic social/psychological reasons for substance abuse
• Current methodologies for preventing and treatment of substance abuse
• Basic physiological and biochemical theories of substance addiction and
dependence
• Fundamentals of the nervous system at the biochemical, tissue, and organ level
• Basic physiological and biochemical principles of drug action
• The history, actions, side effects, mechanism of action, and toxicity of the
following drugs:
Stimulants, Depressants, Drugs for Mental Disorders, Alcohol, Tobacco,
Caffeine, OTC drugs,
Opiates, Hallucinogens, Marijuana, Drugs used in sports, Oral
Contraceptives
• Fundamental concepts of physiology, pharmacology, neuroscience, and chemical
science are introduced.
• Students learn about the “scientific method” through exploration of the discovery,
development, modification and use of drugs.
Study Guide
• The following information is presented in the text and lecture for each drug category
(Chapters 6-16),
and is the basis for examinations over this material.
• Different aspects may be emphasized for each drug category, depending upon their
importance to your understanding of the actions and use of the drug.
• History of the drug
• What the drug does:
Actions of the drug
Side effects of the drug
Toxic effects of the drug
• How the drug acts (its mechanism of action):
The neurotransmitter, receptor, or enzyme that the drug affects
How (in what manner) the drug affects the receptor (agonist, blocker, etc)
• Use of the drug as a therapeutic agent in medical practice
• How the actions or use of different drugs in a category compare
• Special problems and considerations with the drug
• Students are encouraged to study:
• The textbook
• Class lecture notes