I. ASCRC General Education Form
Group
Group XI Natural Science
Dept/Program
Chemistry
Course Title
Prerequisite
Course #
Organic and Biological Chemistry
Chem 151, C- or better
Credits
CHEM 152
3 credits
II. Endorsement/Approvals
Complete the form and obtain signatures before submitting to Faculty Senate Office
Please type / print name Signature
Date
Holly Thompson
x2070/holly.thompson@
umontana.edu
Program Chair
Mark Cracolice
Dean
Gerald Fetz
III. Description and purpose of the course: General Education courses must be introductory
and foundational. They must emphasize breadth, context, and connectedness; and relate course
content to students’ future lives: See Preamble:
http://www.umt.edu/facultysenate/gened/GEPreamble_final.htm
Instructor
Phone / Email
The Chem 150 series (Chem 151N, 152N and 154N) provides a one year survey of chemistry.
Chem 154, the lab component of the series, coordinates with Chem 152, and is taken by most
of the Chem 152 students.
Chem 152 explores the molecular logic of living organisms. Students learn the structures of
organic compounds, and then use "first principles" (fundamental characteristics) to predict
physical properties and chemical reactivities of small organic compounds. The logic learned
with these simple organic structures is then applied to the more complex molecules that are
made and used by living organisms. In addition to biological examples, the molecular logic is
applied to aspects of the global carbon cycle.
IV. Criteria: Briefly explain how this course meets the criteria for the group. See:
http://www.umt.edu/facultysenate/ASCRCx/Adocuments/GE_Criteria5-1-08.htm
Chem 152 is not a course on how to apply
the scientific method. It is primarily focused
on foundational content knowledge and use
of that knowledge to draw conclusions about
behavior of complex molecules in living
organisms. However, examples of specific
experiments are used throughout the course
to illustrate both questions raised by
empirical observation and validation of
biochemical theories.
V. Student Learning Goals: Briefly explain how this course will meet the applicable learning
goals. See: http://www.umt.edu/facultysenate/ASCRCx/Adocuments/GE_Criteria5-1-08.htm
Learning goals 1,2, and 4 are achieved
primarily through the three lectures per
week, assigned practice problems, and
biweekly exams. One important component
of the early lectures is the use of a molecular
model kit, purchased with the textbook.
Homework requiring students to explore
characteristics of small organic molecules
with their model kits is assigned frequently.
Biochemical problem-solving skills
(recognition and detection of patterns,
drawing conclusions, developing
conjectures and hypotheses) are developed
in recitation. Students meet once a week to
work on open-book exercises in small
groups. Each recitation exercise typically
starts with practice of the content
knowledge and then progresses to
application of that knowledge to real-world
problems drawn from biology, medicine,
agriculture and geochemistry (global carbon
cycle).
The Chem 152 final exam provides an
opportunity for students to synthesize what
they have learned throughout the semester
and practice their biochemical problemsolving skills. The last week of classes,
students are given a worksheet leading them
through application of the familiar
molecular logic to new biological problems.
Students are invited to discuss the
worksheet problems with their 152
colleagues. Each student must write the
exam individually during the scheduled final
exam period, without recourse to notes or
discussion.
VII. Syllabus: Paste syllabus below or attach and send digital copy with form. ⇓ The syllabus
should clearly describe how the above criteria are satisfied. For assistance on syllabus
preparation see: http://teaching.berkeley.edu/bgd/syllabus.html
CHEM 152 Fall 2008
Organic and Biological Chemistry
Dr. Holly Thompson
office hrs: Monday 9:10-10am, Tuesday 11:10-12am and by arrangement
Please email me to arrange an appointment if you have conflicts
w/ office hrs.
office:
CP 402
phone:
x2070
e-mail:
Chem 152N satisfies Perspective 6, Natural Sciences, for the general
education requirement. This course explores the molecular logic of living
organisms. Fundamental chemical and physical properties of simple
organic compounds are responsible for the organization and function of
living organisms: cell structure, energy flow, replication of DNA, etc. Chem
152 students study some of the fundamental properties of organic
compounds and examine how these properties affect the activity of
biological molecules. Students learn how to apply patterns of
structure/function relationship in known carbohydrates, lipids and proteins
to new examples, using logical and critical reasoning.
The prerequisite for Chem 152 is a grade of “C” or better in Chem 151 or
permission of the instructor. Good alternatives include “C” or better in 161
or general chemistry courses from other colleges or universities. Cyberbear
doesn’t screen for your chemistry background, but please set yourself up
for success.
Chem 154 is the Organic and Biological Chemistry Lab course that
accompanies Chem 152. Most, but not all, majors require Chem 154.
There are advantages to taking the lab concurrently with Chem 152: many
152 concepts are practiced and reinforced in lab, and the lab is easier while
the concepts are fresh in your mind. However, if your schedule does not
accommodate the lab this semester, you can take 154 next year. (Hang on
to your textbook!)
Text:
required
Introduction to General, Organic and Biological
Chemistry, 8th edition,
Bettleheim, Brown, Campbell and Farrell
Assigned reading and problems are posted on the eres
site.
Solutions Manual:
Answers to odd-numbered back-of-the-chapter
required
problems are found in the
back of the textbook. Solutions to the problems are found
in the black & white section at the end of the textbook
package (notice that the first few pages are corrections to
errors in the rest of the section).
Model Kit:
required
Chem 152 model kit
Lecture Notes:
The lecture notes for each week will be put on electronic
reserve by Monday of the following week. You can find the
electronic reserve materials at
http://eres.lib.umt.edu/eres. The password for our course
site is CHEM152.
Study Guides:
Study Guides will be posted on eres on Monday before
the exam. Each exam covers only material through the
previous week’s lectures. Exams are cumulative
throughout the semester.
Weekly Schedule
Lectures:
Recitations:
Help Sessions:
Exams:
TWRF(3 days)
8:10-9:00am CP 123
M
see information for individual sections
F
8:10-9:00 alternate weeks, see schedule
below CP 123
W
8:10-9:00 alternate weeks, see schedule
below CP 123
The jingle of cell phones, private conversations during the lecture and early
departures from the classroom are disruptive. Please respect your
colleagues. If either issue becomes a problem during the semester, I will
institute pop quizzes or other appropriate responses.
Course Assessment:
Recitation exercises are open-book worksheets. Please bring your
textbook, class notes and model kit to recitation. You are encouraged
to work with a partner; talking about chemistry is a great way to check
your understanding. Please go to the recitation section in which you are
officially enrolled. See me if you have a conflict and we will try to
accommodate your schedule. The exercises are designed to take ~40
minutes. You must turn in exercises at the end of the period to get credit.
Some of the exercises require you to build models and show them to the TA
for credit.
Exams are multiple choice, 25 questions worth 4 pts each. Most students
find that 50 minutes provides plenty of time to complete the exam. Help
sheets, periodic tables and calculators are not permitted.
Grading is based on the scantron forms, not the written copy of the exam.
The written copy of your exam plus a report sheet with your score and the
exam key will be returned to you.
Exams
There are six regular 100 pt exams. The lowest of these exams
will be dropped, for a total of 500 possible pts. The last regular
exam is shorter (worth 50 pts) and cannot be dropped.
If you miss an exam due to legitimate excuse (illness, field trip,
etc), you must contact me BEFORE the exam to arrange a makeup exam. Make-up exams will be a mixture of short-answer and
multiple choice problems.
DSS Students - please email me the first week to qualify for
accommodations.
Recitations There are fourteen 10 pt recitations. The lowest three will be
dropped for a total of 110 possible pts from the recitations.
There are no make-up recitations. However, be sure to get a
copy of any missed recitation exercise.
Final Exam The final exam is scheduled for 8:10-10:00 am on Tuesday,
Dec 9. The final exam is worth 100 pts and cannot be dropped.
Please schedule your plane reservations, etc for after this time.
No early finals!
You will be provided with a worksheet to guide your studying for
the comprehensive final exam.
Getting to Letter Grades
The points from exams I-VI (500), exam VII (50), recitations (110) and
final exam (100) will be added together, for a total of 760 possible pts.
Letter grades will be assigned as follows:
∃93.33% guarantees A
∃90.00% guarantees A∃86.67% guarantees B+
∃83.33% guarantees B
∃80.00% guarantees B∃76.67% guarantees C+
∃73.33% guarantees C
∃70.00% guarantees C∃66.67% guarantees D+
∃63.33% guarantees D
∃60.00% guarantees D<60.00% guarantees F
Student Conduct
All students must practice academic honesty. Academic misconduct is
subject to an academic penalty by the course instructor and/or a
disciplinary sanction by the University. All students need to be familiar with
the Student Conduct Code. The Code is available at
http://www.umt.edu/SA/VPSA/indec.cfm/page/1321 .
The majority of Chem 152 students are honest and responsible. Be advised
that I do enforce the Student Conduct Code in order to protect the honest
students from academic misconduct.
Dates
Topics Covered (approximate) and Exam Dates (definite)
M
T
W
R
F
8/25
8/26
8/27
8/28
8/29
recitation 1
introduction
alkanes & isomers
alkanes & isomers
help session, how to succeed in biochemistry
M
T
W
R
F
9/01
9/02
9/03
9/04
9/05
Labor Day, no classes
functional groups
functional groups
functional groups
help session
M
T
W
R
F
9/08
9/09
9/10
9/11
9/12
recitation 2
polarity, intermolecular attraction, solubility
Exam I
polarity, intermolecular attraction, solubility
acid-base chemistry
M
T
W
R
F
9/15
9/16
9/17
9/18
9/19
recitation 3
acid-base chemistry
redox chemistry
redox chemistry
help session
M
T
W
R
F
9/22
9/23
9/24
9/25
9/26
recitation 4
redox chemistry
Exam II
chirality
chirality
M
T
W
R
F
9/29
9/30
10/01
10/02
10/03
recitation 5
chirality
linkages
linkages
help session
W
R
F
10/08
10/09
10/10
10/06
recitation 6
10/07
linkages
30th
instructional day, last day to drop/add
Exam III
linkages
carbohydrate chemistry
M
T
W
R
F
M
T
10/13
10/14
10/15
10/16
10/17
10/20
recitation 7
carbohydrate chemistry
carbohydrate chemistry
carbohydrate biology
help session
recitation 8
10/21
carbohydrate biology
W
R
10/22
Exam IV
M
T
10/23
carbohydrate biology
F
10/24
lipids
M
T
W
R
F
10/27
10/28
10/29
10/30
10/31
recitation 9
lipids
lipids
lipids
help session
M
T
W
R
F
11/03
11/04
11/05
11/06
11/07
recitation 10
Election Day, no classes
Exam V
proteins
proteins
M
T
W
R
F
11/10
11/11
11/12
11/13
11/14
recitation 11
Veterans Day, no classes
proteins
proteins
help session
M
T
W
R
F
11/17
11/18
11/19
M
T
W
R
F
11/24
11/25
11/26
11/27
11/28
recitation 13
enzymes
Exam VI
nucleic acids
nucleic acids
M
T
W
R
F
12/01
12/02
12/03
12/04
12/05
recitation 14
regulation of gene expression
regulation of gene expression
Exam VII (50 pts)
review, wrap-up
T
12/09
Final Exam 8-10am
No early exams will be given.
recitation 12
enzymes
Thanksgiving Holiday
11/20
“
11/21
“
Assigned Reading and Problems from the Text Edition 8
Please assume that any problems embedded in sections of the text
assigned for reading are important. The problems listed below do not
include these embedded problems.
Lecture 1 Alkanes and Isomers
reading:
ch 10.1-3; ch 11.1-6, 8A; ch 12.2B
problems: 10.7-10, 10.12-15, 10.17; 11.10-16,(*use your model kit to
help solve 11.16)
20, 23(a,b,c,f), 24(all except e), 25-32, 41, 52-53; 12.21-27
If you are looking for more review of fundamental concepts:
4.50(a,c,e), 51, 53(a,b,c,e), 54, 61
Lecture 2 Functional Groups
reading:
ch 10.4; ch 12.1-3; ch 14.1A,B; ch 17.1, 2A;
ch 16.1-2A; ch 13.1-2; ch 14.4A,B
ch 18.1-2A;
problems: 10.18-36, 40, 43-45, 49-51; 12.11-20, 29-30, 55-56, 57(b),
57-58;
14.8-11, 12(c,d,e,f), 13(b,c,d,e,f), 14-15, 57, 66(a);
17.9, 12-15, 16(b,c,e,f), 17(a,b,c,d,f), 18(a,b,c), 19-20, 56, 58,
59(a,b,c,d,e,f), 68a;
18.4 (except chiral question), 5(a,b,c), 6(a,b), 7(b,c,d), 18(a);
16.6,7,9(all except e),10 (a,b,d), 11-2, 13(a,b), 14(a), 28, 29,
40(a,b,c,e); 11.17-19(all);
13.2-10,(*why is the first part of the answer to 5 not correct,
what is the evidence for your argument?),12(b,g,h),
13(a,b,d,f),14, 15, 40-41; 14.41
Lecture 3 Polarity, Intermolecular Attraction and Solubility
reading:
review ch 4.4-5, 7,9A, 10,-11 and Tables 4.5, 4.6, 4.8;
new 11.7; 12.4; 14.1c; 16.3; 17.3; 18.3-4
problems: 4.31, 4.72, 4.79-80
10.46-48; 11.33-39, 54-55; 14.16-26, 56, 59-62;
16.15-18, 43-44; 17.21-26, 60-61; 18.12-18
Lecture 4 Acid-Base Chemistry
Chapter 9 is well-written; please review 9.1-5, 9.7-8 (we won’t use ion
product of water or pOH), 9.10-11.
reading:
ch 18.5A,B;
ch 16.4-5; chemical connections 16D
problems: 18.21-23, 26-29, 31, 37(b,c); 16.21-22, 23(pKb=3.2, so
pKa=10.8, use pKa to solve), 16.25-6, 45, 47(b,c), 48, 51
Lecture 5 Redox Chemistry
reading:
ch 14.2B,C;
ch 17.4A;
ch 12.6 B,D
problems: 14.31-34; 17.27-33, 36(a,c,d), 37(a,c,d), 62;
34(b,e,f), 36(b), 38(a), 41-43, 46(a,b), 60-62
Lecture 6 Chirality
12.33(b),
reading: ch 15.1-5
problems: 15.7-10, 12-33
Lecture 7 Linkages
reading: ch 19.1-5; ch 17.4C
problems: 19.6-7, 10-12, 16-23, 25-27, 36-37; 17.41
Lecture 8 Carbohydrate Chemistry
reading: ch 20.1-4, ch 20.5 first paragraph
problems: 20.6-20, 22-31, 33, 39-43, 49
Lecture 9 Carbohydrate Biology
reading: ch 20.4-6
problems: 20.38, 46-48, 54-59, 62-63
Lecture 10 Lipids
reading:
ch 21 sec 1-12
problems: 21.2-24, 25 (ceramide = sphingosine+fa), 26-27, 28 (use the
lecture notes rather than solutions manual, which provides only
part of the answer), 30-33, 36-37, 39-44, 46-51, 64-70, 72-78
Lecture 11 Proteins
reading: ch 22.1-12
problems: 22.3-21, 23-41, 44, 46-48, 50-58, 70, 72-73, 75-78
Lecture 12 Enzymes
reading:
ch 23.1, 3 (cofactors, coenzymes, substrates, active sites; don’t
worry about the other terms in this chapter), 4, 5C, 6; Chemical
Connections 23C
problems: 23.1-6, 11-12, 16. 19-20, 29-30, 32, 56-57, 70-71
Lecture 13 Metabolism
reading: ch 27.1-7; ch 28.1, 2(A,B), 5,
problems: 27.1-2, 6-7, 29-30, 35-36; 28.2-3, 12
Lecture 14 Nucleic Acids
reading: ch 25.1-6
problems: 25.2-7, 16-18, 20, 23, 27-31, 49-50
Lecture 15 Regulation of Gene Expression
reading: ch 26.6
problems: 26.33, 36
*Please note: As an instructor of a general education course, you will be expected to provide
sample assessment items and corresponding responses to the Assessment Advisory Committee.