D
Demystifying
tif i the
th Grant
G
t Process:
P
AHRQ Funding Opportunities
Francis D. Chesley, Jr., M.D.
Director Office of Extramural Research
Director,
Research,
Education and Priority Populations
June 27,, 2010
AHRQ
Q Mission and Vision
AHRQ Mission
To improve the quality, safety,
efficiency,
y, and effectiveness of
health care for all Americans
AHRQ Vision
As a result of AHRQ's efforts,
American health care will
provide services of the highest
quality, with the best possible
outcomes, at the lowest cost
www.ahrq.gov
HHS Organizational
g
Focus
NIH
CDC
AHRQ
Biomedical
research to
prevent,
diagnose and
treat diseases
Population health
and the role of
community--based
community
interventions to
improve health
Long-term and
Longsystemsystem
y
-wide
improvement of
health care quality
and effectiveness
AHRQ Research Focus:
H
How
it Diff
Differs
 Patient
Patient--centered,
centered not diseasedisease-specific
 Dual Focus -- Services + Delivery Systems
Effectiveness research focuses on actual daily
practice, not ideal situations (“efficacy”)
 AHRQ mission includes p
production and use of
evidence--based information
evidence
FY 2010 Budget Highlights: New
Resources,
Resources Ongoing Priorities
$397 million allocation for FY 2010 represents a
$25 million increase over FY 2009
 MRSA Research: $9M
 Prevention
P
ti and
dC
Care M
Management:
t $15
$15.9M
9M
 Comparative Effectiveness Research: $21M
 Investigator
Investigator--Initiated Research: $23
$23.6M
6M
 Medical Liability Reform Demonstrations: $25M
 HAI Prevention Activities: $25
 Health IT: $27.6M
 Medical Expenditure Panel Survey (MEPS): $58.8M
 Patient Safety: $90.6M
AHRQ’s Fiscal 2011
Budget Proposal
 Obama Administration proposed FY 2011
budget includes $611 million for AHRQ – up
from $397 million in FY 2010:
– $286 million for patientpatient-centered health
research (aka CER), up $261 million over the
FY 2010 budget
– $32 million for health information technology
research a $4 million increase from FY 2010
research,
– $65 million for patient safety research, including
$34 million to reduce and p
prevent healthcarehealthcareassociated infections
AHRQ
Q Portfolios
 Value
– Goal: Support the
development of health care
activities that help reduce
unnecessary waste while
improving quality
Comparative
Effectiveness
Innovations/Emerging
Issues
 Innovations/Emerging
I
ti
/E
i
AHRQ
Issues
– Goal: Identify
y and support
pp
ideas and projects that
have the potential for
highly innovative solutions
to health care challenges
Prevention and
Care Management
Patient Safety
y
Value
Health IT
HHS Framework for CER
Evidence
Generation
Horizon
Scanning
Evidence
Need
Identification
Evidence
Synthesis
Strategies
Interventions
Conditions
P
Populations
l ti
Dissemination
Translation
Research Platform
Infrastructure – Methods Development – Training
Improvements
in
Health Care
An Unprecedented
p
Investment
Allocations for the $1.1 billion in
comparative effectiveness research
funding in the American Recovery and
Reinvestment Act off 2009:
 Research
 Data Infrastructure
 Dissemination and
 $681M (62%)
 $268M (24%)
 $132M (12%)
Adoption
 Administrative
support, inventory,
e al ation
evaluation
 $19M (2%)
21st Century
y Health Care: Training
g
 AHRQ has allocated $20 million in Recovery Act
funding for career development of clinicians and
research doctorates focusing on comparative
effectiveness
ff ti
research.
h Examples:
E
l
– NRSA Postdoctoral Comparative Effectiveness
Development Training Award (T32)
 Two years of supervised study and research for two
cohorts of clinical and research doctorates
– Mentored
M t
d Clinical
Cli i l Scientists
S i ti t Comparative
C
ti
Effectiveness Development Award (K12)
 Three y
years of supervised
p
study
y and research for one
cohort of clinical and research doctorates
Grant Opportunities
pp
 Pre and Postdoctoral Training
– NRSA Institutional Training Programs (T32)
– NRSA Predoctoral Fellowships for
Underrepresented Minority Students (F31)
– NRSA Postdoctoral
P td t l Fellowships
F ll
hi (F32)
– Dissertation Grants (R36)
 Career Development Awards
– Mentored Clinical Scientist Awards (K08)
– Mentored Research Scientist Development
Award (K01)
– Independent
I d
d t Scientist
S i ti t A
Awards
d (K02)
Mentored Research Scientist
Awards ((K01))
 Audience – research trained
doctorates (e.g., Ph.D., Sc.D., Dr.P.H.)
who require mentoring and have
potential to develop into independent
investigators
 Duration -- 3 to 5 years
years,
nonrenewable
 Level of Support -- $90,000
annually, plus fringe benefits and
research development support up to
$25 000
$25,000
Mentored Clinical Scientist
Awards ((K08))
 Audience -- clinical doctorates
(including those in patientpatient-oriented research)
who require mentoring and have
potential to develop into independent
investigators
 Duration -- 3 to 5 years
years,
nonrenewable
 Level of Support -- $90,000
annually, plus fringe benefits and
research development support up to
$25 000
$25,000
Independent Investigator Awards
((K02))
 Audience -- promising new clinical and
nonclinical investigators who are out of
training 5 years or less, with demonstrated
need of intensive research focus
 Duration -- 3 to 5 years, nonrenewable
 Level of Support -- $90,000 annually, plus
fringe benefits, travel, justified educational
expenses
Special Emphasis for Career
p
Development
 AHRQ Announces Interest in Career
Development (K01, K02, K08) Grants
focused on Health Care Associated
I f ti
Infections
in
i Ambulatory
A b l t
C
Care S
Settings
tti
 AHRQ Announces Interest in Career
Development (K01
(K01, K02
K02, K08) and
Dissertation (R36) Grants focused on
Health
ea t Information
o at o Technology
ec o ogy ((IT))
 Special Emphasis Notice (SEN): AHRQ
Announces Interest in Grants Focused
on Health Risk Assessment in Primary
Care Settings
Ongoing
g
g Research Priorities
 PA
PA--09
09--071 AHRQ Health Services Research
Demonstration and Dissemination Grants
(R18)
 PA
PA--09
09--070 AHRQ Health Services Research
Projects (R01)
 PAR
PAR--08
08--136 Researching
g Implementation
p
and
Change While Improving Quality (R18)
 PA
PA--06
06--448
448AHRQ
AHRQ Small Research Grant
Program (R03)
Policy
y Relevant Topics
p
 See FOAs for specific priorities, but also
 Advancing the science of how
organizational structure, process
reengineering and behavioral incentives
can improve outcomes
 Improving delivery system performance
on quality and other outcomes
 Advancing implementation and spread
off best
b t practices
ti
Engaging Federal Staff in the
Grant Process
 Importance
p
of Concept
p Papers
p
– Alignment with agency priorities
– Link to specific FOA
– PO connection
 Next Steps for Applications in the Competitive
Range
– Submitting a summary statement response
– Resubmission vs. waiting
 AHRQ Funding Decisionmaking Process
– Second level review
– AHRQ Senior Leadership Team (SLT)
– Scientific merit
merit, program priorities,
priorities & balance
Tips
p for Success
 Know Electronic Application Process




(424 R&R)
Know the Funding Agency and Staff
Understand Agency Budget &
Research Priorities
Know the Grant Mechanisms
Know the Grant Process and Key
Changes
Contact Information
AHRQ WEBSITE
www.ahrq.gov
qg
F
Francis
i D
D. Ch
Chesley,
l
JJr., M
M.D.
D
(301) 427427-1521
Francis.Chesley@ahrq.hhs.gov
Questions
?