A Longitudinal Analysis of the Relationships between Neighborhood SES, Neighborhood Residential Stability, and Mortality among Women in the U.S. Chloe E. Bird Eibner C, Shih RA, Griffin BA, Slaughter ME, Dubowitz T, Escarce JJ, Margolis K, Mouton C, Whitsel E AcademyHealth June 26, 2010 Does Neighborhood SES Influence Mortality Risk in Women? • A substantial literature links neighborhood SES (NSES) characteristics to individual’s health, even adjusting for their income or education • Our prior work has linked NSES to risk of coronary heart disease (CHD) and CHD mortality, adjusting for SES, medical history and health behavior • Here, we use national longitudinal data to examine whether NSES and residential stability are associated with mortality risk in women 2 6/26/2010 How Might Neighborhood Socioeconomic Status (NSES) Affect Mortality Risk? • Increased exposure to stressors such as violence and poverty • Reduced availability to outlets for nutritious food and physical activity • Reduced access to quality health care services • Increased exposure to environmental pollutants 3 6/26/2010 How Might Residential Stability Affect Mortality Risk? • Neighborhoods with lower residential stability may have less trust and weaker social ties • Less stable neighborhoods may yield more negative interactions and less support among residents • Residential stability may explain or confound the relationship between NSES and mortality. 4 6/26/2010 Data • • Geo-coded WHI Clinical Trial N=50,498 women, age 50-79 Followed for up to 12 years Data from 76 U.S. sites Census data NSES data at the census-tract level Residential stability at the census-tract level 5 6/26/2010 Components of NSES Index • Median household income • Adults ≤ high school education (%) • Male unemployment (%) • Households with income below poverty (%) • Households receiving public assistance (%) • Households headed by a single female (%) 6 6/26/2010 Residential Stability Measure of the percentage of census-tract residents who were living in the same home 5 years earlier. 7 6/26/2010 Outcome All-cause mortality 4.67% (n = 2365) 8 6/26/2010 Methods • Cox Proportional Hazard models • Adjusted for baseline individual-level Socio-demographic characteristics Related comorbid conditions Health behaviors Family history of MI • Accounted for geographic clustering • Assessed 3 potential mediators of neighborhood effects Abuse in the past year Depression Living alone 9 6/26/2010 Baseline Characteristics • Race/ethnicity 81% non-Hispanic white 9 % non-Hispanic black 4% Hispanic • 61% Married • 94% ≥ High school • Household income 40% ≤ $34,999 $35,000 - $74,999 ≥$75,000 41% 17% 10 6/26/2010 Lower NSES and Lower Residential Stability are Independently Associated with Increased Hazard of Mortality 1.5 1.4 Hazard Ratios 1.3 1.2 1.1 1 0.9 0.8 0.7 0.6 0.5 NSES Residential Stability Abuse 11 6/26/2010 Results In a Real World Context Northwest DC Southeast DC 12 6/26/2010 Mortality Hazard Ratios: Northwest vs. Southeast DC 1.10 Hazard Ratios 1.00 0.94 0.90 0.80 0.79 0.70 0.60 0.50 NSES Residential Stability 13 6/26/2010 Limitations • Limited generalizability of the WHI sample • Longitudinal analysis not sufficient to infer causality • Healthier individuals may choose to live in better neighborhoods 14 6/26/2010 Conclusions • Living in a higher NSES neighborhood or with greater residential stability is associated with lower mortality risk among older women • The protective effect of living in a neighborhood with higher residential stability suggests that social aspects of communities are salutary • The effects of NSES and residential stability were not modified by race/ethnicity, income or education 15 6/26/2010 Implications • Future research should examine mechanisms thorough which neighborhood characteristics influence health and risk of death • Social policies targeting neighborhood characteristics may improve both individual and population health • Medical and public health efforts should include more aggressive screening of women living in low NSES neighborhoods 16 6/26/2010 Collaborators Chloe Bird, PI Karen Margolis Christine Eibner, co-PI Charles Mouton Regina Shih Tamara Dubowitz Jose Escarce Mary Ellen Slaughter Beth Ann Griffin Eric Whitsel Study funded by NHLBI R01HL084425 The authors declare no conflict of interest 17 6/26/2010 18 6/26/2010