Monique J. LeMieux
1301 Akron Ave
MS1240
Lubbock, TX 79409
EDUCATION:
2012-Present
Telephone: 806-742-3068 Ext. 250
Email: monique.lemieux@ttu.edu
Ph.D. Nutritional Sciences, Texas Tech University, Lubbock, TX
Department of Nutrition, Hospitality, and Retailing (NHR)
College of Human Sciences
2008-2012
M.S. Life Sciences, University of Tennessee, Knoxville, TN
Graduate School of Genome Science and Technology (GST)
Graduate School of Medicine
2004- 2008
B.S. Biology, Christopher Newport University, Newport News, VA
Minor: Chemistry
Honors: Omicron Delta Kappa, Christopher Newport University Chapter
Beta Beta Beta Biological Honors Fraternity, Psi Sigma Chapter
Dean’s List, four semesters
DISSERTATION RESEARCH:
2012-Present
Texas Tech University, Lubbock, TX
College of Human Sciences, NHR Department
Mentor: Dr. N. Moustaid-Moussa
Obesity is a major epidemic in the United States and worldwide and is associated
with several comorbidities including the metabolic syndrome (hypertension,
hyperglycemia etc). My dissertation focuses on researching the link between the
renin-angiotensin system, obesity and insulin resistance as well as related
nutritional interventions.
THESIS RESEARCH:
2009-2012
Conformational Diseases and Therapeutics Laboratory
University of Tennessee Medical Center, Knoxville, TN
Graduate School of Medicine,
Mentor: Dr. V. Berthelier
Thesis Title: Designing Protein Expression and Purification Systems for
Recombinant Z Alpha1-Antitrypsin using the Methylotrophic Yeast,
Pichia pastoris
Polymerization of Z α1-Antitrypsin has been linked with emphysema and
cirrhosis. However in order to conduct the necessary experiments to study this
polymerization, large of amounts of protein are needed. My thesis focused on
developing protein expression and purification systems for recombinant wildtype and mutant α1-Antitrypsin using Pichia pastoris.
LEMIEUX, MONIQUE J.
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RESEARCH EXPERIENCE:
2012- Present
Graduate Research Assistant
 “Obesity and metabolic disorders, adipocyte biology and nutrient-gene
interactions”
Nutritional Sciences; NHR Department
Texas Tech University, Lubbock, TX
Mentor: Dr. N. Moustaid-Moussa. Aug. 2012-Present
2008- 2009
Rotational Graduate Research Assistant
 “Biochemical analysis of Methyl-Mercury in Sulfur-Reducing Bacteria”
Microbial Ecology & Physiology, Biosciences Division
Oak Ridge National Laboratory, Oak Ridge TN
Mentor: Dr. M. Podar. June-July 2009

“Kinetic Analysis of an Intrinsically Disordered Domain in Vitronectin
and its role in binding to PAI-1”
Biochemistry & Cellular and Molecular Biology Department,
University of Tennessee, Knoxville, TN
Mentor: Dr. C. Peterson. May-June 2009

“Molecular Basis of the Obesity QTL, tabw2 in TallyHo Mice
Nutrition Department
University of Tennessee, Knoxville, TN
Mentor: Dr. JH Kim Jan. –May 2009
 “The Identification of Compounds that Inhibit PolyAlanine Aggregation”
Conformational Diseases & Therapeutics, Graduate School of Medicine
University of Tennessee Medical Center, Knoxville, TN
Mentor: Dr. V. Berthelier Aug.-Dec. 2008
2005-2008
Undergraduate Research Assistant
 “Genetic Analysis of Isolated Cotton Stainer Populations”
Biology, Chemistry & Environmental Science Department
Christopher Newport University, Newport News, VA
Mentor: Dr. L. Webb. Jan-May 2008

“External Survey Methods Used for Monitoring Bat Activity”
Biology, Chemistry & Environmental Science Department
Christopher Newport University, Newport News, VA
Mentor: J. Warren and Dr. R. Sherwin. Aug-Dec. 2007

“Dolphin Fin Comparison and Analysis through FinScan”
Biology, Chemistry & Environmental Science Department
Christopher Newport University, Newport News, VA
Mentor: K. Foss and Dr. J. Reed. Jan.-May 2005
LEMIEUX, MONIQUE J.
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TEACHING EXPERIENCE:
July 2013
Science! It's a Girl Thing Camp: Building Blocks of Life
Texas Tech University, Lubbock, TX
Role: Design and teach a course to rising 9th, 10th and 11th grade girls
about basic genetic and molecular biology topics such as DNA, the
Central Dogma, protein folding, enzymes, mitosis and meiosis, and
genetic inheritance
Enrollment: 8 students
June 2013
Science! It's a Girl Thing Camp: Building Blocks of Life
Texas Tech University, Lubbock, TX
Role: Design and teach a course to rising 5th and 6th grade girls
about basic genetic and molecular biology topics such as DNA, enzymes,
mitosis and meiosis, and genetic inheritance.
Enrollment: 12 Students
June 2013-Present
Research Mentor to Undergraduate Student
Texas Tech University, Lubbock, TX
Role: Explain background material; demonstrate how to do laboratory
techniques such as cell culture work, Real-Time PCR, RNA extraction,
and Western Blotting.
April 2013-June 2013
Research Training for a Visiting International Graduate Student
Texas Tech University, Lubbock, TX
Role: Explain background material; demonstrate how to do laboratory
techniques such as cell culture work, Real-Time PCR, RNA extraction,
and Western Blotting
Spring 2011-2012
Biology 140: Organization and Function of the Cell
University of Tennessee, Knoxville, TN
Role: Conduct laboratory experiments, lead class discussions, prepare
and grade examinations
Enrollment: 40 students (Spring '11), 44 students (Fall '11),
50 students (Spring '12)
Summer 2011
Biology 140: Organization and Function of the Cell
University of Tennessee, Knoxville, TN
Role: Curriculum development: Established teaching methods and
materials for laboratory setting
Fall 2010
Biology 101: Humankind in the Biotic World
University of Tennessee, Knoxville, TN
Role: Instruct laboratory work, and grade assignments
Enrollment: 55 students
LEMIEUX, MONIQUE J.
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AWARDS AND FELLOWSHIPS:
2013-2014
Scholarship, C. R. and Virginia Hutcheson Scholarship Endowment in Human
Sciences, Texas Tech University, Lubbock, TX.
2013
Travel Award, ASN/Maximizing Access to Research Careers (MARC) Travel
Award, Funded by the Federation of American Societies for Experimental
Biology (FASEB)/MARC and American Society for Nutrition (ASN) .
Experimental Biology Meeting, Boston, MA.
2012
Travel Award, PhD Student Sponsorship for the Institute on Teaching and
Mentoring, Sponsored by the Federation of American Societies for Experimental
Biology/Minority Access to Research Careers. Institute on Teaching and
Mentoring, Tampa, FL.
2011
Travel Award, PhD Student Sponsorship for the Institute on Teaching and
Mentoring, Sponsored by the Federation of American Societies for Experimental
Biology/Minority Access to Research Careers. Institute on Teaching and
Mentoring, Atlanta, GA.
2010
Travel Award, Summer School on Methods and Applications of Small Angle
Neutron Scattering and Neutron Reflectivity, National Institute of Standards and
Technology Center for Neutron Research, Gaithersburg, MD
2010
Travel Award, ASBMB Graduate Minority Travel Award Program, Funded by
the Federation of American Societies for Experimental Biology/Minority Access
to Research Careers. Experimental Biology Meeting, Anaheim, CA.
2009-2010
Fellowship, NIH Program for Excellence & Equity in Research (PEER),
University of Tennessee, Knoxville, TN
2009
Invited Student Award, Summer School in Biophysics at ORNL: Computational
and Experimental Challenges, Oak Ridge National Laboratory, August 2009,
Knoxville, TN
PUBLICATIONS:
1. Monique LeMieux, Arwa Al-Jawadi, Shu Wang, and Naima Moustaid-Moussa . EB 2013
Symposium overview: Metabolic Profiling in Nutrition and Metabolic Disorders. Advances in
Nutrition. In Press; tentative publication date: Sept. 2013
2. Nalin Siriwardhana, Nishan S. Kalupahana, Maria Cekanova, Monique LeMieux, Betty
Greer, and Naima Moustaid-Moussa (2013). Modulation of adipose tissue inflammation by
bioactive food compounds. Journal of Nutritional Biochemistry, 24:4; 613-623.
LEMIEUX, MONIQUE J.
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3. Wenting X. Carroll, Nishan S. Kalupahana, Suzzanne L. Booker, Nalin Siriwardhana,
Monique J. LeMieux, Arnold M. Saxton, Naima Moustaid-Moussa (2013). Angiotensinogen
gene silencing reduces lipid accumulation and inflammatory markers in cultured adipocytes.
Frontiers in Endocrinology/Diabetes. 4:10.
4. Elizabeth Schussler, Jan Hudson, Monique LeMieux, Sudhir Naswa (2011). Biology 140:
Organization and Function of the Cell Laboratory Manual. University of Tennessee,
Knoxville, TN.
RESEARCH SUPPORT:
1. “Structural Analysis of Z α1-Antitrypsin Aggregation.” Principal Investigator,
Physicians’ Medical Education and Research Foundation (PMERF) Research Grant,
Awarded: 2011-2012
2. “A Screening Assay for Z α1-Antitrypsin Aggregation”. Principal Investigator,
Physicians’ Medical Education and Research Foundation (PMERF) Research Grant,
Awarded: 2009-2012
IVITED TALKS:
1. “Unraveling the Z α1-Antitrypsin Polymerization Puzzle.” ASBMB Biochemistry &
Molecular Biology Honor Society. University of Tennessee, April 2011. Knoxville, TN.
2. “Screening Assay for Z Alpha1-Antitrypsin Aggregation.” Harold Cones Seminar Series.
Christopher Newport University, March 2010. Newport News, VA.
POSTER PRESENTATIONS:
1. " Eicosapentaenoic acid Prevents High Fat Diet-Induced Metabolic Disorders:
Genomic and Metabolomic Analyses of Underlying Mechanisms in Fat Tissue"
Experimental Biology Meeting, April 2013, Boston, MA.
2. "Genomic and Metabolomic Analyses of Underlying Mechanisms in Eicosapentaenoic
acid Prevention of High Fat Diet-Induced Metabolic Disorders." 12th Annual Graduate
Student Research Poster Competition, Organized by Texas Tech University Graduate
School. March 2013. Lubbock, TX
3. " Eicosapentaenoic acid Prevents High Fat Diet-Induced Metabolic Disorders:
Genomic and Metabolomic Analyses of Underlying Mechanisms in Fat Tissue"
25th Student Research Week, Organized by Texas Tech Health Sciences Center. March
2013. Lubbock, TX
4. “Screening for Z α1-Antitrypsin aggregation inhibitors” Summer School on Methods and
Applications of Small Angle Neutron Scattering and Neutron Reflectivity, Organized by the
National Institute of Standards and Technology Center for Neutron Research, May 2010,
Gaithersburg, MD
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5. “A Screening Assay for Z α1-Antitrypsin aggregation,” Experimental Biology Meeting,
April 2010, Anaheim, CA
6. “Using Kinetic Methods to Evaluate the Role of an Intrinsically Disordered Domain in
Vitronectin Binding to PAI-1” Summer School in Biophysics at ORNL: Computational and
Experimental Challenges, Organized by Oak Ridge National Laboratory, August 2009,
Knoxville, TN
TEACHING WORKSHOPS
1. Experienced GTA Panelist. “New Graduate Teaching Assistants / Associates
(GTAs) Orientation.” Hosted by the Graduate School. University of Tennessee.
Knoxville, TN. August 2012
2. Participant. “Best Practices in Teaching Program.” Hosted by the Graduate School.
University of Tennessee. Knoxville, TN. Spring 2012.
3. Participant. “Effective College Teaching Workshop.” Hosted by The Program for
Excellence and Equality in Research (PEER). University of Tennessee. Knoxville,
TN. April 2010
4. Participant. New Biology Graduate Student Orientation: “Biology Best Teaching
Practices.” University of Tennessee. Knoxville, TN. August 2010.
EXTRACURICULLAR
Student Representative, Basic Science Section of The Obesity Society, 2012-2013
Student Member, The Obesity Society, 2012-Present
Student Member, American Society for Nutrition, 2012-Present
Equity & Diversity Chair, Graduate Student Senate, 2011-2012
GST Representative, Graduate Student Senate, 2011-2012
President, Graduate Student Organization for the GST program, 2010-2012
Student Member, American Society for Biochemistry and Molecular Biology, 2009-2010
Social Chair, Graduate Student Organization for the GST program, 2009-2010
Student Host for Perspective Students during the GST Spring Retreat 2009-2010
Student Mentor for Incoming GST Students 2008-2011